Download or read book The Virus and the Vaccine written by Debbie Bookchin and published by Macmillan + ORM. This book was released on 2013-07-02 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before... Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans. But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.
Download or read book Framework for Equitable Allocation of COVID 19 Vaccine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-11-30 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time frame. Vaccination against this novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), offers the possibility of significantly reducing severe morbidity and mortality and transmission when deployed alongside other public health strategies and improved therapies. Health equity is intertwined with the impact of COVID-19 and there are certain populations that are at increased risk of severe illness or death from COVID-19. In the United States and worldwide, the pandemic is having a disproportionate impact on people who are already disadvantaged by virtue of their race and ethnicity, age, health status, residence, occupation, socioeconomic condition, or other contributing factors. Framework for Equitable Allocation of COVID-19 Vaccine offers an overarching framework for vaccine allocation to assist policy makers in the domestic and global health communities. Built on widely accepted foundational principles and recognizing the distinctive characteristics of COVID-19, this report's recommendations address the commitments needed to implement equitable allocation policies for COVID-19 vaccine.
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Download or read book CDC Yellow Book 2018 Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Download or read book The Vaccine written by Joe Miller and published by St. Martin's Press. This book was released on 2022-02-01 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winners of the Paul Ehrlich Prize The dramatic story of the married scientists who founded BioNTech and developed the first vaccine against COVID-19. Nobody thought it was possible. In mid-January 2020, Ugur Sahin told Özlem Türeci, his wife and decades-long research partner, that a vaccine against what would soon be known as COVID-19 could be developed and safely injected into the arms of millions before the end of the year. His confidence was built upon almost thirty years of research. While working to revolutionize the way that cancerous tumors are treated, the couple had explored a volatile and overlooked molecule called messenger RNA; they believed it could be harnessed to redirect the immune system's forces against any number of diseases. As the founders of BioNTech, they faced widespread skepticism from the scientific community at first; but by the time Sars-Cov-2 was discovered in Wuhan, China, BioNTech was prepared to deploy cutting edge technology and create the world’s first clinically approved inoculation for the coronavirus. The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age; it will reveal how Doctors Sahin and Türeci were able to develop twenty vaccine candidates within weeks, convince Big Pharma to support their ambitious project, navigate political interference from the Trump administration and the European Union, and provide more than three billion doses of the Pfizer/BioNTech vaccine to countries around the world in record time. Written by Joe Miller—the Financial Times’ Frankfurt correspondent who covered BioNTech’s COVID-19 project in real time—with contributions from Sahin and Türeci, as well as interviews with more than sixty scientists, politicians, public health officials, and BioNTech staff, the book covers key events throughout the extraordinary year, as well as exploring the scientific, economic, and personal background of each medical innovation. Crafted to be both completely accessible to the average reader and filled with details that will fascinate seasoned microbiologists, The Vaccine explains the science behind the breakthrough, at a time when public confidence in vaccine safety and efficacy is crucial to bringing an end to this pandemic.
Download or read book A Shot to Save the World written by Gregory Zuckerman and published by Penguin. This book was released on 2021-10-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An inspiring and informative page-turner." –Walter Isaacson Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.
Download or read book Revelation written by and published by Canongate Books. This book was released on 1999-01-01 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: The final book of the Bible, Revelation prophesies the ultimate judgement of mankind in a series of allegorical visions, grisly images and numerological predictions. According to these, empires will fall, the "Beast" will be destroyed and Christ will rule a new Jerusalem. With an introduction by Will Self.
Download or read book Epidemiology and Prevention of Vaccine preventable Diseases written by and published by . This book was released on 2000 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Identification of Biomarkers New Treatments and Vaccines for COVID 19 written by Paul C. Guest and published by Springer Nature. This book was released on 2021-07-19 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as diabetes and obesity. As the cases and death rate remain high, there are justified fears of this virus remaining for several months or years to come. To address this, a rapid and unprecedented worldwide mobilization effort has begun to identify effective treatments and develop vaccines. As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers’ understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss new treatment approaches, vaccine development, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.
Download or read book Vaccine Analysis Strategies Principles and Control written by Brian K. Nunnally and published by Springer. This book was released on 2014-11-27 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
Download or read book Adverse Events Associated with Childhood Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 1993-01-01 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.
Download or read book The Panic Virus written by Seth Mnookin and published by Simon and Schuster. This book was released on 2012-01-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.
Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Download or read book The Covid 19 Vaccine Guide written by Kathryn M. Edwards and published by Simon and Schuster. This book was released on 2021-03-23 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: What you should know about the Covid-19 vaccines from top experts in the field. As the SARS-Cov2 virus emerged and spread globally in early 2020, unprecedented international efforts began to develop and test vaccines to control the devastating pandemic. This book focuses on the remarkable progress in developing vaccines, the amazing effectiveness of the early vaccines, and the challenges of delivering them to the population. To put this extraordinary progress into perspective, the history of other vaccines is presented and their roles in individual protection and protection of the community, “vaccines that protect the unvaccinated,” are outlined. The rigorous processes whereby vaccines are evaluated in distinct phases and the steps that must be met prior to obtaining regulatory approval for both vaccine safety and effectiveness are highlighted. Multiple vaccine approaches are reviewed, including new approaches such as “messenger or mRNA vaccine” that may revolutionize future vaccine development. The comprehensive models used to provide recommendations and priorities for vaccination of groups of people at risk are summarized. The book also focuses on the questions that remain unanswered after the vaccines are approved. These include duration of immunity, risk factors for vaccine failure, impact of viral evolution and variant strains, and assessment of both immediate and long-term safety. The authors also address concerns about vaccine acceptance including roll-out, access, and detailed and trusted sources of information.
Download or read book Epidemiology and Prevention of Vaccine Preventable Diseases 13th Edition E Book written by Jennifer Hamborsky, MPH, MCHES and published by Public Health Foundation. This book was released on 2015-10-19 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Public Health Foundation (PHF) in partnership with the Centers for Disease Control and Prevention (CDC) is pleased to announce the availability of Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition or “The Pink Book” E-Book. This resource provides the most current, comprehensive, and credible information on vaccine-preventable diseases, and contains updated content on immunization and vaccine information for public health practitioners, healthcare providers, health educators, pharmacists, nurses, and others involved in administering vaccines. “The Pink Book E-Book” allows you, your staff, and others to have quick access to features such as keyword search and chapter links. Online schedules and sources can also be accessed directly through e-readers with internet access. Current, credible, and comprehensive, “The Pink Book E-Book” contains information on each vaccine-preventable disease and delivers immunization providers with the latest information on: Principles of vaccination General recommendations on immunization Vaccine safety Child/adult immunization schedules International vaccines/Foreign language terms Vaccination data and statistics The E-Book format contains all of the information and updates that are in the print version, including: · New vaccine administration chapter · New recommendations regarding selection of storage units and temperature monitoring tools · New recommendations for vaccine transport · Updated information on available influenza vaccine products · Use of Tdap in pregnancy · Use of Tdap in persons 65 years of age or older · Use of PCV13 and PPSV23 in adults with immunocompromising conditions · New licensure information for varicella-zoster immune globulin Contact [email protected] for more information. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page
Download or read book Viruses Pandemics and Immunity written by Arup K. Chakraborty and published by MIT Press. This book was released on 2021-02-16 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: How viruses emerge to cause pandemics, how our immune system combats them, and how diagnostic tests, vaccines, and antiviral therapies work. Throughout history, humans have contended with pandemics. History is replete with references to plagues, pestilence, and contagion, but the devastation wrought by pandemics had been largely forgotten by the twenty-first century. Now, the enormous human and economic toll of the rapidly spreading COVID-19 disease offers a vivid reminder that infectious disease pandemics are one of the greatest existential threats to humanity. This book provides an accessible explanation of how viruses emerge to cause pandemics, how our immune system combats them, and how diagnostic tests, vaccines, and antiviral therapies work-- concepts that are a foundation for our public health policies.
Download or read book Longshot written by David Heath and published by . This book was released on 2023-01-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the incredible story of the scientists who created a coronavirus vaccine in record time. In Longshot, investigative journalist David Heath takes readers inside the small group of scientists whose groundbreaking work was once largely dismissed but whose feat will now eclipse the importance of Jonas Salk's polio vaccine in medical history. With never-before-reported details, Heath reveals how these scientists overcame countless obstacles to give the world an unprecedented head start when we needed a COVID-19 vaccine. The story really begins in the 1990s, with a series of discoveries that were timed perfectly to prepare us for the worst pandemic since 1918. Readers will meet Katalin Karikó, who made it possible to use messenger RNA in vaccines but struggled for years just to hang on to her job. There's also Derrick Rossi, who leveraged Karikó's work to found Moderna but was eventually expelled from his company. And then there's Barney Graham at the National Institutes of Health, who had a career-long obsession with solving the riddle of why two toddlers died in a vaccine trial in 1966, a tragedy that ultimately led to a critical breakthrough in vaccine science. With both foresight and luck, Graham and these other crucial scientists set the course for a coronavirus vaccine years before COVID-19 emerged in Wuhan, China. The author draws on hundreds of hours of interviews with key players to tell the definitive story about how the race to create the vaccine sparked a revolution in medical science.
