Download or read book Alloimmune Disorders of Pregnancy written by Andrew Hadley and published by Cambridge University Press. This book was released on 2002 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overview of the alloimmune disorders of pregnancy which arise from maternal immunisation to fetal blood cells.
Download or read book Alloimmunization and Role of HLA in Pregnancy written by Meenakshi Singh and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alloimmunization also known as isoimmunization, during pregnancy is the production of IgG antibodies by the mother against the paternally inherited antigens (IPA) in the foetus/newborn. The alloimmunization during pregnancy leads to various alloimmune disorders, such as, haemolytic disease of the foetus and newborn (HDFN), neonatal alloimmune neutropenia (NAN) and foetal and neonatal alloimmune thrombocytopenia (FNAIT) due to the production of maternal alloantibodies against the red blood cell antigen, neutrophils and platelets cell antigens, respectively. Recent studies suggest that maternal anti-HLA class I alloantibodies may also be the cause of FNAIT in addition to antibodies against platelet antigens. On the contrary, studies have also suggested that HLA-C, a classical HLA class I molecule, and HLA-G, a nonclassical HLA molecule, play an important role in placentation and modulation of the maternal immune system during pregnancy, respectively, and thereby leading to acceptance of the semi allogeneic fetus. So far most of the studies have discussed alloimmunization in pregnancy relating to Rh antigen. Thus, in this chapter an attempt has been made to discuss alloimmunization in pregnancy caused because of maternal alloantibody against HLA antigen and its role in immune modulation during pregnancy.
Download or read book The Obstetric Hematology Manual written by Sue Pavord and published by Cambridge University Press. This book was released on 2018-02-08 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.
Download or read book Neonatal Hematology written by Pedro A. de Alarcón and published by Cambridge University Press. This book was released on 2021-02-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
Download or read book Williams Hematology 9E written by Kenneth Kaushansky and published by McGraw Hill Professional. This book was released on 2015-12-23 with total page 2528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2019! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
Download or read book Immunology of Pregnancy written by Udo R. Markert and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the discipline of immunology which studies a unique physiological phenomenon contradicting many of the generally established rules in the field: immunology of pregnancy. It provides a wide overview of the current research of this topic. Prominent and leading international groups contributed by reviewing the most significant findings in the field.
Download or read book Obstetric Care written by Martin Olsen and published by Cambridge University Press. This book was released on 2017-10-04 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain a critical understanding of obstetrics, and a thorough knowledge base of modern management techniques, with this accessible textbook. While acting as a stand-alone text on obstetric care, this volume also forms part of a three-volume set - all authored by leading authorities - on the entirety of obstetric and gynecologic practice. Obstetric Care's topics are based on academic objectives of experts in the field. This textbook offers tailored support for new residents and experienced physicians alike. Obstetric Care is invaluable for wide-ranging yet concise reference material, and provides evidence based care recommendations for specific patient conditions. The chapters in this textbook are based on the objectives of the Committee for Resident Education in Obstetrics and Gynecology; the book offers outstanding modern management techniques across the obstetrics specialty, making it a go-to for reference and comprehensive study.
Download or read book Chesley s Hypertensive Disorders in Pregnancy written by Robert N. Taylor and published by Elsevier. This book was released on 2014-08-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chesley’s Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. The fourth edition of Chesley’s Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia. Features new chapters focusing on recent discoveries in areas such as fetal programming, genomics/proteomics, and angiogenesis Includes extensive updates to chapters on epidemiology, etiological considerations, pathophysiology, prediction, prevention, and management Discusses the emerging roles of metabolic syndrome and obesity and the increasing incidence of preeclampsia Each section overseen by one of the editors; each chapter co-authored by one of the editors, ensuring coherence throughout book
Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunological Molecular and Proteomic Evaluation of Pregnancy Associated Conditions Using Human Placental Models written by Charlene Porter and published by . This book was released on 2011 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eleven differentially expressed protein species were identified when comparing different STBM samples. Future work aims to compare the normal placental proteome with the proteome of placentas from complicated pregnancies (e.g. PE, IUGR, PTL and Trisomies 13, 18 and 21) to discover potential biomarkers for screening.
Download or read book Fetal Medicine written by Bidyut Kumar and published by Cambridge University Press. This book was released on 2016-04-07 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the RCOG Training Module in Fetal Medicine, this book provides a knowledge base for practitioners in obstetrics and maternal-fetal medicine.
Download or read book Antenatal Disorders for the MRCOG and Beyond written by Dilly Anumba and published by Cambridge University Press. This book was released on 2016-08-18 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully up to date, this new edition covers all aspects of care for women developing disorders during pregnancy.
Download or read book Placental and Gestational Pathology with Online Resource written by Raymond W. Redline and published by Cambridge University Press. This book was released on 2018-08-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.
Download or read book Guidelines for Prenatal and Perinatal Immunohematology written by W. John Judd and published by A A B B Press. This book was released on 2005-01-01 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Autoimmune Diseases in Pregnancy written by and published by . This book was released on 2014 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background : Autoimmune (AI) diseases unlike most other chronic diseases in pregnancy have been understudied. The objectives of this dissertation were to evaluate the impact of AI disease severity on pregnancy outcomes, to examine how AI diseases affect the relationship between a common comorbid condition, nausea and vomiting in pregnancy (NVP), and spontaneous abortion (SAB), and lastly to explore missingness of HC in pregnant women with and without AI diseases. Methods : Secondary analyses were carried out on data collected prospectively in the OTIS Autoimmune Diseases in Pregnancy Project between 2004 and 2011. Analyses were carried out on different subsets of the main study to: (1) examine the relationship between rheumatoid arthritis (RA) disease severity measured during early pregnancy and selected pregnancy outcomes, (2) assess impact of maternal AI status on the occurrence of NVP and examine how NVP in these women is related to differential risk of SAB, and (3) examine a methodological issue on patterns and factors associated with missing exposure variables relevant to pregnancy cohort studies such as the OTIS Autoimmune Diseases in Pregnancy Project : whether "missingness" of head circumference (HC) measurement at birth in this dataset occurred completely at random or is systematically biased in ways that might compromise the validity of interpretation. Results: After adjusting for covariates, RA disease severity in early pregnancy was predictive of increased risk for preterm delivery in women with AI disease (aRR=1.55, 95% CI: 1.17, 2.07). Overall adjusted HR for NVP and SAB was 0.65 (95% CI: 0.29, 1.48). AI disease status did not affect the association between NVP and SAB. Adjusting for covariates, non-availability of medical records was strongly associated with missing HC. Conclusion : Disease severity in early pregnancy in women with RA is predictive of preterm delivery. There was no differential association between NVP and SAB in women with AI diseases. Finally, missing medical records was significantly associated with missing HC and we need to be cautious when interpreting results with missing covariates especially when the rate of missingness is not mentioned.
Download or read book Immunology of Recurrent Pregnancy Loss and Implantation Failure written by Joanna Kwak-Kim and published by Elsevier. This book was released on 2022-07-07 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure
Download or read book Clinical Maternal Fetal Medicine written by Hung N. Winn and published by CRC Press. This book was released on 2021-09-01 with total page 855 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive, one-stop online book relating to all areas of pregnancy and birth. The second edition of this easily searchable guide is edited by eminent experts in the field and includes new contributions from international authors. It will be an ideal reference for Maternal-Fetal Specialists and Generalists wanting an authoritative answer on any point. Key features: •Grouped in to six topics (modules) for convenience •Electronic search facility across all chapters •Approximately 700,000 words of text, 7000 references, 300 figures (including 100 in full colour), and 200 tables available to search Key topics: •All common pregnancy and birth related problems such as diabetes and pregnancy •Many rarer complications such as protozoan infections •Fetal assessment, which is absolutely central to MFM practice •Medico-legal aspects •Sickle cell disease – a major problem for patients of African descent New chapters include: •Recurrent early pregnancy losses •Invasive hemodynamic monitoring •Chronic and acute hypertension •Neurological disorders •Maternal obesity •Assessment of fetal genetic disorders •First and second trimester screening
