Download or read book Translational Sports Medicine written by Adam Eltorai and published by Elsevier. This book was released on 2023-08-14 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Sports Medicine covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. This title is an indispensable tool in grant writing and funding efforts with its practical, straightforward approach that will help aspiring investigators navigate challenging considerations in study design and implementation. It provides valuable discussions of the critical appraisal of published studies in translational sports medicine, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or sports medicine clinician who has ever had a good clinical idea but not the knowledge of how to test it. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational sports medicine, and know what is needed in collaboration. Focuses on the principles of evidence-based medicine and applies these principles to translational investigations within sports medicine Details discussions of the critical appraisal of published studies in translational sports medicine, supporting evaluation with respect to measuring outcomes and making effective use of all types of evidence in patient care Written by experts in the sports medicine field

Download or read book Translational Informatics written by Bairong Shen and published by Springer Nature. This book was released on 2022-04-22 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides readers the informatics and data-driven models for the discovery of personalized excise prescriptions applied to different cases. Overdiagnosis or over-treatment often happened since the complex interaction among the lifestyle, genetic, and environmental factors. Sports and exercise are reported efficient to prevent or reduce the risk of diseases, but the interactions between sports/exercise and disease are personalized and complex. Translational informatics is a powerful paradigm and it promotes the transfer of big data, knowledge and models to the precision application of sports to prevent diseases. Sports and exercise may have different effects on diverse diseases including cancers, neurodegenerative disease, and cardiovascular diseases, etc. This book covers many modern informatics models such as ontologies, knowledge graphs, blockchain, participatory medicine, semantic artificial intelligence, big data modeling, and so on. It also describes the challenges for the sports and exercise medical data sharing and standardization, the privacy protection of data as well as the integration of data from genomic level to physiological phenotype level. This book will be helpful to the readers who are interesting in sports and exercise medicine, healthcare, big data modeling, artificial intelligence in medicine and healthcare.

Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Download or read book Sports Medicine written by and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Download or read book Encyclopedia of Sports Medicine written by Lyle J. Micheli and published by SAGE. This book was released on 2010-11-17 with total page 1881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entries cover issues related to sports medicine, including diagnostic and treatment techniques, conditioning and training, diet and nutrition, doping and performance enhancement, injury prevention, and career opportunities.

Download or read book Key Topics in Sports Medicine written by A.A. Narvani and published by Routledge. This book was released on 2006-09-27 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Students have often commented on the need for a concise textbook on sports medicine that presents the essential information otherwise scattered across several much larger medical textbooks on other topics. Addressing this need, Key Topics in Sports Medicine makes effective use of the successful Key Topics format to provide extensive relevant information in an accessible and easy-to-follow manner. Practical and clearly presented, this is an invaluable resource for those students and practioners of sports medicine and rehabilitation, athletic training, physiotherapy and orthopedic surgery.

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Download or read book Translational Medicine Tools And Techniques written by Aamir Shahzad and published by Academic Press. This book was released on 2015-11-24 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. The book also addresses regulatory processes in USA, EU, Japan and China. By providing details on omics sciences techniques, biomarkers, data mining and management approaches, case reports from industry, and tools to assess the value of different technologies and techniques, this book is the first to provide a user-friendly go-to guide for key opinion leaders (KOLs), industry administrators, faculty members, clinicians, researchers, and students interested in translational medicine. Includes detailed and standardized information about the techniques and tools used in translational medicine Provides specific industry case scenarios Explains how to use translational medicine tools and techniques to plan and improve infrastructures and capabilities while reducing cost and optimizing resources

Download or read book Clinical and Translational Science written by David Robertson and published by Academic Press. This book was released on 2016-11-25 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Download or read book ACSM s Primary Care Sports Medicine written by Douglas McKeag and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by internationally known experts in primary care sports medicine, this book is the most comprehensive sports medicine reference geared to primary care practitioners. It is the ideal text for physicians studying for the Certificate of Added Qualifications in Sports Medicine that is now offered in many disciplines including family practice, internal medicine, emergency medicine, pediatrics, physical medicine and rehabilitation, and osteopathic medicine. This revised and updated Second Edition is published in association with the American College of Sports Medicine, and includes more practical information. The new, more user-friendly format features numerous illustrations, charts, and tables, including full-color illustrations.

Download or read book Sports Medicine written by and published by . This book was released on 2021 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nonsurgical Sports Medicine written by N. Nichole Barry and published by JHU Press. This book was released on 2003-04-30 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a growing number of people, young and old, engaged in a variety of physical activities, the field of sports medicine has gained greater importance for medical professionals. Nonsurgical Sports Medicine provides a comprehensive guide for the physician whose practice includes preparing patients to take part in sports as well as diagnosing and treating any resulting injuries. Nonsurgical Sports Medicine begins with an overview of the principles of the preparticipation medical evaluation and outlines how preexisting medical conditions may be optimally managed in the athlete. Individual chapters cover the evaluation and treatment of head and spine injuries, injuries to the upper and lower extremities, and overuse syndromes. The book also addresses such important issues as infectious diseases, ergogenic agents, the needs of older and young athletes, women in sports, and the effect of environmental conditions on athletes. Along with detailed discussions of the anatomy and physiology of the musculoskeletal system, the authors describe specific maneuvers during the physical examination which are important for evaluation and diagnosis. Nonsurgical Sports Medicine provides a broad range of information that complements a physician's general knowledge and that will be invaluable in assessing patients with sports-related injuries.

Download or read book Sports Medicine Consult written by Brian D. Busconi and published by Lippincott Williams & Wilkins. This book was released on 2009 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides clinicians treating athletes at the point of care with concise, practical keys to evaluation and functional treatment of sports-related problems. It is organized by chief complaint and guides clinicians to a rational differential diagnosis, a thorough history and physical exam, appropriate diagnostic testing, an accurate diagnosis, a sports-specific treatment plan, and safe return-to-play recommendations. Bulleted sections, icons, and a uniform layout help readers quickly find key information to make a diagnosis, order tests, initiate treatment, recognize indications for referral, and identify red flags. Appendices describe injection techniques and detail progressive return-to-play programs for throwing and running athletes.

Download or read book Translational Control in Biology and Medicine written by Michael Mathews and published by CSHL Press. This book was released on 2007 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.

Download or read book The Olympic Textbook of Medicine in Sport written by Martin P. Schwellnus and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive new volume in the Encyclopaedia of SportsMedicine series, published under the auspices of the InternationalOlympic Committee, delivers an up-to-date, state of the artpresentation of the medical conditions that athletes may sufferfrom during training and competition. Presented in a clear style and format, The Olympic Textbookof Medicine in Sport, covers not only the basic approach totraining, monitoring training and the clinical implications ofexcessive training, but also deals with all the major systems inthe body, and focuses on medical conditions that athletes maysuffer from in each system. Medical conditions in athletes withdisabilities, genetics and exercise and emergency sports medicineare also uniquely examined. The Olympic Textbook of Medicine in Sport draws on theexpertise of an international collection of contributors who arerecognized as leaders in their respective fields. The systematic approach followed in the book will make itinvaluable to all medical doctors and other health personnel whoserve athletes and sports teams. Sports practitioners are providedwith a clinical approach to the prevention, diagnosis and treatmentof common and less common medical problems encountered by athletes.This volume should be kept close at hand for frequentconsultation.

Download or read book Essentials of Primary Care Sports Medicine written by Gregory L. Landry and published by Human Kinetics. This book was released on 2003 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a non-orthopedic approach to sports medicine that will help athletic trainers, sports therapists, physicians, and health practitioners focus on athletes' general health issues. Readers will be able to understand the primary care concerns of athletes, earn their trust, and work more effectively with them