Download or read book The Preparation of 1 sulfur Substituted 1 3 dienes and Their Utilization in 4 2 Cycloaddition Reactions written by Zenyk Bohdan Kosarych and published by . This book was released on 1981 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 1 4 Cycloaddition Reaction The Diels Alder Reaction in Heterocyclic Syntheses written by Jan Hamer and published by Elsevier. This book was released on 2013-07-19 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 8: 1,4-Cycloaddition Reactions: The Diels-Alder Reaction in Heterocyclic Syntheses describes 1,4-cycloaddition reactions leading to the formation of five- or six-membered heterocyclic compounds. Divided into 13 chapters, this book starts with an overview of various 1,4-cycloaddition reaction equations in the presence of at least one atom other than carbon. The following chapters describe the reaction mechanisms of five- or six-membered ring formed upon reaction with a dienophile, which contains an atom other than carbon. Considerable chapters are devoted to compounds used as dienophiles, including trivalent phosphorus, cyanogens and cyanogens-like compounds, imino, azo, carbonyl, thiocarbonyl, and diene compounds, as well as oxygen. Other chapters highlight some 1,4-cycloaddition reactions taking place through free radical intermediates. This book is of value to organic and research chemists, as well as undergraduate and graduate organic chemistry students.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2004 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transition Metal Mediated Stereoselective Higher order 6 4 and Diels Alder 4 2 Cycloaddition Reactions written by Ramakrishna Reddy Pidaparthi and published by . This book was released on 2011 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have prepared various substituted cobaloxime dienes and studied extensively their reactivities in Diels-Alder reactions. Based on the studies with cobaloxime chemistry, we concluded that increased exo selectivities were possible with the insertion of the transition metals in the 2-position of the diene moiety. In the first part of this study, we will describe the higher-order [6+4] and Diels-Alder [4+2] reactions of the cobaloxime dienes with various tropones. The reaction pathway [6+4 vs 4+2] largely depends on the substituents on the tropone moiety where as the stero and regioselectivity is determined only by the cobaloxime. In order to overcome the problems persisting with those dienes in catalytic reactions, we have now moved on to main group element substituted dienyl compounds which are benign to nature, easy to handle and mild in reactivities. These main group element substituted dienes can be transmetalated efficiently to catalytic quantities of transition metals in order to get all the enhanced selectivities mentioned above. We have already established the pathway by using boron substituted dienes. Herein, we describe various methods used in the synthesis of stable silyl dienes from inexpensive starting materials and show their improved regio and stereoselective reactions in Diels-Alder, cross-coupling, and domino reactions.
Download or read book Basic Principles of Organic Chemistry written by John D. Roberts and published by . This book was released on 1977 with total page 1596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes.
Download or read book Synthesis of 2 boron Substituted 1 3 dienes and Their Diels Alder Suzuki Cross Coupling Reactions written by Liqiong Wang and published by . This book was released on 2012 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clerodane diterpenoids represent a large group of secondary metabolites which are distributed widely in nature. Over a thousand members have been isolated to date, many of which possess interesting biological activities: antifeedant, antitumor, antifungal, antibiotic, anti-peptic ulcer and so on. Although synthetic approaches to the transclerodanes abound, cis-clerodane syntheses are rare. The long term objective of this research is to make highly reactive dienes which would undergo Diels-Alder (D-A) reactions with sterically crowded dienophiles to construct cis-clerodane compounds. In previous work, 2-boron-1,3-dienes had shown a high propensity toward self D-A dimerization. Different strategies were tried to prepare dienes without dimerization and seven boron substituted dienes were prepared in good yields. The tri-coordinated boron dienes are less stable than the tetra-coordinated dienes because the boron atom is stabilized by donating electron pairs or groups in the latter type. The reactivity of these boron substituted dienes (2-diethanolaminoborate-1,3-butadiene) in D-A and Suzuki cross coupling reactions were tested and evaluated. Testing concluded that in D-A reactions high yields (> 90%) were found in the reactions of boron substituted 1,3-dienes and N-phenyl maleimide at room temperature or lower. The fastest diene (2-diethanolaminoborate-1,3-butadiene) reacted with a t[subscript 1/2] less than 4 minutes at -10 °C. The 2-diethanolaminoborate-1,3-butadiene has a high HOMO energy compared to its BF3 diene counterpart which accelerates its D-A reactions. High regioselectivities (16:1) were found in the D-A reactions of unsymmetrical dienophiles and 2-diethanolaminoborate-1,3-butadiene. Both high yields and regioselectivities were achieved in Suzuki cross coupling reactions of the resulting boron substituted D-A cycloadducts. Using this methodology, 2-diethanolaminoborate-1,3-butadiene is a promising precursor in providing a potential tool to asymmetric synthesis. Three boron substituted dienes reacted with n-phenylmaleimide very quickly, from seconds to 2 hours. All three dienes are stable at 0°C for more than 2 years. The research also revealed that 4 dienes can be used in tandem D-A/Suzuki cross coupling reactions. High yields and good selectivities were obtained. The possible mechanism of tandem reactions showed that Pd(II) acts as a Lewis acid catalyst to catalyze the D-A reaction between boron substituted dienes and dienophiles followed by Suzuki cross coupling reactions. A possible unstable novel intermediate, a palladium substituted diene, was observed in the reaction by NMR.
Download or read book Directory of Graduate Research written by American Chemical Society. Committee on Professional Training and published by . This book was released on 2005 with total page 1932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Download or read book Modern Phosphonate Chemistry written by Philippe Savignac and published by CRC Press. This book was released on 2003-04-28 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: A century after their discovery, phosphonates have become important compounds recognized both for their use as efficient reagents in organic synthesis and for their biological and industrial importance. This unique, up-to-date reference presents a concise summary of the state of the art in phosphonate chemistry, covering the role of phosphonates in
Download or read book Comprehensive Dissertation Index written by University Microfilms International and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 1984 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aromaticity in Heterocyclic Compounds written by Tadeusz Marek Krygowski and published by Springer Science & Business Media. This book was released on 2009-01-30 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. Aromaticity in Heterocyclic Compounds covers hot topics of frontier research summarized by reputed scientists in the field.
Download or read book Chiral Reagents for Asymmetric Synthesis written by Leo A. Paquette and published by John Wiley & Sons. This book was released on 2003-08-01 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros
Download or read book I All Carbon Inverse electron demand Diels Alder Reactions written by Jonathan D. Langille and published by . This book was released on 1999 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal of the Chinese Chemical Society written by Chinese Chemical Society and published by . This book was released on 1998 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Diels Alder Reaction written by Francesco Fringuelli and published by John Wiley & Sons. This book was released on 2002-01-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: 70 Jahre Forschung an der Diels-Alder-Reaktion: Dieses Buch fasst die wichtigsten und beeindruckendsten Ergebnisse in einzigartiger Weise zusammen! Zunächst werden die Grundprinzipien der Reaktion klar und verständlich anhand übersichtlicher Graphiken erläutert. Spezielle Vorschriften und gegebenenfalls ihre industrielle Umsetzung werden anschließend erklärt. Einen Schwerpunkt bilden auch physikalische und katalytische Verfahren zur Steigerung der Selektivität der Reaktion. Cycloadditionen in konventionellen und unkonventionellen Medien werden vorgestellt. Mit über 1.000 Literaturverweisen!
Download or read book Modern Applications of Cycloaddition Chemistry written by Paolo Quadrelli and published by Elsevier. This book was released on 2019-03-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes Contains the most up-to-date review of the use of pericyclic reactions in drug delivery Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area
Download or read book Frontiers in Medicinal Chemistry Volume 4 written by Atta-ur Rahman and published by Bentham Science Publishers. This book was released on 2010-12-10 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt: ""Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, incl"
Download or read book Modern Methods of Organic Synthesis written by W. Carruthers and published by Cambridge University Press. This book was released on 2004-10-14 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook on modern methods of organic synthesis.
