Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Mathematical Epidemiology written by Fred Brauer and published by Springer Science & Business Media. This book was released on 2008-04-30 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).

Download or read book AIDS Pathogenesis written by H. Schuitemaker and published by Springer Science & Business Media. This book was released on 2000-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Download or read book Mathematical Approaches to Problems in Resource Management and Epidemiology written by Carlos Castillo-Chávez and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book RethinkHIV written by Bjørn Lomborg and published by Cambridge University Press. This book was released on 2012-10-18 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely thought-provoking book, which examines the first-ever comparative cost-benefit analysis of responses to HIV/AIDS in Africa.

Download or read book Stochastic Modeling of AIDS Epidemiology and HIV Pathogenesis written by W. Y. Tan and published by World Scientific. This book was released on 2000 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses systematically treatment on the development of stochastic, statistical and state space models of the HIV epidemic and of HIV pathogenesis in HIV-infected individuals, and presents the applications of these models. The book is unique in several ways: (1) it uses stochastic difference and differential equations to present the stochastic models of the HIV epidemic and HIV pathogenesis; in this sense, the deterministic models are considered as special cases when the numbers of different type of people or cells are very large (2) it provides, a critical analysis of deterministic and statistical models in the literature; (3) it develops state space models by combining stochastic models and statistical models; and (4) it provides a detailed discussion on the pros and cons of the different modeling approaches. This book is the first to introduce state space models for the HIV epidemic. It is also the first to develop stochastic models and state space models for the HIV pathogenesis in HIV-infected individuals.

Download or read book AIDS Bibliography written by and published by . This book was released on 1995-08 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Confronting AIDS written by Institute of Medicine and published by National Academies Press. This book was released on 1988-02-01 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: How far have we come in the fight against AIDS since the Institute of Medicine released Confronting AIDS: Directions for Public Health, Health Care, and Research in 1986? This updated volume examines our progress in implementing the recommendations set forth in the first book. It also highlights new information and events that have given rise to the need for new directions in responding to this disease.

Download or read book Preventing HIV Transmission written by National Research Council and Institute of Medicine and published by National Academies Press. This book was released on 1995-09-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses the interface of two major national problems: the epidemic of HIV-AIDS and the widespread use of illegal injection drugs. Should communities have the option of giving drug users sterile needles or bleach for cleaning needs in order to reduce the spread of HIV? Does needle distribution worsen the drug problem, as opponents of such programs argue? Do they reduce the spread of other serious diseases, such as hepatitis? Do they result in more used needles being carelessly discarded in the community? The panel takes a critical look at the available data on needle exchange and bleach distribution programs, reaches conclusions about their efficacy, and offers concrete recommendations for public policy to reduce the spread of HIV/AIDS. The book includes current knowledge about the epidemiologies of HIV/AIDS and injection drug use; characteristics of needle exchange and bleach distribution programs and views on those programs from diverse community groups; and a discussion of laws designed to control possession of needles, their impact on needle sharing among injection drug users, and their implications for needle exchange programs.

Download or read book A Biologist s Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

Download or read book Epidemic Modelling written by D. J. Daley and published by Cambridge University Press. This book was released on 1999-04-13 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a general introduction to the mathematical modelling of diseases.

Download or read book HIV AIDS A Very Short Introduction written by Alan Whiteside and published by Oxford University Press, USA. This book was released on 2008-01-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an introduction to HIV/AIDS, this book explains the science, the international and local politics, the demographics and the devastating consequences of the disease. This book is aimed at general readers interested in the science, the epidemiology and the social effects of the disease which has killed 20 million.

Download or read book Mathematical and Statistical Approaches to AIDS Epidemiology written by Carlos Castillo-Chavez and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 18 research articles of this volume discuss the major themes that have emerged from mathematical and statistical research in the epidemiology of HIV. The opening paper reviews important recent contributions. Five sections follow: Statistical Methodology and Forecasting, Infectivity and the HIV, Heterogeneity and HIV Transmission Dynamics, Social Dynamics and AIDS, and The Immune System and The HIV. In each, leading experts in AIDS epidemiology present the recent results. Some address the role of variable infectivity, heterogeneous mixing, and long periods of infectiousness in the dynamics of HIV; others concentrate on parameter estimation and short-term forecasting. The last section looks at the interaction between the HIV and the immune system.

Download or read book Economic Aspects of AIDS and HIV Infection written by Detlef Schwefel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the early days of its recognized occurrence, AIDS has been per ceived as posing tremendous threats, burdens and challenges to human beings. Individuals, societies and, in a global point of view, mankind are affected by the effects of the HN infection, the nature and extent of which is still unclear in many ways. In the beginning only biomedical and epidemiological analyses of the problem were the top research priori ties, the former laden with great hopes that it may soon be possible to stop the spread of the disease and to overcome its physical impact. Yet it soon became clear that AIDS would be something to be reckoned and coped with on a long-term basis, making a thorough investigation of its impact absolutely mandatory. AIDS has serious economic consequences. Taken seriously, they can not be confined to predictions of costs intended to support the AIDS issue in the struggle for resources. Besides cost calculations - a method ologically tricky and wide-ranging topic in itself -and their application to cost-effectiveness and other analyses, economic issues include identify ing and assessing patterns of care, analyzing problems of financing, exploring impacts on markets other than health care, and modelling scenarios for future developments and strategies. At present, the eco nomic aspects of AIDS still constitute a very recent topic in European health economics and health systems research. Many projects are just about to start, and there must be a better exchange of information between research groups.

Download or read book Sexually Transmitted Infections written by National Academies of Sciences, Engineering, and Medicine and published by . This book was released on 2021-12-24 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: One in five people in the United States had a sexually transmitted infection (STI) on any given day in 2018, totaling nearly 68 million estimated infections. STIs are often asymptomatic (especially in women) and are therefore often undiagnosed and unreported. Untreated STIs can have severe health consequences, including chronic pelvic pain, infertility, miscarriage or newborn death, and increased risk of HIV infection, genital and oral cancers, neurological and rheumatological effects. In light of this, the Centers for Disease Control and Prevention, through the National Association of County and City Health Officials, commissioned the National Academies of Sciences, Engineering, and Medicine to convene a committee to examine the prevention and control of sexually transmitted infections in the United States and provide recommendations for action. In 1997, the Institute of Medicine released a report, The Hidden Epidemic: Confronting Sexually Transmitted Diseases. Although significant scientific advances have been made since that time, many of the problems and barriers described in that report persist today; STIs remain an underfunded and comparatively neglected field of public health practice and research. The committee reviewed the current state of STIs in the United States, and the resulting report, Sexually Transmitted Infections: Advancing a Sexual Health Paradigm, provides advice on future public health programs, policy, and research.

Download or read book Frontiers in Mathematical Biology written by Simon A. Levin and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a mathematical point of view, physiologically structured population models are an underdeveloped branch of the theory of infinite dimensional dynamical systems. We have called attention to four aspects: (i) A choice has to be made about the kind of equations one extracts from the predominantly verbal arguments about the basic assumptions, and subsequently uses as a starting point for a rigorous mathematical analysis. Though differential equations are easy to formulate (different mechanisms don't interact in infinites imal time intervals and so end up as separate terms in the equations) they may be hard to interpret rigorously as infinitesimal generators. Integral equations constitute an attractive alternative. (ii) The ability of physiologically structured population models to increase our un derstanding of the relation between mechanisms at the i-level and phenomena at the p-level will depend strongly on the development of dynamical systems lab facilities which are applicable to this class of models. (iii) Physiologically structured population models are ideally suited for the for mulation of evolutionary questions. Apart from the special case of age (see Charlesworth 1980, Yodzis 1989, Caswell 1989, and the references given there) hardly any theory exists at the moment. This will, hopefully, change rapidly in the coming years. Again the development of appropriate software may turn out to be crucial.

Download or read book Modeling HIV Transmission and AIDS in the United States written by Herbert W. Hethcote and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disease that came to be called acquired immunodeficiency syndrome (AIDS) was first identified in the summer of 1981. By that time, nearly 100,000 persons in the United States may have been infected with human immunodeficiency virus (HIV). By the time the routes of transmission were clearly identified and HIV was established as the cause of AIDS in 1983, over 300,000 people may have been infected. That number has continued to increase, with approximately 1,000,000 Americans believed to be infected in 1991. The epidemic is of great public health concern because HlV is infectious, causes severe morbidity and death in most if not all of those infected, and often occurs in relatively young persons. In addition, the cost of medical care for a person with HIV disease is high, and the medical care needs of HIV-infected persons place a severe burden on the medical care systems in many areas. Understanding and controlling the HIV epidemic is a particularly difficult challenge. The long and variable period between HIV infection and clinical disease makes it difficult both to forecast the future magnitude of the epidemic, which is important for health care planning, and to estimate the number infected in the last several years, which is important for monitoring the current status of the epidemic.