Download or read book Electron Transfer Proteins written by Toshiko Ichiye and published by CRC Press. This book was released on 2015-02-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A molecular understanding of electron transfer is crucial to understanding the molecular basis of metabolic processes in which electron transfer is essential, diseases involving these processes, and drug design targeting these processes. This book provides a cohesive and comprehensive discussion of computational methods used for electron transfer proteins and what has been learned from such studies for the first time in a book. It also gives an overview of results from theory, computation, and experiment about electron transfer proteins. This resource also includes strategies for studying metal sites that have not been examined computationally.
Download or read book Computation of Electron Transfer in Proteins written by Dmitry Medvedev and published by . This book was released on 2002 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Protein Electron Transfer written by Dr Derek Bendall and published by Garland Science. This book was released on 2020-07-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique; the factual content and ideas it expounds are only just beginning to be touched upon in standard texts. Protein Electron Transfer is a major collaborative effort by leading experts and explores the molecular basis of the rapidly expan
Download or read book Computational and Experimental Insights in Redox Coupled Proton Pumping in Proteins written by Vivek Sharma and published by Frontiers Media SA. This book was released on 2021-10-29 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Simple Effective Model for Calculating Electron Transfer Rates in Proteins written by Christopher C. Page and published by . This book was released on 2001 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proteins written by David M. Leitner and published by CRC Press. This book was released on 2009-09-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling can provide a wealth of insight into how energy flow in proteins mediates protein function. Computational methods can also address fundamental questions related to molecular signaling and energy flow in proteins. Proteins: Energy, Heat and Signal Flow presents state-of-the-art computational strategies for studying energy redi
Download or read book Computational Studies of Iron sulfur Electron Transfer Proteins written by Michael James Fajardo and published by . This book was released on 2004 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Studies of Electron Transfer in Multi Heme Proteins written by Xiuyun Jiang and published by . This book was released on 2019 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multi-heme proteins are fascinating biomolecules that bind several redox-active heme cofactors in close distance to shuttle electrons across the bacterial membrane. Yet, the kinetics and time scales on which these electron transfer (ET) events occur is not well known and difficult to probe experimentally. The central aim of this thesis is to compute and to quantify heme-heme ET rate constants and electron flux through solvated multi-heme proteins. To this end, density functional theory and molecular dynamics simulation are deployed to compute heme-heme ET parameters in the framework of (non-adiabatic) Marcus theory, the central theory underlying such ET events. Three ubiquitous multi-heme proteins have been studied, which bind 4 and 10 heme cofactors. Our calculations revealed that electron transfer through these proteins is strongly enhanced by cysteine side chains that are inserted in the space between heme groups. We believe this to be a general design principle in this family of proteins for acceleration of ET steps that would otherwise be too slow for biological respiration. Our computational protocol has been verified via comparing our predicted time scale of heme-heme ET with the corresponding ET rate constant measured from pump-probe spectroscopy. The maximum, protein-limited electron flux is ≈ 10^5 - 10^6 s^-1. Such efficiency in long-range electron transfer indicates that multi-heme proteins are promising candidates for biological nano-electronic devices.
Download or read book A Computational Study in the Thermodynamic and Dynamic Properties of Electron Transfer Proteins written by David N. LeBard and published by . This book was released on 2008 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Investigation of Amino Acid Radicals Involved in Electron Transfer Pathways in Proteins written by Caterina Bernini and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reduction Potential Properties of Electron Transfer Proteins written by Kelly Nora Tran and published by . This book was released on 2018 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, a method for calculating the reduction potentials of metalloproteins is presented in which the redox site or inner sphere contribution is calculated by density functional theory (DFT) and the protein and solvent environment or outer sphere contribution is calculated by Poisson-Boltzmann (PB) continuum electrostatics. Reduction potentials calculated using the DFT+PB method are in good agreement with the experimental values for and the nine Fe-S clusters in respiratory complex I. Moreover, the method used here is a useful computational tool to study other questions about complex I. In addition, the method is being extended to the blue copper proteins.
Download or read book Biological Electron Transfer Chains Genetics Composition and Mode of Operation written by G.W. Canters and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: From May 3-7,1997, the NATO Advanced Research Workshop on 'Biological Electron Transfer Chains' was organized in Tomar, Portugal. In the application for support the choice of the topic was justified as follows: "[Until recently efforts] have concentrated on the study of the structure and function of individual redox enzymes and proteins. Enough information is now available to make a start with the study of biological electron transfer (E1) at the next higher level of organization, that of the complete ET chain." The interest in the workshop was high: the majority of participants had registered before the workshop was formally announced, which illustrates the popularity of the topic within the biochemical and biophysical communities. The present volume contains a number of reports based on the lectures presented by the key speakers during the meeting. The workshop dealt with the following three themes: a) Electron transfer, which is the subject of Chapter 1. The analysis of ET at the molecular level is still fundamental for an understanding of how ET chains operate in vivo. After 40 years of research the contours of the subject are becoming clear now. b) Bacterial redox chains. This is the subject of Chapter 2. Its contents show how complicated these chains can be, often involving a number of gene clusters. Our understanding of the regulatory aspects and control mechanisms of these chains is only in its beginning.
Download or read book Protein Electron Transfer written by Dr Derek Bendall and published by Garland Science. This book was released on 2020-07-24 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique; the factual content and ideas it expounds are only just beginning to be touched upon in standard texts. Protein Electron Transfer is a major collaborative effort by leading experts and explores the molecular basis of the rapidly expan
Download or read book Computational Biochemistry and Biophysics written by Oren M. Becker and published by CRC Press. This book was released on 2001-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret b
Download or read book Computational Studies of Electron Transfer Proteins written by Yan Luo and published by . This book was released on 2011 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron-sulfur proteins are an important class of electron transfer proteins found universally in living organisms, serving vital roles in the electron transport chains of cellular energy utilization. Determining the molecular basis of electron transfer properties of these proteins is important in understanding how they promote fast and efficient energy flow in the cell.
Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1991-03-15 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of a series devoted to understanding the relationship between the chemistry of metals and life processes, the present volume offers contributions by 25 scientists covering mechanistic considerations, electron tunneling pathways, photoinduced and stereoselective effects in electron transfer reac
Download or read book Metalloproteins written by Art E. Cho and published by CRC Press. This book was released on 2015-04-17 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous essential biological functions involve metalloproteins; therefore, understanding metalloproteins and how to manipulate them is significant in the biological and medical fields. An examination of current research, Metalloproteins: Theory, Calculations, and Experiments explores the interplay between theory and experiment, detailing the role
