Download or read book Current Review of Chinese Medicine written by Ping-Chung Leung and published by World Scientific. This book was released on 2006 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The second volume of this book series on the modern practice of Chinese medicine continues with the focus on evidence-based TCM research. It is even more focused than the preceding one ? providing detailed information about the best sources of herbal supply required for research and drug development purposes. Herbal supply has always been a major concern for TCM researchers because it is difficult to ensure that the supply is of the best quality. Another highlight of the book are the special reviews on the state of Good Agricultural Practice

Download or read book Current Review Of Chinese Medicine Quality Control Of Herbs And Herbal Material written by Ping-chung Leung and published by World Scientific. This book was released on 2006-05-02 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume of this book series on the modern practice of Chinese medicine continues with the focus on evidence-based TCM research. It is focused on detailed information about the best sources of herbal supply and its quality control required for research and drug development purposes. Herbal quality has always been a major concern for TCM researchers because it is difficult to know which is of the best quality. Some other popular topics are also entertained.

Download or read book Traditional Herbal Medicine Research Methods written by Willow J.H. Liu and published by John Wiley & Sons. This book was released on 2011-03-29 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the methodology for collection and identification of herbal materials, extraction and isolation of compounds from herbs, in vitro bioassay, in vivo animal test, toxicology, and clinical trials of herbal research. To fully understand and make the best use of herbal medicines requires the close combination of chemistry, biochemistry, biology, pharmacology, and clinical science. Although there are many books about traditional medicines research, they mostly focus on either chemical or pharmacological study results of certain plants. This book, however, covers the systematic study and analysis of herbal medicines in general – including chemical isolation and identification, bioassay and mechanism study, pharmacological experiment, and quality control of the raw plant material and end products.

Download or read book Chinese Herbal Drug Research Trends written by Felix M. Ching and published by Nova Publishers. This book was released on 2007 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chinese Herbal Medicine -- part of a larger healing system called Traditional Chinese Medicine (TCM), which also includes acupuncture, massage dietary advice and exercise. TCM is a popular method of treatment -- is actually called Chinese Drug Therapy in China because it uses a wide variety of substances and therapeutic modalities. Plant, animal and mineral substances are all included in the Materia Medica of Chinese Drug Therapy. The earliest uses date back at least 4000 years to the Shang dynasty. Characters representing medicinal substances have been found carved into oracular bone fragments. These were used diagnostically by the Wu Shaman of this time. The earliest materia Medica, the Sheng Nung Peng Tsao, recorded over 10,000 medicinal substances. While there seems to be an almost unlimited amount of medicinal substances, the most commonly used number around 200. Increased attention has begun being given to the field due to several factors: The apparent success stories in many cases; The failure of Western medicine in many disorders; and Realisation on the part of Western researchers that successful drugs can be designed on the basis of Chinese herbal drugs. This new book presents the latest research in the field.

Download or read book Pharmacological Activity based Quality Control of Chinese Herbs written by and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are the most successful source of drugs. Of the 877 small-molecule new chemical entities introduced between 1981 and 2002, roughly half were natural products, semi-synthetic natural product analogues or natural mimics. Chinese herbs (traditional Chinese medicines, TCMs) have been used for prevention and treatment of diseases for thousands years. It has been attracting intensive attention in the trends of back to nature. As herbal medicines, the conditions of growth, harvest time, process and storage etc. will undoubtedly affect the presence and concentration of the bioactive constituents, thus affecting their quality and efficacy. Up to date, there are few books focussing on the relationship, which is the bridge between TCM and modern medical science, of traditional clinic uses, pharmacological activities and quality control of Chinese herbs. Unfortunately, bioactive compounds in Chinese herbs are usually not or only partially known. Actually, the active compounds considered in Chinese herbs may be different according to their clinical indication. In addition, it is considered that the curative effect of Chinese herbs is an integrative result of a number of bioactive compounds. Therefore, how to control the quality is a big problem. We would like to discuss the quality control based on their traditional clinical uses and pharmacological activities in this book, which is the fundamental step towards developing and modernising such products into evidence based medicines. It will also help the peoples to understand TCMs in modern scientific angles. This book is designed primarily as a textbook for or adjunct to course in herbal remedies, food safety or quality control of herbs. It is also a professional reference whom is in the area of drug discovery, pharmaceutical analysis and food chemistry.

Download or read book Quality Control Methods for Medicinal Plant Materials written by World Health Organization and published by World Health Organization. This book was released on 1998 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of test procedures for assessing the identity, purity, and content of medicinal plant materials, including determination of pesticide residues, arsenic and heavy metals. Intended to assist national laboratories engaged in drug quality control, the manual responds to the growing use of medicinal plants, the special quality problems they pose, and the corresponding need for international guidance on reliable methods for quality control. Recommended procedures - whether involving visual inspection or the use of thin-layer chromatography for the qualitative determination of impurities - should also prove useful to the pharmaceutical industry and pharmacists working with these materials.

Download or read book WHO Guidelines on Good Agricultural and Collection Practices GACP for Medicinal Plants written by Organización Mundial de la Salud and published by World Health Organization. This book was released on 2003-12-16 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal plant materials are supplied through collection from wild populations and cultivation. Under the overall context of quality assurance and control of herbal medicines WHO developed the Guidelines on good agricultural and collection practices (GACP) for medicinal plants providing general technical guidance on obtaining medicinal plant materials of good quality for the sustainable production of herbal products classified as medicines. These guidelines are also related to WHO's work on the protection of medicinal plants aiming promotion of sustainable use and cultivation of medicinal plants. The main objectives of these guidelines are to: (1) contribute to the quality assurance of medicinal plant materials used as the source for herbal medicines to improve the quality safety and efficacy of finished herbal products; (2) guide the formulation of national and/or regional GACP guidelines and GACP monographs for medicinal plants and related standard operating procedures; and (3) encourage and support the sustainable cultivation and collection of medicinal plants of good quality in ways that respect and support the conservation of medicinal plants and the environment in general. These guidelines concern the cultivation and collection of medicinal plants and include certain post-harvest operations. Good agricultural and collection practices for medicinal plants are the first step in quality assurance on which the safety and efficacy of herbal medicinal products directly depend. These practices also play an important role in protection natural resources of medicinal plants for sustainable use.

Download or read book Evaluation of Herbal Medicinal Products written by Pulok K. Mukherjee and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book presents a structural approach to the evaluation of herbal medicinal products for quality, safety and efficacy. There has been an enormous growth in the market for herbal medicinal products in the last twenty five years. However the rediscovery of natural substances with therapeutic potential has raised questions of quality, safety and efficacy on the part of the consumer and also from health professionals. This book brings together current thinking and practice in these areas highlighting current research. In the light of increasing legislation to enforce better standards for these products and the demand by legislators and the public for assurance of safe and effective use, this book seeks to provide a state-of-the-art review, which informs and guides those who seek to promote their use. This book also gives an overview of the place of ethno pharmacology in the development of herbal medicinal products and discusses good agricultural and collection practices, marker analysis and stability testing which contribute to assessment of good quality of these materials." -- Publisher description.

Download or read book Drug Discovery and Evaluation Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

Download or read book Current Review of Chinese Medicine written by Ping-Chung Leung and published by World Scientific. This book was released on 2006 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The second volume of this book series on the modern practice of Chinese medicine continues with the focus on evidence-based TCM research. It is even more focused than the preceding one ? providing detailed information about the best sources of herbal supply required for research and drug development purposes. Herbal supply has always been a major concern for TCM researchers because it is difficult to ensure that the supply is of the best quality. Another highlight of the book are the special reviews on the state of Good Agricultural Practice

Download or read book Quality Control and Evaluation of Herbal Drugs written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2019-05-30 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Download or read book Quality Control of Herbal Medicines and Related Areas written by Yukihiro Shoyama and published by BoD – Books on Demand. This book was released on 2011-11-04 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of this thematic issue provide a comprehensive summary of most recent knowledge and references on quality control in wide fields. Quality control is essential for natural products like natural medicine and related food products. In this issue fifteen chapters have been included, discussing in detail various aspects of quality control. It will certainly prove useful not only for phytochemical researchers, but also many scientists working in numerous fields. Much effort has been invested by the contributors to share current information. Without their efforts and input 'Quality Control of Herbal Medicine and Related Areas' could not exist.

Download or read book Neurobiology of Chinese Herb Medicine written by and published by Academic Press. This book was released on 2017-08-11 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Chinese Herb Medicine, Volume 135 is a valuable book for anyone interested in alternative medicine or the scientific research surrounding ancient herbal medicine. This updated volume in the series includes chapters that delve into timely topics, including the Effects of Lycium Barbarum on the Visual System, the Effect of Chinese Herbal Medicine on Alzheimer’s Disease, the Effect and Mechanism of Chinese Herbal Medicine on Parkinson’s Disease, the Neurobiology of Chinese Herbal Medicine on Major Depressive Disorder, the Treatment of Insomnia with Traditional Chinese Herbal Medicine, and the Metabolic Factors and Adult Neurogenesis: Impacts of Chinese Herbal Medicine on Brain Repair in Neurological Diseases. This series is ideal for Chinese herbal medicine practitioners who are working in a clinical environment, although the clinical applications of Chinese medicinal herbs presented provide useful references and guidance for any clinical practice that specializes in the treatment of various conditions. Presents a wealth of information on the use of Chinese herbal medicine and its application to many conditions Provides basic research and clinical studies of Chinese herbal medicines, either as compounds/extracts or formulas Sheds light on possible action mechanisms of many Chinese herbal medicines

Download or read book Evidence Based Validation of Herbal Medicine written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2022-07-12 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Download or read book Dietary Chinese Herbs written by Yanze Liu and published by Springer Science & Business Media. This book was released on 2015-05-18 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs. Authored by native experts in the field, the reader is introduced to each herb with a brief chronological review of Chinese literature on dietary herb uses, with chapters dedicated to each selected herb including color photos for each herb. In addition, Chinese characters as well as the Latin botanical name indices, and chemical structures for the known active compounds are also provided. The clear layout examines the health benefits that have been studied for centuries, including current clinical and toxicological data. A wide range of Traditional Chinese Medicine (TCM) herbs are investigated for their suitability into daily diets for maintaining general wellness or disease prevention. In the past decades, natural health products, dietary supplements, functional foods, or nutraceuticals have emerged in the West due to the increasing demand for non-pharmaceutical healthcare products. Traditional Chinese Medicine disease prevention and treatment incorporates the use of foods, and herbal medicine in an integrated manner, and thus the dietary Chinese herbs in used in TCM for thousands of years could be sources for developing new, effective, and safe ingredients to capture the rapidly expanding opportunity in the global market place.

Download or read book Advanced Technologies for the Quality Control and Standardization of Plant Based Medicines written by Jiang Xu and published by Frontiers Media SA. This book was released on 2020-06-18 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herbs and herbal products are of paramount importance for human health. To beable to guarantee safety and quality, standards and testing methods are needed.Pharmacopoeias contain quality control protocols setting the standards which arethen required by governments. The quality traits are many, including the intrinsicvariables of medicinal plant, e.g. the levels of the active compounds, and the absenceof possibly natural occurring toxic compounds. On the other hand, many qualitytraits are related to agricultural conditions and practices, or to the harvesting andpost-harvest processing. With so many variables, quality control of the end productbecomes extremely complex, time consuming and costly. To ensure the quality ofmedicinal plants for human consumption quality management -the use of “goodpractices” at each step, from seed to final product- becomes a crucial aspect. In general, quality control includes the inspection of the product’s identity, purity,and content, based on its physical, chemical or biological properties. To ensure thequality of herbal medications, criteria such as botanical quality, type of preparation,physical constants, adulteration, contaminants, chemical constituents, pesticidesresidues et al. should be examined. Meanwhile, authentication of herbs is neededto avoid possible adulteration or contaminating plants, even toxic herbs such asAristolochia species. Many of the methods are long standing, such as microscopy incombination with color reactions, but some 50 years ago chromatography developedas a major tool for both qualitative and quantitative analysis of herbal preparations.Nowadays, research is working on the improvement of these methods and on thedevelopment of novel tools. For instance, next generation sequencing and mass spectrometry imaging, areemerging as new technologies for the quality control of herbal medicines. Withthese technologies, quick testing of herbal products and of mixed herbal powderpreparations, including the testing for specific plant parts (botanical drugs), can beachieved. Also, novel chemical tools such as metabolomics and Near Infrared Red(NIR) spectroscopy are being developed as powerful tools to identify and to linkthese with activity by using chemometric tools such as multivariate analysis. Finally,progress of informatic tools such as machine learning helps to deal with the big datagenerated by sequencing or mass spectrometry. However, these new technologies,like all other new born technologies, should be tested and perfected for a broaderrange of products.

Download or read book Pharmaceutical Applications of Raman Spectroscopy written by Slobodan Sasic and published by John Wiley & Sons. This book was released on 2007-10-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics.