Download or read book Translational Cancer Research for Surgeons An Issue of Surgical Oncology Clinics written by William G. Cance and published by Elsevier Health Sciences. This book was released on 2013-10-28 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIST, melanoma, colorectal cancer, breast cancer, and endocrine cancer.
Download or read book Translational Research in Surgical Oncology written by and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational Research in Breast Cancer written by Dong-Young Noh and published by Springer Nature. This book was released on 2021-05-13 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
Download or read book Translational Research in Surgical Oncology an Issue of Surgical Oncolgy Clinics written by Benjamin Li and published by Saunders. This book was released on 2008-04-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue will include three general articles on translational research in surgical oncology (genomic/expression profile in predicting cancer outcomes, target-specific therapy in solid tumors, molecular pathology) and nine articles on translational research in specific organ sites (melanoma, colorectal cancer, breast, Gastric, lung, MEN, pancreatic, neuroendocrine and liver)
Download or read book The Role of Genetic Testing in Surgical Oncology An Issue of Surgical Oncology Clinics of North America written by Thomas K. Weber and published by Elsevier Health Sciences. This book was released on 2016-01-07 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Oncology Clinics of North America, edited by Thomas Weber, MD, is devoted to Genetic Testing in Surgical Oncology. Articles in this issue include: The Critical Importance of Timely Genetic Testing; Securing and Documenting Cancer Family History in the Age of the Electronic Medical Record; Cancer Family Registries: Vital Tools for Patient Management and Cancer Genetics Translational Research; The Genetics of Breast Cancer; The Genetics of Colorectal Cancer: HNPCC, FAP MYH, and Hamartomatous Syndromes Including Peutz-Jeghers and Jevenile Polyposis; Hereditary Gastric Cancer Syndromes; Hereditary Pancreatic Cancer Syndromes; Hereditary Melanoma: Genetics and Multidisciplinary Management; Multiple Endocrine Neoplasia: Genetics and Clinical Management; Sequence Variants of Uncertain Significance (VUS): What To Do When Genetic Testing Results Are Not Definitive; Confidentiality and the Risk of Genetic Discrimination: What Surgeons Need to Know; and A Certified Genetic Counselor: A Crucial Clinical Resource in the Management of Patients with Suspected Hereditary Solid Tumor Syndromes.
Download or read book Targeted Therapy in Translational Cancer Research written by Apostolia-Maria Tsimberidou and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Download or read book Translational Pancreatic Cancer Research written by Christoph W. Michalski and published by Springer Nature. This book was released on 2020-07-31 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer and stromal, epigenetic and metabolism targeting as promising approaches to be translated into early phase clinical trials. Chapters within this part also deal with approaches that are close to being implemented in clinical practice or are already being tested in (early) clinical trials, such as those that targeting the immune systems and strategies to overcome immunotherapy resistance; phase 1 clinical trials and translational approaches in surgical treatment. Written by experts in their fields, Translational Pancreatic Cancer Research provides an outlook towards future directions by integrating information both from basic and clinical research and though demonstrating pathways to better understanding pancreatic cancer and current approaches to translating these into clinical practice.
Download or read book Immunotherapy in Translational Cancer Research written by Laurence J. N. Cooper and published by John Wiley & Sons. This book was released on 2018-05-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.
Download or read book Clinical Trials in Surgical Oncology An Issue of Surgical Oncology Clinics of North America E Book written by Elin R. Sigurdson and published by Elsevier Health Sciences. This book was released on 2017-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Elin R. Sigurdson, is devoted to Clinical Trials in Surgical Oncology. Dr. Sigurdson has assembled expert authors to review the following topics: Commentary on Randomized Controlled Trials; Randomized Clinical Trials in Soft Tissue Sarcoma; Randomized Clinical Trials in Gastrointestinal Stromal Tumors; Randomized Clinical Trials in Melanoma; Randomized Clinical Trials in Breast Cancer; Randomized Clinical Trials in Gastroesophageal Carcinoma; Randomized Clinical Trials in Hepatocellular Carcinoma; An Update on Randomized Clinical Trials in Advanced and Metastatic Colorectal Carcinoma; Randomized Clinical Trials in Colon and Rectal Cancer; Randomized Clinical Trials in Anal Cancers; The Elderly in Randomized Clinical Trials; Hereditary Syndromes in Clinical Trials; Future Clinical Trials: Genetically Driven Trials; Randomized Clinical Trials in Neuroendocrine Tumors, and more!
Download or read book Translational Research in Cancer written by Sivapatham Sundaresan and published by BoD – Books on Demand. This book was released on 2021-02-03 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer
Download or read book Personalized Treatment of Breast Cancer written by Masakazu Toi and published by Springer. This book was released on 2016-05-24 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.
Download or read book Clinical Scenarios in Surgical Oncology written by Vijay P. Khatri and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique case-based review of surgical oncology offers excellent preparation for oral board examinations, which emphasize both general knowledge and case management. The book presents 91 cases structured to reflect the surgeon's decision-making process. Each case begins with a patient presentation and imaging studies or pathology results and proceeds through a series of decision points—differential diagnosis, requests for additional tests, diagnosis, surgical approach, discussion of potential pitfalls, and follow-up. Cases are grouped by organ system and each section ends with a treatment algorithm summarizing the decision points. Nearly 400 radiologic images and other relevant illustrations accompany the text.
Download or read book Disparities and Determinants of Health in Surgical Oncology An Issue of Surgical Oncology Clinics of North America E Book written by Oluwadamilola “Lola Fayanju and published by Elsevier Health Sciences. This book was released on 2021-11-18 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Surgical Oncology Clinics, guest editor Oluwadamilola "Lola" Fayanju brings considerable expertise to the topic of Disparities and Determinants of Health in Surgical Oncology. Provides in-depth, clinical reviews on the latest updates on Disparities and Determinants of Health in Surgical Oncology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
Download or read book Textbook of Surgical Oncology written by Graeme J. Poston and published by CRC Press. This book was released on 2007-11-15 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgery alone cures more than 60% of those patients whose cancer are amenable to curative treatment. Surgical oncology is not universally accepted as a unified discipline worldwide. There are many reasons for this situation, including the drive to anatomic site specialization, but also the need to provide comprehensive 'general' surgical provision to more isolated and rural communities. Textbook of Surgical Oncology, written by a highly acclaimed list of international authors, comprehensively covers the role of the surgical oncologist in the management of patients with solid tumors. This book provides a state of the art review of cancer surgery for senior residents approaching certification at the completion of their training as well as providing an up to date reference work for established clinicians in their day to day practice, including those in general surgery, surgical oncology, urologists, gynecologists, thoracic, neurosurgical, radiation oncologist and medical oncologists.
Download or read book Cancer Clinical and Translational Research written by Lydia Doyle and published by . This book was released on 2020-09-08 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer refers to a family of diseases, which involves an abnormal growth of cells that can invade or spread to other parts of the body. Survival rates in people suffering from cancer vary according to the cancer type and stage in which it is diagnosed. The prognosis is worse for cancers that have metastasized. Cancer survivors often develop a second primary cancer. Cancer research strives to identify possible causes and strategies for the prevention, diagnosis and treatment of cancer. It involves various aspects of molecular bioscience, cancer epidemiology and clinical trials for evaluating and comparing outcomes of different cancer therapies. Translational research in cancer seeks to understand the mechanisms of cancer development and progression, and translate such scientific findings into formulating approaches in the treatment and prevention of cancer. Clinical cancer research is devoted to the development of surgical procedures, pharmaceutical agents and medical technologies for the treatment of cancer. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of cancer management. The topics covered herein deal with the clinical and translational research in the field of oncology. For all readers who are interested in this field, the case studies included herein will serve as an excellent guide to develop a comprehensive understanding.
Download or read book Current Controversies in Cancer Care for the Surgeon written by Katherine A. Morgan and published by Springer. This book was released on 2015-12-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, major advances have occurred in the management of the many fields of cancer treatment encountered by the general surgeon. These developments have evolved from improved understanding of disease biology, high level clinical outcomes studies, as well as translational research with new available therapies. These advances have brought major changes to cancer care and have surfaced new dilemmas in clinical decision-making. Modern cancer management requires an understanding of the current status of a diverse array of oncologic diseases. Current Controversies in Cancer Care for the Surgeon provides a comprehensive update on the management of various cancers as interpreted by recognized experts in the field. In addition, each chapter will focus on current controversies and areas of advance. The text is designed to assist the practicing surgeon in achieving optimal management of encountered oncologic problems. Such an inclusive text will be invaluable resource for clinical surgeons, surgeons in training, students and researchers.
Download or read book ESMO Handbook on Principles of Translational Research written by Håkan Mellstedt and published by CRC Press. This book was released on 2007-05-21 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using state-of-the-art and evidence-based literature references and reviews, the authors present an overview of translational research that is both reliable and easily understood. The book begins with principles of normal cell biology and normal immunology. It examines tumor biology and basic tumor immunology. It then discusses limitless replicativ
