Download or read book The Forever Fix written by Ricki Lewis and published by Macmillan + ORM. This book was released on 2012-03-13 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fascinating narrative science that explores the next frontier in medicine and genetics through the very personal prism of the children and families gene therapy has touched. Eight-year-old Corey Haas was nearly blind from a hereditary disorder when his sight was restored through a delicate procedure that made medical history. Like something from a science fiction novel, doctors carefully injected viruses bearing healing genes into the DNA of Corey's eyes—a few days later, Corey could see, his sight restored by gene therapy. THE FOREVER FIX is the first book to tell the fascinating story of gene therapy: how it works, the science behind it, how patients (mostly children) have been helped and harmed, and how scientists learned from each trial to get one step closer to its immense promise, the promise of a "forever fix," - a cure that, by fixing problems at their genetic root, does not need further surgery or medication. Told through the voices of the children and families who have been the inspiration, experimental subjects, and successes of genetic science, THE FOREVER FIX is compelling and engaging narrative science that tells explores the future of medicine as well as the families and scientists who are breaking new ground every day.
Download or read book The Immortal Life of Henrietta Lacks written by Rebecca Skloot and published by Crown. This book was released on 2010-02-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
Download or read book Gene Everlasting written by Gene Logsdon and published by Chelsea Green Publishing. This book was released on 2014 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Gene Everlasting contains Logsdon's reflections, by turns both humorous and heart-wrenching, on nature, death, and eternity, all from a contrary farmer's perspective. He recounts joys and tragedies from his childhood in the 1930s and '40s spent on an Ohio farm, through adulthood and child-raising, all the way up to his recent bout with cancer, always with an eye toward the lessons that farming has taught him about life and its mysteries."--www.Amazon.com.
Download or read book The Forever Witness written by Edward Humes and published by Penguin. This book was released on 2022-11-29 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Thought-provoking true-crime thriller…the book raises urgent questions of balancing public and private good that we’ll likely be dealing with as long as the title implies.”—Wall Street Journal A relentless detective and a civilian genealogist solve a haunting cold case—and launch a crime-fighting revolution that tests the fragile line between justice and privacy. In November 1987, a young couple from the idyllic suburbs of Vancouver Island on an overnight trip to Seattle vanished without a trace. A week later, the bodies of Tanya Van Cuylenborg and her boyfriend Jay Cook were found in rural Washington. It was a brutal crime, and it was the perfect crime: With few clues and no witnesses in the vast and foreboding Olympic Peninsula, an international manhunt turned up empty, and the sensational case that shocked the Pacific Northwest gradually slipped from the headlines. In deep-freeze, long-term storage, biological evidence from the crime sat waiting, as Detective Jim Scharf poured over old case files looking for clues his predecessors missed. Meanwhile, 1,200 miles away in California, CeCe Moore began her lifelong fascination with genetic genealogy, a powerful forensic tool that emerged not from the crime lab, but through the wildly popular home DNA ancestry tests purchased by more than 40 million Americans. When Scharf decided to send the cold case’s decades-old DNA to Parabon NanoLabs, he hoped he would finally bring closure to the Van Cuylenborg and Cook families. He didn’t know that he and Moore would make history. Genetic genealogy, long the province of family tree hobbyists and adoptees seeking their birth families, has made headlines as a cold case solution machine, capable of exposing the darkest secrets of seemingly upstanding citizens. In the hands of a tenacious detective like Scharf, genetic genealogy has solved one baffling killing after another. But as this crime-fighting technique spreads, its sheer power has sparked a national debate: Can we use DNA to catch the murderers among us, yet still protect our last shred of privacy in the digital age—the right to the very blueprint of who we are?
Download or read book The Sports Gene written by David Epstein and published by Penguin. This book was released on 2014-04-29 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestseller – with a new afterword about early specialization in youth sports – from the author of Range: Why Generalists Triumph in a Specialized World. The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training? In this controversial and engaging exploration of athletic success and the so-called 10,000-hour rule, David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving it. Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press. This book was released on 2016-05-26 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Download or read book A Crack In Creation written by Jennifer A. Doudna and published by HarperCollins. This book was released on 2017-06-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY | Finalist for the Los Angeles Times Book Prize “A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “An invaluable account . . . We owe Doudna several times over.” — Guardian
Download or read book Breath from Salt written by Bijal P. Trivedi and published by BenBella Books. This book was released on 2020-09-08 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recommended by Bill Gates and included in GatesNotes "Elaborating on the science as well as the business behind the fight against cystic fibrosis, Trivedi captures the emotions of the families, doctors, and scientists involved in the clinical trials and their 'weeping with joy' as new drugs are approved, and shows how cystic fibrosis, once a 'death sentence,' became, for many, a manageable condition. This is a rewarding and challenging work." —Publishers Weekly Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday. The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease. From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.
Download or read book The Immortal Gene written by Jonas Saul and published by . This book was released on 2018-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PLAYING GOD HAS CONSEQUENCES. Jake Wood has it made. He is a tough homicide detective with a partner who's like a brother, and he's about to marry the girl of his dreams. Then Jake learns a close friend is missing and travels to South America in search of him. After a freak accident in the Amazon Rainforest, Jake wakes up in the hospital--eighteen months later. Long presumed dead, he discovers his fiancée is married and pregnant, his house was sold, his job is gone, and his partner transferred to another city to become lead detective on a serial killer case. Jake buys a cabin in the woods and tries to leave the world behind, until his home is broken into and he discovers he was targeted--but why? When Jake's former partner requests his aid in catching the Blood Eagle Killer, he offers to help find whoever is behind Jake's recent trouble. This leads to Fortech Industries, a pharmaceutical company secretly researching a way to create an immortal gene. Now they intend to destroy their only error--Jake Wood--who has become something more than human.
Download or read book My Beautiful Genome written by Lone Frank and published by Simon and Schuster. This book was released on 2011-09-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally acclaimed science writer Lone Frank swabs up her DNA to provide the first truly intimate account of the new science of consumer-led genomics. She challenges the business mavericks intent on mapping every baby's genome, ponders the consequences of biological fortune-telling, and prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century - a quest made all the more gripping as Frank considers her family's and her own struggles with depression.
Download or read book Spring Chicken written by Bill Gifford and published by Hachette+ORM. This book was released on 2016-08-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: From acclaimed journalist Bill Gifford comes a roaring journey into the world of anti-aging science in search of answers to a universal obsession: what can be done about getting old? Spring Chicken: Stay Young Forever (or Die Trying) Spring Chicken is a full-throttle, high-energy ride through the latest research, popular mythology, and ancient wisdom on mankind's oldest obsession: How can we live longer? And better? In his funny, self-deprecating voice, veteran reporter Bill Gifford takes readers on a fascinating journey through the science of aging, from the obvious signs like wrinkles and baldness right down into the innermost workings of cells. We visit cutting-edge labs where scientists are working to "hack" the aging process, like purging "senescent" cells from mice to reverse the effects of aging. He'll reveal why some people live past 100 without even trying, what has happened with resveratrol, the "red wine pill" that made headlines a few years ago, how your fat tissue is trying to kill you, and how it's possible to unlock longevity-promoting pathways that are programmed into our very genes. Gifford separates the wheat from the chaff as he exposes hoaxes and scams foisted upon an aging society, and arms readers with the best possible advice on what to do, what not to do, and what life-changing treatments may be right around the corner. An intoxicating mixture of deep reporting, fascinating science, and prescriptive takeaway, Spring Chicken will reveal the extraordinary breakthroughs that may yet bring us eternal youth, while exposing dangerous deceptions that prey on the innocent and ignorant.
Download or read book Unlock Your Muscle Gene written by Ori Hofmekler and published by North Atlantic Books. This book was released on 2011-10-04 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author of The Warrior Diet presents a revolutionary nutrition and exercise program that can improve your health, longevity, and athletic performance Provocatively written yet grounded in science, Unlock Your Muscle Gene is a revolutionary guide to physical transformation and the latest information on muscle conditioning, weight loss, and anti-aging strategies. According to Ori Hofmekler, we need to learn how to trigger the genes that retain and develop our muscles and extend our lives—we need to unleash this innate program that transforms pain to power and makes our bodies thrive. Hofmekler exposes the false theories behind modern fitness and presents the actual biological principles upon which human diet and training should be based. He also details how to combine foods; the right meal timing and meal size; why we need to separate AM foods and PM foods; the ideal fuel to prevent “hitting the wall”; how long and how often to train; and whether we can develop a super-muscle fiber hybrid with unmatched strength and durability. Unlock Your Muscle Gene will inspire you on your path to a stronger, healthier, biologically younger body.
Download or read book Fantastic Voyage written by Ray Kurzweil and published by Rodale. This book was released on 2005-09-27 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading scientist and an expert on human longevity explain how new discoveries in the fields of genomics, biotechnology, and nanotechnology could radically extend the human life expectancy and enhance physical and mental abilities, and introduce a cutting-edge program designed to enhance the immune system and slow the aging process on a cellular level. Reprint.
Download or read book The Forever Fix written by Ricki Lewis and published by Macmillan. This book was released on 2012-03-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lewis pens the first book to tell the fascinating story of gene therapy: how it works, the science behind it, how patients (mostly children) have been helped and harmed, and how scientists learned from each trial to get one step closer to the promise of a cure.
Download or read book Range written by David Epstein and published by Penguin. This book was released on 2021-04-27 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 New York Times bestseller that has all America talking—with a new afterword on expanding your range—as seen on CNN's Fareed Zakaria GPS, Morning Joe, CBS This Morning, and more. “The most important business—and parenting—book of the year.” —Forbes “Urgent and important. . . an essential read for bosses, parents, coaches, and anyone who cares about improving performance.” —Daniel H. Pink Shortlisted for the Financial Times/McKinsey Business Book of the Year Award Plenty of experts argue that anyone who wants to develop a skill, play an instrument, or lead their field should start early, focus intensely, and rack up as many hours of deliberate practice as possible. If you dabble or delay, you’ll never catch up to the people who got a head start. But a closer look at research on the world’s top performers, from professional athletes to Nobel laureates, shows that early specialization is the exception, not the rule. David Epstein examined the world’s most successful athletes, artists, musicians, inventors, forecasters and scientists. He discovered that in most fields—especially those that are complex and unpredictable—generalists, not specialists, are primed to excel. Generalists often find their path late, and they juggle many interests rather than focusing on one. They’re also more creative, more agile, and able to make connections their more specialized peers can’t see. Provocative, rigorous, and engrossing, Range makes a compelling case for actively cultivating inefficiency. Failing a test is the best way to learn. Frequent quitters end up with the most fulfilling careers. The most impactful inventors cross domains rather than deepening their knowledge in a single area. As experts silo themselves further while computers master more of the skills once reserved for highly focused humans, people who think broadly and embrace diverse experiences and perspectives will increasingly thrive.
Download or read book The Code Breaker written by Walter Isaacson and published by Simon and Schuster. This book was released on 2021-03-09 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
