Download or read book A Model of Scintillation Detector Performance for Positron Emission Tomography written by Suleman Surti and published by . This book was released on 2000 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of a Scintillation Detector and the Influence on Clinical Imaging written by Joseph Vincent Panetta and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detector is the functional unit within a Positron Emission Tomography (PET) scanner, serving to convert the energy of radiation emitted from a patient into positional information, and as such contributes significantly to the performance of the scanner. Excellent spatial resolution in continuous detectors that are thick has proven difficult to achieve using simple positioning algorithms, leading to research in the field to improve performance. This thesis aims to investigate the effect of modifications to the scintillation light spread within the bulk of the scintillator to improve performance, focusing on the use of laser induced optical barriers (LIOBs) etched within thick continuous crystals, and furthermore aims to translate the effect on detector performance to scanner quantitation in patient studies. The conventional continuous detector is first investigated by analyzing the various components of the detector as well as its limitations. It is seen that the performance of the detector is affected by a number of variables that either cannot be improved or may be improved only at the expense of greater complexity or computing time; these include the photodetector, the positioning algorithm, and Compton scatter in the detector. The performance of the detectors, however, is fundamentally determined by the light spread within the detector, and limited by the depth-dependence of the light spread and poor performance in the entrance region, motivating efforts to modify this aspect of the detector. The feasibility and potential of LIOBs to fine-tune this light spread and improve these limitations is then studied using both experiments and simulations. The behavior of the LIOBs in response to optical light is investigated, and the opacity of the etchings is shown to be dependent on the parameters of the etching procedure. Thick crystals were also etched with LIOBs in their entrance region in a grid pattern in order to improve the resolution in the entrance region. Measurements show an overall improvement in spatial resolution: the resolution in the etched region of the crystals is slightly improved (e.g., ~0.8mm for a 25mm thick crystal), though in the unetched region, it is slightly degraded (e.g., ~0.4mm for a 25mm thick crystal). While the depth-dependence of the response of the crystal is decreased, the depth-of-interaction (DOI) performance is degraded as well. Simulation studies informed by these measurements show that the properties of the LIOBs strongly affect the performance of the crystal, and ultimately further illustrate that trade-offs in spatial resolution, position sampling, and DOI resolution are inherent in varying the light spread using LIOBs in this manner; these may be used as a guide for future experiments. System Monte Carlo simulations were used to investigate the added benefit of improved detector spatial resolution and position sampling to the imaging performance of a whole-body scanner. These simulations compared the performance of scanners composed of conventional pixelated detectors to that of scanners using continuous crystals. Results showed that the improved performance (relative to that of 4-mm pixelated detectors) of continuous crystals with a 2-mm resolution, pertinent to both the etched 14mm thick crystal studied as well as potential designs with the etched 25mm thick crystal, increased the mean contrast recovery coefficient (CRC) of images by ~22% for 5.5mm spheres. Last, a set of experiments aimed to test the correspondence between quantification in phantom and patient images using a lesion embedding methodology, so that any improvements determined using phantom studies may be understood clinically. The results show that the average CRC values for lesions embedded in the lung and liver agree well with those for lesions embedded in the phantom for all lesion sizes. In addition, the relative changes in CRC resulting from application of post-filters on the subject and phantom images are consistent within measurement uncertainty. This study shows that the improvements in CRC resulting from improved spatial resolution, measured using phantom studies in the simulations, are representative of improvements in quantitative accuracy in patient studies. While unmodified thick continuous detectors hold promise for both improved image quality and quantitation in whole-body imaging, excellent performance requires intensive hardware and computational solutions. Laser induced optical barriers offer the ability to modify the light spread within the scintillator to improve the intrinsic performance of the detector: while measurements with crystals etched with relatively transmissive etchings show a slight improvement in resolution, simulations show that the LIOBs may be fine-tuned to result in improved performance using relatively simple positioning algorithms. For systems in which DOI information is less important, and transverse resolution and sensitivity are paramount, etching thick detectors with this design, fine-tuned to the particular thickness of the crystal and application, is an interesting alternative to the standard detector design.
Download or read book Modelling Monolithic Scintillator Detectors for Positron Emission Tomography written by Dingeman Jan Van Der Laan and published by Delft University Press. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume investigates the use, design and modelling of monolithic scintillation detectors as an alternative for high resolution Positron Emission Tomography (PET). Many detectors currently used for high resolution PET utilize scintillating crystals coupled to photo-multiplier tubes. But such detectors tend not to be sufficiently sensitive, neither do they correct for depth of interaction. Monolithic scintillation detectors offer a promising alternative which overcomes these problems. They potentially have both a higher sensitivity and improved resolution. This work examines the performance of such detectors and seeks to attain a qualitative and quantitative understanding of the relationship between the properties shape, dimensions, materials used etc.
Download or read book The High Countrate Performance of Positron Emission Tomography Systems Using Continuous Position sensitive Scintillation Detectors written by David A. Mankoff and published by . This book was released on 1988 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monolithic Scintillator Detectors for High resolution Positron Emission Tomography written by Marnix Christiaan Maas and published by Pro Universitate. This book was released on 2008 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NATO Advances Research Workshop (ARW) 'Secure Telematic Applications for National Scale Projects' is organized in the frame of the National Week of Information Technologies and Sixth International Congress 'Scientific and Methodological Facilitation of the Development of Informatization and the System of Scientific and Technical Information in the Republic of Belarus. Secure Telematic Applications in National and International Projects'. The participants of the event came to Minsk from all regions of Europe, as well as from Asia and Africa. Besides the general ARW topic, the participants also discussed the progress in the activity of the High Technologies Park, the creation of the corporate network of libraries of Belarus on the basis of the National Library of Belarus and the newest technologies of e-government. The presentations are also oriented on creation of the National Scientific and Research Computer Network of the Republic of Belarus on the basis of Academic Network BASNET. It is expected that the scientific and practical achievements of the forum will considerably influence both the development of the information technologies and their utilization for advantage of the national economy of Belarus and all participating countries.
Download or read book Radiation Detectors for Medical Applications written by Stefaan Tavernier and published by Springer Science & Business Media. This book was released on 2006-10-02 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of this book is the use of scintillating materials in the detection of ionising radiation for medical imaging. The text surveys the state of the art in radiation detectors for medical imaging, followed by an in-depth review of all aspects of the use of scintillating materials. Also included are detailed discussion of ways to improve the performance of existing scintillating materials and completely novel uses of scintillating materials.
Download or read book High Efficiency Low Cost Scintillators for PET written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic scintillation detectors coupled to PMTs are an important element of medical imaging applications such as positron emission tomography (PET). Performance as well as cost of these systems is limited by the properties of the scintillation detectors available at present. The Phase I project was aimed at demonstrating the feasibility of producing high performance scintillators using a low cost fabrication approach. Samples of these scintillators were produced and their performance was evaluated. Overall, the Phase I effort was very successful. The Phase II project will be aimed at advancing the new scintillation technology for PET. Large samples of the new scintillators will be produced and their performance will be evaluated. PET modules based on the new scintillators will also be built and characterized.
Download or read book Nuclear Medicine Instrumentation written by Jennifer Prekeges and published by Jones & Bartlett Publishers. This book was released on 2013 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Written at the technologist level, Nuclear Medicine Instrumentation, Second Edition focuses on instruments essential to the practice of nuclear medicine. Covering everything from Geiger counters to positron emission tomography systems, this text provides students with an understanding of the practical aspects of these instruments and their uses in nuclear medicine. Nuclear Medicine Instrumentation is made up of four parts: Small Instruments Gamma Camera Single Photon Emission Computed Tomography (SPECT) Positron Emission Tomography (PET) By concentrating on the operation of these instruments and the potential pitfalls that they are subject to, students will be better prepared for what they may encounter during their career. The Second Edition includes revised content and updated data throughout as well as a new chapter on Magnetic Resonance Imaging and Its Application to Nuclear Medicine and a new Appendix on Laboratory Accreditation"--
Download or read book Positron Emission Particle Tracking written by Kit Windows-Yule and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Study of Inter Detector Scattering and Enhancement of Detector Performance in a Positron Emission Tomography System written by Saeed Sarkar and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy written by Yuji Kuge and published by Springer. This book was released on 2016-04-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.
Download or read book Nuclear Medicine Instrumentation written by and published by Jones & Bartlett Publishers. This book was released on with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Oncology written by H. William Strauss and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
Download or read book PET written by Michael E. Phelps and published by Springer Science & Business Media. This book was released on 2006-12-30 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to give the reader a solid understanding of the physics and instrumentation aspects of PET, including how PET data are collected and formed into an image. Topics include basic physics, detector technology used in modern PET scanners, data acquisition, and 3D reconstruction. A variety of modern PET imaging systems are also discussed, including those designed for clinical services and research, as well as small-animal imaging. Methods for evaluating the performance of these systems are also outlined. The book will interest nuclear medicine students, nuclear medicine physicians, and technologists.
Download or read book Positron Emission Tomography written by Dale L. Bailey and published by Springer Science & Business Media. This book was released on 2006-07-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)
Download or read book Energy Research Abstracts written by and published by . This book was released on 1995 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigation of Timing Performance of Scintillation Detectors for Time of Flight PET written by Rony Izack Wiener and published by . This book was released on 2013 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
