Download or read book Topics of Clinical Interest in Nonhuman Primates Update Bibliographies written by Cathy A. Johnson-Delaney and published by . This book was released on 1991 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Occupational Health and Safety in the Care and Use of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 2003-06-13 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.
Download or read book The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment written by Joerg Bluemel and published by Academic Press. This book was released on 2015-03-13 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes
Download or read book Mycobacterium in Nonhuman Primates written by Miriam McLean and published by . This book was released on 1994 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Directory of Primatology written by and published by . This book was released on 1992 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Folia Primatologica written by and published by . This book was released on 1992 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethics Dumping written by Doris Schroeder and published by Springer. This book was released on 2017-12-04 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.
Download or read book Laboratory Primate Handbook written by Robert A. Jr. Whitey and published by Academic Press. This book was released on 1973-01-28 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Primate Handbook deals with the proper care and handling, treatment, and transportation of nonhuman primates to be used as research subjects in a laboratory environment. It considers the protection of human and animal health, identification, procurement, and husbandry, as well as compliance with federal regulations. Organized into 10 chapters, this volume begins with an overview of living primates and their classification, followed by procurement and production for biomedical research purposes. It then discusses housing and care of primates; preventive medicine and public health programs aimed at minimizing the hazards that may arise from diseases transmissible between nonhuman primates and man; and restraint and special techniques, including anesthetics and pre-anesthetics. The book also covers nutrition for primates and prevention of nutritional diseases, as well as generalized infectious diseases; parasites that cause disease in primates; and collection of physiological data on primates. Finally, the book looks at federal regulations and policies governing the humane care and treatment of nonhuman primates used in research. This book will benefit biomedical researchers involved in laboratory studies of nonhuman primates.
Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.
Download or read book The Psychological Well Being of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 1998-11-03 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 1985 amendment to the Animal Welfare Act requires those who keep nonhuman primates to develop and follow appropriate plans for promoting the animals' psychological well-being. The amendment, however, provides few specifics. The Psychological Well-Being of Nonhuman Primates recommends practical approaches to meeting those requirements. It focuses on what is known about the psychological needs of primates and makes suggestions for assessing and promoting their well-being. This volume examines the elements of an effective care programâ€"social companionship, opportunities for species-typical activity, housing and sanitation, and daily care routinesâ€"and provides a helpful checklist for designing a plan for promoting psychological well-being. The book provides a wealth of specific and useful information about the psychological attributes and needs of the most widely used and exhibited nonhuman primates. Readable and well-organized, it will be welcomed by animal care and use committees, facilities administrators, enforcement inspectors, animal advocates, researchers, veterinarians, and caretakers.
Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2011-12-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Download or read book Parenting for Primates written by Harriet J Smith and published by Harvard University Press. This book was released on 2009-06-30 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this natural history of primate parenting, Smith compares parenting by nonhuman and human primates. In a narrative rich with vivid anecdotes derived from interviews with primatologists, from her own experience breeding cottontop tamarin monkeys for over thirty years, and from her clinical psychology practice, Smith describes the ways that primates care for their offspring, from infancy through young adulthood.
Download or read book Resource Sharing in Biomedical Research written by Institute of Medicine and published by National Academies Press. This book was released on 1996-12-29 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research.
Download or read book Pocket Handbook of Nonhuman Primate Clinical Medicine written by Angela Courtney and published by CRC Press. This book was released on 2012-10-18 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sources of clinical treatment information on nonhuman primates are generally scattered across journals, textbooks, conferences, personal conversations, and more. However, when a clinician on the treatment floor is faced with a patient requiring an immediate treatment decision, time spent on making an informed decision becomes a critical factor. An alternative to conducting a literature search in time-sensitive situations, the Pocket Handbook of Nonhuman Primate Clinical Medicine supplies guidance and initial direction on diagnosis and treatment, including working doses based on past case experience. It is the frank, to-the-point nature of the writing that makes readers feel as if they had just asked a colleague how to approach a clinical problem and obtained a quick, "what you need to know" answer. The chapter authors draw on personal experience to describe commonly encountered clinical conditions and how to treat these cases—including not only the "dos" but also the "don’ts." This format gives readers easy access to clinical signs, diagnostic criteria, and options for treatment. The Pocket Handbook of Nonhuman Primate Clinical Medicine is a convenient, concise, case-based handbook written by and for clinicians in charge of the diagnosis and treatment of nonhuman primate patients. Available in both print and electronic formats, this handbook saves readers from having to wade through pages of data and case studies to find answers when time is a factor on the clinic floor.
Download or read book Agricultural Libraries Information Notes written by and published by . This book was released on 1987 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Xenotransplantation written by David K. C. Cooper and published by Springer Nature. This book was released on 2020-09-08 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides an illuminating examination of the current state of xenotransplantation – grafting or transplanting organs or tissues between members of different species – and how it might move forward into the clinic. To be sure, this is a critical topic, as a major problem that remains worldwide is an inadequate supply of organs from deceased human donors, severely limiting the number of organ transplants that can be performed each year. Based on presentations given at a major conference on xenotransplantation, this title includes important views from many leading experts who were invited to present their data and opinions on how xenotransplantation can advance into the clinic. Attention was concentrated on pig kidney and heart transplantation as it is in regard to these organs that most progress has been made. Collectively, these chapters effectively highlight the many advantages of xenotransplantation to patients with end-stage organ failure, thereby encouraging the mapping of a concrete pathway to clinical xenotransplantation. The book is organized across 22 chapters, beginning with background information on clinical and experimental xenotransplantation. Following this are discussions addressing how pigs can be genetically engineered for their organs to be resistant to the human immune response through deletion of pig xenoantigens, and the insertion of ‘protective’ human transgenes. Subsequent chapters analyze complications that arise in practice, comparing allotransplant and xenotransplant rejection. The selection of the ideal patients for the first clinical trials is discussed. Finally, the book concludes with an analysis on the regulatory, economic, and social aspects of this research, including FDA perspectives and the sensitive, psychosocial factors regarding allotransplantation and xenotransplantation. A major and timely addition to the literature, Clinical Xenotransplantation will be of great interest to all researchers, physicians, and academics from other disciplines with an interest in xenotransplantation.
Download or read book Apes and Human Evolution written by Russell H. Tuttle and published by Harvard University Press. This book was released on 2014-02-17 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterwork, Russell H. Tuttle synthesizes a vast research literature in primate evolution and behavior to explain how apes and humans evolved in relation to one another, and why humans became a bipedal, tool-making, culture-inventing species distinct from other hominoids. Along the way, he refutes the influential theory that men are essentially killer apes—sophisticated but instinctively aggressive and destructive beings. Situating humans in a broad context, Tuttle musters convincing evidence from morphology and recent fossil discoveries to reveal what early primates ate, where they slept, how they learned to walk upright, how brain and hand anatomy evolved simultaneously, and what else happened evolutionarily to cause humans to diverge from their closest relatives. Despite our genomic similarities with bonobos, chimpanzees, and gorillas, humans are unique among primates in occupying a symbolic niche of values and beliefs based on symbolically mediated cognitive processes. Although apes exhibit behaviors that strongly suggest they can think, salient elements of human culture—speech, mating proscriptions, kinship structures, and moral codes—are symbolic systems that are not manifest in ape niches. This encyclopedic volume is both a milestone in primatological research and a critique of what is known and yet to be discovered about human and ape potential.
