Download or read book Total Synthesis of Spongistatin 1 altohyrtin A and Siphonariid Derived Marine Natural Products written by D. Y.-K. Chen and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies Directed Towards the Total Synthesis of Spongistatin 1 altohyrtin A and Pectenotoxin II written by Glenn C. Micalizio and published by . This book was released on 2001 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Total Synthesis of Spongistatin 1 written by D. Y.-K. Chen and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress Towards Total Synthesis of Marine Natural Product Ansalactam A written by Zhanhao Liang and published by . This book was released on 2022 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies Directed Towards the Total Synthesis of Spongistatin 1 written by David Glenn Washburn and published by . This book was released on 1999 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2002 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Total Synthesis of Spongistatins 1 and 2 written by Jason David Katz and published by . This book was released on 2001 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Total Synthesis of the EF Fragment of Spongistatin 1 en Route to a Spongistatin 1 Analog written by Joshua Ross Infantine and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A major goal of the Leighton group is the synthesis of biologically relevant polyketide natural products. Among the most potent and chemically intriguing member of this class is spongistatin 1. This molecule has interested biologists and chemists for more than two decades. In this thesis, we report a highly practical and efficient synthesis of the EF fragment of spongistatin 1. This relied on the rapid introduction of a complex stereochemical array using double cross-metathesis/Sharpless asymmetric dihydroxylation reactions to quickly build the F-ring of spongistatin. The six contiguous stereocenters of the F-ring were established in just five steps. A new one-pot asymmetric strained-silane mediated allylation was developed that was greatly improved over previous methods in regards to practicality and substrate scope. This methodology was used to introduce the sensitive chlorodiene side chain. Finally, completion of the EF fragment led to the synthesis of a spongistatin 1 analog, using our previously developed redesigned ABCD fragment.
Download or read book Total Synthesis of Bioactive Marine Natural Products Inspired by Enolate Chemistry Developments of New Haloalkylations Via Soft Enolizations written by Aaron Thomas Herrmann and published by . This book was released on 2015 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The final part describes a new procedure for the generation of syn-1,3-diols, which addresses both stereo- and regiocontrol in the rhenium catalyzed transposition of allylic alcohols.
