Download or read book Metabolic Autophagy written by Siim Land and published by Metabolic Autophagy Diet. This book was released on 2019-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermittent Fasting for Longevity and Performance Your cells are constantly monitoring the nutrient status of the cells to determine whether or not to conserve energy or to promote growth. **One of the few known ways of increasing lifespan in almost all species is caloric restriction and energy deprivation.** This triggers many metabolic pathways and processes that make the organism more adaptable to environmental stressors and thus live longer. **The metabolism has two sub-categories or sub-processes called anabolism and catabolism. ** * Anabolism, meaning 'upward' in Greek, describes the synthesis of biological molecules to build up new physical matter in the body. * Catabolism, meaning 'downward' in Greek, describes the breaking down of biological molecules to release energy. This can apply to the breakdown of bodily tissue as well as the digestion of food that then gets assimilated into the body through anabolic processes. In addition to 'Metabolic', you can also find another word in the title - 'Autophagy', which translates from Ancient Greek into 'self-devouring' or 'eating of self'. This is central to the main practice of this book. By maintaining a balance between anabolism and catabolism, you can effectively extend your lifespan. The process of autophagy entails your healthy cells devouring the old, worn-out, weak ones and converting them back into energy. It's literally your body eating itself and using that to maintain homeostasis. There are many longevity-boosting benefits to this as illustrated in virtually all other species. This book is a collection of guidelines about the principles of the anabolic-catabolic cycles in regards to nutrition and exercise. It's definitely not a panacea - a solution or remedy for all conditions and circumstances. Instead, it's a very specific protocol that's not supposed to apply for all situations. **Metabolic Autophagy will teach you:** * What increases lifespan in humans and other species * Why there's so much disease and obesity in society * How to promote health and longevity with intermittent fasting * What is Autophagy and how it works * How to age slower and be vigorous throughout your life * Which foods make you live longer and build muscle * How the nutrient regulators of mTOR, AMPK, sirtuins, FOXO proteins, hormesis and others affect longevity * What are circadian rhythms and how they affect your health * Metabolic Autophagy Foods list and their anabolic-catabolic score * Supplements that support muscle growth and longevity * Many extras and bonuses in regards to food and exerciseSiim Land is a best-selling author, anthropologist, entrepreneur, high-performance coach and a biohacker who writes about optimizing health and human performance.This book incorporates daily lifestyle and dietary practices that help to cross the chasm between longevity and high performance.

Download or read book Autophagy Book written by Beverly Johnson and published by . This book was released on 2021-01-24 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: These days, however, many of us go about life without much regard to what we eat and how we eat. It is little wonder our bodies become easy targets for all sort of diseases and, worst of all, we do not get to enjoy a long life. Inside, you will learn: - What is autophagy and how it works - Foods that will make you live longer - How you can stimulate autophagy - How autophagy can help you lose weight - Which fasting method is right for you - Why autophagy is important - And many more.. It makes tоtаl sense thаt оur bоdу needs an internal clean uр tо detox аnd rераirѕ itself. Autорhаgу dеѕtrоуѕ раrtѕ оf thе cell, рrоtеinѕ, аnd сеll mеmbrаnеѕ which аrе not funсtiоning соrrесtlу.

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Download or read book Autophagy written by Daniel Klionsky and published by CRC Press. This book was released on 2003-12-15 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen

Download or read book An Overview Of Autophagy written by Reva Koong and published by . This book was released on 2021-06-10 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you ever wondered about the secret to living a long life? Are you tired of constantly looking for the right diet, exercise routine and prescription drugs to make you look and feel good? Then keep reading. In this book, you will discover: - What Is Autophagy? - Autophagy Mechanism - Autophagy Regulation - Autophagy Types (Macro and Micro Autophagy) - The Benefits of Autophagy - The Risk of Autophagy - How To Activate Autophagy - Role of Autophagy in Cellular Processes - How Long Do You Fast for Autophagy? - The process to Initiate Autophagy - Relationship between Autophagy and Ketosis - Relationship between Autophagy and Intermittent Fasting - Autophagy and Ketogenic Diet - Autophagy and Intermittent Fasting Take control of your life and show your friends and family that there is a simple way to lose weight and be happy. Scroll up, click the "Buy" button now, and begin your journey to a fitter, leaner, and stronger you!

Download or read book Autophagy written by Thomas Hawthorn and published by scott m ecommerce. This book was released on 2019-06-24 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how a one day starvation secret won the nobel prize. And how you can use it to lose weight and promote long-term health. In 2016, Yoshinori Ohsumi won the Nobel Prize for his research on Autophagy. Now, not only does autophagy have lifechanging weight loss benefits… It may help treat cancer and neurodegenerative diseases like Alzheimer’s. Why has this unique type of fasting only become established in the past couple of years? It’s simple, the fat cats of our food industry establishment have billions riding on the outdated “3 square meals a day” lifestyle. And not only is this typical American lifestyle outdated, it’s downright dangerous! However, there is another way. And inside this breakthrough book you’ll discover: How to lose weight faster while intermittent fasting IBS pain? You can blame this common food 5 superfoods you can find at your local supermarket How inflamed is your body right now? Exactly what to ask your doctor to find out the truth. How to increase autophagy without fasting for several days in a row 7 best foods for nurturing gut health Eat this “forgotten food” to reverse plaque build up in your arteries How to properly do a water fast without feeling weak or getting hungry. A handful of this food cuts risk of heart disease by 24% 1 in 4 supplements failed quality tests at a leading independent lab. Discover which ones to throw out How to lose weight without working out every day 3 beginner mistakes which actually prevent autophagy, and how to avoid them Do you get autophagy during 16/8 fasting? The surprising truth …and much, much more. Plus countless other health secrets… Including this “miracle beverage” which researchers at the University of Minnesota found lowered diabetes risk by 33%... drinking this also boosts the effectiveness of your fast… plus one drink to avoid which sneakily breaks your fast You’ll also discover How to avoid starvation mode while fasting The raw truth about extended water fasting Is too much autophagy bad? Get the answer from the world’s leading expert Why do dogs who eat 1 meal a day live 20% longer than dogs who eat 3 meals a day? The 3 benefits of autophagy you probably didn’t know about Autophagy success stories – how one obese Mom lost 90lbs in less than 6 months and cured her diabetes All written in plain English. So you don’t need a medical degree to understand and apply what’s inside. This is not just a diet fad. This is a long-term gamechanger in the health and longevity space. Here’s the deal. The traditional “calories in, calories out” weight loss method no longer works. And restrictive low-fat or vegan diets often leave you hungry and irritable. However, when you combine the keto diet with a 2016 Nobel Prize winning breakthrough known as autophagy – you get the keto diet on steroids So take control of your life and show your friends and family that there is a simple way to lose weight and be happy – scroll up and click “add to cart”

Download or read book Autophagy and Intermittent Fasting 2 Books in 1 written by Patricia Cook and published by . This book was released on 2020-02-18 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2 Books in 1 - Autophagy & Intermittent Fasting for WomenAre you tired of constantly following a new diet, trying new exercise routines and maybe even taking prescription drugs to make you look and feel good?Do you want to feel amazing and understand the way your body functions deep down on a cellular level?Have you ever wondered about the secret to living a long and full life, free from disease and other ailments? Many of us go about our day-to-day lives without much regard to what we are eating and when we eat it. It is little wonder our bodies become easy targets for all sorts of diseases meaning we do not get to enjoy a long and full life. The good news is that with the practice of autophagy and intermittent fasting you can stimulate your body to clean out damaged cells and regenerate new ones that will be stronger and more resistant to diseases. If you're ready to enhance the performance of your body and promote the health of every cell in it, this is the ideal book for you. The best part is that you are not ingesting any drug or following some strict diet. IN THIS BOOK YOU WILL FIND: -The ways in which you can activate autophagy safely in your body. -The concepts of microautophagy and macroautophagy -How to activate autophagy via exercise, fasting and ketosis -The role of water in fasting when reaching ketosis -Misconceptions about autophagy demystified -How long and how to fast before autophagy sets in -Lifestyle and food choices that will help activate autophagy -Mistakes to avoid when practising autophagy -How to loose the correct amount of fat for your body -Information on how this practice prevents diseases -The anti-aging benefits of autophagy -The advantages to your mental health and cognitive performance -How autophagy will spirituality enhance your whole being -Suggestions for improved physical fitness and digestive system This manual is for everyone who values their life and health. It is for the young and old who value healthy living and would like to keep their bodies and immune systems resilient. Scroll to the top of the page and click the "buy now" button!

Download or read book Autophagy written by Melany Flores and published by . This book was released on 2019-09 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you curious about the process of metabolic autophagy and how it can affect the well-being of your life? Autophagy is a natural process your cells go through every day - it is an essential cleansing ritual that rids your cells of old or damaged organelles and proteins as well as pathogens and cell debris. This process's impact on cellular health has incredible implications, including: Protectionfrom cancer by destroying cancerous cells and promoting the growth of healthy cells instead, A reduced risk of neurodegenerative disorders such as Alzheimer's, A reduced risk as well as treatment of muscular disorders such as lysosomal disease, liver disease and inflammation. However, the most impressive benefits of autophagy are its ability to treat obesity by promoting weight loss as well as its anti-aging properties. Approximately 30% of people worldwide suffer from obesity, and this complex disease can cause a whole host of other health problems such as heart disease, diabetes and even cancer. It is therefore a serious problem to which autophagy is a solution. Autophagy can also increase your lifespan by counteracting against the processes that cause aging. Autophagy is typically induced when your cells undergo stress, be it environmental or physiological stress. There are four main ways to expose your cells to this type of stress so that autophagy can be promoted and its benefits can be reaped. The first method is calorie restriction, whether by following a keto diet, a fasting schedule that is intermittent or periodic, or restricting your protein intake. Exercising regularly and practicing high-intensity training, consuming autophagy-promoting foods and supplements, and getting quality sleep are the other three methods. All these methods create an internal environment in which autophagy is favored. Understanding the autophagic process - how it works, when it is triggered, how it is regulated, the effects it has on the body, etc., - is a topic that has only recently been seriously broached in the scientific world. After all, its mechanism of action was only completely elucidated in 2016. Although there are still some questions that are yet to be answered regarding this process, it is clear that it confers a vast amount of benefits to the human body. This book covers the mechanism and effects of autophagy, the diseases that can develop when it is disrupted, the benefits of promoting it and an overview of the current clinical approaches in inducing this process. We will also teach you how to utilize the autophagic process so you can lose weight and improve your health. The best part is, you won't need to take any drugs as autophagy is an entirely natural process! You'll basically be fine-tuning your body to function at its most efficient level. So, if you are interested in living a long life of the highest quality, this book contains the information that you need. It certainly provides a comprehensive overview on the science behind the process of autophagy and clearly outlines how you can harness its power to improve your quality of life. Continue reading!... Buy the Paperback version of this Book and get the E-Book for FREE

Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

Download or read book Plant Programmed Cell Death written by Arunika N. Gunawardena and published by Springer. This book was released on 2015-10-08 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Programmed cell death (PCD) is a genetically encoded, active process which results in the death of individual cells, tissues, or whole organs. PCD plays an essential role in plant development and defense, and occurs throughout a plant’s lifecycle from the death of the embryonic suspensor to leaf and floral organ senescence. In plant biology, PCD is a relatively new research area, however, as its fundamental importance is further recognized, publications in the area are beginning to increase significantly. The field currently has few foundational reference books and there is a critical need for books that summarizes recent findings in this important area. This book contains chapters written by several of the world’s leading researchers in PCD. This book will be invaluable for PhD or graduate students, or for scientists and researchers entering the field. Established researchers will also find this timely work useful as an up-to-date overview of this fascinating research area.

Download or read book Autophagy written by Alaina W. Bolton and published by . This book was released on 2020-07-26 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oncoimmunology written by Laurence Zitvogel and published by Springer. This book was released on 2017-12-13 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.

Download or read book Autophagy and Senescence in Cancer Therapy written by and published by Academic Press. This book was released on 2021-04-13 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more. Addresses the relationship between autophagy and senescence in cancer therapy Covers autophagy and senescence in tumor dormancy Explores autophagy and senescence in disease recurrence

Download or read book Intuitive Fasting written by Dr. Will Cole and published by Rodale Books. This book was released on 2021-02-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • “Dr. Will Cole clearly cares about his patients’ health, and he addresses the widespread misconceptions about intermittent fasting while giving readers a tailored week-by-week plan to get back in touch with what their body truly needs.”—Mark Hyman, MD, director, the Cleveland Clinic Center for Functional Medicine and author of Food “Intuitive Fasting makes both the science and user-friendly application of this exciting approach to human nutrition available for everyone.”—David Perlmutter, MD, FACN, author of Grain Brain and Brain Wash The most effective and achievable guide to intermittent fasting, outlining a unique plan that merges the science behind fasting with a holistic approach to eating, from the bestselling author of Ketotarian and The Inflammation Spectrum For some, the idea of fasting by eating only one or two meals a day sounds like an extreme and overly restrictive dieting tactic. But the truth is, our daily eating schedule—three meals a day, plus snacks—does not necessarily reflect our bodies’ natural cycles. In fact, eating three meals every day can cause metabolic inflexibility, which can lead to inflammation, fatigue, and chronic health problems. For millions of years, our bodies have actually functioned best with periodic times of fasting. With his fresh new approach to fasting, bestselling author and functional medicine expert Dr. Will Cole gives you the ability to take control of your hunger and make intermittent fasting intuitive. You’ll get in touch with your instinctive eating patterns and become healthier and more mindful about how and when you eat. Intuitive Fasting will show you how to find metabolic flexibility—and once you’ve reached it, you can trust your body to function at optimal capacity, whether you’ve eaten six minutes ago or six hours ago. During his 4-Week Flexible Fasting Plan, Dr. Cole will guide you through varying intermittent fasting windows, with each week of the plan tailored to focus on a different aspect of your health. He illustrates the most effective ways to fast and eat to amplify the health benefits of intermittent fasting, balancing rest and repair with clean, nutrient-dense, delicious foods. By the end of the four weeks, you will have all the tools necessary to: • Reset your body • Recharge your metabolism • Renew your cells • Rebalance your hormones Along with more than 65 recipes, you’ll also find a maintenance plan, so you can adapt fasting and feeding windows to work sustainably with your lifestyle.

Download or read book Exercise Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Download or read book Cellular Migration and Formation of Neuronal Connections written by and published by Academic Press. This book was released on 2013-05-06 with total page 1081 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity

Download or read book Superfuel written by Dr. James DiNicolantonio and published by Hay House, Inc. This book was released on 2018-11-13 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times best-selling author Dr. Joseph Mercola teams up with cardiovascular expert Dr. James J. DiNicolantonio to cut through the confusion about how dietary fats affect our bodies--and set the record straight on how to eat for optimal health. Should you cook with coconut oil or vegetable oil? Eat butter, cream, or olive oil? Supplement with fish oil or flax oil? Sometimes it seems as if everyone has a different opinion on these crucial questions--but this book holds real answers. Best-selling author and teacher Dr. Joseph Mercola teams up with cardiovascular expert Dr. James DiNicolantonio to cut through the confusion about how dietary fats affect our bodies and set the record straight on how to eat for optimal well-being. Dr. DiNicolantonio, an internationally known and respected scientist, has spent nearly a decade studying the effects of different fats on the body. Dr. Mercola is one of the world's leading authorities on natural health. In Superfuel, they've gathered a wealth of information and insight in a form that's both impeccably researched and highly accessible. You'll read about: * The many health problems supposedly caused by saturated fat--that actually aren't * Why the so-called healthy vegetable oils are actually making you sick and fat * The optimal ratio of omega-3 to omega-6 fats in your diet * Foods that help resolve inflammation, increase longevity, and fight or prevent chronic illness * A cyclical ketogenic eating plan that keeps your body burning fat as healthy fuel * Supplemental fats such as fish oil, krill oil, and flax oil--what to take and how to choose * Which oils you should cook with, how to use them, and why * And much more Drawing on Dr. DiNicolantonio's firsthand research at Saint Luke's Mid America Heart Institute, as well as hundreds of groundbreaking studies from the medical literature, Superfuel will give you the facts you need to optimize your fats and your health.