Download or read book Total Knockout written by Taylor Morris and published by Simon and Schuster. This book was released on 2012-03-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: There's nothing ordinary about Lucia Latham - she gets straight A's, she's been middle school Class President for two years running and she's a great boxer - nothing is more fun than a good old sparring match with best friend Cooper, especially since she usually wins. In short, there are few things Lucia tackles that don't turn out exactly how she wants them. So at the beginning of her 8th grade year, Lucia has no reason to believe that things won't continue being easy - until she sticks her foot in her mouth in a HUGE way. Then it seems her carefully constructed world is crashing down around her. Can she regain her super star status or will she be forced to lower her expectations?

Download or read book Total Knockout Fitness written by Martin McKenzie and published by Human Kinetics. This book was released on 2014-01-28 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total Knockout Fitness incorporates a blend of boxing, cardio, and cross-training to produce the ultimate total-body workout. Featuring full-color photos, step-by-step descriptions of exercises and fundamental boxing skills, and a DVD depicting workouts, variations, and training tips, this special package contains everything you need in order to burn calories, increase power and strength, sculpt muscles, and transform your body.

Download or read book The Guide to Investigation of Mouse Pregnancy written by B. Anne Croy and published by Academic Press. This book was released on 2013-12-09 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. - Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications - Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes - Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation - Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success

Download or read book Evolution Emerging Functions and Structure of Actin Binding Proteins written by Lei-Miao Yin and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fatty Acid and Lipotoxicity in Obesity and Diabetes written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and β cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.

Download or read book The Laboratory Mouse written by Hans Hedrich and published by Academic Press. This book was released on 2012-06-14 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. - Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research - Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology - Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Download or read book Brenner and Rector s The Kidney E Book written by Alan S. L. Yu and published by Elsevier Health Sciences. This book was released on 2015-10-25 with total page 3585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification. Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations. Uniform terminology and nomenclature in line with emerging consensus in world kidney community. More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information. Internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors . An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields. The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.

Download or read book Nutrition and Growth written by B. Koletzko and published by Karger Medical and Scientific Publishers. This book was released on 2016-02-25 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a well-known fact that children's growth depends on the quality of their nutrition. However, the mechanisms of fetal and child growth and their interactions with nutrition have not yet been fully elucidated and still pose a challenge to those engaged in the field. Exchanging concepts and knowledge among professionals of various disciplines thus remains very important. This second 'Yearbook' provides an update on the research published between 2013 and 2015. An international team of experts presents papers that shed light on the mechanisms of interaction between nutrition and growth, and provide insight to the readers. Each paper is briefly summarized and supplemented with editorial comments which evaluate the clinical importance of each article and discuss its application.This 'Yearbook' is an important tool for practicing physicians, including pediatricians, subspecialists in pediatric gastroenterology, metabolism and nutrition, and endocrinology. Nutritionists and dieticians, as well as other health professionals involved in the care of children, will also find this to be a useful resource.

Download or read book Hypertension and Cardiovascular Disease written by Emmanuel A. Andreadis and published by Springer. This book was released on 2016-09-20 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive analysis into individualized patient care, and applying evidence‐based medicine while integrating basic medical knowledge with applied medicine. The Editor and the contributors not only discuss important issues on hypertension management and its deleterious consequences if it is not well‐controlled, but also highlight the important signaling pathways involved in the pathogenesis of hypertensive heart disease and cardiac hypertrophy.

Download or read book Textbook of Ion Channels Volume III written by Jie Zheng and published by CRC Press. This book was released on 2023-06-28 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Ion Channels is a set of three volumes that provides a wide-ranging reference source on ion channels for students, instructors and researchers. Ion channels are mem- brane proteins that control the electrical properties of neurons and cardiac cells; medi- ate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical appli- cations. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. Volume III includes coverage of key ion channel regulators and their mechanisms, the role of ion channels working in concert in selected physiological systems, and examples of ion channel mutations and dysfunction in a selection of diseases. Chapters on ion channel regulation include splice variants, calcium–calmodulin regulation, regulation by G pro- teins, and lipids. A selection of ion channels in physiological systems includes ion chan- nels of the heart, ion channels in immune cells and their role in pancreatic beta cells and regulation of insulin secretion, and the role of channels in sperm and eggs. While disease mechanisms are integrated into the chapters of Volume II, Volume III offers special consid- eration of ion channels in epilepsy, cystic fibrosis and pain syndromes. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels, a guide to the technical aspects of ion channel research, offer a modern guide to the properties of major ion channel families, and includecoverage of key examples of regulatory, physiological, and disease roles for ion channels.

Download or read book NO WEDDINGS The Complete Series written by Kat Bastion and published by Kat Bastion and Stone Bastion. This book was released on 2022-01-30 with total page 1253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Available for the first time... NO WEDDINGS: The Complete Series NAMED "BEST OF" BY MULTIPLE ROMANCE BLOGS No Weddings - One Funeral - Two Bar Mitzvahs - Three Christmases - For Valentine's Award-winning author Kat Bastion teams with her husband, Stone Bastion, in the No Weddings Series about Cade Michaelson, a successful man with his sights set on a new venture in business, and Hannah Martin, the woman who makes it personal. NO WEDDINGS: The Complete Series includes the novels: No Weddings One Funeral Two Bar Mitzvahs Three Christmases For Valentine's ...PLUS a sneak peek of HEARTBREAKER, the first spinoff novel in the Unbreakable series Praise for the No Weddings series... "One of the best romantic comedies of the year! Absolute must read!" ~ Agents of Romance "The No Weddings Series is one of the best I have read that follows one couple. Cade and Hannah are both lovable characters, the storyline is real and entertaining, and the banter is fun and witty." ~ Lives & Breathes Book Blog "I loved it, and I mean REALLY loved it!" ~ Orchard Book Club "This is an exceptional series...You find yourself fully engrossed in their world and can't put the book down." ~ Books -n- Kisses "The No Weddings series has a group of such amazing characters; you can't help but relate to them and feel the emotion in every situation they encounter. It has been a long time since a story has made me feel that way let alone an entire series!" ~ Under the Covers Book Blog "The story of Cade & Hannah's relationship is realistic, heart-warming, and filled with real-world connections that shook me in a way that few titles I've read this year have managed...I have loved every minute of the No Weddings series." ~ That's What I'm Talking About ABOUT THE BOOKS... No Weddings Award-winning author Kat Bastion teams with her husband, Stone Bastion, in this first book in the No Weddings Series about Cade Michaelson, a successful man with his sights set on a new venture in business, and Hannah Martin, the woman who makes it personal. One Funeral The stakes climb higher in this second book in the No Weddings Series for Hannah Martin, a woman restrained by her past, and Cade Michaelson, the man who could help set her free. Two Bar Mitzvahs Summer heats up in this third book in the No Weddings Series, where Cade Michaelson strives to balance his and Hannah Martin’s new relationship with the growing demands of his financial success. Three Christmases As the holiday season approaches in this fourth book in the No Weddings Series, Cade Michaelson strives to be better at balancing work and love, and Hannah Martin’s growing ability to trust is put to the test. For Valentine's This steamy nightcap novella, the fifth book in the No Weddings Series, takes us on a post-happily-ever-after adventure as Cade attempts to rewrite Valentine’s Day with his new wife, Hannah. *** PLEASE NOTE *** Scorching (explicit) sex scenes. Fire extinguisher highly recommended. The Best of 2014 No Weddings Series: No Weddings One Funeral Two Bar Mitzvahs Three Christmases For Valentine’s The Unbreakable Series: Standalone novels of beloved characters from The No Weddings series Heartbreaker Rule Breaker Lawbreaker Icebreaker ~ upcoming release Ball Breaker ~ upcoming release

Download or read book The Complete Delta Force Shooters written by M. L. Buchman and published by Buchman Bookworks, Inc.. This book was released on 2020-10-25 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Five romance short story collection with exclusive author intros.) Praise for M. L.’s Delta Force series: * “The contemporary standard bearer of military romance.” * “Top 10 Romance of the Year.” * “(For) a romantic adrenaline junkie.” Discover tales of danger, adventure, and ever-lasting love with the top warriors anywhere. Don’t miss the companion collection: The Complete Delta Force Warriors. (previously published as individual stories)

Download or read book The Complete Tempest Rock Star Series books 1 6 written by Michelle Mankin and published by Michelle Mankin. This book was released on with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Six bestselling full length novels. Your all access backstage pass to the world's most dysfunctional rock band. Tempest rocking. Tempest rolling. Tempest raging out of control. The complete series includes all six books boxed together digitally for the first time ever. Over 1200 pages. It also includes a bonus excerpt of The Right Man. IRRESISTIBLE REFRAIN Two years ago everything changed for the remaining members of the Seattle rock band Tempest. Two years is a long time. Too long to keep on remembering. Not nearly long enough to forget. In trouble with nowhere else to go songstress Lace Lowell seeks refuge with the band during their stop in New York City. It's a risky move for her because they are both there, two impossibly good looking men whose lives are inseparably entwined with hers. One who bruised her heart and one who smashed it into pieces. ENTICING INTERLUDE To the talented vocalist Justin Jones, love is merely a game that he plays by his own rules. But to Bridget Dubois, love and heartache are one and the same. Broken too many times before, the delicate beauty keeps her emotions carefully concealed. Bridget has her own set of rigid rules when it comes to men. She prefers to avoid them altogether, especially dangerously seductive auburn haired emerald eyed players like Justin. CAPTIVATING BRIDGE Warren "War" Jinkins is that guy. The bad one. Tempest's ex front man, an arrogant rock god. The only thing larger than his ego is his capacity for self-destruction. His bad attitude has cost him. His woman. His best friend. His band. Everything. Shaina Bentley is that girl. The good one. Hollywood's pink candy-coated sweetheart. The star of Pinky Swear, television's top rated teen show. He's a one man island. She's a fragile captive soul. Is love a current too dangerous to cross or will it be the bridge that brings them together? RELENTLESS RHYTHM The one she really wants is out of reach. The one he really needs is already taken. Dizzy Lowell, rhythm man for the rising rock band Tempest is a wizard on the guitar and a wonder with women. But the hookup specialist hides his emotional scars beneath his suave exterior. He never lets anyone truly touch him until he meets April Reynolds, the confident bartender of the Diamond Mine. TEMPTING TEMPO Sager Reed the strong and silent bassist for the rock band Tempest is well acquainted with loss. The thoughtful tattoos he designs only hint at his turbulent youth. He buries his guilt about it deeply within his troubled heart. Melinda T. Belle is the daughter of a dysfunctional rock legend. Avoiding emotional entanglement, she has turned her back on nearly everyone and everything she has ever known. Alone, she tries desperately to find fulfillment in the one dream she has left, competitive skiing. Can Sager overcome his dark past? Will Melinda realize her worth? Will they both see that love is only thing that really matters? SCANDALOUS BEAT A rock star. A stripper. Can a hookup lead to a happily ever after? BONUS CONTENT: THE RIGHT MAN A pretty woman and a handsome rock star A modern retelling of Cinderella. Can a hookup for cash lead to a happily ever after? Text ROCK BOOK to 345345 for cover reveal and release alerts from this author. On January 31, 2019 one randomly chosen subscriber will receive an autographed paperback set of the entire Tempest series. (US only)

Download or read book Genetics in Otorhinolaryngology written by Ken Kitamura and published by Karger Medical and Scientific Publishers. This book was released on 2000 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can genetics be useful to general otorhinolaryngologists and their patients? This book summarizes the most recent information on genetic diseases, including deafness and head-and-neck cancer, that is relevant to clinical practice, particularly with reference to accurate genetic counseling. The first part of the volume presents a basic and general review of genetics. Up-to-date information on deafness genes is given and the mouse model for hearing impairment is thoroughly described. The application of molecular analysis of head-and-neck carcinoma has been one of the fundamental breakthroughs in understanding the cell biology of the carcinoma. Two chapters are devoted to the discussion of tumor suppressor genes and oncogenes. This book is highly recommended since genetics, particularly molecular genetics, is still an unfamiliar subject to otorhinolaryngologists.Yet there is a constant need to be alert to the possibility of diagnosing hereditary disorders and to obtain genetic consultation for a complete evaluation. A comprehensive list of references is given for those who wish to find more detailed information.

Download or read book Prognostic and Therapeutic Applications of RKIP in Cancer written by Benjamin Bonavida and published by Academic Press. This book was released on 2020-02-19 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides an update from experts in the field on diagnostics, prognostics and therapeutics Brings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapter Provides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals

Download or read book Molecular Biology in Medicinal Chemistry written by Theodor Dingermann and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. With its examination of these novel methods and generous practical advice, this is essential reading for all pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.

Download or read book Pediatric Nephrology written by Francesco Emma and published by Springer Nature. This book was released on 2022-09-01 with total page 2112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of the previous seven editions, Pediatric Nephrology has become the standard reference text for students, trainees, practicing physicians (pediatricians, nephrologists, internists, and urologists), subspecialists, and allied health professionals seeking information about children’s kidney diseases. It is global in perspective, reflecting the fact that the international group of editors are all acknowledged world experts. The latest edition of this text is no different, providing a comprehensive, state-of-the-art overview on pediatric nephrology. Much like the previous edition, the latest edition reviews the most critical aspects of the field. Topics covered include developmental physiology and diseases, renal physiology and diagnostic approaches, glomerular disease, kidney involvement in systemic diseases, renal tubular disorders, homeostasis, cystic kidney disease and related disorders, urinary tract disorders, hypertension, acute kidney injury, and chronic kidney failure. Unlike the previous edition, however, the chapters in this edition now combine physiology, clinical management, and pathology for ease of use. The latest edition also includes a new section on the evaluation of different disorders that can have multiple etiologies, setting the stage for the evaluation and management of specific diseases. This book serves as a superb resource and an invaluable asset for practitioners, health professionals, and trainees seeking out information about children's kidney diseases.