Download or read book Microbial Degradation of Xenobiotics written by Shree Nath Singh and published by Springer Science & Business Media. This book was released on 2011-10-07 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs in recent years through detailed genomic, metagenomic, proteomic, bioinformatic and other high-throughput analyses of environmentally relevant microorganisms have provided us unprecedented insights into key biodegradative pathways and the ability of organisms to adapt to changing environmental conditions. The degradation of a wide spectrum of organic pollutants and wastes discharged into the environment by anthropogenic activities is an emerging need today to promote sustainable development of our society with low environmental impact. Microbial processes play a major role in the removal of recalcitrant compounds taking advantage of the astonishing catabolic versatility of microorganisms to degrade or transform such compounds. New breakthroughs in sequencing, genomics, proteomics, bioinformatics and imaging are generating vital information which opens a new era providing new insights of metabolic and regulatory networks, as well as clues to the evolution of degradation pathways and to the molecular adaptation strategies to changing environmental conditions. Functional genomic and metagenomic approaches are increasing our understanding of the relative importance of different pathways and regulatory networks to carbon flux in particular environments and for particular compounds. New approaches will certainly accelerate the development of bioremediation technologies and biotransformation processes in coming years for natural attenuation of contaminated environments

Download or read book Xenobiotics in the Soil Environment written by Muhammad Zaffar Hashmi and published by Springer. This book was released on 2017-02-15 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the vast variety of xenobiotics, such as pesticides, antibiotics, antibiotic resistance genes, agrochemicals and other pollutants, their interactions with the soil environment, and the currently available strategies and techniques for soil decontamination and bioremediation. Topics covered include: transport mechanisms of pollutants along the Himalayas; use of earthworms in biomonitoring; metagenomic strategies for assessing contaminated sites; xenobiotics in the food chain; phyto-chemical remediation; biodegradation by fungi; and the use of enzymes and potential microbes in biotransformation. Accordingly, the book offers a valuable guide for scientists in the fields of environmental ecology, soil and food sciences, agriculture, and applied microbiology.

Download or read book Plant Responses to Xenobiotics written by Anita Singh and published by Springer. This book was released on 2016-12-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is compilation of studies related with the xenobiotics i.e. chemical or other substance that is not normally found in the ecosystems and get accumulated at higher concentration in the biological system due to rampant industrialisation and urbanisation activities. This book has tried to give information on various issues to give comprehensive and concise knowledge of the recent advancement in the field of environmental xenobiotics and how it disturbs the plants metabolism. Other key features of the book are related to xenobiotic toxicity and detoxification mechanism, biochemical tools toward its remediation processes, molecular mechanism for xenobiotics detoxification and effect on metallomics. It also focuses on recent development in the field of waste water remediation concerned with the xenobiotics involvement. This book is different in such a way that it includes all the initial information along with the new researches. It includes the description of problem along with its solution. This volume describe the effects of xenobiotics at different levels i.e. biochemical, physiological and molecular, giving the details on signaling pathways to modify the responses of xenobiotics in plant system. Thus, it gives confirming crosstalk between xenobiotic effects and signalling pathways. This book includes description about both the organic contaminants such as pesticides, solvents and petroleum products as well as inorganic xenobiotics that include heavy metals, non-metals, metalloids, and simple soluble salts. Here the plant is main objective and that have to deal with these kinds of compounds either by avoiding accumulation of these compounds or by exhibiting several enzymatic reactions for detoxification including oxidation, reduction, and conjugation reactions. Affected plants exhibit several enzymatic and non-enzymatic antioxidant and other reactions for detoxification of ROS including oxidation, reduction, hydrolysis and conjugation reactions. The book focuses on different forms and sources of xenobiotics including organic and inorganic xenobiotics. The matter of this book will definitely increase the knowledge about the impacts of xenobiotics on plants system. There must be potentially broad readership who could find this fruitful for their study as well as for their research. As this book has balance between basic plant physiology and toxicity caused by the xenobiotics so it can be widely used in several disciplines. Overall, the book will bring deep knowledge in the field of xenobiotics toxicity in plants during recent years and it is definitely a compilation of interesting information which isn't fully covered elsewhere in the current market.

Download or read book Microbial Metabolism of Xenobiotic Compounds written by Pankaj Kumar Arora and published by Springer. This book was released on 2019-06-27 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenobiotic compounds including pesticides, nitrophenols, pyridine, polycyclic aromatic compounds and polychlorinated biphenyls are widely spread in environment due to anthropogenic activities. Most of them are highly toxic to living beings due to their mutagenic and carcinogenic properties. Therefore, the removal of these compounds from environment is an essential step for environmental sustainability. Microbial remediation has emerged as an effective technology for degradation of these xenobiotic compounds as microorganisms have unique ability to utilize these compounds as their sole source of carbon and energy. The primary goal of this book is to provide detailed information of microbial degradation of many xenobiotic compounds in various microorganisms.

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Download or read book Environmental Biotechnology written by Jeyabalan Sangeetha and published by CRC Press. This book was released on 2016-10-14 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: With focus on the practical use of modern biotechnology for environmental sustainability, this book provides a thoughtful overview of molecular aspects of environmental studies to create a new awareness of fundamental biological processes and sustainable ecological concerns. It covers the latest research by prominent scientists in modern biology and delineates recent and prospective applications in the sub-areas of environmental biotechnology with special focus on the biodegradation of toxic pollutants, bioremediation of contaminated environments, and bioconversion of organic wastes toward a green economy and sustainable future.

Download or read book Smart Bioremediation Technologies written by Pankaj Bhatt and published by Academic Press. This book was released on 2019-06-07 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Bioremediation Technologies: Microbial Enzymes provides insights into the complex behavior of enzymes and identifies metabolites and their degradation pathways. It will help readers work towards solutions for sustainable medicine and environmental pollution. The book highlights the microbial enzymes that have replaced many plant and animal enzymes, also presenting their applications in varying industries, including pharmaceuticals, genetic engineering, biofuels, diagnostics and therapy. In addition, new methods, including genomics and?metagenomics, are being employed for the discovery of new enzymes from microbes. This book brings all of these topics together, representing the first resource on how to solve problems in bioremediation. Provides the most novel approaches in enzyme studies Gives insights in real-time enzymology that are correlated with bioremediation Serves as a valuable resource on the use of genomes, transcriptomes and proteomes with bioremediation Refers to enzymes as diagnostic tools

Download or read book Environmental Security Assessment and Management of Obsolete Pesticides in Southeast Europe written by Lubomir I. Simeonov and published by Springer. This book was released on 2014-07-08 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work is a fine contribution to the broad field of environmental security in the context of risk assessment and management of obsolete pesticides for the region of Southeast Europe. The purpose of this book is to evaluate the existing knowledge of improper disposal of obsolete pesticides in the region, to estimate the associated impact on environmental health, and to develop recommendations to mitigate or eliminate threats posed to the environment, biodiversity and human life. The issues discussed in the book include: reviews of the transport and fate of pesticides and associated contaminated materials in different environmental media and identification of the principal sources, emission routes and patterns of environmental pollution with pesticides; a recognition of the most suitable methods for environmental sampling analysis and sample preparation; an evaluation of the current methods and techniques for chemical and mass analysis of environmental and biological samples and discussion of the metrological and quality aspects of trace analyses; a characterization of the environmental and human health impacts of pesticide pollution, the health effects associated with acute and chronic exposure and the use of epidemiological data for risk assessment; a revision of the existing chemical safety regulations and strategies for protection and management of obsolete pesticide stocks; a survey of the international conventions, directives and standards concerning pesticide use.

Download or read book Fundamentals of Toxicologic Pathology written by Matthew A. Wallig and published by Academic Press. This book was released on 2009-11-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels

Download or read book Ecotoxicology Modeling written by James Devillers and published by Springer Science & Business Media. This book was released on 2009-08-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecotoxicology Modeling is a comprehensive and well-documented text providing a collection of computational methods to the ecotoxicologists primarily interested in the study of the adverse effects of chemicals, their mechanisms of action and/or their environmental fate and behavior. Avoiding mathematical jargon, the book presents numerous case studies to enable the reader to understand the interest but also the limitations of linear and nonlinear models in ecotoxicology. Written by an international team of scientists, Ecotoxicology Modeling is of primary interest to those whose research or professional activity is directly concerned with the development and application of models in ecotoxicology. It is also intended to provide the graduate and post-graduate students with a clear and accessible text covering the main types of modeling approaches used in environmental sciences.

Download or read book Fundamentals of Ecotoxicology written by Michael C. Newman and published by CRC Press. This book was released on 2019-11-27 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is revised throughout and includes new and expanded information on natural resource damage assessment, the latest emerging contaminants and issues, and adds new international coverage, including case studies and rules and regulations. The text details key environmental contaminants, explores their fates in the biosphere, and discusses bioaccumulation and the effects of contaminants at increasing levels of ecological organization. Vignettes written by experts illustrate key themes or highlight especially pertinent examples. This edition offers an instructors' solution manual, PowerPoint slides, and supplemental images. Features: Adds all new discussions of natural resource damage assessment concepts and approaches Includes new vignettes written by leading guest authors Draws on materials from 2,500 cited sources, including 400+ new to this edition Adds numerous new entries to a useful glossary of 800+ terms Includes a new appendix discussing Brazilian environmental laws and regulations added to existing appendices outlining U.S., E.U., Chinese, Australian, and Indian environmental laws Fundamentals of Ecotoxicology: The Science of Pollution, Fifth Edition contains a broad overview of ecotoxicology and provides a basic understanding of the field. Designed as a textbook for use in introductory graduate or upper-level undergraduate courses in ecotoxicology, applied ecology, environmental pollution, and environmental science, it can also be used as a general reference for practicing environmental toxicologists.

Download or read book Toxicology and Human Environments written by Ernest Hodgson and published by Academic Press. This book was released on 2012-09-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments. The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis. Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them

Download or read book Handbook on Biodegradation and Biological Treatment of Hazardous Organic Compounds written by M.H. van Agteren and published by Springer Science & Business Media. This book was released on 1998-05-31 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of synthetic organic chemicals into the environment during the last few decades has given rise to major concern about the ecotoxicological effects and ultimate fate of these compounds. The pollutants that are considered to be most hazardous because of their intrinsic toxicity, high exposure level, or recalcitrant behavior in the environment have been placed on blacklists and other policy priority lists. The fate of synthetic compounds that enter the environment is mainly determined by their rate of biodegradation, which therefore also has a major effect on the degree of bioaccumulation and the risk of ecotoxicological effects. The degree and rate of biodegradation is also of critical importance for the feasibility of biological techniques to clean up contaminated sites and waste streams. The biodegradation of xenobiotics has thus been the subject of numerous studies, which resulted in thousands of publications in scientific journals, books, and conference proceedings. These studies led to a deeper understanding of the diversity of biodegradation processes. As a result, it has become possible to enhance the rate of degradation of recalcitrant pollutants during biological treatment and to design completely new treatment processes. At present, much work is being done to expand the range of pollutants to which biodegradation can be applied, and to make treatment techniques less expensive and better applicable for waste streams which are difficult to handle.

Download or read book Metabolism of Drugs and Other Xenobiotics written by Pavel Anzenbacher and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

Download or read book Xenobiotics in the Urban Water Cycle written by Despo Fatta-Kassinos and published by Springer Science & Business Media. This book was released on 2010-01-06 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of chemistry and pharmaceutical sciences is an impressive success story. The products of chemical and pharmaceutical industries are present eve- where in our everyday life. They help to pursue the modern way of living and they contribute to our high standard of living and safety, mobility, communication te- nologies, food, health, textiles and drinking water treatment, among many others. These products are labeled under the categories: pharmaceuticals, pesticides, det- gents, fertilizers, dyes, paints, preservatives, food additives and personal care pr- ucts, to name a few. Within these categories, groups of chemicals with similar structures can be found. However, often groups of chemicals with very different structures belong to the same category. For a long time the production of chemicals and pharmaceuticals, their usage and application was connected with the heavy pollution of the environment and serious health effects. At the end of the last century, it was realised that the products of che- cal and pharmaceutical industries are presenting a new type of environmental pol- tion that may also pose a health risk to the consumer. Most chemicals are used in so-called open applications in excessive amounts e. g. for personal care, hygiene, plant protection, health and in textiles. In many cases such as scents, detergents, textile chemicals, surface disinfectants, pesticides and others it is unavoidable that these chemicals are released into the environment according to their intended use.

Download or read book Advances in Biodegradation and Bioremediation of Industrial Waste written by Ram Chandra and published by CRC Press. This book was released on 2015-03-24 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses a Global Challenge to Sustainable DevelopmentAdvances in Biodegradation and Bioremediation of Industrial Waste examines and compiles the latest information on the industrial waste biodegradation process and provides a comprehensive review. Dedicated to reducing pollutants generated by agriculturally contaminated soil, and plastic waste fr

Download or read book Handbook of Metabolic Pathways of Xenobiotics written by Philip Lee and published by Wiley. This book was released on 2014-03-17 with total page 2560 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you’re working on or studying the effects of drug metabolisms, then this reference is for you! Handbook of Metabolic Pathways of Xenobiotics is an essential new reference which presents the metabolic fate of xenobiotics in animals and plants, and shows the metabolic pathways in the environment. Presenting a comprehensive guide to understanding the metabolisms of xenobiotics, the Handbook of Metabolic Pathways of Xenobiotics spans five volumes: Volumes 1-2 are Review Articles and Volumes 3-5 are Compound Articles. Review Articles present detailed reviews on the techniques and methods used to establish in vitro and in vivo metabolic pathways. Compound Articles are carefully selected lists of key chemicals representing agrochemicals, pharmaceuticals, animal health products and industrial chemicals. An essential addition to every library, this introduction, guide and catalogue presents: Current topics in the metabolism of xenobiotics Topics of both scientific and regulatory importance are covered, including in vitro high throughput metabolism screens, computer-aided metabolism predictions, and advances in bioanalytical techniques. Techniques and methods used in metabolic pathways 29 chapters provide an introduction to the understanding of drug metabolism and detail how to establish in vitro and in vivo metabolic pathways. Biotransformation pathways Presented as a catalogue of short articles covering major pharmaceuticals, agrochemicals, animal health products and industrial chemicals. Each article summarizes the chemical properties and uses, and presents a detailed review of the chemical and metabolic pathways in soil, plants and animals. Over 450 examples of xenobiotics and their fate in animals and plants Each compound includes systematic information about the metabolic pathway of drugs for human and veterinary medicine, agrochemicals and major industrial chemicals. Chemical and biological fate data The Handbook summarises data from scientific literature, patent literature, industrial resources and regulatory agencies, such as the EPA, FDA, EU, WHO and FAO, in a single reference for the first time. An essential reference for everyone working and studying pharmacokinetics and drug metabolism Coverage of the chemical and biological reactivity of molecules and primary sub-structures makes this an ideal reference for students and research scientists. The broad and diverse coverage of chemical and biological fate under different exposure and biological compartments make this a useful resource for regulatory and developmental scientists. Experience the scope of content offered in the Handbook of Metabolic Pathways of Xenobiotics for yourself, download these articles today: Review Article: Fundamentals of organic chemistry as applicable to the biotransformation of foreign compounds Review Article: Metabolic stability screen in drug discovery Review Article: Unusual metabolic reactions and pathways Compound Article: Ganoderic acid D Compound Article: Milnacipran Compound Article: Tenofovir Online Edition Coming Soon! Featuring the same great content as the five volume print set, the Handbook of Metabolic Pathways for Xenobiotics will be available on Wiley Online Library in summer 2014. The online reference will benefit from the enhanced functionality powered by The Smart Article – learn more about The Smart Article at wileyonlinelibrary.com/thesmartarticle. Free trials will be available when the Online Edition goes live, bookmark this page or sign-up for regular product alerts at www.wiley.com/email to stay informed.