Download or read book Synthetic Approaches to Zizanoic Acid written by Steven E. Brown and published by . This book was released on 1984 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Total Synthesis of Natural Products written by Michael C. Pirrung and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past two decades have seen an explosion in research on the synthesis of sesquiterpenes, an important class of hydrocarbons commonly found in oils, resins, and balsams. Volume Eleven in The Total Synthesis of Natural Products series continues to review this dynamic area of chemistry. It features systematic, A-to-Z coverage of sesquiterpenes synthesized between 1979-1994-a sesquidecade. Focusing on bicyclic and tricyclic compounds in sesquiterpene synthesis, this authoritative work complements Volume Ten's coverage of acyclic and monocyclic sesquiterpenes. The authors comb through the hundreds of sesquiterpene syntheses already developed, consolidating the multitude of research papers, and providing extensive references as well as author and subject indexes. To keep the presentation manageable, they emphasize literature where natural products were prepared, leaving out natural ring systems or compounds whose structures were misassigned. This volume presents multiple syntheses of the same compound in chronological order, making the various steps of the synthetic strategy easily accessible. In addition, it addresses one of the most important developments in sesquiterpene research, namely the increase in compound targets prepared in an optically active form. And while syntheses of racemates are not specifically marked, legends for synthesis schemes producing optically active compounds include their absolute configurations, signs of optical rotation, or both. An important resource for organic chemists, pharmaceutical and medicinal chemists, natural prod-ucts chemists, and biochemists, The Total Synthesis of Natural Products offers valuable insight into the structure and makeup of sesquiterpenes while serving as a practical tool for locating any of the major classes of sesquiterpene compounds. An invaluable guide for the chemist interested in natural products. Providing a fascinating, comprehensive look at sesquiterpene synthesis, Volume Eleven of The Total Synthesis of Natural Products reviews sesquiterpenes synthesized in the period 1979-1994, continuing the coverage begun with Volume Ten in the series (see below). This authoritative work: Focuses on bicyclic and tricyclic sesquiterpenes. Explains the structure and makeup of this important class of hydrocarbons. Serves as a useful, practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds. Provides multiple syntheses of the same compound chronologically, clearly showing the evolution of the synthetic strategy. Also available . . .THE TOTAL SYNTHESIS OF NATURAL PRODUCTS Volume Ten, Edited by David Goldsmith. A complement to this work, Volume Ten examines compounds with acyclic and monocyclic ring structures in sesquiterpene synthesis. 1997 (0-471-59679-5) 173 pp.
Download or read book Studies Directed Toward a Synthesis of the Sesquiterpene Zizanoic Acid written by Frank W. B. Skinner and published by . This book was released on 1976 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Part 1 Total Synthesis of khusimone zizanoic Acid and epizizanoic Acid written by Hong Chan Wing and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this thesis describes a total synthesis of three zizaene sesquiterpenes, (-)-khusimone (I), (-)-epizizanoic acid (II) and (t)-zizanoic acid (III), starting from the coirmer- cially available (-) -J-l 0-camphor sulfonic acid ammonium salt (IV). Fusion of the salt IV with solid potassium hydroxide gave (-) - a -campholenic acid (V) which was converted to the corresponding methyl ester VI with methyl iodide and potassium carbonate in refluxing acetone. Ozonolysis of ester VI followed by reductive work-up using triphenylphosphine afforded keto aldehyde VII. Its cyclization to enone VIII was effected by p-toluenesulfonic acid in refluxing benzene. Irradiation of enone VIII with 1,1-diethoxy- ethene followed by hydrolysis of the photoadduct IX gave rise to a mixture of diketones X and XI in a ratio of 5:8. The latter product was converted to the former one by treatment with pyridin- ium bromide perbromide in acetic acid followed by reduction of the resulting enediones XII with zinc in acetic acid. Selective ketalization of diketone X using 2-ethyl-2-methyl- 1,3-dioxolane and p-toluenesulfonic acid gave rise to ketal XIII which was hydrolyzed to the corresponding acid XIV with alkali. Treatment of the sodium salt derived from acid XIV and sodium hydride with methyl magnesium bromide followed by esterification of the resulting hydroxy acid XV with diazomethane afforded alcohol XVI. On treatment with thionyl chloride in pyridine in benzene, alcohol XVI underwent dehydration to give ester XVII which was subsequently reduced by lithium aluminium hydride to alcohol XVIII. Its conversion to the corresponding chloride XIX was effected by phosphorus oxychloride in pyridine. Hydrolysis of chloride XIX with hydrochloric acid and ring expansion of the product XX with ethyl diazoacetate and boron trifluoride etherate gave rise to keto ester XXI. When heated at reflux with sodium hydroxide in ethanol and water, keto ester XXI underwent concomitant decarbethoxylation and cyclization to give (-)-khusimone (I). On treatment with dimethyl sulfonium methyliue y.Lide, (-)- khusimone (I) was transformed to epoxide XXII. Boron trifluoride catalyzed rearrangement of epoxide XXII afforded aldehyde XXIII which was subsequently oxidized with Jones reagent- to give (-)- epizizanoic acid (II). Alternatively, epimerization of aldehyde XXIII to XXIV 7 followed by Jones oxidation resulted in the formation of (t)-zizanoic acid (III). In the second part of this thesis, the preparation of trione XXV, a potential synthetic precursor of cedrenoi.d sesquiterpenes, is described. (-)-a-Canpholenic acid (V) was first, converted to ketone XXVI by treatment with methyllithium. Photcoxidation of ketone XXVI followed by reductive work-up with trietayl phosphite gave rise to epimeric alcohols XXVII which were subsequently oxidized with active manganese dioxide to give enone XXVII, Addition of 1-nitropropane to enone XXVIII was effected by u r - mg potassium carbonate as a base. The salt derived from tJie oroduct XXIX and one equivalent of sodium methoxide in methanol was subjected to ozonolysis. Reductive work-up using dimethyl sulfide afforded trione XXV. Results obtained from the preliminary studies on the transformation of trione XXV to cedrenoid sesquiterpenes are also discussed.
Download or read book Fragrance Chemistry written by Ernst T. Theimer and published by Elsevier. This book was released on 2012-12-02 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been prepared as an introduction to the chemistry of odorous molecules. While there exist a number of works of an encyclopedic nature which cover this field, there is none which treats the subjectin an instructional fashion. To fill this gap, a group of scientists, types from the chemical point of view, to present to the reader the panorama of those molecules that stimulate the sense of smell. To make the picture complete, the chapters that are strictly chemical in content are preceded by several that introduce the topics of the physiology of the olfactory system, the current hypotheses on the mechanism of the sense of smell, and the structure-odor relationships in odorous molecules. There is also a treatment of analytical techniques which have become important to fragrance chemical research and testing.
Download or read book Natural Products Chemistry written by Koji Nakanishi and published by Academic Press. This book was released on 2013-10-22 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products Chemistry, Volume 1 covers the introductory survey, history, structure, synthesis, reactions, and biosynthesis of natural products. The book discusses the classification of natural products; physico-chemical data on natural products; and the mono- and sesquiterpenes. The text also describes the structure and biosynthesis of sester-, tri- and higher terpenoids, as well as of the steroids. Chemists, biochemists, and microbiologists will find the book invaluable.
Download or read book Essentials of Medicinal and Aromatic Crops written by Muhammad Zia-Ul-Haq and published by Springer Nature. This book was released on 2023-10-09 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal and aromatic crops (MACs) are high-value crops since the natural products obtained from them are low-volume high-value commodities that have numerous applications in various sectors such as the food, beverage, food supplement, flavor and fragrance, perfumery and cosmetics, pharmaceutical and aromatherapy industries. In addition, the plant biomass is used in the production of teas and medical applications in traditional and also modern medicines. MACs are important mainly because they contain plant secondary metabolites such as essential oils, alkaloids, glygosides, saponins, tannins, vitamins and other bioactives. Plant secondary metabolites are differentiated from plant primary metabolites of photosynthesis and respiration since they are directly involved in growth and development of plants. Some MACs are used as spices and culinary herbs since they contain mainly essential oils, and are used as tonic to the digestive system, appetite modification and other systems and may facilitate nutrient uptake and utilization from various foods. A significant amount of MACs and their natural products have also demonstrated antimicrobial, antifungal and bactericidal activity and significant antioxidant capacity. In the past, MACs and their natural products have been used as a source for various medicines, in food and beverage production and in aroma products. Essentials of Medicinal and Aromatic Crops summarizes the current knowledge on medicinal and aromatic crops, including the agronomical practices of important MACs and their products, their beneficial effects and utilization of MAP and their products. The chapters provide a comprehensive guide to the most important and used medicinal and aromatic crops and their use in functional foods, nutraceuticals and as bioactives against various ailments, providing researchers, teachers, chemists, food scientists, agronomists and agroecologists in academia, industry and government a fully up to date singular source on this important topic.
Download or read book The Total Synthesis of Natural Products Volume 2 written by John ApSimon and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume reviews the total synthesis of a set of compounds looking at syntheses reported historically and at the practice current at the time of publication. From volume 1 focusing on carbohydrates, prostagladins, nucleic acids, antibiotics, naturally occurring oxygen ring compounds and pyrrole pigments, the series continues with coverage of aromatic steroids, monoterpenes, triterpenes, sesquiterpenes, cannabinoids, natural inophores, insect pheromones and alkaloids. Volumes revisit the total synthesis of key compounds such as carbohydrates, nucleic acids and pyrrole pigments several times during the series building a picture of the historic development of total synthesis techniques for these major groups. Chapters are edited by experts in their field to give a complete overview of the best in the field at the time.
Download or read book Fortschritte der Chemie Organischer Naturstoffe Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Terpenoids and Steroids written by Karl Howard Overton and published by Royal Society of Chemistry. This book was released on 1972 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Vetiveria written by Massimo Maffei and published by CRC Press. This book was released on 2002-01-17 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vetiveria is one of the most versatile genera in plant kingdom. For example, the species Vetiveria zizanoides produces oderous roots from which a precious essential oil is distilled and used in a variety of applications from perfumery to ethnopharmacology. The same roots give the plant particular characteristics that make it a valuable natural barr
Download or read book The Total Synthesis of Natural Products Volume 5 written by John ApSimon and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume reviews the total synthesis of a set of compounds looking at syntheses reported historically and at the practice current at the time of publication. From volume 1 focusing on carbohydrates, prostagladins, nucleic acids, antibiotics, naturally occurring oxygen ring compounds and pyrrole pigments, the series continues with coverage of aromatic steroids, monoterpenes, triterpenes, sesquiterpenes, cannabinoids, natural inophores, insect pheromones and alkaloids. Volumes revisit the total synthesis of key compounds such as carbohydrates, nucleic acids and pyrrole pigments several times during the series building a picture of the historic development of total synthesis techniques for these major groups. Chapters are edited by experts in their field to give a complete overview of the best in the field at the time.
Download or read book The logic of chemical synthesis written by E.J. Corey and published by Рипол Классик. This book was released on 1991 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medicinal Plants written by Thomas S. C. Li and published by CRC Press. This book was released on 2000-06-16 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Plants: Culture, Utilization and Phytopharmacology covers over 400 species. Each chapter gathers valuable information from a wide variety of sources, and supplies it to the user in convenient table format, arranged alphabetically by scientific name, followed by the common name. Data topics include: major constituents (active ingredients)
Download or read book CRC Handbook of Alternative Cash Crops written by James A. Duke and published by CRC Press. This book was released on 1993-08-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CRC Handbook of Alternative Cash Crops describes 128 crop plants that can be grown as alternatives to cultivated crops, such as tobacco, and narcotic crops, such as opium poppy. Material is presented in alphabetical order by genus and species and includes information on ecology, cultivation, harvesting, economics, and biotic factors. This book will be valuable to AID agents, domestic agricultural extension agents, and soil and crop professionals worldwide.
Download or read book Studies in Natural Products Chemistry written by Atta-ur Rahman and published by Elsevier. This book was released on 1998-12-03 with total page 1365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products Chemistry continues to grow at an increasing pace and this growth is reflected in the present volume of Studies in Natural Products Chemistry, which is the 20th of this series. The first 20 volumes were largely devoted to structure and synthesis of various classes of natural products, irrespective of their bioactivity. Subsequent volumes of this series will however be devoted to the chemistry of bioactive natural products and will therefore a departure from the earlier volumes. The present volume contains contributions from a number of eminent scientists and covers interesting reviews on terpenes, alkaloids and other types of natural products reported from terrestrial and marine sources. Comprehensive indexes covering all the 20 volumes have been prepared which include a Cumulative General Subject Index along with more focused Cumulative Indices on Organic Synthesis, Pharmacological Activity and Biological Source. This comprehensive indexing of the volumes should make the entire series much more valuable and user-friendly.
Download or read book Bibliography of Agriculture written by and published by . This book was released on 1968 with total page 1492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
