Download or read book The Business of Healthcare Innovation written by Lawton Robert Burns and published by Cambridge University Press. This book was released on 2005-08-25 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Business of Healthcare Innovation is the first wide-ranging analysis of business trends in the manufacturing segment of the health care industry. In this leading edge volume, Professor Burns focuses on the key role of the 'producers' as the main source of innovation in health systems. Written by professors of the Wharton School and industry executives, this book provides a detailed overview of the pharmaceutical, biotechnology, genomics/proteomics, medical device and information technology sectors. It analyses the market structures of these sectors as well as the business models and corporate strategies of firms operating within them. Most importantly, the book describes the growing convergence between these sectors and the need for executives in one sector to increasingly draw upon trends in the others. It will be essential reading for students and researchers in the field of health management, and of great interest to strategy scholars, industry practitioners and management consultants.

Download or read book Cell Based Therapy for Degenerative Retinal Disease written by Marco A. Zarbin and published by Springer. This book was released on 2019-03-01 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.

Download or read book Human Embryonic Stem Cells written by Arlene Chiu and published by Springer Science & Business Media. This book was released on 2003-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Download or read book Stem Cell and Gene Based Therapy written by Alexander Battler and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Download or read book The Assassination of Representative Leo J Ryan and the Jonestown Guyana Tragedy written by United States. Congress. House. Committee on Foreign Affairs. Staff Investigative Group and published by . This book was released on 1979 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Beyond Biocentrism written by Robert Lanza and published by BenBella Books, Inc.. This book was released on 2016-05-03 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocentrism shocked the world with a radical rethinking of the nature of reality. But that was just the beginning. In Beyond Biocentrism, acclaimed biologist Robert Lanza, one of TIME Magazine's "100 Most Influential People in 2014," and leading astronomer Bob Berman, take the reader on an intellectual thrill-ride as they re-examine everything we thought we knew about life, death, the universe, and the nature of reality itself. The first step is acknowledging that our existing model of reality is looking increasingly creaky in the face of recent scientific discoveries. Science tells us with some precision that the universe is 26.8 percent dark matter, 68.3 percent dark energy, and only 4.9 percent ordinary matter, but must confess that it doesn't really know what dark matter is and knows even less about dark energy. Science is increasingly pointing toward an infinite universe but has no ability to explain what that really means. Concepts such as time, space, and even causality are increasingly being demonstrated as meaningless. All of science is based on information passing through our consciousness but science hasn't the foggiest idea what consciousness is, and it can't explain the linkage between subatomic states and observation by conscious observers. Science describes life as a random occurrence in a dead universe but has no real understanding of how life began or why the universe appears to be exquisitely designed for the emergence of life. The biocentrism theory isn't a rejection of science. Quite the opposite. Biocentrism challenges us to fully accept the implications of the latest scientific findings in fields ranging from plant biology and cosmology to quantum entanglement and consciousness. By listening to what the science is telling us, it becomes increasingly clear that life and consciousness are fundamental to any true understanding of the universe. This forces a fundamental rethinking of everything we thought we knew about life, death, and our place in the universe.

Download or read book The Emergence of Organizations and Markets written by John F. Padgett and published by Princeton University Press. This book was released on 2012-10-14 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: The social sciences have sophisticated models of choice and equilibrium but little understanding of the emergence of novelty. Where do new alternatives, new organizational forms, and new types of people come from? Combining biochemical insights about the origin of life with innovative and historically oriented social network analyses, John Padgett and Walter Powell develop a theory about the emergence of organizational, market, and biographical novelty from the coevolution of multiple social networks. In the short run, they argue, actors make relations, but in the long run, they argue, actors make actors. Organizational novelty arises from spillover across intertwined networks, which tips reproducing biographical and production flows. This theory is developed through formal deductive modeling and through a wide range of careful and original historical case studies, ranging from early capitalism and state formation, to the transformation of communism, to the emergence of contemporary biotechnology and Silicon Vally. -- from back cover.

Download or read book Ryan s Retina E Book written by Charles P. Wilkinson and published by Elsevier Health Sciences. This book was released on 2017-04-17 with total page 2893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.

Download or read book Corneal Regeneration written by Jorge L. Alió and published by Springer. This book was released on 2019-02-20 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.

Download or read book A Dictionary of Medicine and the Allied Sciences written by Alexander Duane and published by . This book was released on 1900 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biocentrism written by Robert Lanza and published by ReadHowYouWant.com. This book was released on 2011 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Lanza is one of the most respected scientists in the world a US News and World Report cover story called him a genius and a renegade thinker, even likening him to Einstein. Lanza has teamed with Bob Berman, the most widely read astronomer in the world, to produce Biocentrism, a revolutionary new view of the universe. Every now and then a simple yet radical idea shakes the very foundations of knowledge. The startling discovery that the world was not flat challenged and ultimately changed the way people perceived themselves and their relationship with the world. For most humans of the 15th century, the notion of Earth as ball of rock was nonsense. The whole of Western, natural philosophy is undergoing a sea change again, increasingly being forced upon us by the experimental findings of quantum theory, and at the same time, toward doubt and uncertainty in the physical explanations of the universes genesis and structure. Biocentrism completes this shift in worldview, turning the planet upside down again with the revolutionary view that life creates the universe instead of the other way around. In this paradigm, life is not an accidental byproduct of the laws of physics. Biocentrism takes the reader on a seemingly improbable but ultimately inescapable journey through a foreign universe our own from the viewpoints of an acclaimed biologist and a leading astronomer. Switching perspective from physics to biology unlocks the cages in which Western science has unwittingly managed to confine itself. Biocentrism will shatter the readers ideas of life--time and space, and even death. At the same time it will release us from the dull worldview of life being merely the activity of an admixture of carbon and a few other elements; it suggests the exhilarating possibility that life is fundamentally immortal. The 21st century is predicted to be the Century of Biology, a shift from the previous century dominated by physics. It seems fitting, then, to begin the century by turning the universe outside-in and unifying the foundations of science with a simple idea discovered by one of the leading life-scientists of our age. Biocentrism awakens in readers a new sense of possibility, and is full of so many shocking new perspectives that the reader will never see reality the same way again.

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Download or read book Essentials of Stem Cell Biology written by Robert Lanza and published by Academic Press. This book was released on 2009-06-05 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. - Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries - Contributions by Nobel Laureates and leading international investigators - Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough - Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate - Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Download or read book Retinal Pigment Epithelium in Health and Disease written by Alexa Karina Klettner and published by Springer Nature. This book was released on 2020-01-01 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium (RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development of RPE in diagnostics and therapy are covered, as well as some practical knowledge about RPE experimental models. Retinal Pigment Epithelium in Health and Disease highlights new findings of RPE research and includes the state-of-the-art knowledge of each RPE topic presented. This important feature sets this book apart from other publications, with the chapters following a design which leads from the general to the specific, to give a precise collection of the facts known. The chapters are written by well-known experts that are currently active in the field as consultants, basic scientists, and group leaders, providing expert guidance on the current aspects and future outlooks of this topic.

Download or read book Vitreoretinal Disorders written by Glenn Yiu and published by Springer. This book was released on 2018-12-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the newest trends, concepts, and advancements in the management of vitreo-retinal conditions. The field of retina is rapidly changing, with new advances ranging from stem cell therapy, gene therapy and editing, new drug targets, novel delivery systems, and innovative technologies in advanced ocular imaging and surgical techniques. The goal is to provide a way to update practitioners and trainees on how the field of retina is changing. Areas of focus include new technologies, particularly in ocular imaging and vitreo-retinal surgery, major new clinical trials, particularly those that are shifting practice patterns or addressing novel therapies, and novel research that is altering the classification and diagnosis of retinal conditions, as well as management strategies and prognostic predictors for vitreo-retinal diseases. This volume is essential reading for generalist and specialist ophthalmologists and useful for residents and fellows training in various subspecialties.

Download or read book Global Bioethics The Impact of the UNESCO International Bioethics Committee written by Alireza Bagheri and published by Springer. This book was released on 2015-10-22 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The UNESCO International Bioethics Committee is an international body that sets standards in the field of bioethics. This collection represents the contributions of the IBC to global bioethics. The IBC is a body of 36 independent experts that follows progress in the life sciences and its applications in order to ensure respect for human dignity and freedom. Currently, some of the topics of the IBC contributions have been discussed in the bioethics literature, mostly journal articles. However, this is a unique contribution by the scholars who developed these universal declarations and reports. The contributors have not only provided a scholarly up to date discussion of their research topics, but as members of the IBC they have also discussed specific practical challenges in the development of such international documents. This book will be suited to academics within bioethics, health care policy and international law.

Download or read book Global Perspectives on Stem Cell Technologies written by Aditya Bharadwaj and published by Palgrave Macmillan. This book was released on 2018-06-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes as its point of departure a humble cell lying on the intersection of ideas as diverse and yet interlaced as life, knowledge, commerce, governance, and ethics. It seeks to deepen the understanding of stem cell entities and the concerns, hopes, and aspirations that shape and make them viable therapeutic entities in the context of rapid globalization. Several key intersections between individual, group, and institutional relationships have become central to locating and debating the production of stem cells today. This edited collection addresses three overarching concerns: regenerating the notion of ethics, the emerging therapeutic horizons, and the position of the patient. As a whole this book seeks to explain how stem cells are accommodated, contested, and used in contemporary India and around the globe through an informed unpacking of issues underpinning contestation and promotion bestriding these technological developments. The authors offer a truly multi-disciplinary perspective, stimulating conversation between the social sciences, biological sciences and the patient. The concerns expressed and highlighted by these conversations are embedded in a vast geo-political expanse stretching from India to Euro-America and will be of great interest to academics and practitioners across fields including science technology studies, medicine and international development.