Download or read book Tissue Repair and Fibrosis written by Alexis Desmouliere and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Download or read book Tissue Repair Contraction and the Myofibroblast written by Christine Chaponnier and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Repair, Contraction and the Myofibroblast summarizes the latest findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. Coverage shows that the myofibroblast is responsible for the development of hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma. Reviews the cell biology and pathology of the myofibroblast as well as mechanisms of fibrosis evolution in many organs and tissues.

Download or read book Wound Healing Fibrosis and the Myofibroblast written by Giulio Gabbiani and published by Academic Press. This book was released on 2021-09-28 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history). By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research. Interdisciplinary collaboration: complementary views from medical historian, a physician and a researcher A concise but detailed history of fibrosis, readers can discover the major scientific breakthroughs along this history Includes the pathophysiology of various fibrotic diseases Explores the role of myofibroblast in fibrosis development

Download or read book Textbook on Scar Management written by Luc Téot and published by Springer Nature. This book was released on 2020-12-07 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Download or read book Stellate Cells in Health and Disease written by Chandrashekhar Gandhi and published by Academic Press. This book was released on 2015-04-10 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

Download or read book Pathogenesis of Fibrosis written by and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Myofibroblasts written by Analise Martinez and published by Nova Science Publishers. This book was released on 2016 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myofibroblasts play a major role in connective tissue remodeling by synthesizing the extracellular matrix (ECM) and by exerting contraction, both of which depend on complex and specific cell-matrix and cell-cell communications. Integrins are a major family of transmembrane receptors that directly link the intracellular cytoskeleton dynamics to extracellular structures via adhesions in all metazoans. In this book, Chapter One discusses major integrins that have an established role in the formation, function, and turnover of myofibroblasts associated with tissue remodeling. Chapter Two reviews the role of myofibroblasts in normal skin wound healing. Chapter Three summarizes the evidence for the presence and role of myofibroblasts in cancer progression and discusses the similarities of myofibroblasts in cancer and fibrosis. Chapter Four focuses on the role of bone marrow stem cells and bone marrow stem cell derived myofibroblasts in carcinogenesis and cancer development, and ways to inhibit the process of malignization.

Download or read book Wound Healing written by Vlad Alexandrescu and published by BoD – Books on Demand. This book was released on 2016-10-12 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Outstanding scientific advances over the last decades unceasingly reveal real complexity of wound-healing process, astonishing in its staged progression, as life is unfolding itself. This natural course of tissue repair seems to bear thousands of overlapping molecular and macroscopic processes that nowadays only start to unfold to our knowledge. The present volume collecting recent scientific references proposes to readers a two-folded audacious goal. First, an updated design of intimate cellular mechanisms is entailed in tissue regeneration that emanates from the first section of the book. Next, a multidisciplinary therapeutic perspective that focuses on macroscopic healing throughout the second part of this work adds clinically integrated observation. Practical diagnostic and treatment information is appended in each chapter that may equally help experienced clinicians or dedicated students and researchers in broadening essential breaking points of their work. It is the wish of all multidisciplinary experts who gather prominent author's panel of this volume to incorporate latest medical reports and compel limits of current understanding for better tissue regeneration, limb salvage, and improved quality of life of our patients.

Download or read book Practical Soft Tissue Pathology A Diagnostic Approach E Book written by Jason L. Hornick and published by Elsevier Health Sciences. This book was released on 2017-11-14 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the in-depth and practical Pattern Recognition series, Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you arrive at an accurate diagnosis by using a proven pattern-based approach. Leading diagnosticians guide you through the most common patterns seen in soft tissue pathology, applying appropriate immunohistochemistry and molecular testing, avoiding pitfalls, and making the best diagnosis. High-quality illustrations capture key morphologic patterns for a full range of common and rare tumor types, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. A consistent chapter organization by histologic pattern considers soft tissue tumors the way you approach them in daily practice, helping you arrive at a quick and accurate diagnosis. A user-friendly design color-codes patterns to specific entities, and key points are summarized in tables and text boxes, so you can quickly and easily find what you are looking for. Sweeping content updates keep you at the forefront of recent findings regarding all major neoplastic and non-neoplastic diseases of the soft tissues. Improved pattern call-outs are now linked directly within the chapter, reinforcing the patterns for more efficient and complete understanding.

Download or read book Renal Fibrosis Mechanisms and Therapies written by Bi-Cheng Liu and published by Springer. This book was released on 2019-08-09 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.

Download or read book Histology for Pathologists written by Stacey E. Mills and published by Lippincott Williams & Wilkins. This book was released on 2012-07-16 with total page 3002 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong grounding in basic histology is essential for all pathologists. However, there had always been a gap between histology and pathology in which histologic information specifically for the pathologist was often lacking. Histology for Pathologists deals with the microscopic features of normal human tissues, from the perspective of the surgical pathologist. This is the only text that uses human (vs. animal) tissues for the histology. It is the best reference in the literature for information on normal histology, and, as such, is essential for all clinical pathologists. Written by pathologists for pathologists, the new edition updates the pathologist's understanding of normal histology up to date with the incremental advances made in the last five years. The 3rd edition has become a "classic" purchased by virtually all residents beginning their pathology training, as well as pathologists in practice. The 4th edition builds on that substantial foundation. The table of contents remains essentially the same with the exception of some changes in authorship.

Download or read book The Molecular and Cellular Biology of Wound Repair written by R.A.F. Clark and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and the cellular movements and processes....This is an excellent reference book for libraries serving biology and health science clientele and for workers in this field of research.' -American Scientist, from a review of the First Edition All chapters of this second edition have been completely revised and expanded-especially the chapters on growth factors and extracellular matrix molecules. New chapters discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing.

Download or read book Diagnostic Cytopathology written by Winifred Gray and published by . This book was released on 2003 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Cytopathology provides the clinician with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and will cover the recognised normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is heavily illustrated to ensure that it will be a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will expedite the clinician's search for answers to any query. in-depth bench book that covers everyday diagnostic work. Provides the clinician with an accessible guide to diagnostic investigation and screening. Cytologic findings closely related to histology. Provides the general diagnostic pathologist in the interpretation and recognition of tissue samples. Each chapter provides a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Enables the clinician to use cytology services more effectively. Major revisions of the following chapters: Mesotheliomas, Malignant Breast Tumours, Lymph Nodes, The Pathogenesis of Cervical Neoplasia, Cervical intraepithelial neoplasia and Squamous Carcinoma of the Cervix. Brand new chapter on Automation which is increasingly important in cervical screening. Additional material on Thin Core Biopsy technique which is increasingly used in Breast Screening Program. Inclusion of new genetic markers in immunohistochemistry increasingly important in non-gynaecological areas. With 47 additional contributors.

Download or read book Blumgart s Surgery of the Liver Pancreas and Biliary Tract E Book written by William R. Jarnagin and published by Elsevier Health Sciences. This book was released on 2016-10-10 with total page 2520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised with new illustrations, new clinical photos, this classic text remains the most comprehensive and up-to-date resource on surgery of the hepatobiliary and pancreatic region. Dr. William Jarnagin and his team of internationally recognized surgeons continue the Blumgart’s tradition of excellence, bringing you the latest advances in diagnostic and surgical techniques. You’ll find updates on the newest minimally invasive surgeries, new interventional diagnostic techniques, and complete coverage of all relevant diseases, including those seen in the tropics. Considers all worldwide opinions and approaches to management, and includes key data on surgical outcomes to better inform your clinical decision-making. Covers exactly what you need to know, balancing basic science with information on clinical practice. Presents cutting edge guidance on pathology, diagnostics, surgery and non-operative intervention of the liver, biliary tract, and pancreas in a single, comprehensive reference. Covers the most recent non-surgical therapies for pancreatic cancer, microwave ablation, and other emerging technologies. Brings you up to date with recent developments in transplantation, minimally invasive surgery, percutaneous devices, pre- and post-care, blood transfusion, and surgical techniques for the spleen. Features an extensively revised art and illustration program, with new anatomical line drawings (including hundreds now in color), more than 750 new clinical photos, more schematic diagrams that summarize information, and new graphs and algorithms throughout.

Download or read book Acute Chronic Wounds written by Ruth A. Bryant and published by Elsevier Health Sciences. This book was released on 2012-01-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Acute and chronic wounds / [edited by] Ruth A. Bryant, Denise P. Nix. 3rd ed. c2007.

Download or read book Equine Wound Management written by Ted S. Stashak and published by John Wiley & Sons. This book was released on 2011-11-16 with total page 1165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Equine Wound Management, Second Edition is a comprehensive, authoritative resource for both theoretical and practical information on the care of wounds in horses. Now highly illustrated with full-color photographs throughout, this long-awaited second edition is significantly expanded to include new developments and techniques in wound healing. Equine Wound Management is an essential reference for veterinary students, veterinary surgeons, veterinary dermatologists, and equine and large animal veterinarians.