Download or read book The Morphant written by Cornelius Fuel and published by Troubador Publishing Ltd. This book was released on 2017-09-19 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gabriel Grant thinks he’s an ordinary 13-year old Londoner. But one day, something happens that leaves him with extraordinary abilities... Suddenly, there are people who want to use him for his powers. What is Gabriel’s connection with a monastery in the distant Himalayas? Who is the mysterious Searcher, and can he be trusted? Who – or what – is spying on Gabriel? Why have his parents suddenly disappeared? And what does all this have to do with a visiting circus? In an adventure based in the heart of London, and together with his feisty sister Ariel, Gabriel eventually finds the answer to many of his questions. Above all: what it means to be a Morphant. Already attracting 5-star reviews as an e-book, The Morphant is a page-turning coming-of-age adventure set against a backdrop of iconic London landmarks, and exploring a secret underground London world before reaching a thrilling climax inside the Channel Tunnel.
Download or read book Molecular Bases of Neurodegenerative Disorders of the Retina written by Hemant Khanna and published by Bentham Science Publishers. This book was released on 2017-08-04 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the physiology and molecular biology of the front and back regions of the eye. Specifically, the chapters of this book cover topics that explain currently less understood aspects of retinal health as well as the use of zebrafish models to understand the molecular pathogenesis of associated diseases. This includes retinitis pigmentosa, diabetic retinopathy ciliopathies in the eye, rhodopsin trafficking and associated disorders, and the biochemistry of cone defects. This book serves as a useful reference for scientists and graduate students seeking to understand protein trafficking mechanisms and metabolic control in retinal diseases.
Download or read book International Review of Cell and Molecular Biology written by Kwang W. Jeon and published by Academic Press. This book was released on 2008-09-02 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. * Authored by some of the foremost scientists in the field* Provides up-to-date information and directions for future research* Valuable reference material for advanced undergraduates, graduate students and professional scientists
Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Download or read book Integrative Physiology in the Proteomics and Post Genomics Age written by Wolfgang Walz and published by Springer Science & Business Media. This book was released on 2007-11-10 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a perception in the scientific community that the discipline of Physiology is in crisis, or at least, in a phase of profound transition and change. At the root of the problem is confusion between objectives (the biological questions to be solved) and the methods and technologies to be applied. Traditionally, ever since Claude Bernard’s concept of the “milieu interieur,” Physiology was an integrative science with the prime concern of studying regulatory mechanisms leading to adaptation and homeostasis in the presence of challenges from a dynamic internal and external environment. This study of control mechanisms can be applied on any level of fu- tion whether subcellular, cellular, and organ, but reaches its highest level of complexity with the functioning of the body as a whole and its interaction with the external environment. This involves the determination of the interaction of genetic with environmental factors and the resulting integrated body adaptation. It might seem obvious that in the pursuit of these questions any appropriate combination of techniques on any organizational level could be used. Yet the advent of molecular techniques has resulted in a preoccupation with the problems and challenges inherent in these techniques, sometimes at the expense of the original perspectives and concepts. The many new mechanisms that have been discovered at the molecular level, as well as their economical exploitation, have contributed to a climate of reductionism.
Download or read book Kidney Development and Disease written by Rachel K. Miller and published by Springer. This book was released on 2017-04-13 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.
Download or read book Avian Embryology written by and published by Academic Press. This book was released on 2011-09-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition will continue to serve as the most complete and up-to-date guide to the use of the avian embryo in studies of vertebrate development. It will include new approaches to analysis of the chick genome, gene knock-out studies using RNA interference, morpholinos, and other cutting edge techniques. As with the original edition, emphasis has been placed on providing practical guidance, highlighting potentials and pitfalls of all key cell biological and embryological techniques. *fully revised second edition *organized into basic and advanced Methods *new section on Functional Genomics
Download or read book Fish Physiology Zebrafish written by and published by Academic Press. This book was released on 2010-06-23 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge resource includes up-to-date information on zebrafish physiology and the tools used to study it, not only as a model species for studies of other vertebrates but with application for studies of human disease and aquatic toxicology. The utility of zebrafish for physiological research is based on several key features including i) a "fully" sequenced genome, ii) rapid (~3 month) generation times), iii) their capacity to produce large numbers of externally fertilized eggs, iv) optical transparency of embryos and larvae, and v) the applicability of reverse and forward genetics to assess gene function. Gene knockdown in embryos and the production of transgenic strains are now standard techniques being used to assess physiology. This book will be of keen interest not only to the typical readers of Fish Physiology but also to biomedical researchers, toxicologists and developmental biologists. Integrates and synthesizes the biology of the zebrafish under one cover Features contributions from the leading researchers in their fields Reaches a wider audience of researchers and biologists with its broad inclusion of subjects relating to zebrafish physiology
Download or read book The Long Road to Building a Head Smooth Travels and Accidents on the Journey From Patterning via Morphogenesis to Phenotype written by Kerstin Feistel and published by Frontiers Media SA. This book was released on 2022-05-09 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 2022 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/
Download or read book Spinal cord development and neural regeneration written by Lingyan Xing and published by Frontiers Media SA. This book was released on 2023-04-17 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Biotechnology Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Biotechnology Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bioelectronics. The editors have built Advances in Biotechnology Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioelectronics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cellular Metabolic Mapping by Fluorescence Lifetime Imaging Microscopy FLIM written by Long Yan and published by . This book was released on 2008 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Muscle Cells Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscle Cells—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Muscle Cells in a concise format. The editors have built Muscle Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Muscle Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Muscle Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Issues in Biological Biochemical and Evolutionary Sciences Research 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 2848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological, Biochemical, and Evolutionary Sciences Research. The editors have built Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological, Biochemical, and Evolutionary Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book The Zebrafish Disease Models and Chemical Screens written by and published by Academic Press. This book was released on 2011-09-09 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens
Download or read book Epitranscriptomics The Novel RNA Frontier written by Giovanni Nigita and published by Frontiers Media SA. This book was released on 2019-01-31 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the formulation of the central dogma of molecular biology and the later discovery of classes of non-coding RNAs, the primary focus of Genetics was essentially on variation of DNA aiming at elucidating biological pathways perturbed in diseases. Recently, extensive attention has shifted towards the study of posttranscriptional RNA modifications occurring in both protein-coding as well as non-coding RNAs, revealing a novel and finer layer of complexity in gene regulation. This, in turn, has led to the birth of the novel field of ‘Epitranscriptomics’. The recent increase of applications of high-throughput sequencing technology (HTS) has allowed the unprecedented opportunity to identify on a transcriptome-wide scale, millions of RNA modifications in human genes, counting today more than 140 distinct types such as: methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe) methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe), pseudourylation (?), deamination (e.g. A-to-I RNA editing). The scope of this Research Topic was to collect both reviews and research articles addressing the wet lab approaches and bioinformatics methodologies necessary to aid in the identification of novel RNA modifications and characterization of their biological functions. Among the articles embracing the aim of the Research Topic, we have collected four original research and methods articles, five reviews, and a technology article.
