Download or read book The Molecular Medicine of Viral Hepatitis written by Tim J. Harrison and published by Wiley. This book was released on 1997-01-24 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series is designed to bridge the gap between pure research in the biomedical sciences and its practical application in clinical medicine. The objective is to promote the understanding of the molecular basis of human physiology and disease, and new techniques for diagnosis and treatment. Primarily intended for graduate students of medicine, the books will also be of use to molecular biologists, biochemists, physiologists, pharmacologists and biotechnologists, as well as medical practitioners and technicians who seek to update their knowledge. The Molecular Medicine of Viral Hepatitis Edited by Tim J. Harrison and Arie J. Zuckerman Royal Free Hospital School of Medicine, London, UK General texts on diagnostic and clinical aspects of viral hepatitis abound. The Molecular Medicine of Viral Hepatitis focuses on those areas of research where advances are presently being mode and offers new ideas on the development of vaccines, diagnostic tests and therapeutic agents. Chapters include: The molecular biology of attenuation of hepatitis A virus Development of vaccines against hepatitis E virus infection The molecular role of hepatitis B virus in the development of hepatocellular carcinoma Genotypes and genetic variation of hepatitis C virus As such this volume will be indispensable to clinicians and researchers in virology, hepatology, microbiology, vaccinology, oncology and gastroenterology.
Download or read book Viral Hepatitis Molecular Biology Diagnosis and Control written by Isa K. Mushahwar and published by Gulf Professional Publishing. This book was released on 2004 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last forty years have witnessed the discovery of five human hepatitis viruses: hepatitis virus A, B, C, D, and E, and two related blood-borne viruses: GB virus C and TT virus. Viral Hepatitis provides a comprehensive overview of the latest developments and research studies in human viral hepatitis. Written by leading international scientists in the field, this book covers topics ranging from the history of these viruses to their molecular biology, diagnosis, epidemiology and control. It will be an invaluable reference source for hepatitis researchers, reference and diagnostic laboratories, clinicians, public health officers and graduate and medical students. Book jacket.
Download or read book Viral Hepatitis written by Arie J. Zuckerman and published by . This book was released on 1993 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses all aspects of viral hepatitis, from structure and molecular virology, and natural history and experimental models, to epidemiology, diagnosis and prevention. A section on clinical aspects covers transfusion-associated hepatitis, occupational aspects and paediatric infection.
Download or read book Viral Hepatitis written by E.A. Fagan and published by Garland Science. This book was released on 2003-12-16 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to bridge the widening rift between clinical and molecular aspects of viral hepatitis by providing an up-to-date overview of the field. The focus is practical and covers the limitations of clinical diagnosis, the interpretation of tests bas
Download or read book Molecular Biology Of Human Hepatitis Viruses written by Joao Monjardino and published by World Scientific. This book was released on 1998-05-30 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis A and B viruses have infected nearly half the current world population; and as many as 500 million people are still infected with the hepatitis B or C virus today. Hepatitis B vaccination is effective but not universally adopted and no vaccine is available against hepatitis C. Treatment is prohibitively expensive for areas of high endemicity or prevalence and not universally effective.This important and timely book covers recent advances in understanding the molecular biology of hepatitis viruses. The advances have contributed new insights into the molecular mechanisms involved in replication of genetic information and in gene expression; and have translated into diagnostics; prevention and development of antiviral drugs.
Download or read book Molecular Components of Hepatitis B Virus written by M. Feitelson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of Australia antigen and its association with type B hepatitis, molecular characterization of the components making up hepatitis B virus (RBV) have been pursued with worldwide interest. Over the past two decades, such characterization has led to the development of sensitive assays to screen and exclude contaminated units from blood banks and has recently resulted in the licensing of several RBV vaccines. That more than 200 million people worldwide are chronically infected with RBV, and that they are at a high risk for the development of chronic hepatitis and hepatocellular carcinoma, still represent formidable problems in our understanding of host-virus relationships on the molecular level. In the absence of a suitable tissue culture system, and with a very limited host range of infection, characterization of RBV on the molecular level has made remarkable progress recently with the advent of genome cloning, sequencing and expression of individual virus genes by recombinant DNA technology. The presence of hepatitis B-like viruses in an expanding number of animal hosts, and the possibility of virus replication in cells other than hepatocytes, provide great promise that future work will elucidate the molecular mechanisms operative in the various outcomes of RBV infection.
Download or read book Viral Hepatitis written by Howard C. Thomas and published by John Wiley & Sons. This book was released on 2013-07-22 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and mortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from the USA and Stephen Locarnini from Australia as Editors. They have recruited leading researchers and physicians from many countries, who have produced an authoritative account of current knowledge and research on this important infection, including new insights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viral hepatitis, including rapid advances in the diagnosis, management, treatment and prevention of a complex infection, which in the case of hepatitis B, C and D may lead to severe complications including chronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essential resource of current information for hepatologists, gastroenterologists, infectious diseases specialists and other clinicians, researchers, public health physicians and National and International Health Authorities.
Download or read book Hepatitis C Protocols written by Johnson Y. N. Lau and published by Humana. This book was released on 2013-08-21 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of hepatitis C virus by Michael Houghton and his c- leagues at the Chiron Corporation nearly years ago represented a technical tour de force of modern molecular medicine. This breakthrough not only unearthed the causative agent of non-A non-B hepatitis that had eluded the best of scientists for more than 20 years, but also was symbolic of another chapter in the changing paradigm of modern science and medicine. The re- lutionary concept of identifying a pathogen without actually visualizing or detecting it will forever redefine the way we approach pathogenesis of d- eases whose cause is unknown. It is benefitting that this discovery treads on the heels of the human immunodeficiency pandemic, and parallels the ala- ing emergence of various microbial pestilences in the world. Despite the rapid advances in our understanding of the virus, there is much remaining to learn about it. This book highlights some of the important areas yet to be unraveled. As illustrated in this book, the marriage between basic science and clinical medicine is essential in our quest for these unknowns. The last decade has focused on the fundamentals of the virus; the next decade must underscore translational research, bridging clinical medicine and basic science with re- ization of fundamental knowledge to improve prevention, diagnosis, and tre- ment of viral hepatitis C.
Download or read book Viral Hepatitis and Liver Disease written by Kusuya Nishioka and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A series of international symposia on viral hepatitis and liver disease has been held triannially, and called the "Olympics" of this research field. Our book presents the results of the eighth of these "Olympiads" which for the first time, was held in Asia (May 1993, Tokyo). Due to the rapid progress in research on both basic and clinical aspects of viral hepatitis and liver disease, the state of the art in this field is continually being updated, and our book provides a broad and in-depth survey of current work. The major topics in our book include molecular biology of the five known hepatitis viruses (HAV, HBV, HCV, HDV, and HEV), clinical implications of genetic variants of HBV and HCV, interferon treatment of HCV-related liver disease, and worldwide epidemiology and control of viral hepatitis. New subjects not seen in previous books, such as genotypes of HCV, are also covered. Expanding knowledge about the heterogeneity of the HCV genome has revealed a great variety of genotypes as well as their association with host pathogenesis and their varying responsiveness to interferon therapy. The first promising results of efforts to develop a hepatitis C vaccine are also presented. Finally, compared with its predecessors, our book contains many more papers from Asian countries, where the prevalence of viral hepatitis and liver disease is the highest in the world.
Download or read book Hepatitis B Virus written by Haitao Guo and published by Humana. This book was released on 2024-08-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed new edition collects state-of-the-art methods in the fields of hepatitis B virus (HBV) molecular biology and immunology. The book features techniques for cell culture, epigenetic regulation of cccDNA transcription, epitranscriptomic modification of HBV RNA, HBV pregenomic RNA and subviral particle morphogenesis, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Hepatitis B Virus: Methods and Protocols, Second Edition serves as an ideal guide for researchers pursuing a cure for this chronic disease.
Download or read book Viral Hepatitis written by Sergey Mukomolov and published by BoD – Books on Demand. This book was released on 2011-11-07 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are a lot of important issues related to viral hepatitis studies: molecular biology of viruses, laboratory diagnostics, epidemiology, treatment etc. However, there is a number of special textbooks and monographs on the subject. Considering this fact and rather fast progress in our understanding of the problem this book focuses on the important sections of the problem immune pathogenesis of parenterally transmitted viral hepatitis and some aspects of hepatitis diagnostics. Seven chapters were prepared by several groups of researchers to share information and results of studies with specialists working in the field and persons who are interested to learn about the viral hepatitis issue. The Nobel Prize Committee (the field of physiology and medicine, 2011) awarded Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity whilst Ralph M. Steinman was awarded for his discovery of the dendritic cell and its role in adaptive immunity. We are proud to say that our book is in line with these discoveries, because 3 chapters cover the problems of innate and adaptive immune response in case of viral hepatitis.
Download or read book Chronic Viral Hepatitis written by Kirti Shetty and published by Springer Science & Business Media. This book was released on 2001-09-07 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists, clinicians, and clinical investigators comprehensively review the epidemiology, molecular virology, diagnosis, treatment, and prevention of chronic hepatitis caused by the B and C viruses. The discussion of patient management includes contributions on developing novel therapeutics, supporting patients during therapy, alternative treatments, the use of drugs in chronic viral hepatitis, liver transplantation, and pregnancy in chronic viral hepatitis. Attention is also given to the treatment of patients with concomitant autoimmune disorders, the management of HIV co-infection, and the management of HBV/HCV co-infection.
Download or read book Hepatitis Prevention and Treatment written by Joseph M. Colacino and published by Birkhäuser. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development. This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field.
Download or read book Viral Hepatitis Chronic Hepatitis B written by Resat Ozaras and published by Springer. This book was released on 2018-08-17 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents up-to-date, practically oriented information on major topics in chronic hepatitis B. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will also find guidance on the invasive and non-invasive assessment of fibrosis in HBV infection and the prevention of mother-to-child transmission of HBV. Management of chronic hepatitis B in children is considered separately, and emerging drugs that hold promise for the treatment of chronic HBV infection are discussed. Chronic Hepatitis B will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.
Download or read book Molecular Biology of the Hepatitis B Virus written by Alan McLachlan and published by CRC Press. This book was released on 1991-10-23 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of the Hepatitis B Virus presents a comprehensive account of the various molecular aspects of the life cycle of the hepatitis B virus (HBV). Topics covered include the animal model systems, sequence data on the hepadnavirus genomes, the transcripts coded for the biral genome and sequence elements involved in regulating their expression, hepadnavirus replication, and analysis of the various HBV gene products and their role in virion synthesis and assembly. Other important features of the book include its discussions of the consequences of long term exposure to hepadnavirus infection and its association with hepatocellular carcinoma, the use of recombinant technologies in the generation of second generation vaccines, and the utilization of recombinant technologies to analyze an immune mediated disease. Researchers studying hepadnaviruses will find a wealth of information in this essential reference volume.
Download or read book Models of Viral Hepatitis written by Fritz von Weizsäcker and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral hepatitis B or C is the most common cause of chronic liver disease worldwide and accounts for about 80% of all hepatocellular carcinoma cases. Thus, combating viral hepatitis remains one of the most pressing public health issues today. Animal models and cell-based systems are essential tools for addressing the many still unresolved basic and clinical problems. Experimental models are needed to better understand the viral life cycles, pathogenetic aspects and natural defense mechanisms, while preclinical models are required for evaluating novel preemptive and therapeutic strategies. This.
