Download or read book Validation Studies in the Regeneration of Ion Exchange Celluloses written by RMH Jones and published by . This book was released on 1996 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clean-in-place procedure involving storage in 0.5M-NaOH for several hours has been found effective in the regeneration of process-scale columns (25 1) of Express-Ion ion-exchange celluloses following preparative loadings (2-9 kg) of a hen egg-white protein feedstock. These conditions have been demonstrated to provide simultaneous sanitization of the media following a gross microbial challenge, as indicated by decreased bioburden and endotoxin levels. We have developed an ion chromatography procedure for detecting and quantitating potential hydrolysis products originating from the functional groups bonded to anion and cation-exchange media. Using these techniques we demonstrate no detectable leakage of functional groups from the ion-exchange celluloses during the bed regeneration process. There was no significant loss of glucose from the matrix during this procedure.
Download or read book Validation Practices for Biotechnology Products written by J. K. Shillenn and published by ASTM International. This book was released on 1996 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the current methods and practices by which companies that produce genetically altered drugs assure that all components and finished products have the identity, strength, quality, and purity that is purported and represented. Also considers possible improvements and whether industry standard
Download or read book Bioseparations of Proteins written by Ajit Sadana and published by Elsevier. This book was released on 1997-11-27 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption,process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures
Download or read book Journal of Chromatography written by and published by . This book was released on 1997 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guide to Protein Purification written by Richard R Burgess and published by Academic Press. This book was released on 2009-11-03 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guide to Protein Purification, Second Edition provides a complete update to existing methods in the field, reflecting the enormous advances made in the last two decades. In particular, proteomics, mass spectrometry, and DNA technology have revolutionized the field since the first edition’s publication but through all of the advancements, the purification of proteins is still an indispensable first step in understanding their function. This volume examines the most reliable, robust methods for researchers in biochemistry, molecular and cell biology, genetics, pharmacology and biotechnology and sets a standard for best practices in the field. It relates how these traditional and new cutting-edge methods connect to the explosive advancements in the field. This "Guide to" gives imminently practical advice to avoid costly mistakes in choosing a method and brings in perspective from the premier researchers while presents a comprehensive overview of the field today. Gathers top global authors from industry, medicine, and research fields across a wide variety of disciplines, including biochemistry, genetics, oncology, pharmacology, dermatology and immunology Assembles chapters on both common and less common relevant techniques Provides robust methods as well as an analysis of the advancements in the field that, for an individual investigator, can be a demanding and time-consuming process
Download or read book Advanced Ion exchange Celluloses written by and published by . This book was released on 196? with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advanced ion exchange celluloses written by Whatman Laboratories and published by . This book was released on 196? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ion Exchange written by Ayben Kilislioglu and published by BoD – Books on Demand. This book was released on 2015-09-09 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides broad coverage of ion exchange and its applications. Different chapters focus on the importance of ion exchange applications such as strengtening dental porcelains, gradient changes in glass refraction, and resins as effective sorbents. Each chapter includes a brief historical overview of ion exchange and its applications. The authors also give a brief overview of these applications as well as review current experimental data on the subject.
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1975 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applications of Ion Exchange Materials in Biomedical Industries written by Inamuddin and published by Springer. This book was released on 2019-01-30 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the applications of ion-exchange materials in the biomedical industries. It includes topics related to the application of ion exchange chromatography in determination, extraction and separation of various compounds such as amino acids, morphine, antibiotics, nucleotides, penicillin and many more. This title is a highly valuable source of knowledge on ion-exchange materials and their applications suitable for postgraduate students and researchers but also to industrial R&D specialists in chemistry, chemical, and biochemical technology. Additionally, this book will provide an in-depth knowledge of ion-exchange column and operations suitable for engineers and industrialists.
Download or read book Ion Exchange Chromatography written by Pharmacia LKB Biotechnology and published by . This book was released on 1991 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitrate Removal from Water Supplies by Ion Exchange written by Dennis A. Clifford and published by . This book was released on 1978 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mass Transfer and Kinetics of Ion Exchange written by L. Liberti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: While ion-exchange processes were originally used for the treatment of very dilute solutions, many applications for the treatment of concentrated solu tions have been developed in recent years. In these situations, the mass transfer bottlenecks are located in the~, rather than the liquid phase. Therefore, the development of quantitative models for ion-exchange kinetics requires knowledge about the conductance characteristics of ions and solvent in the solid phase. A useful approach towards this aim is the study of trans port characteristics of these species, and of their interactions in solid ion exchange membranes. Many different transport processes and related phenomena can be observed in membrane-solution systems, e.g., ion migration, electroosmosis, diffusion arid self-diffusion, osmosis, hydraulic flow, hyperfiltration (reverse osmosis) or ultrafiltration, streaming potential and streaming current, and membrane potentials (also called "membrane concentration potentials"). It is important to correlate all these phenomena so as to avoid a very large number of unnec essary measurements. Such correlation is often possible [Meares, 1976] since all these phenomena are determined by the ease of migration of the different species across the membrane. Important correlations have been made and summar ized even before high-capacity ion-exchange membranes became commercially available [Sollner, 1950, 197iJ.
Download or read book The Engineering Index Annual written by and published by . This book was released on 1988 with total page 2282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its creation in 1884, Engineering Index has covered virtually every major engineering innovation from around the world. It serves as the historical record of virtually every major engineering innovation of the 20th century. Recent content is a vital resource for current awareness, new production information, technological forecasting and competitive intelligence. The world?s most comprehensive interdisciplinary engineering database, Engineering Index contains over 10.7 million records. Each year, over 500,000 new abstracts are added from over 5,000 scholarly journals, trade magazines, and conference proceedings. Coverage spans over 175 engineering disciplines from over 80 countries. Updated weekly.
Download or read book New Trends in Ion Exchange Studies written by Selcan Karakus and published by BoD – Books on Demand. This book was released on 2018-11-07 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers new systems in technology that have developed our knowledge of ion exchange. This book discusses ion exchange resins to enhance cell growth; anion exchange membrane; nanosystems in ion exchange and ion exchange in environmental applications. The ion exchange system is used in bionanotechnology, cosmetic industry and water treatment.
Download or read book Abstract Bulletin written by Institute of Paper Chemistry (Appleton, Wis.) and published by . This book was released on 1970 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ion Exchange Technology I written by Inamuddin Dr. and published by Springer Science & Business Media. This book was released on 2012-06-02 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion-exchange Technology I: Theory and Materials describes the theoretical principles of ion-exchange processes. More specifically, this volume focuses on the synthesis, characterization, and modelling of ion-exchange materials and their associated kinetics and equilibria. This title is a highly valuable source not only to postgraduate students and researchers but also to industrial R&D specialists in chemistry, chemical, and biochemical technology as well as to engineers and industrialists.
