Download or read book A Better Faster Road from Biological Data to Human Health written by Brian Hawkins and published by . This book was released on 2017 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A better faster road from biological data to human health written by Brian Hawkins and published by RTI Press. This book was released on 2017-06-11 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, the interactions of drugs and toxicants with human tissue have been investigated in a reductionist way—for example, by focusing on specific molecular targets and using single-cell-type cultures before testing compounds in whole organisms. More recently, “systems biology” approaches attempt to enhance the predictive value of in vitro biological data by adopting a comprehensive description of biological systems and using computational tools that are sophisticated enough to handle the complexity of these systems. However, the utility of computational models resulting from these efforts completely relies on the quality of the data used to construct them. Here, we propose that recent advances in the development of bioengineered, three-dimensional, multicellular constructs provide in vitro data of sufficient complexity and physiological relevance to be used in predictive systems biology models of human responses. Such predictive models are essential to maximally leveraging these emerging bioengineering technologies to improve both therapeutic development and toxicity risk assessment. This brief outlines the opportunities presented by emerging technologies and approaches for the acceleration of drug development and toxicity testing, as well as the challenges lying ahead for the field.
Download or read book The Kefir Solution written by Shann Nix Jones and published by Hay House, Inc. This book was released on 2018-06-26 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Irritable Bowel Syndrome is the most common gastrointestinal disorder in the world. People with IBS are prescribed more medications, miss more work days, have lower work productivity and higher suicide rates than people without it. Yet the causes are still unknown, and there is no cure. Or rather – there was no cure, until now.Cutting-edge scientific research has found that IBS is nearly always connected to anxiety and depression through something called the gut-brain axis. Heal the gut and you can heal the brain – and vice versa.Enter The Kefir Solution. Developed by Shann Nix Jones, it uses kefir, a powerful natural probiotic to support your microbiome and help heal IBS without the use of chemicals. It has no nasty side effects but loads of health benefits – including alleviating the anxiety and depression that often go hand in hand with IBS. Combining common sense with uncommon science, Shann shares stories, tips and recipes to help you on your way to better gut health and a happier life.If you suffer from IBS, or know someone who does, and it’s taken hold of your life, this book could lead you back to health and freedom.
Download or read book General Science Technology Quick Revision Material for UPSC State PSC General Studies Exams written by Disha Experts and published by Disha Publications. This book was released on 2021-08-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Networks in Human Health and Disease written by Romana Ishrat and published by Springer Nature. This book was released on 2023-10-13 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents methods and tools of network biology and bioinformatics for understanding the disease dynamics and identification of drug targets. The initial section of chapters introduce the theoretical aspects followed by the different applications for construction and analysis of biological networks, methods for identifying crucial nodes in networks, and network dynamics. The book covers the latest advances in the network medicine, exploring the different types of biological networks, and their applications. It further reviews the role of R language in the network-based approaches that help in understanding biological systems and identifying biological functions. Towards the end, the book explores the recent developments and applications in machine learning and its potential for advancing network biology. Finally, the book elucidates a comprehensive yet a representative description of challenges associated with the understanding of disease dynamics using network biology. Given its scope, the book is intended for researchers and advanced postgraduate students of bioinformatics, computational biology, and medical sciences.
Download or read book New Technologies for Toxicity Testing written by Michael Balls and published by Springer Science & Business Media. This book was released on 2012-03-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Of course, many of the techniques and methods described in this volume are in the early stages of development, and much work will be needed to ensure their further improvement, optimisation and validation. However, we are confident that this will be achieved and that, just as with the in vitro assays that were validated and granted regulatory acceptance over the last decade, these, and many other new, advanced methods, will likewise become part of the toxicologist’s improved toolbox for coping with increasingly stringent and numerous regulatory requirements and test chemicals, while placing less reliance on traditional testing paradigms.
Download or read book Men s Health written by and published by . This book was released on 2006-05 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Men's Health magazine contains daily tips and articles on fitness, nutrition, relationships, sex, career and lifestyle.
Download or read book Hybrid Healthcare written by Mussaad Al-Razouki and published by Springer Nature. This book was released on 2022-07-22 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential book reviews how digital health ventures can be integrated with more traditional techniques to revolutionize the healthcare system. Details of the current state of the digital marketplace, the available tools for early detection and diagnostics that presently employ digital technologies are provided. Relevant aspects of blockchain, artificial intelligence including data lake development and data analytics are described. The role of regulators and legislation including GDPR are also covered. Hybrid Healthcare provides a thorough overview of how digital health entrepreneurs will need to employ a hybrid approach to address many healthcare challenges of the 21st century. It is therefore an indispensable resource for all those seeking to develop their knowledge of this rapidly growing sector.
Download or read book Knowledge Based Bioinformatics written by Gil Alterovitz and published by John Wiley & Sons. This book was released on 2011-04-20 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology. Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions. Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics. Written by leading international experts in this field. Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.
Download or read book Machine Learning and Systems Biology in Genomics and Health written by Shailza Singh and published by Springer Nature. This book was released on 2022-02-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. It discusses how systems biology is exploited in identifying the genetic markers for drug discovery and disease identification. Myriad number of diseases whether be infectious, metabolic, cancer can be dealt in effectively which combines the different omics data for precision medicine. Major breakthroughs in the field would help reflect more new innovations which are at their pinnacle stage. This book is useful for researchers in the fields of genomics, genetics, computational biology and bioinformatics.
Download or read book Human Biology written by Daniel Chiras and published by Jones & Bartlett Learning. This book was released on 2012 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for the introductory human biology course, the Seventh Edition of Chiras' acclaimed text maintains the original organizational theme of homeostasis presented in previous editions to present the fundamental concepts of mammalian biology and human structure and function. Chiras discusses the scientific process in a thought-provoking way that asks students to become deeper, more critical thinkers. The focus on health and homeostasis allows students to learn key concepts while also assessing their own health needs. An updated and enhanced ancillary package includes numerous student and instructor tools to help students get the most out of their course!
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Download or read book Intervention Research and Evidence Based Quality Improvement Second Edition written by Bernadette Mazurek Melnyk, PhD, APRN-CNP, FAANP, FNAP, FAAN and published by Springer Publishing Company. This book was released on 2018-08-28 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Edition received 2012 First Place AJN Book of the Year Award in Nursing Research! “This is a resource for success and should be a part of any researcher's library." --Doody's Medical Reviews (Praise for the First Edition) Written for researchers, clinicians and doctoral students, the newly revised edition of this comprehensive reference continues to deliver the essentials of intervention research with added content on evidence-based quality improvement, a must for improving healthcare quality, safety and population health outcomes. Although typically it takes years for research-based interventions to make their way to real world clinical settings, this “prolonged time for translation” frustrates researchers and their interprofessional teams. This second edition now delves even deeper into key strategies for rapidly moving research-based interventions into real world settings in the form of evidence-based quality improvement as well as the challenges of working in an increasingly diverse professional research environment. Intervention Research and Evidence-Based Quality Improvement, Second Edition begins at the pilot study phase for intervention research and highlights every step of the way through to full-scale randomized controlled trials. Written in user-friendly format, content covers designing, conducting, analyzing, and funding intervention studies that improve healthcare quality and people’s health outcomes. Chapters cover writing grant applications and show examples of actual applications that have been funded by NIH and other organizations. These real-life samples are available online, alongside additional progress reports and final reports. Real-world examples of evidence-based quality improvement projects that have improved outcomes also are highlighted in this second edition. New to the Second Edition: Describes evidence-based quality improvement and specific steps in conducting EBQI projects, which are essential for enhancing healthcare quality, safety and costs along with enhancing population health outcomes. Emphasizes the importance of interprofessional teams Focuses on using research-based interventions in real-world settings Six new chapters o Generating Versus Using Evidence to Guide Best Practice o Setting the Stage for Intervention Research and Evidence-based Quality Improvement o Evidence-based Quality Improvement o Translational Research: Why and How o Factors Influencing Successful Uptake of Evidence-Based Interventions in Clinical Practice o Using Social Media to Enhance Uptake of Research-Based Interventions into Real World Clinical Settings Key Features: Provides a practical, comprehensive resource for designing, conducting, analyzing, and funding intervention studies Outlines the specific steps in designing, conducting and evaluating outcomes of evidence-based quality improvement projects Includes examples of funding research grants, progress reports, and final reports Serves as a core text for students in doctoral nursing and other health sciences programs
Download or read book A Biologist s Guide to Artificial Intelligence written by Ambreen Hamadani and published by Elsevier. This book was released on 2024-03-15 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Biologist’s Guide to Artificial Intelligence: Building the Foundations of Artificial Intelligence and Machine Learning for Achieving Advancements in Life Sciences provides an overview of the basics of Artificial Intelligence for life science biologists. In 14 chapters/sections, readers will find an introduction to Artificial Intelligence from a biologist’s perspective, including coverage of AI in precision medicine, disease detection, and drug development. The book also gives insights into the AI techniques used in biology and the applications of AI in food, and in environmental, evolutionary, agricultural, and bioinformatic sciences. Final chapters cover ethical issues surrounding AI and the impact of AI on the future. This book covers an interdisciplinary area and is therefore is an important subject matter resource and reference for researchers in biology and students pursuing their degrees in all areas of Life Sciences. It is also a useful title for the industry sector and computer scientists who would gain a better understanding of the needs and requirements of biological sciences and thus better tune the algorithms. Helps biologists succeed in understanding the concepts of Artificial Intelligence and machine learning Equips with new data mining strategies an easy interface into the world of Artificial Intelligence Enables researchers to enhance their own sphere of researching Artificial Intelligence
Download or read book Review of the Liquid Metal Fast Breeder Program written by United States. Congress. Joint Committee on Atomic Energy. Ad Hoc Subcommittee to Review the Liquid Metal Fast Breeder Reactor Program and published by . This book was released on 1975 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Reconstruction of Missing Data in Biological Research written by Feng Bao and published by Springer Nature. This book was released on 2021-08-06 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging biotechnologies have significantly advanced the study of biological mechanisms. However, biological data usually contain a great amount of missing information, e.g. missing features, missing labels or missing samples, which greatly limits the extensive usage of the data. In this book, we introduce different types of biological data missing scenarios and propose machine learning models to improve the data analysis, including deep recurrent neural network recovery for feature missings, robust information theoretic learning for label missings and structure-aware rebalancing for minor sample missings. Models in the book cover the fields of imbalance learning, deep learning, recurrent neural network and statistical inference, providing a wide range of references of the integration between artificial intelligence and biology. With simulated and biological datasets, we apply approaches to a variety of biological tasks, including single-cell characterization, genome-wide association studies, medical image segmentations, and quantify the performances in a number of successful metrics. The outline of this book is as follows. In Chapter 2, we introduce the statistical recovery of missing data features; in Chapter 3, we introduce the statistical recovery of missing labels; in Chapter 4, we introduce the statistical recovery of missing data sample information; finally, in Chapter 5, we summarize the full text and outlook future directions. This book can be used as references for researchers in computational biology, bioinformatics and biostatistics. Readers are expected to have basic knowledge of statistics and machine learning.
Download or read book SAB Report Future Methods and Issues written by United States. Environmental Futures Committee and published by . This book was released on 1995 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
