Download or read book Use of Toxicological and Chemical Models to Prioritize DBP Research written by Richard J. Bull and published by American Water Works Association. This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Little is known about the specific disinfection by-products (DBPs) in drinking water that may cause cancer in humans. In fact, toxicological research in the past decade has cast significant doubt on the risk associated with the THMs and HAAs that are subject to regulation. This research identifies from among hundreds of disinfection by-products formed by the chlorination of drinking water those DBPs that are most likely to cause human cancer. Identification of potential cancer-causing DBPs will help researchers prioritize further research.

Download or read book Disinfection By Products and Human Health written by Steve E. Hrudey and published by IWA Publishing. This book was released on 2012-04-30 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disinfection By-Products and Human Health is based on contributions from speakers who participated in May 2011 workshops on Disinfection By-Products (DBPs) and Human Health at Ozwater 11 in Adelaide, Australia or at an AWA sponsored workshop at the Curtin Water Quality Research Centre, Perth, Australia. The contributions are prepared to facilitate communication with practitioners, rather than researchers, making use of overview illustrations rather than dense text or data tables. Each chapter concludes with up to 5 key findings that are take-home messages for practitioners. Disinfection By-Products and Human Health is aimed specifically at drinking water professionals (engineers, chemists and public health professionals) working on the front lines of drinking water issues where they must encounter actual day-to-day issues of risk management concerning DBPs in relation to all the other regulatory and water quality issues they must manage. Although a topic this complex is certainly not amenable to simplistic explanations, this book aims to provide drinking water professionals with a pragmatic assessment of the current evidence and emerging issues concerning DBPs and public health. Disinfection By-Products and Human Health is an essential, practical and accessible guide for drinking water professionals, engineers, chemists and public health professionals. Editors: Steve E. Hrudey, Professor Emeritus, Analytical & Environmental Toxicology, University of Alberta, Canada, Jeffrey W.A. Charrois, Director and Associate Professor, Curtin Water Quality Research Centre, Curtin University of Technology, Australia, Steve Hrudey is professor emeritus in analytical and environmental toxicology in the University of Alberta's Faculty of Medicine & Dentistry. He spent 13 years as a cabinet-appointed member of the Alberta Environmental Appeals Board, the last four as chair, and was the first non-lawyer to hold this position. During this period, he served on 36 public hearing panels, 19 as chair of the panel. In addition he has testified before senate committees in Canada and the Legislative Council in Western Australia. Hrudey has served on a number of high-profile expert panels, including the Research Advisory Panel to the Walkerton Inquiry (2000-2002), the Expert Panel on Safe Drinking Water for First Nations (2006), the Technical Advisory Committee to the B.C. Minister of Health on turbidity and microbial risk in drinking water (2007-2008, as chair), the Expert Advisory Panel on Water Quality for Washington, D.C., to the U.S. Army Corps of Engineers (2009-2011) and chair of the Royal Society of Canada Expert Panel on Environmental and Health Impacts of Canada's Oil Sands Industry (2009-2010). He has also co-authored or edited nine books, including the widely acclaimed book inspired by the Walkerton tragedy: Safe Drinking Water - Lessons from Recent Outbreaks in Affluent Nations (IWA Publishing, 2004). He has written 26 book chapters, 19 expert panel reports, 163 refereed journal articles, 15 science discussions, six media op-eds and 73 conference proceeding papers. Hrudey is the 2012 winner of the American Water Works Association A.P. Black Research Award for contributions to water science and water supply. This book is sponsored by Australian Water Association (AWA)

Download or read book Water Quality Engineering written by Mark M. Benjamin and published by John Wiley & Sons. This book was released on 2013-07-01 with total page 906 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the fundamental theory and mathematics of water and wastewater treatment processes By carefully explaining both the underlying theory and the underlying mathematics, this text enables readers to fully grasp the fundamentals of physical and chemical treatment processes for water and wastewater. Throughout the book, the authors use detailed examples to illustrate real-world challenges and their solutions, including step-by-step mathematical calculations. Each chapter ends with a set of problems that enable readers to put their knowledge into practice by developing and analyzing complex processes for the removal of soluble and particulate materials in order to ensure the safety of our water supplies. Designed to give readers a deep understanding of how water treatment processes actually work, Water Quality Engineering explores: Application of mass balances in continuous flow systems, enabling readers to understand and predict changes in water quality Processes for removing soluble contaminants from water, including treatment of municipal and industrial wastes Processes for removing particulate materials from water Membrane processes to remove both soluble and particulate materials Following the discussion of mass balances in continuous flow systems in the first part of the book, the authors explain and analyze water treatment processes in subsequent chapters by setting forth the relevant mass balance for the process, reactor geometry, and flow pattern under consideration. With its many examples and problem sets, Water Quality Engineering is recommended as a textbook for graduate courses in physical and chemical treatment processes for water and wastewater. By drawing together the most recent research findings and industry practices, this text is also recommended for professional environmental engineers in search of a contemporary perspective on water and wastewater treatment processes.

Download or read book Uncharted Waters written by Anna Andersson and published by Linköping University Electronic Press. This book was released on 2021-02-15 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disinfection by-products (DBPs) are potentially toxic compounds formed when drinking water is treated with disinfectants, such as chlorine or chloramine. A large proportion of the exposure to DBPs is still unknown and the health risks observed through epidemiological studies cannot be explained by DBPs known today. In this thesis, a part of the unknown DBP fraction is investigated, covering a wide range of non-volatile, chlorine/bromine-containing DBPs. The goals were to investigate how the compositions of these DBPs differ between water treatment plants, how their occurrence changes in the distribution system until reaching consumers and how new treatment techniques can reduce their formation and toxicity. To analyze unknown DBPs, a non-targeted approach adopting ultra-high-resolution mass spectrometry, Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), was used, where the mass of molecules is measured with such accuracy that the elemental composition of individual DBPs can be calculated. A panel of bioassays was used to assess the combined toxic effects from these DBP mixtures. The results show that the formation of these DBPs to a large extent was specific to each water treatment plant and that local conditions influenced DBP formation, based on e.g., the abundance of organic material with certain chemical structures, bromide and disinfection procedure and agent (chlorine or chloramine). The DBPs were detected in both chlorinated and chloraminated water and in all tap water samples, demonstrating that they are part of human exposure. The number of DBP formulae decreased and the DBP composition changed between drinking water treatment and consumer taps, suggesting that DBP exposure to consumers is not necessarily resembling measurements at the treatment plants. Evaluation of new treatment techniques showed that suspended ion exchange and ozonation have potential to decrease the formation and toxic effects of DBPs and that the removal of organic matter can influence qualitative aspects of DBP formation, such as the proportions of chlorine-containing (less toxic) versus bromine-containing (more toxic) DBPs. Through increased knowledge about the role and relevance of non-volatile DBPs, this work can contribute to future monitoring and actions to reduce the health risks associated with DBPs in chlorinated or chloraminated drinking water. Desinfektionsbiprodukter (DBP:s) är potentiellt giftiga ämnen som bildas när dricksvatten renas med desinfektionsmedel såsom hypoklorit eller monokloramin. En stor del av exponeringen är ännu okänd och hittills kända DBP:s kan inte förklara de hälsorisker som förknippats med klorerat dricksvatten i epidemiologiska studier. I avhandlingen undersöks en relativt okänd fraktion av DBP:s som utgörs av icke-flyktiga, klor/brom-innehållande ämnen. Målen var att undersöka hur dessa DBP:s varierar mellan olika vattenverk, om de förekommer hos konsumenter och hur nya vattenreningstekniker kan minska dess bildandning och relaterad toxicitet. För att mäta okända DBP:s användes ultrahögupplöst masspektrometri (Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS)), med vilken massan hos molekyler kan bestämmas så exakt att atomsammansättningen för enskilda DBP:s kan räknas ut. En serie effektbaserade metoder som bygger på biologiska testsystem användes för att mäta kombinerade toxiska effekter från de studerade biprodukterna. Resultaten visar att största delen av bildade DBP:s var unik för varje vattenverk och att lokala förutsättningar påverkar vilka DBP:s som bildas, till exempel om det finns organiskt material med särskilda kemiska strukturer, bromid eller vilket desinfektionsmedel (klor eller kloramin) som används. De studerade biprodukterna detekterades både i klorerat och kloraminerat dricksvatten och i samtliga kranvatten, vilket innebär att de bidrar till konsumenters exponering. Antalet detekterade DBP:s minskade och sammansättningen ändrades mellan vattenverk och konsument, vilket innebär att DBP exponeringen hos konsumenter inte är densamma som mäts på vattenverken. En utvärdering av nya reningstekniker visade att suspenderat jonbyte och ozonering har potential att minska bildning och relaterad toxisk effekt från DBP:s och att borttagning av organiskt material kan påverka kvalitativa aspekter av DBP bildning, såsom proportionerna av klorerade (mindre toxiska) och bromerade (mer toxiska) DBP:s. Genom ökad insikt om icke-flyktiga DBP:s roll och relevans kan detta arbete bidra till att förbättra framtida uppföljning och insatser för att minska hälsorisker kopplade till DBP:s i klorerat eller kloraminerat dricksvatten.

Download or read book Environmental Toxicants written by Morton Lippmann and published by John Wiley & Sons. This book was released on 2009-03-26 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles

Download or read book Disinfection By products in Drinking Water written by Tanju Karanfil and published by Academic. This book was released on 2008 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of chapters on the latest international research findings, including emerging issues and state-of-the-art studies, related to disinfection by-product formation and control in drinking waters and treated wastewaters.

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Download or read book Encyclopedia of Environmental Health written by and published by Elsevier. This book was released on 2019-08-22 with total page 4896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Environmental Health, Second Edition, Six Volume Set presents the newest release in this fundamental reference that updates and broadens the umbrella of environmental health, especially social and environmental health for its readers. There is ongoing revolution in governance, policies and intervention strategies aimed at evolving changes in health disparities, disease burden, trans-boundary transport and health hazards. This new edition reflects these realities, mapping new directions in the field that include how to minimize threats and develop new scientific paradigms that address emerging local, national and global environmental concerns. Represents a one-stop resource for scientifically reliable information on environmental health Fills a critical gap, with information on one of the most rapidly growing scientific fields of our time Provides comparative approaches to environmental health practice and research in different countries and regions of the world Covers issues behind specific questions and describes the best available scientific methods for environmental risk assessment

Download or read book General and Applied Toxicology written by Bryan Ballantyne and published by . This book was released on 2009 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Some Chemicals Present in Industrial and Consumer Products Food and Drinking water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Download or read book Application of Systematic Review Methods in an Overall Strategy for Evaluating Low Dose Toxicity from Endocrine Active Chemicals written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-14 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.

Download or read book Toxicological Profile for N nitrosodimethylamine written by and published by . This book was released on 1989 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Emerging Freshwater Pollutants written by Tatenda Dalu and published by Elsevier. This book was released on 2022-01-29 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Freshwater Pollutants: Analysis, Fate and Regulations comprises of 20 chapters, all written by leading experts. This book is written in the most practical terms and is easy to understand, with numerous helpful examples and case studies and can be used as a practical guide and important educational tool on issues concerning freshwater emerging pollutants. The organisation of the book exposes the reader in logical succession to the full range of complex scientific and management aspects of emerging freshwater pollutants in the developing world. The book recognises that water chemistry, emerging freshwater pollutants and management are inter-dependent disciplines. The book covers (i) the different monitoring techniques, current analytical approaches and instrumental analyses, (ii) fate and occurrence of emerging pollutants in aquatic systems and (iii) management policies and legislations on emerging pollutants. Thus, subsequent chapters elucidate chemicals with pollution potential, multi-detection approaches to analysis of organic pollutants in water, microplastics effects and photochemical transformation of emerging pollutants in freshwater systems. Whereas, other chapters address oxidation of organic compounds in aquatic systems, biomonitoring systems for detection of toxic levels of water pollutants, and health aspects of water recycling practices. This book melds several different perspectives on the subject of freshwater emerging pollutants and shows the interrelationships between the various professions that deal with water quality issues. Further, within the presentation of each separate chapter is discussion of how the various scientific and management aspects of the subject interrelate. - Includes case studies and practical examples in each chapter - Presents a much-needed interdisciplinary approach, representing the overlap between water chemistry and emerging freshwater pollutants - Provides a thorough introduction to emerging tropical and freshwater pollutants that typically occur in these systems

Download or read book IPCS Risk Assessment Terminology written by International Program on Chemical Safety and published by World Health Organization. This book was released on 2004 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: A joint project of IPCS/OECD. In two parts: Part 1: IPCS/OECD Key Generic Terms used in Chemical Hazard/Risk Assessment. Part 2: IPCS Glossary of Key Exposure Assessment Terminology. IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals

Download or read book Phthalates and Cumulative Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2009-01-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Download or read book Mammalian Cell Cytotoxicity and Genotoxicity of Disinfection By products written by and published by American Water Works Association. This book was released on 2009 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This project represents basic research to generate quantitative, comparative in vitro mammalian cell toxicity data of emerging DBPs and related compounds. It is the first systematic cytotoxicity and genotoxicity analysis of its kind --

Download or read book Bioanalytical Tools in Water Quality Assessment written by Beate Escher and published by IWA Publishing. This book was released on 2011-12-15 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of Water Quality Set - Buy all four books and save over 30% on buying separately! Bioanalytical Tools in Water Quality Assessment reviews the application of bioanalytical tools to the assessment of water quality including surveillance monitoring. The types of water included range from wastewater to drinking water, including recycled water, as well as treatment processes and advanced water treatment. Bioanalytical Tools in Water Quality Assessment not only demonstrates applications but also fills in the background knowledge in toxicology/ecotoxicology needed to appreciate these applications. Each chapter summarises fundamental material in a targeted way so that information can be applied to better understand the use of bioanalytical tools in water quality assessment. Bioanalytical tools in Water Quality Assessment can be used by lecturers teaching academic and professional courses and also by risk assessors, regulators, experts, consultants, researchers and managers working in the water sector. It can also be a reference manual for environmental engineers, analytical chemists, and toxicologists. Authors: Beate Escher, National Research Centre for Environmental Toxicology (EnTox), The University of Queensland, Australia, Frederic Leusch, Smart Water Research Facility (G51), Griffith University Gold Coast Campus, Australia. With contributions by Heather Chapman and Anita Poulsen