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Book Inhalation Exposure Pathways for Polybrominated Diphenyl Ethers

Download or read book Inhalation Exposure Pathways for Polybrominated Diphenyl Ethers written by Scot Waye and published by . This book was released on 2008 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many chemicals off-gas or leech into indoor environments from sources such as consumer products, furnishings, and building materials. An understanding of the pathways from the sources to human exposure is vital in order to implement control strategies and lower exposure. Objects containing Brominated flame retardants (BFRs), one class of semivolatile organic compounds (SVOCs), burn more slowly during combustion. BFRs, especially polybrominated diphenyl ethers (PBDEs), are used in electronic devices including casings and circuit boards. Heat from internal circuitry increases the BFR vapor pressure and the partition coefficient, enhancing its transport out of the substrate and into the indoor environment. In this work, a computer tower in an office setting provides a case study to examine the emissions of, and exposure to, PBDEs. the case of a computer tower, the cooling fan increases the mass transfer coefficient, further increasing emissions. During computer use, the emission rate of PBDEs from the interior of the case is more than double the emission rate from the exterior of the case due to elevated internal temperatures and higher mass transfer due to the cooling fan. The concentration of PBDEs in the room air increases 40 - 80% for every 5°C increase inside the computer case, depending on the PBDE congener. Such enhanced emissions are a concern since recent studies have shown adverse health effects of PBDEs on human health. The major contributions of this work are: A model was developed that is useful for SVOC emissions for various heat and mass transfer situations, including diffusion through the slab and convective boundary conditions on each side of the slab, which may be simplified if the situation warrants; A systematic propagation of the uncertainties and variability of the model parameters was accomplished by using a Monte Carlo method for the input of the parameters into the model; A polydisperse indoor particle distribution was used as a sink, identifying the size-discretized particle phase PBDE concentration; An exposure assessment showed that the inhalation pathway for PBDEs in the gas and particulate phases is relevant and that the particulate phase exposure is dominant.

Book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low Dose Toxicity from Endocrine Active Chemicals

Download or read book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low Dose Toxicity from Endocrine Active Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.

Book Risk Assessment of Polybrominated Diphenyl Ethers

Download or read book Risk Assessment of Polybrominated Diphenyl Ethers written by Kemikalieinspektionen and published by . This book was released on 1994 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Risk Assessment of Polybrominated Biphenyls and Polybrominated Diphenyl Ethers

Download or read book Risk Assessment of Polybrominated Biphenyls and Polybrominated Diphenyl Ethers written by E. J. van de Plassche and published by . This book was released on 1994 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Preliminary Risk Assessment of Polybrominated Diphenyl Ethers

Download or read book The Preliminary Risk Assessment of Polybrominated Diphenyl Ethers written by Nalini Suresh and published by . This book was released on 2009 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Transport and Fate of Polybrominated Diphenyl Ethers in the Baltic and Arctic Regions

Download or read book Transport and Fate of Polybrominated Diphenyl Ethers in the Baltic and Arctic Regions written by Anna Palm and published by Nordic Council of Ministers. This book was released on 2004 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Child specific Exposure Factors Handbook

Download or read book Child specific Exposure Factors Handbook written by and published by . This book was released on 2002 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Emission Patterns and Risk Assessment of Polybrominated Diphenyl Ethers and Bromophenols in Water and Sediments from the Beijiang River  South China

Download or read book Emission Patterns and Risk Assessment of Polybrominated Diphenyl Ethers and Bromophenols in Water and Sediments from the Beijiang River South China written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Toxic Safety

    Book Details:
  • Author : Alissa Cordner
  • Publisher : Columbia University Press
  • Release : 2016-03-29
  • ISBN : 0231541384
  • Pages : 347 pages

Download or read book Toxic Safety written by Alissa Cordner and published by Columbia University Press. This book was released on 2016-03-29 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Initially marketed as a life-saving advancement, flame retardants are now mired in controversy. Some argue that data show the chemicals are unsafe while others continue to support their use. The tactics of each side have far-reaching consequences for how we interpret new scientific discoveries. An experienced environmental sociologist, Alissa Cordner conducts more than a hundred interviews with activists, scientists, regulators, and industry professionals to isolate the social, scientific, economic, and political forces influencing environmental health policy today. Introducing "strategic science translation," she describes how stakeholders use scientific evidence to support nonscientific goals and construct "conceptual risk formulas" to shape risk assessment and the interpretation of empirical evidence. A revelatory text for public-health advocates, Toxic Safety demonstrates that while all parties interested in health issues use science to support their claims, they do not compete on a level playing field and even good intentions can have deleterious effects.

Book Toxicological Risks of Selected Flame Retardant Chemicals

Download or read book Toxicological Risks of Selected Flame Retardant Chemicals written by National Research Council and published by National Academies Press. This book was released on 2000-07-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.

Book Pentabromodiphenyl Ether as a Global POP

Download or read book Pentabromodiphenyl Ether as a Global POP written by Johanna Peltola and published by Nordic Council of Ministers. This book was released on 2001 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Human Biomonitoring for Environmental Chemicals

Download or read book Human Biomonitoring for Environmental Chemicals written by National Research Council and published by National Academies Press. This book was released on 2006-11-30 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomonitoring—a method for measuring amounts of toxic chemicals in human tissues—is a valuable tool for studying potentially harmful environmental chemicals. Biomonitoring data have been used to confirm exposures to chemicals and validate public health policies. For example, population biomonitoring data showing high blood lead concentrations resulted in the U.S. Environmental Protection Agency's (EPA's) regulatory reduction of lead in gasoline; biomonitoring data confirmed a resultant drop in blood lead concentrations. Despite recent advances, the science needed to understand the implications of the biomonitoring data for human health is still in its nascent stages. Use of the data also raises communication and ethical challenges. In response to a congressional request, EPA asked the National Research Council to address those challenges in an independent study. Human Biomonitoring for Environmental Chemicals provides a framework for improving the use of biomonitoring data including developing and using biomarkers (measures of exposure), research to improve the interpretation of data, ways to communicate findings to the public, and a review of ethical issues.

Book Salivary Bioscience

    Book Details:
  • Author : Douglas A. Granger
  • Publisher : Springer Nature
  • Release : 2020-04-07
  • ISBN : 3030357848
  • Pages : 751 pages

Download or read book Salivary Bioscience written by Douglas A. Granger and published by Springer Nature. This book was released on 2020-04-07 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.

Book Handbook of Psychoeducational Assessment

Download or read book Handbook of Psychoeducational Assessment written by and published by Elsevier. This book was released on 2001-04-17 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Psychoeducational Assessment is a practical guide for educational and psychological professionals using norm-referenced tests in the ability, achievement, and behavioral assessment of children. Written by key individuals involved in the construction and evolution of the most widely used tests, this book provides critical information on the nature and scope of commonly used tests, their reliability and validity, administration, scoring and interpretation, and on how the tests may differ and complement each other in their utility with specific populations. Part 1 of the Handbook of Psychoeducational Assessment focuses on ability assessment and the use of full battery intelligence tests as well as brief scales and short forms. Part 2 discusses achievement and the expanded role of psychologists in consultation with educators. Part 3 covers behavior assessment with special attention given to discussion of which tests are most suitable for assessing specific behavioral problems such as ADHD, anxiety, and depression. The final section recognizes the importance of context and person sensitive assessment practices, discussing cross-cultural assessment, neuropsychological assessment, and the usefulness of dynamic assessment for program planning and intervention delivery. Key Features: - Covers the most commonly used and newest assessment instruments - Describes the nature, scope, reliability, and validity of each test - Discusses the administration, scoring, and interpretation of tests - Provides empirical findings on patterns of performance with tested populations - Includes case studies to highlight the utility of specific tests for specific populations - Illustrates new developments in instrumentation and unique features - Covers the most commonly used and newest assessment instruments - Describes the nature, scope, reliability, and validity of each test - Discusses the administration, scoring, and interpretation of tests - Provides empirical findings on patterns of performance with tested populations - Includes case studies to highlight the utility of specific tests for specific populations - Illustrates new developments in instrumentation and unique features