Download or read book YEAR OF THE COMET written by SERGEI. LEBEDEV and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In the Days of the Comet written by Herbert George Wells and published by . This book was released on 1906 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 30 years of the Comet Assay an overview with some new insights written by Amaya Azqueta and published by Frontiers Media SA. This book was released on 2015-08-21 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: By means of this ‘Frontiers in Genetics’ research topic, we are celebrating 30 years of the Comet Assay. The first paper on this single-cell gel electrophoresis assay was published in 1984 by O. Ostling and K.J. Johanson (Biochem. Biophys. Res. Commun. Vol.123: 291-298). The comet assay is a versatile and sensitive method for measuring single - and double-strand breaks in DNA. By including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute. The comet assay (with and without inclusion of lesion-specific enzymes) is widely used as a biomarker assay in human population studies - primarily to measure DNA damage, but increasingly also to assess the capacity of cells for DNA repair. Ostling and Johanson (Biochem. Biophys. Res. Commun., 1984) were also the first to report experiments to measure DNA repair, by simply following the decrease of DNA damage over time after challenging cells with ionising radiation. However, this approach is time-consuming and laborious as it requires an extended period of cell culture and is therefore not ideal for biomonitoring studies, which typically require high-throughput processing of many samples. As an alternative approach, the in vitro comet-based repair assay was developed: a cell extract is incubated with a DNA substrate containing specific lesions, and DNA incisions accumulate. The in vitro comet-based repair assay has been modified and improved over the past decade: it was first devised to measure base excision repair of oxidised purines in lymphocytes (Collins et al., Mutagenesis, 2001), but has since been adapted for other lesions and thus other repair pathways, as well as being applied to tissue samples in addition to cell suspensions. Even after 30 years, the comet assay is still in a growth phase, with many new users each year. Many questions are repeatedly raised, which may seem to have self-evident answers, but clearly, it is necessary to reiterate them for the benefit of the new audience, and sometimes being forced to think again about old topics can shed new light. Different applications of the comet assay are discussed in this special issue, including: genotoxicity testing in different organisms, human biomonitoring, DNA repair studies, environmental biomonitoring and clinical studies. Furthermore, we consider and where possible answer questions, including the ones raised by Raymond Tice at the 8th International Comet Assay Workshop in Perugia (Italy 2009): What is the spectrum of DNA damage detected by the various versions of the comet assay?; What are the limitations associated with each application?; What should be done to standardize the assay for biomonitoring studies?; Can the comet assay be used to monitor changes in global methylation status?; What cell types are suitable for detecting genotoxic substances and their effects in vivo and in vitro?; Can the assay be fully automated?; and more. So this ‘Frontiers in Genetics’ research topic is written for the beginner as well as for the experienced users of the comet assay.
Download or read book The Comet s Curse written by Dom Testa and published by Macmillan. This book was released on 2009-01-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Desperate to save the human race after a comet's deadly particles devastate the adult population, scientists create a ship that will carry a crew of 251 teenagers to a home in a distant solar system.
Download or read book The Comet of 1577 written by C.D. Hellman and published by Рипол Классик. This book was released on with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Night of the Comet written by George Bishop and published by Ballantine Books. This book was released on 2013-07-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: NAMED ONE OF THE BEST BOOKS OF THE YEAR BY KIRKUS REVIEWS From the acclaimed author of Letter to My Daughter comes an engrossing coming-of-age tale that deftly conveys the hopes and heartaches of adolescence and the unfulfilled dreams that divide a family, played out against the backdrop of a small southern town in 1973. For his fourteenth birthday, Alan Broussard, Jr., receives a telescope from his father, a science teacher at the local high school who’s eagerly awaiting what he promises will be the astronomical event of the century: the coming of Comet Kohoutek. For Alan Broussard, Sr.—frustrated in his job, remote from his family—the comet is a connection to his past and a bridge to his son, with whom he’s eager to share his love for the stars. But the only heavenly body Junior has any interest in is his captivating new neighbor and classmate, Gabriella Martello, whose bedroom sits within eyeshot of his telescope’s lens. Meanwhile, his mother, Lydia, sees the comet—and her husband’s obsession with it—as one more thing that keeps her from the bigger, brighter life she once imagined for herself far from the swampy environs of Terrebonne, Louisiana. With Kohoutek drawing ever closer, the family begins to crumble under the weight of expectations, until a startling turn of events will leave both father and son much less certain about the laws that govern their universe. Illuminating and unforgettable, The Night of the Comet is a novel about the perils of growing up, the longing for connection, and the idea that love and redemption can be found among the stars. Praise for The Night of the Comet “A quiet, occasionally bittersweet novel about the differences between desire and disappointment, expectations and reality.”—Booklist “Coming-of-age novels examine youthful revelations about the world—filled with cynicism and wonder and rearranged expectations—and the quality hinges on the honesty of the voice, the truth of the observations, the handling of innocence lost; Bishop succeeds on all these fronts.”—Kirkus Reviews “Resonant . . . explores the complexities of a father-son relationship through science, astronomy, and the growing pains of adolescence. . . . Bishop’s characterizations of young Alan’s mother, father, and sister Megan are endearing and their relentless coddling of their maturing son is wincingly accurate.”—Publishers Weekly “Hilarious and heart-wrenching, ethereal and earthy, The Night of the Comet points us to the fragile universe of dreams and disappointments, joy and tragedy, saying here it is, all of it: feast your eyes on the magic. It’s a heavenly book. Nobody writes about the gravitational pull of parent-child relationships—all that we yearn for and all that we can’t have—like George Bishop.”—Minrose Gwin, author of The Queen of Palmyra “Equally sweet and sad, this is a fine novel of love and forgiveness.”—Stewart O’Nan, author of Snow Angels “Bishop’s one of our best, and this book’s a quiet marvel.”—Josh Russell, author of Yellow Jack “A deft, clear-eyed, and sensitive examination of the mysterious bonds of family, the allure of the unattainable, and love and desire—and their consequences—in all their many forms.”—Ellen Baker, author of I Gave My Heart to Know This
Download or read book Heart of the Comet written by Gregory Benford and published by . This book was released on 2012-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A group of men and women, from a shattered society, ride a ball of ice through the solar system in search of a future.
Download or read book A judgement of the comet visible in Dublin December 1680 By a Person of Quality Bishop E Wetenhall written by and published by . This book was released on 1682 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Comet written by W. E. B. Du Bois and published by Graphic Arts Books. This book was released on 2021-06-08 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comet (1920) is a science fiction story by W. E. B. Du Bois. Written while the author was using his role at The Crisis, the official magazine of the NAACP, to publish emerging black artists of the Harlem Renaissance, The Comet is a pioneering work of speculative fiction which imagines a catastrophic event not only decimating New York City, but bringing an abrupt end to white supremacy. “How silent the street was! Not a soul was stirring, and yet it was high-noon—Wall Street? Broadway? He glanced almost wildly up and down, then across the street, and as he looked, a sickening horror froze in his limbs.” Sent to the vault to retrieve some old records, bank messenger Jim Davis emerges to find a city descended into chaos. A comet has passed overhead, spewing toxic fumes into the atmosphere. All of lower Manhattan seems frozen in time. It takes him a few moments to see the bodies, piled into doorways and strewn about the eerily quiet streets. When he comes to his senses, he finds a wealthy woman asking for help. Soon, it becomes clear that they could very well be the last living people in the planet, that the fate of civilization depends on their ability to come together, not as black and white, but as two human beings. But how far will this acknowledgment take them? With a beautifully designed cover and professionally typeset manuscript, this edition of W. E. B. Du Bois’ The Comet is a classic work of African American literature reimagined for modern readers.
Download or read book The Comet of 1556 written by John Russell Hind and published by . This book was released on 1857 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Almanack for the Year of Our Lord written by Joseph Whitaker and published by . This book was released on 1926 with total page 1082 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Year of the Comet written by John Christopher and published by . This book was released on 1955 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Night of the Comet written by George Bishop (Jr.) and published by . This book was released on 2013 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fourteen-year-old Alan Broussard is swept up in his science teacher father's community-wide comet-watching activities, which illuminate for the young teen his father's inadequacies, his mother's unhappiness, and his own loss of innocence.
Download or read book Miscellaneous Reflections Occasion d by the Comet which Appear d in December 1680 written by Pierre Bayle and published by . This book was released on 1708 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Comet Scientific Notices of Comets in General and in Particular of the Comet of 1832 Translated by Colonel C Gold written by Dominique François J. Arago and published by . This book was released on 1833 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Three Hundred Years of Gravitation written by Stephen Hawking and published by Cambridge University Press. This book was released on 1987 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of reviews by prominent researchers in cosmology, relativity and particle physics commemorates the 300th anniversary of Newton's Philosophiae Naturalis Principia Mathematica.
