Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Download or read book Neural Circuits and Networks written by Vincent Torre and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of parallel processing and of the mechanisms underlying neural networks in the brain is certainly one of the most challenging problems of contemporary science. During the last decades significant progress has been made by the combination of different techniques, which have elucidated properties at a cellular and molecular level. However, in order to make significant progress in this field, it is necessary to gather more direct experimental data on the parallel processing occurring in the nervous system. Indeed the nervous system overcomes the limitations of its elementary components by employing a massive degree of parallelism, through the extremely rich set of synaptic interconnections between neurons. This book gathers a selection of the contributions presented during the NATO ASI School "Neuronal Circuits and Networks" held at the Ettore Majorana Center in Erice, Sicily, from June 15 to 27, 1997. The purpose of the School was to present an overview of recent results on single cell properties, the dynamics of neuronal networks and modelling of the nervous system. The School and the present book propose an interdisciplinary approach of experimental and theoretical aspects of brain functions combining different techniques and methodologies.

Download or read book Synthesis of Best Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.

Download or read book Health and Social Effects of Nonmedical Cannabis Use The written by World Health Organization and published by World Health Organization. This book was released on 2016-03-15 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cannabis is globally the most commonly used psychoactive substance under international control. In 2013 an estimated 181.8 million people aged 15-64 years used cannabis for nonmedical purposes globally (UNODC 2015). There is an increasing demand for treatment for cannabis-use disorders and associated health conditions in high- and middle-income countries. This report focuses on nonmedical use of cannabis building on contributions from a broad range of experts and researchers from different parts of the world. It aims to present current knowledge on the impact of nonmedical cannabis use on health from its impact on brain development to its role in respiratory diseases. The potential medical utility of cannabis - including the pharmacology toxicology and possible therapeutic applications of the cannabis plant - is outside the scope of this report.

Download or read book Medicating Modern America written by Andrea Tone and published by NYU Press. This book was released on 2007-01-08 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Americans paying more than $200 billion each year for prescription pills, the pharmaceutical business is the most profitable in the nation. The popularity of prescription drugs in recent decades has remade the doctor/patient relationship, instituting prescription-writing and pill-taking as an integral part of medical practice and everyday life. Medicating Modern America examines the meanings behind this pharmaceutical revolution through the interconnected histories of eight of the most influential and important drugs: antibiotics, mood stabilizers, hormone replacement therapy, oral contraceptives, tranquilizers, stimulants, statins, and Viagra. All of these drugs have been popular, profitable, influential, and controversial, and the authors take a historical approach to studying their development, prescription, and consumption. This perspective locates the histories of prescription medicines in specific cultural contexts while revealing the extent to which contemporary debates about pharmaceutical drugs echo concerns voiced by Americans in the past. Exploring the rich and multi-faceted history of pharmaceutical drugs in the United States, Medicating Modern America unveils the untold stories behind America's pharmaceutical obsession. Contributors include: Robert Bud, Jennifer R. Fishman, Jeremy A. Greene, David Healy, Suzanne White Junod, Ilina Singh, Andrea Tone, and Elizabeth Siegel Watkins.

Download or read book Seminars in Addiction Psychiatry written by Ed Day and published by Cambridge University Press. This book was released on 2021-11-04 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of the theory, practical understanding and management of the psychiatric aspects of drug and alcohol use and dependence.

Download or read book The Environmental Science of Drinking Water written by Patrick Sullivan and published by Elsevier. This book was released on 2005-08-01 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: In today's chemically dependent society, environmental studies demonstrate that drinking water in developed countries contains numerous industrial chemicals, pesticides, pharmaceuticals and chemicals from water treatment processes. This poses a real threat. As a result of the ever-expanding list of chemical and biochemical products industry, current drinking water standards that serve to preserve our drinking water quality are grossly out of date. Environmental Science of Drinking Water demonstrates why we need to make a fundamental change in our approach toward protecting our drinking water. Factual and circumstantial evidence showing the failure of current drinking water standards to adequately protect human health is presented along with analysis of the extent of pollution in our water resources and drinking water. The authors also present detail of the currently available state-of-the-art technologies which, if fully employed, can move us toward a healthier future.* Addresses the international problems of outdated standards and the overwhelming onslaught of new contaminants. * Includes new monitoring data on non-regulated chemicals in water sources and drinking water.* Includes a summary of different bottled waters as well as consumer water purification technologies.

Download or read book Small Animal Clinical Pharmacology written by Jill E. Maddison and published by Elsevier Health Sciences. This book was released on 2008 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text

Download or read book ADHD Does not Exist written by Richard Saul and published by Harper Collins. This book was released on 2014-02-18 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this groundbreaking and controversial book, behavioral neurologist Dr. Richard Saul draws on five decades of experience treating thousands of patients labeled with Attention Deficit and Hyperactivity Disorder—one of the fastest growing and widely diagnosed conditions today—to argue that ADHD is actually a cluster of symptoms stemming from over 20 other conditions and disorders. According to recent data from the Centers for Disease Control and Prevention, an estimated 6.4 million children between the ages of four and seventeen have been diagnosed with attention deficit hyperactivity disorder. While many skeptics believe that ADHD is a fabrication of drug companies and the medical establishment, the symptoms of attention-deficit and hyperactivity are all too real for millions of individuals who often cannot function without treatment. If ADHD does not exist, then what is causing these debilitating symptoms? Over the course of half a century, physician Richard Saul has worked with thousands of patients demonstrating symptoms of ADHD. Based on his experience, he offers a shocking conclusion: ADHD is not a condition on its own, but rather a symptom complex caused by over twenty separate conditions—from poor eyesight and giftedness to bipolar disorder and depression—each requiring its own specific treatment. Drawing on in-depth scientific research and real-life stories from his numerous patients, ADHD Does not Exist synthesizes Dr. Saul's findings, and offers and clear advice for everyone seeking answers.

Download or read book Roy and Fraunfelder s Current Ocular Therapy written by Frederick Hampton Roy and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to be concise with a consistent format so that the clinician can focus on a specific area. This edition has had major modifications and embraces evidence-based medicine. The format includes the CPT codes for billing purposes, short description of the condition, etiology/incidence, course/prognosis, laboratory findings, differential diagnosis; prophylaxis, treatment (local and systemic, surgical or other), miscellaneous (names and addresses of support groups) and key references. Incorporates evidence-based medicine so you feel confident that you're formulating the best treatment plans for your patients.Color photos allow you to read about and actually see a picture of select disease entities.Clear, concise format can be photocopied and distributed to patients in some cases, reducing your time spent explaining problems to patients and caregivers.

Download or read book National Survey on Drug Abuse written by and published by . This book was released on 1983 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Magic Molecules written by Susan Aldridge and published by Cambridge University Press. This book was released on 1998-09-28 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of us are drug users, in the broadest sense of the word. Drugs can be medicines, they can be used for pleasure, and they can also be used to protect our long-term health. It is important that we are well informed about the drugs we use - how they work, their benefits and their risks. This book is a unique guide for the general science reader to the drugs of everyday life - from the main types of medicine through to recreational drugs and food supplements. It looks at how drugs interact with their targets in the body, where they come from, how they are developed and what drugs to expect in the future. All the major pharmaceutical medicines are reviewed - painkillers, antibiotics, anti-cancer drugs, anti depressants, heart drugs, tranquillizers and hormones. However this book is much more than a consumer handbook - it also conveys the fascinating science of drug discovery in an easily accessible way.

Download or read book Salivary Bioscience written by Douglas A. Granger and published by Springer Nature. This book was released on 2020-04-07 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.

Download or read book Vertical Flow Constructed Wetlands written by Alexandros Stefanakis and published by Newnes. This book was released on 2014-06-26 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vertical flow constructed wetlands for wastewater and sludge treatment represent a relatively new and still growing technology. Vertical Flow Constructed Wetlands is the first book to present the state-of-the-art knowledge regarding vertical flow constructed wetlands theory and applications. In this book, you will learn about vertical flow systems with information about application and performance. Vertical Flow Constructed Wetlands also includes information on how different countries are applying the technology, with design guidelines to illustrate best practices worldwide. A focus on water conservation through reuse of treated water showcases the benefit of vertical flow construction, which has greatly increased the attractiveness of the technology in recent years. - All state-of-the-art knowledge regarding vertical flow constructed wetlands gathered in one book - A review of various constructed wetland approaches, including information about applications and performance, helps clarify what is currently known about constructed wetland principles and design - Discussion of how to manage the treated wastewater leaving the vertical flow for increasing biodiversity, providing food and habitat for birds, and producing harvestable biomass or crops - Includes case studies of constructed wetlands in developing countries

Download or read book The Diagnosis and Management of Agitation written by Scott L. Zeller and published by Cambridge University Press. This book was released on 2017-02-15 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to the origins and treatment options for agitation, a common symptom of psychiatric and neurologic disorders.