Download or read book Translational Research and Discovery in Gastroenterology written by Deborah L. Gumucio and published by John Wiley & Sons. This book was released on 2014-05-23 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Gastroenterology: Organogenesis to Disease bridges the gap between basic and clinical research by providing information on GI (gastrointestinal) organ development discovered through scientific inquiry, alongside clinical observations of acquired and congenital abnormalities. Paired chapters, written from basic science and clinical viewpoints, review the major biological pathways and molecules at work in organ ontogeny and disease. In addition to a comprehensive survey of GI organ development and pathologies, the book also highlights model organisms and new areas of research, with chapters devoted to recent advances in the field of GI stem cell biology, and the potential for tissue engineering of GI organs. The topics covered provide a unique window onto current activity in the field of gastroenterology, fostering enhanced knowledge for developmental biologists as well as for clinical practitioners. Notable features include the following: • Basic science chapters review the molecular and cellular pathways of GI organ development alongside clinical chapters examining organ-based diseases, closing the gap between the bench and the clinic. • Derivative organs – esophagus, stomach, pylorus, small intestine, colon, liver, and pancreas –as well as tissues such as serosa and enteric nervous system that are common to multiple GI organs. • Chapters detailing the use of model organisms – Drosophila, sea urchin, zebrafish, C. elegans, Xenopus – for basic discovery studies are included. • Chapters on GI stem cells and the potential for tissue engineering of the GI organs provide a view to the future of research and therapy in these organs.

Download or read book Development Differentiation and Disease of the Luminal Gastrointestinal Tract written by and published by Academic Press. This book was released on 2010-12-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract reviews the latest research and developments in this field. - Discusses new discoveries, approaches, and ideas - Contributions from leading scholars and industry experts - Includes reference guide for researchers involved in molecular biology and related fields

Download or read book Translational Gastroenterology written by Adam E.M. Eltorai and published by Academic Press. This book was released on 2025-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

Download or read book Peptide Drug Discovery and Development written by Miguel Castanho and published by John Wiley & Sons. This book was released on 2011-10-24 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.

Download or read book Clinical and Translational Research Studies in Gastrointestinal Motility and Functional Disorders written by Michael Camilleri and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Discoveries in Gastroenterology written by Gyula Mózsik and published by Akademiai Kiado. This book was released on 2006 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this book have played an essential role in presenting Hungarian clinical research to the world. Their pioneering activities have been recognized by the University of Pecs (Hungary), giving them the title of Honoris Causa Doctors. All have worked in the field of gastroenterology - in Japan, the UK, the US, and Hungary. This volume includes the following research essays: Novel Agents for the Control of Secretory Diarrhea; Molecular Pharmacology and Biochemistry of Gastroduodenal Mucosal Damage and Protection; On the Advances of Gastric Ulcer Studies in Experimental Animals Over the Past 40 Years; The Discovery and Development of Anti-Inflammatory Analgesic Drugs; Why Gastrointestinal Ulcers Develop and Do Not Heal; Trends in Neurogastroenterology Research; Mucosal Protective Action of Prostaglandin E2 in the Alimentary Tract and EP Receptor Subtypes.

Download or read book Translational Systems Medicine and Oral Disease written by Stephen T. Sonis and published by Academic Press. This book was released on 2019-09-14 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. - Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine - Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases - Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader - Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Download or read book Encyclopedia of Gastroenterology written by and published by Academic Press. This book was released on 2019-11-06 with total page 3420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Gastroenterology, Second Edition provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included. Presents comprehensive coverage of every topic within gastroenterology Offers researchers a one-stop, fully-referenced resource to explore questions Includes teaching tools, multimedia and interactive elements Provides readers with multi-layered content and a media-rich learning resource for both instructors and students Covers hot new topics in GI health and disease, including new sections on stem cells, intestinal bacteria, obesity and intestinal microbiota

Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

Download or read book Translational Biotechnology written by Yasha Hasija and published by Academic Press. This book was released on 2021-02-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Download or read book The American Journal of Digestive Diseases written by and published by . This book was released on 1915 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gastrointestinal Diseases and Their Associated Infections written by Guy D. Eslick and published by Elsevier Health Sciences. This book was released on 2019-01-17 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians. - Covers infections associated with gastroesophageal reflux disease and Barrett's esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn's Disease, and more. - Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer. - Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections. - Consolidates today's available information on this timely topic into a single convenient resource.

Download or read book Biomedical Translational Research written by R.C. Sobti and published by Springer Nature. This book was released on 2022-06-14 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.

Download or read book Translational Research in Cancer written by Sivapatham Sundaresan and published by BoD – Books on Demand. This book was released on 2021-02-03 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer

Download or read book Frontiers in Oncology Quarterly Highlights Quarter 1 2019 written by Giuseppe Giaccone and published by Frontiers Media SA. This book was released on 2019-07-01 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foreword from the Field Chief Editor, Giuseppe Giaccone Once again Frontiers in Oncology has started the year on a positive note, breaking previous records for submissions and publications, as well as the number of Research Topic article collections posted. The journal continues to grow in size, adding an 18th section focusing on Cancer Metabolism, led by Michael Lisanti and Ubaldo Martinez-Outschoorn, and has brought on a total of five new Chief Editors. Here, introducing Frontiers in Oncology: Quarterly Highlights, we feature a collection of carefully selected articles published during the first quarter of 2019 across the different sections. With a record number of papers to choose from, the papers enclosed in this Special Edition highlight some of the recent advances across the different disciplines. With an array of papers looking at everything from translational research to association studies and clinical trial results, Frontiers in Oncology continues to publish high-quality research from researchers around the world. Many of the recently posted Research Topics in the journal focus on early diagnosis and prevention, as well as the importance of survivorship studies and outcomes of cancer treatment. Consideration of such aspects of cancer research and treatment is pivotal in the global effort towards increased survival rates and improved quality of life. With ASCO 2019 marking the end of Q1 and the transition into Q2, the journal looks forward to the rest of the year, and continuing to play an active role in the research community. Giuseppe Giaccone

Download or read book The use of large animal models to improve pre clinical translational research written by Mark Gray and published by Frontiers Media SA. This book was released on 2023-03-30 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inflammatory Bowel Diseases New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory Bowel Diseases: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Inflammatory Bowel Diseases: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Inflammatory Bowel Diseases: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.