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Book Fundamentals of Contemporary Mass Spectrometry

Download or read book Fundamentals of Contemporary Mass Spectrometry written by Chhabil Dass and published by John Wiley & Sons. This book was released on 2007-05-11 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Book Practical Aspects of Trapped Ion Mass Spectrometry  Volume IV

Download or read book Practical Aspects of Trapped Ion Mass Spectrometry Volume IV written by Raymond E. March and published by CRC Press. This book was released on 2010-05-25 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapp

Book The Use of an Ion Trap Storage reflectron Time of flight Mass Spectrometer as a Rapid and Sensitive Mass and Tandem Mass Detector for Capillary Separations

Download or read book The Use of an Ion Trap Storage reflectron Time of flight Mass Spectrometer as a Rapid and Sensitive Mass and Tandem Mass Detector for Capillary Separations written by Jingtao Wu and published by . This book was released on 1997 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Liquid Chromatography Mass Spectrometry

Download or read book Liquid Chromatography Mass Spectrometry written by Wilfried M.A. Niessen and published by CRC Press. This book was released on 2006-08-09 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: A constructive evaluation of the most significant developments in liquid chromatography-mass spectrometry (LC-MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, Liquid Chromatography-Mass Spectrometry, Third Edition offers a well-rounded coverage of the latest technological developments and

Book Theoretical and Experimental Improvements for Using an Ion Trap reflectron Time of flight Mass Spectrometer to Detect Biological Molecules

Download or read book Theoretical and Experimental Improvements for Using an Ion Trap reflectron Time of flight Mass Spectrometer to Detect Biological Molecules written by Ling He and published by . This book was released on 1997 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Practical Aspects of Ion Trap Mass Spectrometry

Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-09-18 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.

Book Development of a Quadrupole Ion Trap

Download or read book Development of a Quadrupole Ion Trap written by Beni B. Dangi and published by . This book was released on 2011 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of a tandem mass spectrometer, consisting of a quadrupole ion trap (QIT) and a time-of-flight, is described for ion mass resolution and photophysics. Ions are generated externally by electrospray ionization and trapped in the quadrupole ion trap before extraction to the time-of-flight section for mass analysis. The non-parallel fields in the hyperbolic ion trap, which serves as the first acceleration region in the time-of-flight mass spectrometer, are shown to degrade spatial focusing and mass resolution. A novel short-pulse ion extraction method is shown to be useful in diagnosis of the trapped ion cloud size, energy and dispersal time. New ion trap geometries are evaluated theoretically for improvement in mass resolution as well as ion photophysics with similar ion trapping behavior compared with the existing hyperbolic ion trap. Parameters affecting mass resolutions in linear and reflectron time-of-flight modes are identified and possible improvements are discussed. An ion trap consisting of two endcaps and two ring flat electrodes is proposed and constructed on this basis. The newly optimized design is shown to yield the mass resolution of several thousand even at room temperature with moderate extraction field. Significant improvements in ion-laser interaction and photon collection are shown in the optimized design compared to the existing hyperbolic QIT. A molecular beam source is designed, fabricated and characterized for the application in ion-molecule collision experiments. Ionization methods, from solution to gas-phase, of small polycyclic aromatic hydrocarbons are developed and compared. A photo ionization source was designed and constructed to interface in the current mass spectrometer with fast switching capability with the current electrospray source.

Book Dissertation Abstracts International

Download or read book Dissertation Abstracts International written by and published by . This book was released on 1994 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Mass Spectrometry

    Book Details:
  • Author : Jürgen H Gross
  • Publisher : Springer Science & Business Media
  • Release : 2006-04-05
  • ISBN : 3540407391
  • Pages : 534 pages

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Book Mass Spectrometry Bulletin

Download or read book Mass Spectrometry Bulletin written by and published by . This book was released on 1999 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Practical Aspects of Ion Trap Mass Spectrometry

Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC-Press. This book was released on 1995-09-18 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.

Book Practical Aspects of Trapped Ion Mass Spectrometry

Download or read book Practical Aspects of Trapped Ion Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 2010-05-25 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapping ions, such as the OrbitrapTM, the digital ion trap (DIT), the rectilinear ion trap (RIT), and the toroidal ion trap; the development and application of the quadrupole ion trap (QIT) and the quadrupole linear ion trap (LIT); and the introduction of high-field asymmetric waveform ion mobility spectrometry (FAIMS). After a combined appreciation and historical survey of mass spectrometry and a discussion of how improved capabilities for microfabrication have led to interest in arrays of ion traps, the book examines the theory and practice of the Orbitrap mass analyzer, the rectangular waveform-driven DIT mass spectrometer, FAIMS, and ion traps with circular geometries. It next discusses ion accumulation for increasing sensitivity in FT-ICR spectrometry, a radio frequency-only-mode event for Penning traps in FT MS, and an FT operating mode applied to a 3D-QIT. The text then presents three behavioral aspects of quadrupole rod sets, before illustrating the development of the 3D-QIT in recent years. The final chapters explore photodissociation in ion traps and the chemical and photochemical studies of metal dication complexes in a 3D-QIT. In this volume that spans twenty-one chapters, a stellar panel of leading experts and up-and-coming researchers presents a cohesive, global, and up-to-date view of the practical aspects of using trapped ion devices. A companion to Volume V: Applications of Ion Trapping Devices, the book authoritatively covers the theory involved as well as the instrumentation currently used in this dynamic field.

Book Analytical Instrumentation Handbook

Download or read book Analytical Instrumentation Handbook written by Jack Cazes and published by CRC Press. This book was released on 2004-11-30 with total page 1066 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiled by the editor of Dekker's distinguished Chromatographic Science series, this reader-friendly reference is as a unique and stand-alone guide for anyone requiring clear instruction on the most frequently utilized analytical instrumentation techniques. More than just a catalog of commercially available instruments, the chapters are wri