Download or read book Updates on Intrinsically Photosensitive Retinal Ganglion Cells written by Zhang Yan and published by Scientific Research Publishing, Inc. USA. This book was released on 2021-09-03 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Melanopsin Vision written by Daniel S. Joyce and published by Cambridge University Press. This book was released on 2023-01-31 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrinsically photosensitive retinal ganglion cells (ipRGGs) are the most recently discovered photoreceptor class in the human retina. This Element integrates new knowledge and perspectives from visual neuroscience, psychology, sleep science and architecture to discuss how melanopsin-mediated ipRGC functions can be measured and their circuits manipulated. It reveals contemporary and emerging lighting technologies as powerful tools to set mind, brain and behaviour.
Download or read book Seeing Without Rods Or Cones Contributions of Intrinsically photosensitive Retinal Ganglion Cells to the Image forming Visual System written by Stewart Madon and published by . This book was released on 2013 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: "It was long thought that rods and cones were the only components of the mammalian retina capable of conveying light information to the brain. Recently, a novel class of transduction-capable retinal ganglion cells containing the photopigment melanopsin were discovered in the mammalian retina identified as an “intrinsically photosensitive retinal ganglion cell” or ipRGC. Most of the functionality associated with ipRGCs has been linked to nonperceptual, non-cortical visual operations such as circadian (day-night) phase modulation and pupillary constriction. More recently, however, two subpopulations of ipRGCs have been identified called M1 and M2 cells, with the latter showing “blue-yellow” chromatic opponency that possibly links to brightness or colour pattern vision – properties associated with the retinogeniculostriate, or image-forming visual system. The present study expands on the current understanding of these putative image-forming non-traditional photoreceptor systems. To this end, I developed two stimulus paradigms that target short-wavelength-sensitive cones (S-cones) to tease out the unique contributions of ipRGCs that have neural associations with S-cone visual functioning. In the first paradigm, I measured detection thresholds using short-wavelength selective stimuli that are temporally presented with either an onset or offset “sawtooth” profile to ascertain ipRGC input to the S-OFF, “brightness” pathways. The results revealed differences in the asymmetry between S-ON and S-OFF pathways dependent upon adapting field conditions that were expected to influence ipRGCs over other photoreceptors. In the second experiment, I used a modification of an S-cone contrast sensitivity task employing homochromatic “blue” sine-grating gabors of varying spatial frequencies to directly test ipRGC involvement in spatial pattern vision. The results from the second experiment showed a slight advantage to the perception of low spatial frequency gabors superimposed on chromatic adapting fields that were expected to influence ipRGCs more than the others. Preliminary evidence supporting a spatial tuning property of ipRGCs was also found. Overall, these findings suggest that ipRGCs have measurable influences on conscious, image-forming perceptions, and shed further light on the microcircuitry of the retinogeniculate pathway."-- from abstract.
Download or read book Determination Whether Intrinsically Photosensitive Retinal Ganglion Cells Influence Contrast Sensitivity written by 包家榮 and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Determine the Neuronal Circuits of M1 Intrinsically Photosensitive Retinal Ganglion Cells ipRGCs at the Single cell Level and Their Downstream Functions written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Light History Modulates Social Memory in Mice Through Intrinsically Photosensitive Retinal Ganglion Cells written by 廖柏喻 and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Loss of Intrinsically Photosensitive Retinal Ganglion Cells Affects the Process of Retinal Vascular Development and the Distance Between Different Vascular Layers written by 許喬原 and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Retina written by John E. Dowling and published by Harvard University Press. This book was released on 2012-01-15 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Dowling’s The Retina, published in 1987, quickly became the most widely recognized introduction to the structure and function of retinal cells. In this Revised Edition, Dowling draws on twenty-five years of new research to produce an interdisciplinary synthesis focused on how retinal function contributes to our understanding of brain mechanisms. The retina is a part of the brain pushed out into the eye during development. It retains many characteristics of other brain regions and hence has yielded significant insights on brain mechanisms. Visual processing begins there as a result of neuronal interactions in two synaptic layers that initiate an analysis of space, color, and movement. In humans, visual signals from 126 million photoreceptors funnel down to one million ganglion cells that convey at least a dozen representations of a visual scene to higher brain regions. The Revised Edition calls attention to general principles applicable to all vertebrate retinas, while showing how the visual needs of different animals are reflected in their retinal variations. It includes completely new chapters on color vision and retinal degenerations and genetics, as well as sections on retinal development and visual pigment biochemistry, and presents the latest knowledge and theories on how the retina is organized anatomically, physiologically, and pharmacologically. The clarity of writing and illustration that made The Retina a book of choice for a quarter century among graduate students, postdoctoral fellows, vision researchers, and teachers of upper-level courses on vision is retained in Dowling’s new easy-to-read Revised Edition.
Download or read book Intrinsically Photosensitive Melanopsin Retinal Ganglion Cell Contributions to the Post illumination Pupil Response and Circadian Rhythm written by Emma Louise Markwell and published by . This book was released on 2011 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Intrinsically Photosensitive Retinal Ganglion Cell ipRGC Pathway and Its Role in Light Induced Discomfort in Humans written by Marija Zivcevska and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photophobia is a complex phenomenon defined by light-driven painful sensations; commonly associated with pathology. Although underlying mechanisms remain poorly understood and no objective assessment exists, growing evidence suggests that the melanopsin-containing intrinsically photosensitive retinal ganglion cell (ipRGC) light irradiance pathway plays a critical role in transducing light into a painful percept. The purpose of this thesis is to investigate the properties of the recently discovered ipRGC pathway and its role in mediating light-induced discomfort. Using chromatic pupillometry, Study 1 demonstrates that melanopsin-mediated ipRGC signals are summated binocularly, a fundamental extension of the current understanding of this pathway. Using a novel objective tool to quantify light-induced visual discomfort, Study 2 then provides in-vivo evidence linking perceptual experience with features of the melanopsin system, which may mediate photophobia. In sum, this thesis expands our current understanding of the melanopsin pathway, and provides novel tools to assess photophobia in different clinical populations.
Download or read book G Protein Signaling Mechanisms in the Retina written by Kirill A. Martemyanov and published by Springer. This book was released on 2014-09-04 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light. The organization of this volume will generally follow the path of signal flow in the retina. First we will describe recent advances in understanding the phototransduction cascade of rod and cone photoreceptors, which use signaling cascade based on the GPCR rhodopsin to transduce incident light into neural activity. Chapters will be devoted to unique specializations of the two major types of photosensitive cells that comprise the predominant input for our spatial and color vision. Subsequently, the mechanisms of synaptic information encoding by retinal ON bipolar cells will be described, where the GPCR mGluR6 plays a fundamental role. Chapters in this section will examine macromolecular organization of the mGluR6 signaling pathway as well as current understanding of its function. The functional characteristics of this signaling mechanism will be explored in detail. Additionally, this section will cover the role of dopamine receptors in modulating signal transmission between photoreceptors and ON-bipolar cells. Finally, chapters will be focused on the output neurons of the inner retina, ganglion cells, where the components of the emerging GPCR melanopsin cascade in intrinsically photosensitive ganglion cells will be detailed. Collectively these mechanisms allow the retina to represent visual space over a wide range of light intensities.
Download or read book Encyclopedia of Sleep written by and published by Academic Press. This book was released on 2013-01-17 with total page 2626 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference. 2013 PROSE Award winner for Multivolume Reference in Science from the Association of American Publishers Thoroughly interdisciplinary: looks at sleep throughout the life cycle, with exceptional coverage of basic sleep concepts, the physiology of sleep as well as sleep disorders of all descriptions Excellent coverage of sleep and special populations, covering the lifespan, as well as gender and ethnic differences, among others Chapters focusing on sleep disorders are grouped under the broad categories classified in the ICSD-2 for clear organization so that the reader can effectively access the steps involved in diagnosing and treating these disorders Online version is linked both within the encyclopedia (to related content) and to external sources (such as primary journal content) so that users have easy access to more detailed information if needed
Download or read book The Neurobiology of Circadian Timing written by A. Kalsbeek and published by Elsevier. This book was released on 2012-09-21 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Download or read book Diversity in the Neuronal Machine written by Ivan Soltesz and published by Oxford University Press. This book was released on 2006 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aims to provide insights into the striking degree of cellular diversity found in the interneuronal microcircuits in the brain's neocortex and hippocampus. This book elaborates on different ideas about interneuronal diversity that rest upon theoretical and experimental results and is useful for neuroscientists.
Download or read book Retinal Development written by Evelyne Sernagor and published by Cambridge University Press. This book was released on 2012-11-29 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced text, first published in 2006, takes a developmental approach to the presentation of our understanding of how vertebrates construct a retina. Written by experts in the field, each of the seventeen chapters covers a specific step in the process, focusing on the underlying molecular, cellular, and physiological mechanisms. There is also a special section on emerging technologies, including genomics, zebrafish genetics, and stem cell biology that are starting to yield important insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise view of vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book will also be attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.
Download or read book Noninvasive Testing of Intrinsic Photosensitive Retinal Ganglion Cells written by Bastian Fersch and published by . This book was released on 2016-10-04 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
