Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2009 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This toxicological profile for perfluoroalkyls was prepared consistent with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA) for the preparation of toxicological profiles. The original guidelines were published in the Federal Register on April 17, 1987. While Perfluoroalkyls are not found on the ATSDR list of Priority Hazardous Substances, ATSDR has determined that a profile for these substances was necessary because data indicate that some perfluoroalkyls are found in the blood of the U.S. general population and in the environment. The agency also determined that it was important to characterize the current available information regarding the health effects from exposure in order to support and inform public health responses and activities by ATSDR and other." -- p. v
Download or read book Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances written by Jamie C. DeWitt and published by Humana Press. This book was released on 2015-04-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.
Download or read book The cost of inaction written by Gretta Goldenman and published by Nordic Council of Ministers. This book was released on 2019-03-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: PFAS (per and polyfluoroalkylsubstances) are known to be extremely difficult to degrade in the environment and to be bioaccumulative and toxic. Exposure to PFAS is suspected to increase the risk of adverse health effects, such as impacts on the thyroid gland, the liver, fat metabolism and the immune system. This study estimates the socioeconomic costs that may result from impacts on human health and the environment from the use of PFAS. Better awareness of the costs and problems associated with PFAS exposure will assist decision-makers and the general public to make more efficient and timely risk management decisions. Findings indicate that the costs are substantial, with annual health-related costs estimated to 2.8 – 4.6 billion EUR for the Nordic countries and 52 – 84 billion EUR for all EEA countries. Overall non-health costs are estimated at 46 million – 11 billion EUR for the Nordic countries.Upon request the excel spreadsheets used for the monetarisation and valuation in this report can also be provided along with a guidance on how to use the estimation of costs for value transfer. Please contact any of the consultants or members of the steering group from the Swedish Chemicals Agency or the Danish Environmental Protection Agency if you are interested in receiving these excel spreadsheets.
Download or read book Toxicological Profile for Bromomethane written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Polyfluorinated Chemicals and Transformation Products written by Thomas P. Knepper and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unparalleled effectiveness and efficiency, polyfluorinated chemicals (PFC) have become essential in numerous technical applications. However, many PFCs brought to market show limited biodegradability, and their environmental persistence combined with toxic and bioaccumulative potential have become a matter of concern in some instances. This volume highlights the synthesis of PFCs, focusing on substances with improved application and environmental properties, which are a challenge for synthetic chemists. Further, modern mass spectrometric techniques for the detection and identification of biotransformation products of PFCs are described. The sorption and leaching behavior of PFC in soil is also addressed in order to predict their fate in the environment. Several contributions discuss the monitoring of PFCs in European surface, ground and drinking waters, treatment options for PFC removal from drinking water, occurrence in food, and the human biomonitoring of PFCs.
Download or read book Toxicological Profile for 1 3 butadiene written by and published by . This book was released on 1992 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Perfluoroalkyl Substances written by Bruno Améduri and published by Royal Society of Chemistry. This book was released on 2022-08-15 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides a balanced overview of the field, from basic synthesis through to applications, why some current PFASs are and may remain the right substance for the job, as well as addressing the challenges and alternatives.
Download or read book Toxicological Profile for Trichloroethylene written by and published by . This book was released on 1997 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Emerging Contaminants Handbook written by Caitlin H. Bell and published by CRC Press. This book was released on 2019-01-15 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term "emerging contaminants" and its multiple variants has come to refer to unregulated compounds discovered in the environment that are also found to represent a potential threat to human and ecological receptors. Such contaminants create unique and considerable challenges as the push to address them typically outpaces the understanding of their toxicity, their need for regulation, their occurrence, and techniques for treating the environmental media they affect. With these challenges in mind, this handbook serves as a primer regarding the topic of emerging contaminants, with current and practical information to help support the goal of protection where they are encountered. Features Explores the definition, identification, and life cycle of emerging contaminants. Reviews current information on sources, toxicology, regulation, and new tools for characterization and treatment of: 1,4-Dioxane (mature in its emerging contaminant life cycle) Per- and polyfluoroalkyl substances (PFASs; a newer group of emerging contaminant) Hexavalent chromium (former emerging contaminant with evolving science) 1,2,3-Trichloropropane (progressing in its emerging contaminant life cycle) Provides thoughts on opportunities in managing emerging contaminants to help balance uncertainty, compress life cycle, and optimize outcomes.
Download or read book Understanding Risk to Wildlife from Exposures to Per and Polyfluorinated Alkyl Substances PFAS written by Mark S. Johnson and published by CRC Press. This book was released on 2021-04-22 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.
Download or read book Toxicity Assessment written by Carlos Manuel Marques Palmeira and published by Humana. This book was released on 2021-03-05 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.
Download or read book Conditioning Agents for Hair and Skin written by Randy Schueller and published by CRC Press. This book was released on 1999-02-02 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing the history, benefits, formulations and future developments of hair and skin conditioning products, this work offers an overview of the subject and unique analysis of the elements of conditioning. It offers the novice chemist a solid foundation of technical knowledge and the seasoned scientist the latest state-of-the-art ingredients and testing procedures used in evaluation.
Download or read book Toxicological Profile for 2 butanone written by and published by . This book was released on 1992 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Per and polyfluorinated substances in the Nordic Countries written by Stefan Posner and published by Nordic Council of Ministers. This book was released on 2013-06-19 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts:1) Identification of relevant per-and polyfluorinated substances and their use in various industrial sectors in the Nordic market by interviews with major players and database information; 2) Emissions to and occurence in the Nordic environment of the substances described in 1); 3) A summary of knowledge of the toxic effects on humans and the environment of substances prioritized in 2); There is a lack of physical chemical data, analystical reference substances, human and environmental occurrence and toxicology data, as well as market information regarding PFCs other than PFOA and PFOS and the current legislation cannot enforce disclosure of specific PFC substance information.
Download or read book Indoor Air Quality written by Hermann Fromme and published by Springer Nature. This book was released on 2023-11-29 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive and detailed overview of indoor pollution, covering the main contaminants in the indoor environment – air and dust, the health aspects of exposure, and different possibilities for a risk assessment. The book outlines the chemical substances and physical and biological factors that occur more frequently indoors, which are of health significance, or for which only limited information on their occurrence indoors is available to date. It also provides guidance to identify where problems may arise in the future and where data is missing for a valid exposure and risk assessment as well as for consequent risk management. Written by a highly recognized and experienced medical expert in the field, the book starts with an introduction to the indoor environment, including topics such as indoor environmental quality and health, indoor climate, sampling of indoor pollutants, and measures to improve indoor air quality. The author then delves into the fundamentals of exposure assessment and special exposure indoor situations, followed by in-depth coverage of the health aspects, and indoor air occurrence of several substances such as volatile organic compounds, very volatile organic compounds, semi-volatile organic compounds, and particulate matters and fibers. Particular attention is given to bioaerosols like mold, microbial volatile organic compounds, mycotoxins, and viruses. Readers will also find chapters devoted to the main health aspects and indoor occurrence of inorganic gases, radon and metals, and smoking. The book closes with a chapter on risk assessment, in which readers will learn more about the basics of risk assessment, key points and processes of a health evaluation, and guidance for assessing indoor air contamination. This book is a unique compilation of the current worldwide exposure situation in private and public indoor spaces, and an important reference for researchers that are willing to assess the rising burden of disease and potential causes behind degraded indoor air quality. Scientists, students, and policymakers interested in the fields of medicine and environmental sciences will understand the appeal of this book.
Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2021 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sampling and Analysis Procedures for Screening of Industrial Effluents for Priority Pollutants written by and published by . This book was released on 1977 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: