Download or read book The Global Threat of Carbapenem Resistant Gram Negative Bacteria written by Milena Dropa and published by Frontiers Media SA. This book was released on 2022-09-12 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The global threat of carbapenem resistant gram negative bacteria volume II written by Ziad Daoud and published by Frontiers Media SA. This book was released on 2023-05-24 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carbapenemases in Gram negative Bacteria A Global Health Threat and Therapeutic Challenge written by Mullika Traidej Chomnawang and published by Frontiers Media SA. This book was released on 2022-06-27 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level written by World Health Organization and published by . This book was released on 2017-01-31 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health care-associated infections (HAI) are one of the most common adverse events in care delivery and a major public health problem with an impact on morbidity, mortality and quality of life. At any one time, up to 7% of patients in developed and 10% in developing countries will acquire at least one HAI. These infections also present a significant economic burden at the societal level. However, a large percentage are preventable through effective infection prevention and control (IPC) measures. These new guidelines on the core components of IPC programmes at the national and facility level will enhance the capacity of Member States to develop and implement effective technical and behaviour modifying interventions. They form a key part of WHO strategies to prevent current and future threats from infectious diseases such as Ebola, strengthen health service resilience, help combat antimicrobial resistance (AMR) and improve the overall quality of health care delivery. They are also intended to support countries in the development of their own national protocols for IPC and AMR action plans and to support health care facilities as they develop or strengthen their own approaches to IPC. These are the first international evidence-based guidelines on the core components of IPC programmes. These new WHO guidelines are applicable for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.
Download or read book Rising Plague written by Brad Spellberg, M.D. and published by Prometheus Books. This book was released on 2009-12-04 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spellberg's book is a powerful and compelling journey into the antibiotic resistance problem . . . [written] in a personal, compelling, and easy-to-understand manner. It's a must read.--Michael Osterholm, M.D., author of "Living Terrors."
Download or read book Global Dissemination and Evolution of Epidemic Multidrug Resistant Gram Negative Bacterial Pathogens Surveillance Diagnosis and Treatment Volume II written by Fang He and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inappropriate use of antibiotics and a lack of newly developed ones are the main contributors to the current antibiotic resistance crisis. The World Health Organization (WHO) has acknowledged that bacterial antibiotic resistance represents one of the biggest threats to global public health, increasing therapy costs and mortality rates in severe infections. The leading cause of nosocomial infections globally is primarily due to a league of gram-negative bacteria that readily develop antimicrobial resistance. They frequently cause severe disease and easily ‘escape’ the activity of antibiotics. However, many unanswered questions concerning the mechanisms of global dissemination and evolution patterns of these notorious epidemic multidrug-resistant gram-negative bacterial pathogens. Thus, the time is right now to arrange a Research Topic to present and highlight novel findings in this research field. This Research Topic highlights advances in understanding antimicrobial resistance mechanisms at the molecular level and the transmission dynamics and developing new treatments for multidrug-resistant gram-negative bacteria. This Research Topic welcomes genomic epidemiological studies to explore the molecular basis of antimicrobial resistance and to discover the new channels of resistance transmission between humans, animals, and the environment to encapsulate the ‘One Health’ concept. Also, surveillance on both global and local scales focuses on both the transmission of bacteria and the genes and mobile genetic elements (MGEs) that confer antimicrobial resistance to the ‘last-resort antimicrobial agents’ heightened virulence are more than welcome. Finally, studies that attempt to identify new resistance mechanisms, explore newly discovered antimicrobial agents, and introduce new techniques and methods for rapid detection, characterization, and elimination of multidrug-resistant gram-negative bacteria would be particularly welcome.
Download or read book Antimicrobial Therapy I written by and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carbapenemases written by Saba Riaz and published by Createspace Independent Publishing Platform. This book was released on 2017-12-05 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written to present a brief overview of carbapenemases. The authors have enlightened the characteristic features, Genetic determinants, various phenotypic and molecular diagnostic procedures for detection of NBL. This book is the first effort from Pakistan which summarizes the prevalence scenario and diversity of Carbapenem variants worldwide and particularly in Pakistan. The book has mentioned the myths, pros and cons of various detection methodologies with their evolving trends according to Clinical Laboratory Standards Institute guidelines. We have covered evolution of microbial resistance which is greatly influenced by several intrinsic and extrinsic factors including hospital settings, laboratory setup, use and misuse of antibiotics and discovery of carbapenems, classification of carbapenemases, dissemination of carbapenemases through horizontal gene transfer, different criteria of classification, global occurrence of carbapenemases, carbapenemases in Pakistan. Moreover, we have discussed detection tests with their limitations including phenotypic tests which includes Imipenem (EDTA) synergy test:, Boronic acid tesr and Modified Hodge test. After that we have discussed several chromogenic media in detail for the detection of carbapenemase resistant strains. MALDI TOF MS technology is adapted in various clinical laboratories for the detection of carbapenemase resistance bacteria by detecting the carbapebemases activity. Accelerate diagnostics method which is a digital microscopy of halted alive bacteria found in broths of blood cultures are utilized identify both do susceptibility. Surpluses of reports about molecular identification tools to detect the CP genes have been published in scientific literature over the few past years. But only few of them are approved by FDA to use in diagnostic purpose, and the most of them are laboratory developed tests. PCR is applied on those cases where resistance is directly associated with genes expression level. Than we have discussed numerous pros and cons associated with any detection methods for studying confrontation mechanism in gram negative bacteria. Talking about genetic basis of Carbapenemase phenotype we have discussed Epidemiology of Carbapenems Resistant Bacteria in the globe and more specifically in our region with the distribution of different types of responsible enzymes. Genetic Basis of Carbapenemase Activity including Genetic Expression of Efflux Pumps, Genetic Suppression of Penicillin Binding Proteins, Inter-relationship of Carbapenems Resistance Mechanisms which results in such a phenotype is also discussed in details. We have also discussed several points regarding the Prevention of Carbapenems. After that we have discussed Current Scenario of Carbapenem Therapy in our hospital settings which might give us some clues regarding why this phenotype is spreading everywhere. After discussing problem we have moved towards the therapeutic options that we have left with which includes. The "antibiotic pipeline" has yielded an important new beta-lactam-beta lactamase inhibitor combination, Ceftazidime-Avibactam, which is gaining popularity now days. Polymixin B and colistin are the drug of choice for the MBL producing Gram negative bugs except those organism which are intrinsically resistant to colistin like Proteus species. Rifampicin itself is not used for treatment of Carbapenem resistant Gram negative rods due to rapid emergence of resistance. But in combination with colistin it is very effective and resistance development chances are also less in combination therapy. Different clinical trials have been conducted accessing the role of tigecycline in combination with other antimicrobials. Tigecycline-gentamicin and tigecycline-colistin combinations were proved to be more successful in clinical trials as compared to tigecycline alone. Fosfomycin in combination with colistin has proved to be a very good option against Carbapenem resistant negative bacteria.
Download or read book Resistant Rivals The Global Threat of Antibiotic Resistant Bacteria written by Zahid Ameer and published by Zahid Ameer. This book was released on 2024-10-03 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistant Rivals: The Global Threat of Antibiotic-Resistant Bacteria explores the rising danger of antibiotic resistance and its impact on global health. This in-depth book uncovers how antibiotic-resistant bacteria, also known as superbugs, have evolved to withstand modern medicine, threatening to undo decades of progress in treating infections. It delves into the history of antibiotics, the science behind bacterial resistance, and the urgent need for global awareness, new drug development, and responsible antibiotic use. Learn about the most dangerous superbugs, such as MRSA and CRE, and the economic, social, and medical consequences of this global health crisis. A must-read for anyone interested in infectious diseases, healthcare policy, and the fight against antibiotic resistance. Discover practical solutions and actions to combat one of the greatest threats to modern medicine in this informative and timely book. Perfect for healthcare professionals, students, and general readers concerned with public health.
Download or read book A Study of Sediment written by Walenty Jarocki and published by . This book was released on 1963 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
Download or read book OECD Health Policy Studies Stemming the Superbug Tide written by OECD. and published by Org. for Economic Cooperation & Development. This book was released on 2019-01-21 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial resistance (AMR) is a large and growing problem with the potential for enormous health and economic consequences, globally. As such, AMR has become a central issue at the top of the public health agenda of OECD countries and beyond. In this
Download or read book Annual Update in Intensive Care and Emergency Medicine 2011 written by Jean-Louis Vincent and published by Springer Science & Business Media. This book was released on 2011-04-02 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Annual Update compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Download or read book Challenges to Tackling Antimicrobial Resistance written by Michael Anderson and published by Cambridge University Press. This book was released on 2020-04-23 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible overview of the challenges in tackling AMR, and the economic and policy responses of the 'One Health' approach. It will appeal to policy-makers seeking to strengthen national and local polices tackling AMR, as well as students and academics who want an overview of the latest scientific evidence regarding effective AMR policies.
Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Antimicrobial Resistance in Developing Countries written by Aníbal de J. Sosa and published by Springer Science & Business Media. This book was released on 2009-10-08 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.
Download or read book Growing and Handling of Bacterial Cultures written by Madhusmita Mishra and published by . This book was released on 2019-12-04 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
