Download or read book Understanding Population Genetics written by Torbjörn Säll and published by John Wiley & Sons. This book was released on 2017-07-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life in all its improbable and amazing richness one must start by understanding population genetics.
Download or read book Understanding Population Genetics written by Torbjörn Säll and published by John Wiley & Sons. This book was released on 2017-09-25 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life – in all its improbable and amazing richness – one must start by understanding population genetics.
Download or read book Human Population Genetics and Genomics written by Alan R. Templeton and published by Academic Press. This book was released on 2018-11-08 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now
Download or read book Introduction to Population Genetics written by Richard Halliburton and published by Pearson. This book was released on 2004 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics.
Download or read book Population Genetics written by Matthew B. Hamilton and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
Download or read book Understanding Population Genetics written by Torbj Rn S LL and published by Wiley-Blackwell. This book was released on 2017 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers"--Provided by publisher.
Download or read book Understanding Population Genetics written by Bengt Bengtsson and published by Wiley-Blackwell. This book was released on 2017-07-31 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life ? in all its improbable and amazing richness ? one must start by understanding population genetics.
Download or read book Human Population Genetics written by John H. Relethford and published by John Wiley & Sons. This book was released on 2012-03-27 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf
Download or read book The Foundations of Population Genetics written by Daniel M. Weinreich and published by MIT Press. This book was released on 2023-08-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible but rigorous treatment of the theoretical foundations of population genetics. Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous treatment for advanced undergraduate and graduate students interested in building a quantitative understanding of the genetics of evolution. Existing texts either assume very mathematically advanced readers, or avoid much of the underlying theory, instead focusing on current methods of data analysis. In contrast, The Foundations of Population Genetics develops the theory from first principles. Requiring only confidence in algebra, this self-contained, student-friendly book illustrates the conceptual framework, terminology, and methods of mathematical modeling. It progressively introduces concepts from genetics as needed, while emphasizing biological implications throughout. As a result, readers come away with a deep understanding of the structure of population genetics without needing to master its mathematics. Connects theory with the most recent genetic data better than existing texts Features engaging real-world examples and extensive original figures Provides dozens of carefully scaffolded questions that deepen the reader's understanding of key concepts Ideal as a succinct reference for established scientists in biology, medicine, and computer science Instructor resources available
Download or read book Plant Genetic Conservation written by Nigel Maxted and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent development of ideas on biodiversity conservation was already being considered almost three-quarters of a century ago for crop plants and the wild species related to them, by the Russian geneticist N.!. Vavilov. He was undoubtedly the first scientist to understand the impor tance for humankind of conserving for utilization the genetic diversity of our ancient crop plants and their wild relatives from their centres of diversity. His collections showed various traits of adaptation to environ mental extremes and biotypes of crop diseases and pests which were unknown to most plant breeders in the first quarter of the twentieth cen tury. Later, in the 1940s-1960s scientists began to realize that the pool of genetic diversity known to Vavilov and his colleagues was beginning to disappear. Through the replacement of the old, primitive and highly diverse land races by uniform modem varieties created by plant breed ers, the crop gene pool was being eroded. The genetic diversity of wild species was equally being threatened by human activities: over-exploita tion, habitat destruction or fragmentation, competition resulting from the introduction of alien species or varieties, changes and intensification of land use, environmental pollution and possible climate change.
Download or read book Basic Concepts in Population Quantitative and Evolutionary Genetics written by James Franklin Crow and published by W H Freeman & Company. This book was released on 1986 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Evaluation of Forensic DNA Evidence written by National Research Council and published by National Academies Press. This book was released on 1997-01-12 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Download or read book Population Genetics and Microevolutionary Theory written by Alan R. Templeton and published by John Wiley & Sons. This book was released on 2006-09-29 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Download or read book Population Genetics with R written by Áki Jarl Láruson and published by Oxford University Press. This book was released on 2021-02-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Population genetics is an inherently quantitative discipline, yet often focuses upon abstract concepts which can be difficult to conceptualize and appropriately visualize at first glance. This book focuses on applying the hugely popular R software specifically to the field, offering an accessible, step-by-step guide to tackling the challenges of achieving effective data interpretation and summary. The authors adopt an engaging "learning by doing" approach that will enable readers to develop an intuitive understanding of key population genetics concepts through the use of R. Beginning with the groundwork of installing and using R (including CRAN and the RStudio IDE), the book works through the use of basic commands for data manipulation. An introduction to basic terminology in population genetics follows, clearly explaining how these fundamental assumptions can provide insights and form basic inferences for real populations. The focus then moves onto statistical tests including writing and running algorithms as functions. Subsequent chapters examine genetic variation, adaptation, and natural selection as well as different approaches to population differences. Importantly, the accompanying set of practical exercises demonstrate that implementing all of these concepts via programming can actually help greatly in understanding them, even if they may at first seem insurmountably complex. Finally, this accessible textbook points the way forwards to other key concepts that are important to understanding modern day population genetics research (in particular coalescent theory) and offers the reader useful launching points for further learning. Population Genetics with R is aimed at students ranging from undergraduate to postgraduate level in the fields of population genetics, ecology, evolutionary biology, conservation genetics, computational biology, and biostatistics.
Download or read book Information Geometry and Population Genetics written by Julian Hofrichter and published by Springer. This book was released on 2017-02-23 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.
Download or read book Population Genetics written by John H. Gillespie and published by . This book was released on 1998 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In a species with a million individuals," writes John H. Gillespie, "it takes roughly a million generations for genetic drift to change allele frequencies appreciably. There is no conceivable way of verifying that genetic drift changes allele frequencies in most natural populations. Our understanding that it does is entirely theoretical. Most population geneticists are not only comfortable with this state of affairs, but revel in the fact that they can demonstrate on the back of an envelope, rather than in the laboratory, how an important evolutionary force operates." Longer than the back of an envelope but more concise than many books on the subject, this brief introduction to the field of population genetics offers students and researchers an overview of a discipline that is of growing importance. Chapter topics include genetic drift; natural selection; non-random mating, quantitative genetics; and the evolutionary advantage of sex. While each chapter treats a specific topic or problem in genetics, the common thread throughout the book is what Gillespie calls "the main obsession of our field," the recurring question, "Why is there so much genetic variation in natural populations?" "Population genetics remains the central intellectual connection between genetics and evolution. As genetics becomes integral to all aspects of biology, the unifying nature of evolutionary studies rests more and more on population genetics. This book lays out much of the foundation of population genetics augmented with interesting particulars and conceptual insight. Population genetics involves ideas that are quantitative and often difficult for biology undergraduates, but Professor Gillespie offershis characteristically clear thinking and articulate explanations." -- Charles Langley, University of California-Davis
Download or read book Principles of Population Genetics written by Daniel L. Hartl and published by Sinauer Associates Incorporated. This book was released on 2007 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.
