Download or read book The Enigma of Slow Viruses written by Pawel P. Liberski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scrapie, a naturally occurring neurodegenerative disease of sheep and sometimes goats, is a prototypic disease for the whole group of the subacute spongiform virus encephalopathies. Kuru was the first human disease of this type to be discovered in 1957 by Gajdusek and Zigas, and its discovery opened the whole field in the human biomedical sciences by the very realization of the fact that viruses may induce disease months or even decades after infections, and that these slow virus diseases are more compatible with classical degenerations of the nervous system than with inflammatory disorders of the brain. More than a quarter of a century since discovery of Kuru, and more than half a century following the first transmission of scrapie, the very nature of the infectious virus remains unknown. This comprehensive review covers all aspects of slow unconventional virus infections known today. It includes numerous historical data, biochemistry and molecular biology of the prion protein and its gene, the role of genetics and mutations within PrP gene, spreading and targeting of the virus, biochemistry and neurochemistry of the alterations of different neurotransmitter system and neuropathology. More than 1000 references are listed and critically analyzed; the reader can find references to all experiments and laboratory findings which has ever been done in this field. Furthermore, the book offers different view on the basic problems as for example, the nature of the scrapie agent.
Download or read book The Enigma of Slow Viruses written by P. P. Liberski and published by Springer Verlag. This book was released on 1993-01-01 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Persistent Viral Infections written by R. Ahmed and published by Wiley-Blackwell. This book was released on 1999 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.
Download or read book Unconventional Agents and Unclassified Viruses written by O.-R. Kaaden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among unconventional agents and unclassified viruses the contributions to this volume focused on prion-related diseases, with special emphasis on bovine spongiform encephalopathy and human spongiform encephalopathies, and Borna disease virus, an agent known since long time to be pathogenic for horses and sheep, which is now discussed as a potential pathogen for humans. Additionally, the volume contains articles about newly discovered viruses like porcine respiratory and reproductive syndrome virus and viruses that are classified only provisionally like African swine fever virus, hepatitis C and E viruses, or the arteriviruses.
Download or read book The Threat of Pandemic Influenza written by Institute of Medicine and published by National Academies Press. This book was released on 2005-04-09 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.
Download or read book Imported Virus Infections written by Tino F. Schwarz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals both with the epidemiologic background and the specific characteristics of vector-borne and emerging viral infections which may be spread all over the world due to today’s rapid transport of infected individuals or animal vectors. Detailed description of the situation with e.g. Dengue, Japanese encephalitis, Lassa, hepatitis, HIV and filoviruses helps to plan diagnostic approaches and to develop scenarios for the handling of patients suspected of carrying high hazard viruses.
Download or read book Positive Strand RNA Viruses written by Margo A. Brinton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positive-strand RNA viruses include the majority of the plant viruses, a number of insect viruses, and animal viruses, such as coronaviruses, togaviruses, flaviviruses, poliovirus, hepatitis C, and rhinoviruses. Works from more than 50 leading laboratories represent latest research on strategies for the control of virus diseases: molecular aspects of pathogenesis and virulence; genome replication and transcription; RNA recombination; RNA-protein interactions and host-virus interactions; protein expression and virion maturation; RNA replication; virus receptors; and virus structure and assembly. Highlights include analysis of the picornavirus IRES element, evidence for long term persistence of viral RNA in host cells, acquisition of new genes from the host and other viruses via copy-choice recombination, identification of molecular targets and use of structural and molecular biological studies for development of novel antiviral agents.
Download or read book Virus Mania written by Torsten Engelbrecht and published by BoD – Books on Demand. This book was released on 2021-04-22 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book 'Virus Mania' has been written with the care of a master-craftsman, courageously evaluating the medical establishment, the corporate elites and the powerful government funding institutions." Wolfgang Weuffen, MD, Professor of Microbiology and Infectious Epidemiology "The book 'Virus-Wahn' can be called the first work in which the errors, frauds and general misinformations being spread by official bodies about doubtful or non-virus infections are completely exposed." Gordon T. Stewart, MD, professor of public health and former WHO advisor - - - The population is terrified by reports of so-called COVID-19, measles, swine flu, SARS, BSE, AIDS or polio. However, the authors of "Virus Mania," investigative journalist Torsten Engelbrecht, Dr. Claus Köhnlein, MD, Dr. Samantha Bailey, MD, and Dr. Stefano Scoglio, BSc PhD, show that this fearmongering is unfounded and that virus mayhem ignores basic scientific facts: The existence, the pathogenicity and the deadly effects of these agents have never been proven. The book "Virus Mania" will also outline how modern medicine uses dubious indirect lab tools claiming to prove the existence of viruses such as antibody tests and the polymerase chain reaction (PCR). The alleged viruses may be, in fact, also be seen as particles produced by the cells themselves as a consequence of certain stress factors such as drugs. These particles are then "picked up" by antibody and PCR tests and mistakenly interpreted as epidemic-causing viruses. The authors analyze all real causes of the illnesses named COVID-19, avian flu, AIDS or Spanish flu, among them pharmaceuticals, lifestyle drugs, pesticides, heavy metals, pollution, malnutrition and stress. To substantiate it, the authors cite dozens of highly renowned scientists, among them the Nobel laureates Kary Mullis, Barbara McClintock, Walter Gilbert and Sir Frank Macfarlane Burnet as well as microbiologist and Pulitzer Prize winner René Dubos, and it presents more than 1,400 solid scientific references. The topic of "Virus Mania" is of pivotal significance. Drug makers and top scientists rake in enormous sums of money and the media boosts its audience ratings and circulations with sensationalized reporting (the coverage of the "New York Times" and "Der Spiegel" are specifically analyzed).The enlightenment about the real causes and true necessities for prevention and cure of illnesses is falling by the wayside. For more reviews, see the older edition of "Virus Mania"
Download or read book Infectious AIDS written by Peter Duesberg and published by North Atlantic Books. This book was released on 1995 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of 13 articles originally published in scientific journals between 1987 and 1995, that call into question the dogma of Infectious AIDS.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1991 with total page 1460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Trends in the Diagnosis and Therapy of Alzheimer s Disease written by Kurt A. Jellinger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer ́s Disease (AD), the most frequent cause of mental decline in the elderly represents one of the major health problems facing modern society. Despite considerable progress in the clinical diagnosis, epidemiology, structural basis, biochemistry, molecular genetics, and pharmacological aspects of AD, its etiology, molecular backgrounds, and treatment challenges are still poorly understood. This volume based on the 2nd International Symposium of EBEWE Research Initiative in October 1993 in Salzburg, Austria, is conceived as a review of our current knowledge of morphology, diagnostic clinical and imaging techniques, methodological approaches of cognitive assessment, trial designs, outcome variables and possibilities of therapy of AD and other neurodegenerative disorders. The book ́s coverage is broad and it should be of interest for investigators, clinicians, and researchers involved in the problems of AD.
Download or read book Zombie CSU written by Jonathan Maberry and published by Citadel Press. This book was released on 2010-04-19 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: When there's no more room in hell, the dead will walk the earth. . . And law enforcement is ready to take them down! Since Night of the Living Dead, zombies have been a frightening fixture on the pop culture landscape, lumbering after hapless humans, slurping up brains and veins and whatever warm, fleshy matter they can clench in their rotting limbs. But what if they were real? What would happen if, tomorrow, corpses across the nation began springing up out of their graves and terrorizing the living? Employing hard science and solid police work--not to mention jaw-dropping (literally!) humor--Zombie CSU is the only guide you need to make it through alive--not undead. At last you can: • Investigate zombie crime scenes, collecting and analyzing evidence of zombie attacks, and create a "murder book." • Examine the psychology of the zombie and develop a perp profile. • Observe medical science pros as they probe felled zombies for forensic clues. • Devise a zombie apocalypse survival scorecard and more! Complete with lists of must-see zombie flicks from around the globe and tons of tips for kicking undead butt, Zombie CSU features hundreds of interviews with real zombie experts, forensics experts, detectives, filmmakers, and more. Special guest stars: Tony Todd, Brian Keene, Patricia Tallman, David Wellington, James Gunn, Robert Kirkman, Dr. Wade Davis, Robert Sacchetto, Zombie Squad, Ramsey Campbell, Kim Paffenroth, Jamie Russell, Michael "CJ" Kelly, Bruce "Andy" Bohne, and dozens more! "Fascinating! An indispensable tool for anyone contemplating tackling a festering corpse onslaught." -- Fearzone.com "Candid, eye-opening, cutting-edge, startling . . . the existence of zombies may not be so far-fetched after all." --Rue Morgue
Download or read book Chronic Infectious Neuropathic Agents CHINA and other Slow Virus Infections written by Jacob A. Brody and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Laboratory Diagnosis of Infectious Diseases Principles and Practice written by Edwin H. Lennette and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 983 pages. Available in PDF, EPUB and Kindle. Book excerpt: those who deal with infectious diseases on a daily This two volume work stems from the belief of the Editors that infectious diseases are not only very basis. much with us today but, more importantly, that they There are several excellent textbooks dealing will continue to playa significant global role in mor with medical microbiology, and there are equally bidity and mortality in all people. A continuing need well-recognized books devoted to infectious dis for an informed and knowledgeable community of eases. The Editors of this work, on the other hand, were persuaded that there was a need for a publica laboratory scientists is fundamental. Data describing tion that would bring together the most pertinent and the global impact of infectious diseases are difficult to come by. Fortunately, a recent thoughtful and relevant information on the principles and practice of provocative publication by Bennett et al. (1987) pro the laboratory diagnosis of infectious diseases and vides us with data derived from several consultants include clinical relationships. While this two volume that clearly delineate the impact of infectious dis text is directed toward the role of the laboratory in eases on the United States today.
Download or read book Flu written by Gina Kolata and published by Farrar, Straus and Giroux. This book was released on 2011-04-01 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.
Download or read book Oncogenes Aneuploidy and AIDS written by Harvey Bialy and published by North Atlantic Books. This book was released on 2004 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to author Harvey Bialy, the work of molecular biologist Peter Duesberg has been grossly distorted by the media and scientific establishments. Until recently, the scientific community--and most notably, those from the National Institute for Health--have been unwilling to look at his provocative theories of different causes for cancer and HIV/AIDS. Inspired by UC Berkeley's rare creation of an archive for Duesberg's papers, this book explores Duesberg's early groundbreaking work with viruses and oncogenes, his contentious fights with other scientists, and the profound influence of his life's work.
Download or read book Infectious Diseases of the Central Nervous System written by R.A. Thompson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this volume are based upon the proceedings of a Sympo sium entitled "Infectious Diseases of the Central Nervous System" held in Phoenix, Arizona, and sponsored by the Barrow Neurological Institute and Foundation during its Ninth Annual Symposium. The purpose of the Symposium was to bring together knowledgeable experts in this field to review information that is available and to enhance our knowledge of new developments in the field of infectious diseases in the central nervous system. Because the subject could not be covered in its entirety by this volume, we have placed particular emphasis on recent developments and new information. The volume includes a remarkably fresh and interesting discussion of viral diseases as they affect the nervous system, including conventional and unconventional virus agents, and in addition, discussions of path ophysiology and epidemiology and postinfectious diseases of the nervous system. A similar approach is taken to the treatment of bacterial infection. Discussions of pathophysiology are intertwined with discussions of diag nostic techniques, prevention techniques and treatment of bacterial in fections. Additional surgical problems are discussed regarding prevention and management of peri operative infection and brain abscess. Special consid eration was given to coccidioidomycosis which is prevalent in the western states; also, there is a discussion of parasitic infections. This volume will be of interest to neurologists and neurosurgeons and any physician dealing with infectious disease. RICHARD A. THOMPSON, M.D. JOHN R. GREEN, M.D.
