Download or read book The Mammalian Carotid Body written by David J. Pallot and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to Valentin (1833) and Luschka (1862), the first description of the structure now known as the carotid body must be ascribed to a Swiss physiolo gist - Albrecht von Haller - who, in 1762, called it the ganglion exiguum. This claim, however, may be erroneous, for Tauber (1743) described a struc ture at the bifurcation on the common carotid artery and called it the ganglion minutum. Andersch (1797) reprinted the text of a study made by his father between 1751 and 1755. The original printing of this work had apparently been sold as waste paper! Andersch called the organ the ganglion intercaroticum on account of its location. He also specifically stated that the sympathetic chain, the glossopharyngeal and the vagus nerves sent branches into the organ. For a while the carotid body remained forgotten, to be rediscovered in 1833 by Mayer of Bonn who again remarked upon the branches of the sympathetic, glossopharyngeal and vagus nerves as sources of a nerve plexus which innervated the ganglion intercaroticurtl. . Valentin (1833) clearly regarded the structure as part of the sympathetic nervous system, although he too recognised that the vagus and glossopharyngeal nerves contributed conspicuously to its innervation. Thus it is evident that the anatomists of the eighteenth and early nineteenth centuries regarded the structure in the carotid bifurcation as one of the many ganglia which are interspersed in the course of the sympathetic nervous system.

Download or read book Morphofunctional and Neurochemical Aspects of the Mammalian Carotid Body written by Nikolai E. Lazarov and published by Springer Nature. This book was released on 2023-12-11 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of the book series Advances in Anatomy, Embryology and Cell Biology provides a complete and exhaustive overview of the morphofunctional organization of the mammalian carotid body, a polymodal chemosensory organ responsible for the maintenance of blood gas homeostasis. The authors review the state of the art of the neurochemical anatomy of carotid body ́s cell populations with a special reference to their structural and neurochemical plasticity. The essential role of this organ in the generation, progression and maintenance of cardiorespiratory and metabolic diseases in humans and other mammals is presented. Finally, the book summarizes current knowledge on the stem cell niche in the mammalian carotid body and discusses its contribution to replacement cell therapy and other potential applications in translational research. This book represents an essential reading for physiologists, anatomists, cell, and developmental biologists, as well as physicians, veterinarians, and biomedical researchers.

Download or read book Chemoreception in the Carotid Body written by H. Acker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is becoming traditional that periodically those of us interested in the carotid body hold an international meeting to discuss their results. In 1966 a meeting was organized by R. W. Torrance in Oxford and in 1973 by M. J. Purves in Bristol; in 1974 A. S. Paintal organized a satellite symposium of the Physiological Congress in Kashmir. The organizers of these meetings are to be commended for their efforts in publishing both the papers and discussions. At these meetings it has become apparent that the direction of research is becoming more sharpely focused on the cellular mechanisms of chemoreception. During the meeting in Dortmund the papers dealt mostly with the different cell types in the carotid body and their environment, i. e. , local P0 and local flow. These included 2 light and electron microscopic studies of the morphometric and histochemical pro perties of the different cells, microelectrode studies of the glomoid tissue to understand the conversion of a chemical stimulation into nervous activity, as well as strictly bio chemical and physiologic investigations concerning the dependence of the chemo receptive process on O consumption and the turnover of catecholamines. In spite 2 of the variety in methodology, it was apparent that all contributors had a common interest: to understand the mechanisms of chemoreception. Although at the meeting itself there was ample time to fully discuss the various papers, it has become necessary here to shorten the papers and discussions; otherwise the cost of publication would have been prohibitive.

Download or read book The Comparative Morphology of the Carotid Body and Carotid Sinus written by William Edgar Adams and published by . This book was released on 1958 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oxygen Sensing written by and published by Elsevier. This book was released on 2004-05-10 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

Download or read book The Arterial Chemoreceptors written by Yoshiaki Hayashida and published by Springer Science & Business Media. This book was released on 2006-04-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.

Download or read book The Development of the Human Carotid Body written by James Dixon Boyd and published by . This book was released on 1937 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Biogenic Amines in the Carotid Body written by Hans Alfes and published by . This book was released on 1977 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Biogenic Amines in the Carotid Body written by H. Alfes and published by . This book was released on 1977 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Carotid Body Chemoreceptors written by Constancio Gonzalez and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Peripheral Arterial Chemoreceptors written by M. J. Purves and published by CUP Archive. This book was released on 1975-06-19 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Maturation of the Carotid Body Oxygen sensor During Rat Development written by Julia Paulet and published by . This book was released on 2012 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carotid bodies (CB) are paired, oxygen-sensing organs located in the bifurcation of the carotid artery that act as peripheral chemoreceptors in the detection of hypoxic, hypercapnic and acidotic levels in the arterial blood. CBs respond to these fluctuations in blood gases by initiating firing of the carotid sinus nerve. This ultimately results in the appropriate ventilatory change to restore blood gases to their physiological levels. Studies have shown that the hypoxic response of the carotid body in juvenile mammals is low, but as maturation occurs this response is strengthened and clearly exhibited in adults. One theory suggests mitochondria play a vital role in the oxygen sensitivity of Type I cells in carotid bodies. The experimental hypothesis of this project is that mitochondria in the oxygen sensing Type I cells of rat carotid bodies change in number and /or distribution during the development of the acute hypoxic ventilatory response. Type I cells were isolated from juvenile (4-6 days) and mature (14-16 days) rat carotid bodies and loaded with mitotracker to quantify mitochondrial content. Data obtained demonstrated a significant reduction in the total volume of mitochondria in Type I cells during development which was not paralleled by a fall in metabolic rate, indicating an increase in the rate of mitochondrial oxidative phosphorylation. These findings suggest that change in mitochondrial content during the development of the hypoxic response might be crucial for this mechanism's development.

Download or read book Chemoreceptors in Respiratory Control written by J. A. Ribeiro and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: List of Participants 1 Hypoxia-Induced Intermitochondrial Junctions in the Rabbit Carotid-Body : An Ultrastructural and Experimental Study. A. VERNA. N. TALIB and A. BARETS. 11 Ultrastructural Studies of the Cat Carotid Body Perfused for Short Periods with Physiological Saline Solutions. R.G. O'REGAN. M. KENNEDY. D. COTTELL and S. FEELY. Morphological and Biochemical 19 Characteristics of the Laryngeal Nerve paraganglia. A. DAHLQVIST. S. HELLSTROM. B. CARLSOO. J.M. PEGUIGNOT and S. DOMEIJ. 29 Central Terminations of Carotid Body Chemoreceptor Afferents. D. JORDAN. S. DONOGHUE. R.B. FELDER and K.M. SPYER. 39 Vascular Geometry of Arterial Chemoreceptors: Learning about the Caritud Body by Studying paraganglia of the Superior Laryngeal Nerve D. M. McDONALD and AMY HASKELL. Altered Function of Cat Carotid Body 50 Chemoreceptors in Prolonged Hyperoxia. S. LAHIRI. E. MULLIGAN. A. MORASHI. S. ADNRONIKOU and M. SHIRAHATA. 59 Glycolysis as a Link for Chemoreception? MARCO A. DELPIANO. Spectrophotometric Studies on Carotid 69 Body Tissue. H. ACKER. C. EYZAGUIRRE. ATP Content in the Cat Carotid Body 78 under Different Experimental Conditions. Support for the Metabolic Hypothesis. A. onESO. L. AL~ffiRAZ and C. GONZALEZ. 91 pathways for Calcium Entry into Type I Cells: Significance for the Secretory Response. A. OBESO. S. FIDONE and C. GONZALEZ. Effects of Cyanide and Acetylcholine on 99 Extracellular K+ and Ca++ Activities in the Cat Carotid Body. R.G. O'REGAN and H. ACKER. Application of the Chemiluminescent 108 Method to Carotid Body for Detecting Choline and Acetylcholine. ARCADI GUAL and JORDI HARSAL.

Download or read book Arterial Chemoreception written by Carlos Eyzaguirre and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book entitled Arterial Chemoreception is an edited compilation of the oral communications and posters presented at the IXth International Sym posium on Arterial Chemoreceptors held in Park City, Utah, from August 29th to September 3rd, 1988. The Symposium also saw the formal inau guration and first meeting of the International Society for Arterial Che moreception (ISAC). In all there were 87 presentations by 108 scientists from 18 countries. Authors making multiple presentations at Park City combined their results into single, longer papers for this volume. As a result this vol~me offers the reader 63 contributions of state-of-the-art research in this important and exciting field. Inasmuch as oxygen is the substrate sine qua non for the survival of all higher organisms, it is quite understandable that considerable interest sur rounds investigations into mechanisms responsible for detecting dwindling oxygen supplies in the organism. This interest has intensified as the newer techniques of cell, sub-cell, and molecular biology have become available. As detectors of insufficient oxygen in the arterial blood the arterial che moreceptors (carotid and aortic bodies) initiate many cardiopulmonary reflexes geared toward maintaining constant the delivery of oxygen to the tissues. These chemoreceptors, which also trigger secretions from the ad renal glands, are located near the carotid sinus and in the arch of the aorta.

Download or read book Arterial Chemoreceptors written by Ronan G. O'Regan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society for Arterial Chemoreception (ISAC) was founded in August 1988 during the 9th International Symposium on Arterial Chemoreception which was held at Park City, Utah, USA. ISAC was established with the aim of providing a framework to support the increasing number of investigators from a wide variety of disciplines (anatomists, pathologists, respiratory physiologists and clinicians, high altitude physiologists, biochemists, biophysicists, physiologists and pharmacologists) who share a common interest in arterial chemoreception. ISAC took over the co-ordination of the international chemoreceptor meetings, with the membership deciding the venue for forthcoming meetings. During the Park City symposium Dublin was selected to host the 1993 meeting, under the Presidency of Professor Ronan O'Regan. The 12th International Meeting on Arterial Chemoreception, which was held in Dublin in August 1993, was acclaimed as a great success by all those present. The delegates not only shared in a wide-ranging feast of chemoreceptor based science, they had plenty of opportunity during the meeting for renewing acquaintances and establishing new friendships. The location for the meeting at University College Dublin's modem Belfield campus helped to promote such interaction, and the social programme was outstanding.

Download or read book Stimulus Response Coupling in the Carotid Body written by Andrew Phillip Stephen Holmes and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Arterial Chemoreceptors in Physiology and Pathophysiology written by Chris Peers and published by Springer. This book was released on 2015-08-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds, UK during the summer of 2014. As such this volume represents a unique collection of state of the art reviews and original, brief research articles covering all aspects of oxygen sensing, ranging from the molecular mechanisms of chemotransduction in oxygen sensing cells such as the carotid body type I cells, to the adverse, reflex cardiovascular outcomes arising from carotid body dysfunction as seen, for example, in heart failure or obstructive sleep apnoea. This volume will be of tremendous interest to basic scientists with an interest in the cellular and molecular biology of oxygen sensing and integrative, whole organism physiologists as well as physicians studying or treating the clinical cardiovascular consequences of carotid body dysfunction.