Download or read book The Effects of Fusarium Mycotoxins on the Intestinal Epithelial Cell Mediated Defense Response written by Lam-Yim Wan and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "The Effects of Fusarium Mycotoxins on the Intestinal Epithelial Cell-mediated Defense Response" by Lam-yim, Wan, 尹琳艷, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4715144 Subjects: Fusarium - Toxicology Mycotoxins Intestines - Infections Epithelial cells
Download or read book The Effects of Fusarium Mycotoxins on the Intestinal Epithelial Cell mediated Defense Response written by Lam-yim Wan and published by . This book was released on 2011 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Damp Indoor Spaces and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-10-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.
Download or read book Fusarium written by Tulin Askun and published by BoD – Books on Demand. This book was released on 2018-07-25 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fusarium species are ubiquitous environmental fungi and can cause severe invasive infections in plants. They are crop pathogens, and consumption of such infected crops can cause diseases in humans and animals. Furthermore, they act as spoilage organisms in stored products, such as wheat, sorghum, rice, and corn (maize). Fusarium species are mycotoxin producers and contaminate food and grains. Therefore, their eradication and management have economic importance as they can cause enormous economic and agricultural production losses. Despite the fact that the genus Fusarium Link (1809) has been known for over 200 years, new scientific information is being revealed by rapid advancements and breakthrough findings of interdisciplinary studies. This book presents an introductory overview of an update to the scientific knowledge about Fusarium. It discusses various aspects of Fusarium, such as its genetic diversity, root rot incidence and severity, genetic resistance, molecular markers, mycotoxins, diseases caused by Fusarium, and their management and the biological control of these phytopathogens. Furthermore, it also elaborates upon new plant secondary metabolites that are effective against Fusarium and the molecular interaction between Fusarium and the plant.
Download or read book Recent Advances and Perspectives in Deoxynivalenol Research written by Marc Maresca and published by MDPI. This book was released on 2018-07-09 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi--mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)--the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12-13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant-fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues. Dr. Marc Maresca Guest Editor
Download or read book Ergot written by Vladimir Kren and published by CRC Press. This book was released on 1999-04-08 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with biotechnological aspects of ergot alkaloid production and genetic and physiological data. Toxicology and environmental risks of ergot infection and contamination of food and forage are also detailed
Download or read book The Mycotoxin Blue Book written by Duarte Diaz and published by Context Products. This book was released on 2005-01-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moulds and the mycotoxins they produce, have a wide-ranging economic impact on animal agriculture on every continent of the globe. Mould growth robs feed nutritive value and reduces intake, which lowers efficiency. Mycotoxins, even when present at levels previously considered 'trace', have negative effects on performance and health, particularly in the context of today's more highly productive modern livestock genetics. Food-borne toxins also threaten human health through contaminated cereal and protein sources and transfer of toxins in food animal products. The Mycotoxin Blue Book focuses on the physiological effects and field occurrence of mycotoxins. Detailed information on types of moulds and mycotoxins and the conditions under which moulds flourish is included. Implications of mycotoxin contamination of feedstuffs for all major food animal species are presented in addition to aquaculture and companion animals. Sampling and analytical issues are covered in depth; as is the topic of mycotoxins in human foods. Finally, practical means of ameliorating mycotoxin effects are addressed. It is the hope of the editor and authors that the material herein will lead to clearer recognition of mycotoxin problems and ultimately to ways of reducing their impact on food animal production. An excellent guide for nutritionists, advisors, farmers and students involved with and using animal feed. Contents: Sampling feeds for mycotoxin analysis Mycotoxins: their effects in poultry and some practical solutions Effects of mycotoxins in horses Effects of mycotoxins on domestic pet species Effects of mycotoxins on antioxidant status and immunity Mycotoxins in aquaculture Principles and applications of mycotoxin analysis Mycotoxins in the human food chain Mould growth and mycotoxin production Current concepts in mycotoxicoses in swine Mycotoxins in forages Mycotoxin interactions Mycotoxins: metabolism, mechanisms and biochemical markers Effects of mycotoxins in ruminants Mycotoxin sequestering agents: practical tools for the neutralisation of mycotoxins Index
Download or read book The Effects of Mycotoxins on Human and Animal Health a Special Focus on the Cellular and Molecular Mechanisms Responsible for Mycotoxin Toxicity written by Daniela Eliza Marin and published by Mdpi AG. This book was released on 2022-01-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue gathers original studies (eight articles and one review) that aim to improve our knowledge concerning mycotoxin toxicity. The most recent research concerning the impact of zearalenone (ZEA) and the immune response is presented in a review that aims to explore the immunotoxicity produced by ZEA on different types of immune cells (phagocytes related to innate immunity and lymphocytes related to acquired immunity) as well as on immune organs, and also to identify the mechanism of action used by ZEA to modulate the immune response. The role of zearalenone in macrophage-mediated innate immunity after bacterial lipopolysaccharide (LPS) stimulation was the subject of another study, suggesting that the intake of ZEA-contaminated food might result in decreasing innate immunity. Another important study related to the co-exposure to mycotoxins and other food/feed contaminants showed that combining patulin with cadmium induces enhanced hepatotoxicity and nephrotoxicity both in vitro and in vivo, while the exposure to both deoxynivalenol and porcine circovirus has an additive effect on inflammatory cytokines by inducing the mRNA expression of interleukine-1 beta (IL-1β) and interleukine-6 (IL-6). The use of feed compounds rich in bioactive constituents for mitigating the mycotoxins effects in swine was the subject of other three studies herein, which have shown the efficacy of antioxidants from dietary grapeseed and sea buckthorn meal waste to decrease the toxicity of a diet contaminated with aflatoxin B1 or both aflatoxin B1 and ochratoxin A at the level of organs involved in the metabolism and excretion (liver and kidney), as well as at the level of secondary lymphoid organs (mesenteric lymph nodes). The use of different models (cell co-culture model, rat model) are recommended by another two studies in order to evaluate the ochratoxin A toxicity or for better prediction of the mycotoxins risk for human cancer.
Download or read book Fungal Diseases in Animals written by Arti Gupta and published by Springer Nature. This book was released on 2021-06-22 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of fungal infections in both human and animals has increased over the last few decades. This book presents an overview of the different categories of fungal infections that can be encountered in animals (including lower vertebrates) originating from environmental sources with or without transmission to humans. In addition, the endemic infections with indirect transmission from the environment, the zoophilic fungal pathogens with near-direct transmission, the zoonotic fungi that can be directly transmitted from animals to humans, mycotoxicoses and antifungal resistance in animals will also be discussed. This book includes case studies and reviews the current state of knowledge on the mechanism of fungal attraction, recognition, infection, extracellular hydrolytic enzymes and pathogenesis of nematophagous fungi. The book also covers diagnostics, fungal formulations, as well as prevention methods. It discusses strategies to access the fungal pathogen groups, metagenomic analyses, genomics, secretomics, metabolomics, proteomics and transcriptomics. In addition, pathogen description, understanding, distribution and recent research results are provided.
Download or read book Masked Mycotoxins in Food written by Chiara Dall'Asta and published by Royal Society of Chemistry. This book was released on 2015-11-05 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products. Mycotoxins are naturally occurring chemicals produced by moulds that can grow on crops and foodstuffs. Masked mycotoxins are modified mycotoxins, due to this modification many cannot be detected using standard analytical techniques, for example HPLC and ELISA, and further research is needed to understand the health risks and threats from these modified compounds.Masked mycotoxin research is an area of toxicological research that has gained significant interest and momentum in recent years. The aim of this book is to provide a full picture of the topic, from the masked mycotoxin formation in plants to their catabolic fate in humans. The book also provides new insights and will highlight possible gaps in the knowledge base of this relatively new area. Edited and written by World renowned experts working within the field, this book is of interest to toxicologists and biochemists, but also food scientists and agricultural researchers working in industry and academia.
Download or read book Handbook of Secondary Fungal Metabolites written by Richard J. Cole and published by Gulf Professional Publishing. This book was released on 2003 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set is a desirable reference for a wide range of specialists who study secondary fungal metabolites ranging from pharmaceutical house researchers, agricultural researchers, those involved in food and feed control regulation, and veterinary researchers. It discusses in depth the molecular formula of, the molecular weights of, and fungal/plant source indexes of secondary fungal metabolites.
Download or read book Field Manual of Wildlife Diseases written by and published by Geological Survey (USGS). This book was released on 1999 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of Food and Water Borne Mycotoxigenic and Mycotic Fungi written by R. Russell M. Paterson and published by CRC Press. This book was released on 2015-06-24 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: A part of the Food Microbiology Series, Molecular Biology of Food and Water Borne Mycotoxigenic and Mycotic Fungi reveals similarities between fungi present in/on food and water and those that cause human fungal diseases. The book covers food borne mycotoxigenic fungi in depth and examines food borne fungi from the standpoint of mycoses (i.e. funga
Download or read book Mycotoxins Occurence in Feed and Their Influence on Animal Health written by Maciej Gajęcki and published by MDPI. This book was released on 2021-01-15 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the presented studies, the health condition of animals in rearing and breeding should be regularly monitored. This would allow early detection of delicate deviations in the body of clinically healthy individuals. Unfortunately, regular monitoring of the health of animals in commercial production is not performed. It follows that this type of research should be an introduction to further, more inquisitive steps. This can form the basis for further courses of action, indicating which organs or tissues field doctors or researchers should be interested in and what to pay attention to in order to find the correct answer, concerning the situation in the animal body. In the future, we should determine biomedical markers for use in precision veterinary medicine. In human medicine, this has been practiced with great success. The problem, however, is that we are getting to know more and more substances produced by mold fungi. This causes a build-up of new interpretative problems, causing health conditions (diagnosis), as well as analytical problems. To fully understand the results we need new techniques to assess toxicological and chemical hazards, including those related to undesirable substances. We need a solid knowledge of the biological pathways underlying the toxicity and tolerance to interference factors toxicological processes. We hope that the presented study will allow for a better understanding of mycotoxicoses that bother us and our animals, which will allow for more effective preventive actions.
Download or read book Food Safety and Toxicity written by John De Vries and published by CRC Press. This book was released on 2021-10-08 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Safety and Toxicity examines the many problems and changes in food safety and toxicity. From a natural science viewpoint, this informative book takes on challenging and important topics impacting food researchers, regulators, producers, healthcare providers, educators, and consumers. It is organized into three main sections. Section 1 explores the relationship between the origin or formation of potentially toxic compounds and their eventual ingestion. Section 2 picks up with information on the potential consequences of this ingestion, and Section 3 concludes with the discussion of prevention and minimization of health risks. By emphasizing food safety, rather than nutritional toxicology, this book puts food hazards and their health risks in true perspective. It also explores the complementary roles of toxicology and epidemiology in studying associations between nutrition and adverse health effects and in assessing toxicological risks from food components in a deliberate manner. Food Safety and Toxicity, with clear, non-technical language and valuable insight, brings you up-to-date on the significant food safety issues confronting us today.
Download or read book Identifying and Controlling Immunotoxic Substances written by and published by Office of Technology Assessment. This book was released on 1991 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Probiotic in Animals written by Everlon Rigobelo and published by BoD – Books on Demand. This book was released on 2012-10-03 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few decades the prevalence of studies about probiotics strains has dramatically grown in most regions of the world. The use of probiotics strains in animals production may reduce several problems caused by antibiotics therapy, growth promoter and problems from inadequate management. Probiotics are specific strains of microorganisms, which when served to human or animals in proper amount, have a beneficial effect, improving health or reducing risk of get sick. This book provides the maximum of information for all that need them trying with this to help many people at worldwide.