Download or read book Sustained and Controlled Release Drug Delivery Systems written by Joseph R. Robinson and published by . This book was released on 1978 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Directory of Economic Research in Mississippi written by and published by . This book was released on 1971 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oral Lipid Based Formulations written by David J. Hauss and published by CRC Press. This book was released on 2007-06-08 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem

Download or read book Biomedical Applications of Nanoparticles written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-02-28 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. - Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view - Presents the recent progress related to nanotherapeutics in the oral cavity - Provides the recent progress in the field of biomedical nanoparticles

Download or read book Drug Bioavailability written by Han van de Waterbeemd and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so-called bioavailability. Written by an international team from academia and the pharmaceutical industry, this book covers all aspects of the oral bioavailability of medicines. The focus is placed on methods for determining the parameters relevant to bioavailability. These range from modern physicochemical techniques via biological studies in vitro and in vivo right up to computer-aided predictions. The authors specifically address possibilities for optimizing bioavailability during the early screening stage for the active substance. Its clear structure and comprehensive coverage make this book equally suitable for researchers and lecturers in industry and teaching.

Download or read book Drug Delivery Systems written by Vasant V. Ranade and published by CRC Press. This book was released on 2003-08-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both

Download or read book Nanoemulsions written by Seid Mahdi Jafari and published by Academic Press. This book was released on 2018-02-24 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoemulsions: Formulation, Applications, and Characterization provides detailed information on the production, application and characterization of food nanoemulsion as presented by experts who share a wealth of experience. Those involved in the nutraceutical, pharmaceutical and cosmetic industries will find this a useful reference as it addresses findings related to different preparation and formulation methods of nanoemulsions and their application in different fields and products. As the last decade has seen a major shift from conventional emulsification processes towards nanoemulsions that both increase the efficiency and stability of emulsions and improve targeted drug and nutraceutical delivery, this book is a timely resource. - Summarizes general aspects of food nanoemulsions and their formulation - Provides detailed information on the production, application, and characterization of food nanoemulsion - Reveals the potential of nanoemulsions, as well as their novel applications in functional foods, nutraceutical products, delivery systems, and cosmetic formulations - Explains preparation of nanoemulsions by both low- and high-energy methods

Download or read book Oral Delivery of Therapeutic Peptides and Proteins written by Puneet Tyagi and published by Elsevier. This book was released on 2022-08-15 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource. Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems Examines developing technologies to improve future oral bioavailability Includes the in vitro and preclinical techniques needed for development

Download or read book Excipient Development for Pharmaceutical Biotechnology and Drug Delivery Systems written by Ashok Katdare and published by CRC Press. This book was released on 2006-07-28 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.

Download or read book Lymphatic Transport of Drugs written by William N. Charman and published by CRC Press. This book was released on 1992-04-22 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphatic Transport of Drugs provides a thorough review of the determinants that affect the uptake and delivery of drugs and xenobiotics to the lymphatics. Factors affecting the transport and delivery of lipophilic drugs through the lymph after oral administration, lymphatic transport of polar drugs and macromolecules after gastrointestinal dosing, transport of drugs into the lymph after parenteral administration, and particulate drug delivery systems are among the topics examined in this volume. Lymphatic Transport of Drugs is primarily intended for pharmaceutical scientists who are attempting to alter the delivery of current therapeutic agents through formulation of prodrugs, as well as for researchers designing new drugs for lymph delivery.

Download or read book Excipient Applications in Formulation Design and Drug Delivery written by Ajit S Narang and published by Springer. This book was released on 2015-10-07 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective fields, which affords truly in-depth perspective into a spectrum of excipient-focused topics. This book captures current subjects of interest – with the most up to date research updates – in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike.

Download or read book Long Acting Injections and Implants written by Jeremy C. Wright and published by Springer Science & Business Media. This book was released on 2012-01-29 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability. An intriguing variety of technologies have been developed to provide long acting injections and implants. Many considerations need to go into the design of these systems in order to translate a concept from the lab bench to actual therapy for a patient. This book surveys and summarizes the field. Topics covered in Long Acting Injections and Implants include the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), specific implantable technologies (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine delivery, sterilization, drug release testing and regulatory aspects of long acting injections and implants. This volume provides essential information for experienced development professionals but was also written to be useful for scientists just beginning work in the field and for others who need an understanding of long acting injections and implants. This book will also be ideal as a graduate textbook.

Download or read book Skin Permeability written by H. Schaefer and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dosage Form Design Considerations written by and published by Academic Press. This book was released on 2018-07-28 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Download or read book Cosmetic and Pharmaceutical Applications of Polymers written by T. Cheng and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers continue to show almost amazing versatility. We have always known that polymers could be used for trinkets, toys and dishes. Now, however, we are no longer surprised to encounter these adaptable mate rials in almost every place we look. We find them in our cars, tools, electronic devices, building materials, etc. The use of polymeric mate rials in medicine is also well documented in previous books by one of the Editors (Gebelein) and by others. Likewise, the use of polymeric mate rials in pharmaceutical applications, especially in controlled release systems, is also well established. Nevertheless, the use of these ubiquitous chemicals is far less ob vious in the field of cosmetics, although modern cosmetic preparations rely heavily on polymers and this trend is certain to increase. This book brings together much of the basic information on polymers in cosmetics and compares this usage with similar applications in pharmaceutical and medical applications. Cosmetics, like medicine and pharmacy, dates back to antiquity. We can find uses of perfumes, balms and ointments in various old books, such as the Bible. For example, the use of ointments and balms is noted more than thirty eight times, and perfumes and related materials are cited at least twenty nine times in the Bible.

Download or read book Human Pharmaceuticals Hormones and Fragrances written by Thomas Ternes and published by IWA Publishing. This book was released on 2007-01-30 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The observed concentrations of pharmaceuticals and personal care products (PPCPs) in raw wastewater confirm that municipal wastewater represents the main disposal pathway for the PPCPs consumed in households, hospitals and industry. In sewage treatment plant effluents most PPCPs are still present, since many of these polar and persistent compounds are being removed only partially or, in some cases, not at all. Treated wastewater therefore represents an important point source for PPCPs into the environment. After passing a sewage treatment plant the treated wastewater is mostly discharged into rivers and streams or sometimes used to irrigate fields. If drinking water is produced using resources containing a substantial proportion of treated wastewater (e.g. from river water downstream of communities) the water cycle is closed and indirect potable reuse occurs. Human Pharmaceuticals, Hormones and Fragrances provides an overview of the occurrence, analytics, removal and environmental risk of pharmaceuticals and personal care products in wastewater, surface water and drinking water. The book covers all aspects of the fate and removal of PPCPs in the whole water cycle: consumption and occurrence, analytical methods, the legal background, environmental risk assessment, human and animal toxicology, source control options, wastewater and drinking water treatment as well as indirect reuse. The book presents a summary of the results obtained during the EU project "Poseidon", combined with further expert knowledge on the field, and is written at a level appropriate for professionals involved in management of water resource quality. Professionals in the field including decision makers, engineers and scientists, as well as students entering the field, will find this an invaluable source of information. First comprehensive study on the assessment, fate and removal of pharmaceuticals and personal care products in wastewater and drinking water treatment. Emphasises the importance of micropollutants in the water cycle, provides methods for quantifying their fate and technologies for their removal.

Download or read book Targeted Delivery of Pesticides Using Biodegradable Polymeric Nanoparticles written by Arnab De and published by Springer Science & Business Media. This book was released on 2013-11-18 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brief is the first to focus exclusively on environmentally friendly delivery of pesticides (controlled-release nanoparticulate formulation of pesticides using biodegradable polymers as carriers). The brief also introduces pesticides like Chlorpyrifos and biodegradable polymers like guar-gum. The brief will be extremely useful to the researchers in the field of agrochemicals and will be equally useful for advanced professionals in the field of biology, chemistry, environmental biology, entomology and horticulture.