Download or read book The Development of Miniature Centrifugal and Axial flow Pumps for Use as Cardiac assist Devices written by Elizabeth Ann L'Estrange and published by . This book was released on 1987 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Centrifugal and Axial Flow Pumps written by Alexey Joakim Stepanoff and published by Keieger Publishing Company. This book was released on 1993 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mechanical Circulatory Support Principles and Applications written by David L. Joyce and published by McGraw Hill Professional. This book was released on 2011-10-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: An all-in-one guide to mechanical assist devices for the treatment of heart failure This complete guide addresses all of the clinical scenarios encountered by the health care team during the pre-operative, intra-operative, and post-operative periods following device implantation. In addition, it outlines the specific attributes of various technologies that are currently utilized by clinicians, giving you a practical view of how the latest devices work. You’ll also find a mini-catalog of the spectrum of current devices, complete with their technical and clinical specifications. Drawing on the latest published data and the combined global expertise of a renowned author team, Mechanical Circulatory Support puts the field’s most essential perspectives right at your fingertips. FEATURES: The unmatched mechanical circulatory device sourcebook, covering the physiological, technical, regulatory, and clinical aspects of ventricular assist devices Full-color presentation features a wide range of photographs, radiographs, tables, and clearly labeled clinical and schematic illustrations Essential insights into the physiology of heart failure, which provides a basic foundation of knowledge for understanding the role of mechanical circulatory assistance in the management of heart failure Logical two-part organization consisting of: Clinical Considerations in mechanical circulatory support, including device history/development and indications for device therapy; perioperative management; complications; and special considerations (use in infants/children, pulmonary hypertension during LVAD support, and more) Device-Specific Considerations, which provides a mini-catalog of manufacturer’s devices—-from short-term devices to long-term continuous flow devices—-and highlights technical and clinical specifications for each product Guide to appropriate device selection using a simplified framework in an industry that produces an increasing array of short- and long-term therapies Helpful chapter introductions provide essential background information that places each chapter topic in its proper clinical and technical context Conclusions at the end of each chapter offer a concise summary of chapter material Full chapter-ending references provide opportunities for further research

Download or read book Mechanical Circulatory Support A Companion to Braunwald s Heart Disease Ebook written by James K. Kirklin and published by Elsevier Health Sciences. This book was released on 2019-07-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering comprehensive, authoritative coverage of mechanical circulatory support (MCS), this fully revised companion to Braunwald’s Heart Disease provides the clinically relevant information you need to effectively use this therapy to treat and manage end-stage heart failure. New editors and authors – experts in both cardiology and cardiovascular surgery – bring you fully up to date with the newest technology and devices, as well as basic science, clinical applications, adverse event monitoring and management, socioeconomic implications, future directions, and more. Covers all of the newest techniques, including new-generation devices. Discusses the management of common patient problems, highlighting cautions and outcomes, as well as pathophysiology and rationale for treatment. Brings you up to speed with the latest coverage of ventricular assist devices (VAD), extracorporeal membrane oxygenation (ECMO), next-generation centrifugal pumps, and total artificial hearts. Provides a complete clinical perspective of the latest scientific breakthroughs and analysis of the current literature. Includes coverage of the most recent guidelines and protocols, including MCS for pediatric and congenital heart disease; the Interagency Registry of Mechanically Assisted Circulatory Support (INTERMACS) as a tool to track and advance clinical practice; and cellular, molecular, genomic, and functional changes that occur in the failing heart in response to MCS. Presents practical evidence from the registry of thousands of cases to guide cardiologists, cardiovascular surgeons, emergency physicians, primary care physicians, and other team members on the best management course to follow for each particular patient.

Download or read book Rotary Blood Pumps written by Hikaru Matsuda and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rotary blood pumps increasingly are being used in open heart surgery and in assisted circulation for patients with heart disease. These rotary devices include vortex (centrifugal) and axial pumps, which can be utilized in conditions where the use of conventional pulsatile pumps would entail problems of cost and size. Rapid progress is now being made in developing new devices for controlling blood flow within the heart and great vessels as well as extracorporeally for use in coronary and intensive care units and, in the future, for long-term use. This book provides information on the physiology of nonpulsatile circulation, the development of rotary pump engineering, and the clinical application of rotary blood pumps. It also presents an overview of future developments in this important field.

Download or read book Biomedical Devices and Their Applications written by D. Shi and published by Springer Science & Business Media. This book was released on 2004-10-05 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces readers to the basic concepts and recent advances in the field of biomedical devices. The text gives a detailed account of novel developments in drug delivery, protein electrophoresis, estrogen mimicking methods and medical devices. It also provides the necessary theoretical background as well as describing a wide range of practical applications. The level and style make this book accessible not only to scientific and medical researchers but also to graduate students.

Download or read book Core Topics in Cardiothoracic Critical Care written by Kamen Valchanov and published by Cambridge University Press. This book was released on 2018-07-05 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most patients with critical cardiac or thoracic conditions will at some stage pass through the cardiothoracic critical care unit. Critical care presents more complex clinical data than any other area of medicine. The new edition of Core Topics in Cardiothoracic Critical Care focuses on the latest practise in the management of patients in cardiothoracic intensive care. The practice of cardiothoracic critical care medicine is constantly evolving, and this new edition reflects the modernized learning styles for trainees. Each chapter includes key learning points as well as sample multiple choice questions and answers to assist in exam preparation. This edition also features updated chapters on ECMO, perioperative management of patients undergoing emergency cardiothoracic surgery, and advanced modes of organ support for patients. This text provides key knowledge in a concise and accessible manner for trainees, clinicians and consultants from specialities and disciplines such as cardiology and anaesthesia, and nursing and physiotherapy.

Download or read book New Continuous Flow Total Artificial Heart For Use in Smaller Sized Adults and Pediatric Patients written by Carson Solon Fox and published by . This book was released on 2019 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congestive heart failure (CHF) is a progressive and debilitating disease that affects millions of adults and children worldwide. Hundreds of thousands of new cases of CHF are diagnosed each year in the U.S., and this high volume of patients costs the healthcare industry tens of billions annually. The inadequate number of donor hearts and limited long-term effectiveness of pharmacologic treatment necessitate the development and use of mechanical circulatory support (MCS) therapies. Clinical utilization of MCS devices has demonstrated that patients derive substantial survival and quality of life benefits from shortand long-term MCS. Only two total artificial hearts (TAHs) are approved for implantation in the U.S., and the implementation of TAHs in the treatment of patients with CHF has increased more than 3 fold in the last 6 years. To address the limitations of current technology and to provide a new and novel therapeutic alternative, we are developing an innovative, hybrid-design, continuous flow, implantable, magnetically levitated TAH (Dragon Heart). The Dragon Heart is designed to provide cardiovascular support to pediatric and adult patients. This compact medical device has a target diameter and height of 70 mm by 50 mm, respectively; it is designed to generate the physiologic pressures and flows necessary to support CHF patients. This TAH has only 2 moving parts: an axial flow impeller to drive blood flow through the pulmonary circulation and a centrifugal flow impeller to drive blood flow through the systemic circulation. This device utilizes the latest generation of magnetic bearing technology to levitate the impellers, thus enabling an operational lifespan of 15 years. The design incorporates wider clearances between the rotating impellers and pump housing. Larger clearances lead to lower fluid shear stresses, hence mitigating the risk of thrombosis and hemolysis. This design avoids the use of mechanical or biologic valves and has an antithrombogenic coating applied to blood-contacting surfaces, thus further reducing the risk of thrombosis. It integrates state-of-the-art monitoring with Wifi-based sensors to report operational status and produces both continuous and pulsatile blood flow. A transcutaneous energy transfer system using wireless technology will be incorporated to supply power to the device and to eliminate the percutaneous driveline that protrudes from the abdomen, which is a major source of infection for patients who are supported by current MCS technology. This dissertation research concentrated on advancing the development of the axial and centrifugal blood pumps that constitute the core components of the Dragon Heart. Three substantial design phases were completed. The pump geometries (axial and centrifugal) were established using advanced pump design equations, 3D modeling and pump design software, and available literature on blood pumps. ANSYS computational fluid dynamic software was used to evaluate the pressure-flow generation, irregular blood flow velocities and patterns, estimated power consumption, radial and axial fluid forces on the rotor, fluid stress levels, blood cell residence time in the device, and blood damage predictions. The computational models served as the foundation by which prototype manufacturing was completed for hydraulic testing. Three hydraulic test rigs were constructed to test the pressure generation and levels of hemolysis in the prototypes. A blood analog solution of water and glycerin was utilized for the hydraulic experiments, and bovine blood was used for the repeated hemolytic studies. During the design process, the axial and centrifugal pump designs were improved iteratively to reduce the size of the pumps without compromising pump performance. This process resulted in a small device size of 57 mm by 50 mm, surpassing the target goal. The simulations revealed that both pumps were able to generate adequate pressure and blood flow to support adult and pediatric patients. Computational results followed expected theoretically trends for pumps in general. Radial and axial fluid forces were estimated to be less than 0.4 N and 3 N, respectively. Maximum fluid stress levels remained less than 320 Pascal with maximum exposure times of less than .54 seconds. Blood damage models for several operating conditions indicated low damage levels of less than 2%. Estimated power consumption was determined to be less than 6 Watts. Physical prototypes of the axial and centrifugal pump designs were manufactured for hydraulic and hemolytic testing. The experiments demonstrated that the Dragon Heart is capable of delivering the target blood flows of 1-5 LPM and pressure rises of greater than 15 mmHg for the pulmonary circulation and greater than 95 mmHg for the systemic circulation for acceptable rotational speeds. The centrifugal prototypes had a general trend of outperforming the computational predictions by 37.5%; while the axial flow prototypes showed a decreased pressure-flow range during testing as compared to the computational studies. The data trends of the hemolytic studies followed expectations with a linear increase in plasma-free hemoglobin levels, slow decrease in hematocrit, and a consistent maintenance of operational conditions of the pump during the experiments. The Normalized Index of Hemolysis levels, however, were higher than anticipated in comparison to clinically used MCS devices. This is likely due to the materials of construction of the prototypes and surface roughness factors, which will be addressed in future work. This research and development effort is significant progress in the design of the Dragon Heart and represents a strong foundation by which to begin further optimization and development. The long-term goal of this research is to commercialize a novel, less expensive, more compact, low thrombus, and effective therapeutic alternative for adult and pediatric patients with CHF, thereby saving thousands of lives annually.

Download or read book The Artificial Heart written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program-and in particular, the National Institutes of Health's major investment-raising important questions. The volume includes: Consideration of the artificial heart versus heart transplantation and other approaches to treating end-stage heart disease, keeping in mind the different outcomes and costs of these treatments. A look at human issues, including the number of people who may require the artificial heart, patient quality of life, and other ethical and societal questions. Examination of how this technology's use can be targeted most appropriately. Attention to achieving access to this technology for all those who can benefit from it. The committee also offers three mechanisms to aid in allocating research and development funds.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 13th International Conference on Biomedical Engineering written by Chwee Teck Lim and published by Springer Science & Business Media. This book was released on 2009-03-15 with total page 2355 pages. Available in PDF, EPUB and Kindle. Book excerpt: th On behalf of the organizing committee of the 13 International Conference on Biomedical Engineering, I extend our w- mest welcome to you. This series of conference began in 1983 and is jointly organized by the YLL School of Medicine and Faculty of Engineering of the National University of Singapore and the Biomedical Engineering Society (Singapore). First of all, I want to thank Mr Lim Chuan Poh, Chairman A*STAR who kindly agreed to be our Guest of Honour to give th the Opening Address amidst his busy schedule. I am delighted to report that the 13 ICBME has more than 600 participants from 40 countries. We have received very high quality papers and inevitably we had to turndown some papers. We have invited very prominent speakers and each one is an authority in their field of expertise. I am grateful to each one of them for setting aside their valuable time to participate in this conference. For the first time, the Biomedical Engineering Society (USA) will be sponsoring two symposia, ie “Drug Delivery S- tems” and “Systems Biology and Computational Bioengineering”. I am thankful to Prof Tom Skalak for his leadership in this initiative. I would also like to acknowledge the contribution of Prof Takami Yamaguchi for organizing the NUS-Tohoku’s Global COE workshop within this conference. Thanks also to Prof Fritz Bodem for organizing the symposium, “Space Flight Bioengineering”. This year’s conference proceedings will be published by Springer as an IFMBE Proceedings Series.

Download or read book Mechanical Support for Heart Failure written by Jamshid H. Karimov and published by Springer Nature. This book was released on 2020-09-04 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of mechanical circulatory support of the failing heart in adults and children. The book uniquely combines engineering knowledge and the clinician’s perspective into a single resource, while also providing insights into current and future development of mechanical circulatory support technology, such as ventricular assist devices, the total artificial heart and catheter-based technologies for heart failure. Topics featured in this book include: The history of mechanical circulatory device development. Fundamentals of hemodynamics support. Clinical management of mechanical circulatory devices. Surgical implantation techniques. Current limitations of device therapies in advanced heart failure. Advanced and novel devices in the development pipeline. Opportunities for advancement in the field. Mechanical Support for Heart Failure: Current Solutions and New Technologies is a must-have resource for not only physicians, residents, fellows, and medical students in cardiology and cardiac surgery, but also clinical and basic researchers in biomedical engineering with an interest in mechanical circulatory support, heart failure, and new technological applications in medicine.

Download or read book The Transplantation and Replacement of Thoracic Organs written by D.K. Cooper and published by Springer Science & Business Media. This book was released on 2007-08-20 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a great pleasure for me to contribute a few words as an achieved by many heart transplant centers and the ever improving results of lung transplantation and the functioning of mechanical introduction to the second edition of this volume, first published in 1990 when it was edited by David Cooper and Dimitri cardiac assist devices. Novitzky. The first edition was, in fact, a greatly expanded The current editors bring a wealth of expertise and experience version of an even earlier volume Heart Transplantation, edited to their task, and have blended together absolutely superb con by David Cooper and Robert Lanza and published in 1984. This tributions by many of the world's experts in their fields. This first work, authored by members of the medical staff of Groote comprehensive and highly readable volume documents the Schuur Hospital and the University of Cape Town Medical present 'state of the art' in the field of transplantation and School, was, I believe, the first volume reviewing this relatively replacement of thoracic organs. It provides an invaluable and un new field of medicine. paralleled source of information for those concerned with heart and lung medicine or surgery, and is essential reading for all who The present volume, therefore, continues the documentation of wish to keep abreast of developments in this field.

Download or read book Mechanical Circulatory Support written by David L. Joyce and published by Oxford University Press, USA. This book was released on 2020-01-03 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanical Circulatory Support: Principles and Applications offers innovative approaches to complex clinical scenarios and represents the current state-of-the-art for managing patients on mechanical circulatory support devices. Topics are presented in a concise fashion, making it a practical resource for care givers who need a user's manual in the heat of the moment during patient care as well as a reference for a better understanding of the unique components of every device available for human use. This book provides a comprehensive, up-to-date analysis of the most relevant issues facing health care providers in the management of advanced heart failure. With content that features patient selection strategies, implantation techniques, device specific considerations, and management of clinical challenges in the post-operative setting, this textbook offers evidence-based answers to the complex questions facing nurses, perfusionists, advanced practice providers, and physicians.

Download or read book Braunwald s Heart Disease E Book written by Douglas P. Zipes and published by Elsevier Health Sciences. This book was released on 2018-01-09 with total page 2040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trusted by generations of cardiologists for the latest, most reliable guidance in the field, Braunwald’s Heart Disease, 11th Edition, remains your #1 source of information on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. This award-winning text has been completely updated, providing a superior multimedia reference for every aspect of this fast-changing field, including new material about almost every topic in cardiology.

Download or read book Encyclopedia of Intensive Care Medicine written by Jean-Louis Vincent and published by Springer. This book was released on 2012-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this comprehensive encyclopedia is to provide detailed information on intensive care medicine contributing to the broad field of emergency medicine. The wide range of entries in the Encyclopedia of Intensive Care Medicine are written by leading experts in the field. They will provide basic and clinical scientists in academia, practice, as well as industry with valuable information about the field of intensive care medicine, but also people in related fields, students and teachers will benefit from the important and relevant information on the most recent developments in emergency medicine. The Encyclopedia will contain 4 volumes, and published simultaneously online. The entire field has been divided into 14 sections. All entries will be arranged in alphabetical order with extensive cross-referencing between them.

Download or read book Magnetic Bearings for Assist Devices written by Stephen Day and published by Momentum Press. This book was released on 2015-12-16 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces magnetic bearings--mechatronic devices that produce contact-free electromagnetic force to support a load, such as a moving train or a spinning rotor. Compared to traditional bearings, magnetic bearings offer several advantages: no friction, low heat generation, no required lubrication, quiet operation, and fast and stable rotation. For these reasons, magnetic bearings have been used in rotary ventricular assist devices (VADs) to increase design life, reduce or eliminate material wear and bearing maintenance, as well as to increase biocompatibility by eliminating high fluid stresses and heat generation, both of which are associated with hemolysis, platelet activation and aggregation, and thrombus growth. The book covers the principles of these bearings, how they are used in integrated control and electronics systems, and useful information on several major brands of current assist devices.