Download or read book The Transformed Cell written by Ivan Cameron and published by Elsevier. This book was released on 1981-01-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Transformed Cell deals with many of the differences that may exist between transformed cells and their normal counterparts. Topics covered range from malignancy and the cell surface to cell cycle regulation in normal and transformed cells; phenotypic expression of malignant transformation and its relationship to energy metabolism; and virus-induced transformation. The involvement of cyclic nucleotides in transformation is also discussed, together with intracellular pH and growth control in eukaryotic cells. This book is comprised of 12 chapters and begins with a brief description of terminology and basic concepts relating to cancer cells, as well as some comments on tumorigenicity and cell transformation. The next two chapters explore the evidence for and against the possible correlation of in vivo tumorigenicity to in vitro changes in the cytoskeletal system; anchorage-dependent growth; plasminogen activator production; agglutinability by lectins; and cell surface and plasma membrane properties. The regulation of cell proliferation and the relationships between ion movement and energy metabolism in normal and transformed cells are then examined, along with the transformation of normal cells by infection with new genetic material from tumor viruses. The remaining chapters focus on selected cellular properties that have been purported to differ between the normal and transformed cell, with particular reference to cyclic nucleotides; polyamine metabolism; cell viscosity; mobility of cellular water; intracellular pH; and element concentration. This monograph will be of interest to biologists and medical practitioners devoted to understanding cancer cell biology and cancer therapy.
Download or read book The True Story of a Mouse Who Never Asked for It written by Ana Cristina Herreros and published by Unruly Records. This book was released on 2021-06-22 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The True Story of a Mouse Who Never Asked for It is a visually striking, deeply feminist, contemporary retelling of a Spanish folk tale, rediscovered and brought to new life by author Ana Cristina Herreros and illustrator Violeta Lopiz. In Herreros and Lopiz's version--which sharply diverges from the most mainstream and popularized telling of the story--a mouse is approached by many suitors, rejecting all but one: a cat, whose gentle meow assures her that he won't bring her harm. But one must remember that a kitten always grows up to be a cat...and thusly, will devour the mouse.
Download or read book Development and Recognition of the Transformed Cell written by M.I. Greene and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the phenotypic and genetic features that characterize the malignant cell is a rapidly growing and changing field. Clearly new insights into the processes involved in normal and abnormal cell growth will facilitate our understanding of events relevant to cancer and cellular differentiation. Early studies on genetic fea tures associated with cancer focused on chromosomal abnormalities that were observable in several human malignancies. The more recent examination of onco genes and the proteins they encode has helped pinpoint many steps in different processes that might be involved in cancer. Immunologic studies of cancer have also developed from an imprecise series of investigations to a more detailed molecular examination of cell-surface struc tures that can be recognized immunologically. In the course of the development of modern tumor immunology, it has become clear that many of the antigens that can be recognized appear to be the products of genes involved in cell growth. Fur thermore, changes in the cell surface of malignant cells have often been found to include alteration of nonprotein constituents.
Download or read book Interferons written by Thomas Merigan and published by Elsevier. This book was released on 2012-12-02 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interferons documents the proceedings of a major international conference on Chemistry and Biology of Interferons: Relationship to Therapeutics held at Squaw Valley, California, in March 1982. The meeting was one of the 1982 UCLA Symposia on Molecular and Cellular Biology organized through the Molecular Biology Institute of the University of California at Los Angeles. The book is organized into four parts. Part I presents papers on recombinant DNA production of interferon. It includes studies on the synthesis of human immune interferon in E. coli and monkey cells; the expression of human ß interferon gene in heterologous cells; and the molecular activities of recombinant and hybrid leukocyte interferons. Part II deals with the biology of interferons, covering topics such as interferon production control process; the effect of interferon on cellular enzymes; and human amniotic interferon. Part III examines the factors relevant to clinical application of interferons, including structure-function studies with human interferon-gamma and on human alpha interferon. Part IV presents clinical studies of interferon, such as interferon a trials in human tumor diseases and interferon in renal transplant recipients.
Download or read book The Progressive Road to Silent Reading written by William Louis Ettinger and published by . This book was released on 1922 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tissue Type Plasminogen Activity written by Cornelius Kluft and published by CRC Press. This book was released on 2018-01-18 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is made possible by the enthusiastic contributions of the authors of the chapters. They have been invited from young and active scientists in the field of t-PA research. I am grateful for their contribution and for the fact that all accepted the specifications of their chapter in order to obtain a structured book. Inevitably, some overlap does exist; on the one hand to enable controversial or unsettled areas to be discussed by the different experts with a different approach and background.It is a particular pleasure and honor that Dr. T. Astrup, as an eye-witness and essential contributor to the history of t-PA discovery and research, gives a unique account of the history of t-PA research in the first chapter of the book.
Download or read book Research Awards Index written by and published by . This book was released on 1978 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Cancer Research written by and published by Academic Press. This book was released on 1983-09-27 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research
Download or read book Carcinogenesis Abstracts written by and published by . This book was released on 1980 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Leukemia written by I.L. Weissman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: and how the known vertebrate homologues of these genes are expressed normally in differentiation and proliferation pathways as well as abnormal ly in well-defined lymphomagenic and other oncogenic pathways. What emerged from this meeting are a better understanding of the evolution of these gene systems themselves and an elucidation of simpler systems open to more rapid genetic and molecular genetic analysis to reveal the normal functions of these genes and their gene products. Thus we sought new answers to several old questions concerning differenti ation, proliferation, and neoplastic transformation. We gathered together in an unusual format - that of the unique Dahlem Workshops - not just to reiterate data which has recently emerged but to think about how these findings might lead to new approaches for the understanding and therapy of the leukemias and lymphomas. We deliberately chose experts from several different disciplines, ranging from the clinicians who diag nose, describe, and treat these maladies, to the molecular geneticists trying to reduce the analysis of the problem to its simplest variables in the simplest systems possible.
Download or read book Cell Transformation written by J. Celis and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Mouse with the Question Mark Tail written by Richard Peck and published by Penguin. This book was released on 2013-07-02 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Set off on an amazing quest with this lovable orphaned mouse. The tiniest mouse in the Royal Mews is such a mystery he doesn’t even know his own name! He scampers off on a epic adventure in and around Buckingham Palace with a plan to seek the advice of Queen Victoria. The exhilarating journey takes him to strange and wonderful places, but will it help him discover who he is and where he came from? This delightful follow-up to the acclaimed Secrets at Sea from Newbery Medal winner Richard Peck is full of laughs, surprises and excitement. “This clever yarn should delight fans of animal adventure stories.” —Booklist, starred review “Readers will gleefully suspend disbelief as they trace Mouse Minor’s exciting journey.” —Publishers Weekly, starred review
Download or read book Modulation of MHC Antigen Expression and Disease written by G. Eric Blair and published by Cambridge University Press. This book was released on 1995-11-09 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumor and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression--explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression--both in the etiology of certain diseases and in possible immunotherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumor rejection. This book will be valuable to researchers and clinicians in molecular biology, immunology, oncology, and virology.
Download or read book Library of the World s Best Literature Ancient and Modern written by Charles Dudley Warner and published by . This book was released on 1896 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Columbia University Course in Literature written by and published by . This book was released on 1928 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Warner Library written by Charles Dudley Warner and published by . This book was released on 1917 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt:
