Download or read book Twelfth Interim Report of the Subcommittee on Acute Exposure Guideline Levels written by National Research Council and published by National Academies Press. This book was released on 2005-02-03 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances (EHSs), as defined in the Superfund Amendments and Reauthorization Act of 1986, can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars or trucks used in transporting these substances, or intentionally through terrorist activities. It is also feasible that these substance can be released by improper storage and/or handling. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental and intentional releases. This report provides technical guidance on establishing community Acute Exposure Guideline Levels (AEGLs) for certain hazardous chemicals. It reviews the scientific validity of AEGLs developed by the national Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances, identifies research priorities, and identifies guidance issues that may require modification or further development based on the toxicological database for the chemicals reviewed. This twelfth interim report offers recommendations for improving AEGLs for the following 15 chemicals: toluene, xylenes, ammonia, bromine, aniline, methyl ethyl ketone, hydrazine, iron pentacarbonyl, phosphine, chlorine, trifluoride, ethyleneimine, propyleneimine, allyl alcohol, ethylene oxide, and nickel carbonyl.

Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2010-03-18 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.

Download or read book Thirteenth Interim Report of the Subcommittee on Acute Exposure Guideline Levels written by National Research Council and published by National Academies Press. This book was released on 2005-08-01 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formed in 1995 by EPA, several other federal and state agencies, and several private organizations, the National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances (referred to as the NAC) develops, reviews, and approves acute exposure guideline levels (AEGLs) for up to 400 extremely hazardous substances (EHSs). AEGLs have a broad array of potential applications for federal, state, and local governments and for the private sector. They are necessary for prevention and emergency-response planning for potential releases of EHSs, either from accidents or as a result of terrorist activities. This report includes an assessment of the NAC's draft AEGLs documents for the following 10 chemicals: 1, 4-dioxane; chloroform; carbon tetrachloride; sulfur dioxide; cis, trans 1,-2 dichloroethylene; monochloroacetic acid; carbon monoxide; fluorine; methanol; and phenol.

Download or read book Twenty second Interim Report of the Committee on Acute Exposure Guideline Levels written by National Research Council and published by National Academies Press. This book was released on 2013-08-05 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1991, the Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) asked the National Research Council (NRC) to provide technical guidance for establishing community emergency exposure levels for extremely hazardous substances (EHSs) pursuant to the Superfund Amendments and Reauthorization Act of 1986. As a result the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993 and Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances in 2001; providing updated procedures, methods, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels (AEGLs) for hazardous substances for assessing acute adverse health effects. Stemming from this report the NAC has developed AEGLs for at least 270 EHSs. There are currently three AEGLs: AEGL-1, AEGL-2, and AEGL-3. AEGL-1 is the airborne concentration of a substance above which it is predicted that the general population could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. These effects are not disabling and are transient and reversible once exposure is stopped. AEGL-2 is the airborne concentration (of a substance above which it is predicted that the general population could experience irreversible, long-lasting adverse health effects or an impaired ability to escape. AEGL-3 is the airborne concentration of a substance above which it is predicted that the general population could experience life threatening health effects or death. On April 22-24 2013, the NRC-established Committee on Acute Exposure Guideline Levels 2013 met to review AEGL documents approved by the NAC. The committee members were selected for their expertise in toxicology, medicine, industrial hygiene, biostatistics, and risk assessment. Twenty-second Interim Report of the Committee on Acute Exposure Guideline Levels presents a review of AEGLs for various chemicals including acrylonitrile, halogen fluorides, tellurium hexafluoride, and thionyl chloride.

Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2011-10-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances (EHSs)² can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. Acute Exposure Guideline Levels for Selected Airborne Chemicals is the tenth volume of the series and documents for N,N-dimethylformamide, jet propellant fuels 5 and 8, methyl ethyl ketone, perchloromethyl mercaptan, phosphorus oxychloride, phosphorus trichloride, and sulfuryl chloride.

Download or read book Nineteenth Interim Report of the Committee on Acute Exposure Guideline Levels written by Committee on Acute Exposure Guideline Levels and published by National Academies Press. This book was released on 2011-01-27 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present report is the committee's 19th interim report. It summarizes the committee's conclusions and recommendations for improving NAC's AEGL documents for the following chemicals and chemical classes: acrylonitrile, benzonitrile, boron tribromide, BZ (3-quinuclidinyl benzilate), chloroarsenicals, chloroformates, bis-chloromethylether, chloromethylether, chlorosilanes (26 selected compounds), cyanogen, ethyl mercaptan, hexafluoroacetone, lewisites, mercury vapor, nitric acid, nitric oxide, nitrogen dioxide, nitrogen tetroxide, oleum, phenyl mercaptan, propargyl alcohol, selenium hexafluoride, silane, sulfer trioxide, sulfuric acid, tear gas, tert-octyl mercaptan, tetramethoxy silane, thionyl chloride, trimethoxysilane, trimethylbenzenes (1,2,4-; 1,2,5-;and 1,3,5-TMB), and vinyl chloride.

Download or read book Twenty first Interim Report of the Committee on Acute Exposure Guideline Levels written by National Research Council and published by National Academies Press. This book was released on 2012-01-01 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extremely hazardous substances (EHSs) can be released accidentally as a result of chemical spills, industrial explosions, fire, or accidents involving railroad cars or trucks transporting EHSs, or they can be released intentionally through terrorist activities. These substances can also be released by improper storage or handling. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental or intentional releases. As part of its efforts to develop acute exposure guideline levels for EHSs, the Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001. It provided updated procedures, methods, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels (AEGLs) in considering acute adverse health effects to develop AEGL values. Using both these reports, the NAC-consisting of members from the EPA, the Department of Defense (DOD), the Department of Energy (DOE), the Department of Transportation (DOT), other federal and state governments, the chemical industry, academia, and other organizations from the private sector-developed AEGLS for approximately 270 EHSs. Twenty-First Interim Report of the Committee on Acute Exposure Guideline Levels: Part A summarizes the committee's conclusions and recommendations for improving AEGL documents for several chemicals and chemical classes.

Download or read book Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals written by National Research Council and published by National Academies Press. This book was released on 2001-06-25 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routesâ€"both oral and dermalâ€"as well as risk assessors in the government, academe, and private industry.

Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2003-05-15 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report reviews documents on acute exposure guideline levels (AEGLs) for nerve agents GA (tabun), GB (sarin), GD (soman), GD, and VX, sulfur mustard, diborane, and methyl isocyanate. The documents were developed by the National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Chemicals (NAC). The subcommittee concludes that the AEGLs developed in those documents are scientifically valid conclusions based on data reviewed by NAC and are consistent with the NRC reports on developing acute exposure guideline levels.

Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2008-09-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the sixth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts.

Download or read book WHO global air quality guidelines written by Weltgesundheitsorganisation and published by World Health Organization. This book was released on 2021-09-07 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main objective of these updated global guidelines is to offer health-based air quality guideline levels, expressed as long-term or short-term concentrations for six key air pollutants: PM2.5, PM10, ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. In addition, the guidelines provide interim targets to guide reduction efforts of these pollutants, as well as good practice statements for the management of certain types of PM (i.e., black carbon/elemental carbon, ultrafine particles, particles originating from sand and duststorms). These guidelines are not legally binding standards; however, they provide WHO Member States with an evidence-informed tool, which they can use to inform legislation and policy. Ultimately, the goal of these guidelines is to help reduce levels of air pollutants in order to decrease the enormous health burden resulting from the exposure to air pollution worldwide.

Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.

Download or read book Acute Exposure Guideline Levels for Selected Airborne Chemicals written by National Research Council and published by National Academies Press. This book was released on 2012-04-29 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the request of the Department of Defense and the Environmental Protection Agency, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for several chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies, such as accidental or intentional chemical releases in community, workplace, transportation, and military settings, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. This volume in the series includes AEGLs for bis-chloromethyl ether, chloromethyl methyl ether, chlorosilanes, nitrogen oxides, and vinyl chloride.

Download or read book Toxicological Profile for Chloromethane written by and published by . This book was released on 1998 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicological Profile for Nitrophenols written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicological Profile for Lead written by and published by . This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: