Download or read book Saving Lives Buying Time written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Download or read book Silent Spring written by Rachel Carson and published by Houghton Mifflin Harcourt. This book was released on 2002 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential, cornerstone book of modern environmentalism is now offered in a handsome 40th anniversary edition which features a new Introduction by activist Terry Tempest Williams and a new Afterword by Carson biographer Linda Lear.

Download or read book DDT written by United States. Environmental Protection Agency and published by . This book was released on 1975 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Late Lessons from Early Warnings written by European Environment Agency and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DDT and the American Century written by David Kinkela and published by Univ of North Carolina Press. This book was released on 2011-11-07 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praised for its ability to kill insects effectively and cheaply and reviled as an ecological hazard, DDT continues to engender passion across the political spectrum as one of the world's most controversial chemical pesticides. In DDT and the American Century, David Kinkela chronicles the use of DDT around the world from 1941 to the present with a particular focus on the United States, which has played a critical role in encouraging the global use of the pesticide. Kinkela's study offers a unique approach to understanding both this contentious chemical and modern environmentalism in an international context.

Download or read book Malaria Control During Mass Population Movements and Natural Disasters written by Program on Forced Migration and Health at the Mailman School of Public Health of Columbia University and published by National Academies Press. This book was released on 2003-01-16 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of Columbia University have commissioned a series of epidemiological reviews on priority public health problems for forced migrants that will update the state of knowledge. Malaria Control During Mass Population Movements and Natural Disasters- the first in the series, provides a basic overview of the state of knowledge of epidemiology of malaria and public health interventions and practices for controlling the disease in situations involving forced migration and conflict.

Download or read book Insecticides Resistance written by Stanislav Trdan and published by BoD – Books on Demand. This book was released on 2016-03-02 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 20 chapters, which are divided into 5 sections. Section 1 covers different aspects of insecticide resistance of selected economically important plant insect pests, whereas section 2 includes chapters about the importance, development and insecticide resistance management in controlling malaria vectors. Section 3 is dedicated to some general questions in insecticide resistance, while the main topic of section 4 is biochemical approaches of insecticide resistance mechanisms. Section 5 covers ecologically acceptable approaches for overcoming insecticide resistance, such are the use of mycoinsecticides, and understanding the role of some plant chemical compounds, which are important in interactions between plants, their pests and biological control agents.

Download or read book DDT Silent Spring and the Rise of Environmentalism written by Thomas R. Dunlap and published by University of Washington Press. This book was released on 2008 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: No single event played a greater role in the birth of modern environmentalism than the publication of Rachel Carson'sSilent Springand its assault on insecticides. The documents collected by Thomas Dunlap trace shifting attitudes toward DDT and pesticides in general through a variety of sources: excerpts from scientific studies and government reports, advertisements from industry journals, articles from popular magazines, and the famous "Fable for Tomorrow" fromSilent Spring. Beginning with attitudes toward nature at the turn of the twentieth century, the book moves through the use and early regulation of pesticides; the introduction and early success of DDT; the discovery of its environmental effects; and the uproar overSilent Spring. It ends with recent debates about DDT as a potential solution to malaria in Africa. "A superb collection. Included here are the texts that galvanized Rachel Carson to writeSilent Springand inspired her to insist on a new vision of cooperation between man and nature. Dunlap's book provides the context for one of the defining debates of our time and shows us why a resolution remains so elusive." - Linda Lear, biographer and author ofRachel Carson: Witness for Nature "To understand how DDT could win its developer a Nobel Prize and then be banned just decades later, read this book. Read it, too, if you want to understand the modern environmental movement. In these pages, those who helped make history tell you, in their own words, what happened." - Edmund P. Russell, University of Virginia "This thought-provoking and occasionally surprising collection of readings brings needed attention to Rachel Carson and her work. Dunlap's book will prove valuable for classes in environmental studies and American environmental history and for historians studying conflicts over pesticides." - Nancy Langston, Professor, University of Wisconsin-Madison "A fascinating and thought-provoking collection of texts that will give readers whole new perspectives on this critical controversy in the history of environmental thought." - William Cronon, University of Wisconsin-Madison "Students can use this collection to gain greater understanding of the development of the environmental movement, changing ideas about progress, science, and technology, as well as changing ideas about the role of nature in the modern world." - David Stradling, University of Cincinnati Thomas R. Dunlapis professor of history at Texas A & M University. He is the author of four books includingFaith in Nature: Environmentalism as Religious QuestandDDT: Scientists, Citizens, and Public Policy.

Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book To Spray Or Not to Spray written by and published by . This book was released on 1995 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Mosquito Wars written by Gordon M. Patterson and published by . This book was released on 2004 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Mosquito Wars is a fascinating chronicle of the history of mosquito control in Florida over the past century. It details the positive contributions made by the profession's many managers and scientists. This work thoroughly describes how this profession has helped make Florida habitable and also puts the environmental controversies of mosquito control in the proper perspective."--Douglas Carlson, Indian River Mosquito Control District "The Mosquito Wars is an entertaining, accurate description of how mosquito control has developed in Florida to its current state."--Dennis Moore, editor-in-chief, Wing Beats The Mosquito Wars presents a comprehensive and insightful analysis of the development of human efforts to wage war on mosquitoes in 20th-century Florida. Drawing on archival records, interviews, and published records, Gordon Patterson provides readers with a context for understanding how mosquito control has shaped the environment of contemporary Florida. Patterson reveals how the discovery that yellow fever, malaria, and dengue fever were mosquito-borne diseases had a profound impact on Florida's development in the first half of the 20th century. State agencies organized campaigns from Pensacola to Key West against the disease-bearing insects. World War II opened a new era in mosquito control; the United States Department of Agriculture pioneered the use of DDT as an insecticide, and by 1944 army and navy pilots were regularly flying anti-mosquito missions. The 1950s ushered in a new objective--to reduce not only disease-bearing mosquitoes but also pest and nuisance mosquitoes. The growing problem of chemical resistance, however, led to the use of new and more powerful pesticides, raising concerns about the environmental impact of these chemicals on biologically sensitive wetlands. The ensuing controversy resulted in the rewriting of mosquito control laws in 1986. The continuing occurrences of encephalitis and the recent arrival of the West Nile virus, both transmitted by mosquitoes, dictate that mosquito control will continue to play a vital role in protecting the public's health and welfare. The Mosquito Wars presents a balanced, entertaining, and informative examination of this often heroic and sometimes tragic history of the battle to control mosquitoes in Florida. Gordon Patterson is professor of history at the Florida Institute of Technology, Melbourne.

Download or read book The Fever written by Sonia Shah and published by Macmillan + ORM. This book was released on 2010-06-29 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This deep dive into humanity’s very long fight against malaria is “a vivid and compelling history with a message that’s entirely relevant today” (Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction). In a time when every emergent disease inspires waves of panic, why aren’t we doing more to eradicate one of our oldest foes? And how does a parasitic disease that we’ve known how to prevent for more than a century still infect 500 million people every year, killing nearly 1 million of them? Philanthropists from Laura Bush to Bono to Bill Gates have contributed to the effort to find a cure for malaria—but there’s much more that can be done to minimize its deadly effects. In The Fever, journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we’ve invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria’s jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity. “Fascinating . . . an absorbing account of human ingenuity and progress, and of their heartbreaking limitations.” —Publishers Weekly “A thrilling detective story, spanning centuries, about our erratic pursuit of a villain still at large . . . rich in colorful detail.” —Malcolm Molyneux, Professor, Liverpool School of Tropical Medicine

Download or read book Pest Resistance to Pesticides written by G. P. Georghiou and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of resistance to pesticides is generally acknowledged as one of the most serious obstacles to effective pest control today. Since house flies first developed resistance to DDT in 1946, more than 428 species of arthropods, at least 91 species of plant pathogens, five species of noxious weeds and two species of nematodes were reported to have developed strains resistant to on~ or more pesticides. A seminar of U. S. and Japanese scientists was held in Palm Springs, California, during December 3-7, 1979, under the U. S. -Japan Cooperative Science Program, in order to evaluate the status of research on resistance and to discuss directions for future emphasis. A total of 32 papers were presented under three principal topics: Origins and Dynamics of Resistance (6), Mechanisms of Resistance (18), and Suppression and Management of Resistance (8). The seminar was unique in that it brought together for the first time researchers from the disciplines of entomology, plant pathology and weed science for a comprehensive discussion of this common problem. Significant advances have been identified in (a) the development of methods for detection and monitoring of resistance in arthropods (electrophoresis, diagnostic dosage tests) and plant pathogens, (b) research on biochemical and physiological mechanisms of resis tance (cytochrome p450, sensitivity of target site, gene regulation), (c) the identification and quantification of biotic, genetic and operational factors influencing the evolution of resistance, and (d) the exploration of pest management approaches incorporating resis tance-delaying measures.

Download or read book Handbook for Integrated Vector Management written by World Health Organization and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated vector management (IVM) is a rational decision-making process for optimal use of resources for vector control. The aim of the IVM approach is to contribute to achievement of the global targets set for vector-borne disease control, by making vector control more efficient, cost-effective, ecologically sound and sustainable. Use of IVM helps vector control programs to find and use more local evidence, to integrate interventions where appropriate and to collaborate within the health sector and with other sectors, as well as with households and communities. By reorientating to IVM, vector control programs will be better able to meet the growing challenges in the control of malaria, dengue and other vector-borne diseases in the face of dwindling public sector human and financial resources. This handbook presents an operational framework to guide managers and those implementing vector-borne disease control programs in designing more efficient, cost-effective systems. As a national IVM policy and an intersectoral steering committee are essential for establishing IVM as a national strategy, the handbook begins with the policy and institutional framework for IVM. Policy analysis is a means for identifying options for policy reform and suggesting instruments for implementing policy. IVM transforms the conventional system of vector control by making it more evidence-based, integrated and participative. This may require changes in roles, responsibilities and organizational links. The transition to IVM involves both reorientation of vector-borne disease control programs and embedding IVM within local health systems. Intersectoral partnerships and collaboration at both national and local levels will result in cost savings and benefits to other health services. Other relevant sectors, such as agriculture, environment, mining, industry, public works, local government and housing, should incorporate IVM and vector control into their own activities to prevent vector proliferation and disease transmission. Planning and implementing IVM involve assessing the epidemiological and vector situation at country level, analyzing the local determinants of disease, identifying and selecting vector control methods, assessing requirements and resources and designing locally appropriate implementation strategies. Solid evidence on the cost-effectiveness of interventions and their underlying parameters and a comprehensive vector surveillance system are essential for locally appropriate decision-making. Capacity-building, in particular human resource development, is a major challenge, because the IVM strategy requires skilled staff and adequate infrastructure at central and local levels. The handbook outlines the core functions and essential competence required for IVM at central and local levels, complementing a separate set of documents containing the Core structure for training curricula on integrated vector management and associated training materials. Like any new approach, IVM must be actively advocated and communicated in order to become established. The handbook lays out the elements and processes of IVM to enable policy-makers, donors and implementing partners to use it for vector-borne disease control. During the period of transition and consolidation of an IVM strategy, regular feedback is required on performance and impact in order to ensure continued support. The general public must also be made aware of the strategy and participate in its implementation. The communication tools for reaching the public are the media and various types of educational interventions to increase their knowledge and skills, which should lead to behavioral change and empowerment. The final section presents a comprehensive framework for monitoring and evaluation of IVM, covering aspects discussed in the previous sections. Indicators and methods for measuring process, outcomes and impact are proposed.

Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Download or read book Manual on Environmental Management for Mosquito Control written by World Health Organization and published by . This book was released on 1982 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: