Download or read book The Comprehensive Management of Parkinson s Disease written by Matthew B. Stern and published by Pma Publishing Corporation. This book was released on 1988 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The New Parkinson s Disease Treatment Book written by J. Eric Ahlskog, PhD, MD and published by Oxford University Press. This book was released on 2015-08-03 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental guide to the most effective treatments for Parkinson's Disease, from a Mayo Clinic doctor with thirty years of clinical and research experience. In this second edition follow-up to the extremely successful first edition, Dr. Ahlskog draws on thirty years of clinical experience to present the definitive guide to dealing with all aspects of Parkinson's Disease, from treatment options and side effects to the impact of the disease on caregivers and family. Dr. Ahlskog's goal is to educate patients so that they can better team up with their doctors to do battle with the disease, streamlining the decision-making process and enhancing their treatment. To do this, Dr. Ahlskog offers a gold mine of information, distilled from his years of experience treating people with Parkinson's at the Mayo Clinic. In addition to providing a comprehensive account of Parkinson's medications, this book also examines additional aspects of treatment, such as the role of nutrition, exercise, and physical therapy. Although many commendable texts have been written on the subject of Parkinson's Disease, their discussions of treatment have not been in depth. Dr. Ahlskog sifts through aspects of the disease in order to give the reader a comprehensive sense of Parkinson's and the best available treatment options. With a broader understanding of the disease and the available options, patients are able to make more informed choices, and doctors are able to provide more tailored care. This book delivers hopeful, helpful, and extensive information to all parties concerned: patients, caregivers, and doctors. The ultimate guide to symptoms and treatment, this thoroughly updated second edition is the first place patients should turn for reliable, easy-to-grasp information on Parkinson's Disease.
Download or read book Parkinson s Disease written by Stewart A. Factor, DO and published by Demos Medical Publishing. This book was released on 2007-12-15 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease. The book includes 23 completely new chapters, and has updated information on: Genetics Pathology Biomarkers Pathogenesis Impulse control disorders in Parkinson's disease Updated outcome measures Complementary and alternative medicine for the treatment of Parkinson's disease Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose. The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.
Download or read book Diagnosis and Treatment of Parkinson s Disease written by Cindy Levine and published by Department of Health and Human Services Pu Ncy for Healthcare Res. This book was released on 2003-01-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Etiology of Parkinson s Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Download or read book Levodopa pharmacokinetics from stomach to brain written by Maria Nord and published by Linköping University Electronic Press. This book was released on 2019-01-07 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and it is caused by a loss of dopamine (DA) producing neurons in the basal ganglia in the brain. The PD patient suffers from motor symptoms such as tremor, bradykinesia and rigidity and treatment with levodopa (LD), the precursor of DA, has positive effects on these symptoms. Several factors affect the availability of orally given LD. Gastric emptying (GE) is one factor and it has been shown to be delayed in PD patients resulting in impaired levodopa uptake. Different enzymes metabolize LD on its way from the gut to the brain resulting in less LD available in the brain and more side effects from the metabolites. By adding dopa decarboxylase inhibitors (carbidopa or benserazide) or COMT-inhibitors (e.g. entacapone) the bioavailability of LD increases significantly and more LD can pass the blood-brain-barrier and be converted to DA in the brain. It has been considered of importance to avoid high levodopa peaks in the brain because this seems to induce changes in postsynaptic dopaminergic neurons causing disabling motor complications in PD patients. More continuously given LD, e.g. duodenal or intravenous (IV) infusions, has been shown to improve these motor complications. Deep brain stimulation of the subthalamic nucleus (STN DBS) has also been proven to improve motor complications and to make it possible to reduce the LD dosage in PD patients. In this doctoral thesis the main purpose is to study the pharmacokinetics of LD in patients with PD and motor complications; in blood and subcutaneous tissue and study the effect of GE and PD stage on LD uptake and the effect of continuously given LD (CDS) on LD uptake and GE; in blood and cerebrospinal fluid (CSF) when adding the peripheral enzyme inhibitors entacapone and carbidopa to LD infusion IV; in brain during STN DBSand during oral or IV LD treatment. To conclude, LD uptake is more favorable in PD patients with less severe disease and GE is delayed in PD patients. No obvious relation between LD uptake and GE or between GE and PD stage is seen and CDS decreases the LD levels. Entacapone increases the maximal concentration of LD in blood and CSF. This is more evident with additional carbidopa and important to consider in avoiding high LD peaks in brain during PD treatment. LD in brain increases during both oral and IV LD treatment and the DA levels follows LD well indicating that PD patients still have capacity to metabolize LD to DA despite probable pronounced nigral degeneration. STN DBS seems to increase putaminal DA levels and together with IV LD treatment also increases LD in brain possibly explaining why it is possible to decrease LD medication after STN DBS surgery. Parkinsons sjukdom (PS) är en av de vanligaste s.k. neurodegenerativasjukdomarna och orsakas av förlust av dopamin(DA)producerande nervceller i hjärnan. Detta orsakar motoriska symptom såsom skakningar, stelhet och förlångsammade rörelser. Levodopa (LD) är ett ämne, som kan omvandlas till DA i hjärnan och ge symptomlindring och det är oftast förstahandsval vid behandling av patienter med PS. Flera faktorer påverkar tillgängligheten av LD, bl.a. den hastighet som magsäcken tömmer sig med och denna verkar förlångsammad hos personer med PS vilket ger sämre tillgänglighet av LD i blodet och därmed i hjärnan. LD bryts även ner i hög grad av olika enzym ute i kroppen vilket leder till mindre mängd LD som hamnar i hjärnan och till fler nedbrytningsprodukter som orsakar biverkningar. Tillägg av enzymhämmare leder till ökad mängd LD som kan nå hjärnan och omvandlas till DA. Det anses viktigt att undvika höga toppar av LD i hjärnan då dessa verkar bidra till utvecklandet av besvärliga motoriska komplikationer hos patienter med PS. Om LD ges mer kontinuerligt, exempelvis som en kontinuerlig infusion in i tarmen eller i blodet, så minskar dessa motoriska komplikationer. Inopererande av stimulatorer i vissa delar av hjärnan (DBS) har också visat sig minska dessa motoriska komplikationer och även resultera i att man kan minska LD-dosen. Huvudsyftet med den här avhandlingen är att studera LD hos patienter med PS; i blod och fettvävnad då LD ges i tablettform och se om det finns något samband med LD-upptag och hastigheten på magsäckstömningen (MT) och om kontinuerligt given LD påverkar LD-upptaget eller MT; i blod och i ryggmärgsvätska då enzymhämmarna entakapon och karbidopa tillsätts LD; i hjärna vid behandling med DBS och då LD ges både som tablett och som infusion i blodet. Sammanfattningsvis kan vi se att LD-upptaget är mer gynnsamt hos patienter med PS i tidigare skede av sjukdomens komplikationsfas. MT är förlångsammad hos patienter med PS och det är inget tydligt samband mellan LD-upptag och MT eller mellan MT och sjukdomsgrad. Kontinuerligt given LD minskar LDnivåerna. Enzymhämmaren entakapon ökar den maximala koncentrationen av LD i blod och ryggmärgsvätska och effekten är mer tydlig vid tillägg av karbidopa vilket är viktigt att ta i beaktande vid behandling av PS för att undvika höga toppar av LD i hjärnan. LD ökar i hjärnan då man behandlar med LD i tablettform och som infusion i blodet och DA-nivåerna i hjärnan följer LD väl vilket visar på att patienter med PS fortfarande kan omvandla LD till DA trots trolig uttalad brist av de DA-producerande nervcellerna i hjärnan. DBS verkar öka DA i vissa områden i hjärnan och tillsammans med LD-infusion i blodet verkar det även öka LD i hjärnan och det kan förklara varför man kan sänka LDdosen efter DBS-operation.
Download or read book Parkinson s Disease written by William J. Weiner and published by JHU Press. This book was released on 2006-11-13 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent innovations, including deep brain stimulation and new medications, have significantly improved the lives of people with Parkinson’s disease. Nevertheless, medical, emotional, and physical challenges remain. The second edition of this accessible and comprehensive guide provides crucial information for managing this complex condition, including details on the use of medications, diet, exercise, complementary therapies, and surgery. The second edition includes new information about: • The genetic and hereditary pattern of the disease • Medications and uses of established medications • Other approaches to treating the symptoms of Parkinson’s • Juvenile-onset Parkinson’s disease • Normal pressure hydrocephalus • The effects of fluctuating hormones on disease symptoms • Fetal cell transplants and porcine cell transplants • The nutritional supplement Co-Enzyme Q10
Download or read book Comprehensive Nursing Care for Parkinson s Disease written by Lisette K. Bunting-Perry, MScN, RN and published by Springer Publishing Company. This book was released on 2007-04-14 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a wonderful resource for nurses and other healthcare professionals providing care for patients with Parkinson's Disease (PD)Ö.This unique book provides readers with access to multiple experts in the field and a wide variety of pertinent topics in the care of patients with PD. This is an excellent addition to the field and will be extremely useful for interdisciplinary teams caring for these patients." Score: 100, 5 stars --Doody's The incidence of Parkinson's is growing as the number of older adults making up the general population increases. The demand for nurses who specialize in the care of patients with movement disorders is also increasing and it is crucial that they have a comprehensive manual for patient care. Lisette Bunting-Perry and Gwyn Vernon have years of experience working with Parkinson's patients and have put together a team of internationally renowned clinicians who provide a truly comprehensive review of the information you need for the care of patients with this complex clinical profile. Comprehensive Nursing Care for Parkinson's Disease covers what is presently known about the disease and current evidence-based standards of care, including management through deep brain stimulation, palliative care for frail older adults with Parkinson's, medication management, nonmotor complications and psychosocial issues, and complementary and alternative approaches. This is an indispensable bedside companion in caring for those with Parkinson's as well as a much needed catalyst for the evaluation of future patient needs and the further development of comprehensive models of care.
Download or read book Navigating Life with Parkinson Disease written by Sotirios Parashos and published by Oxford University Press. This book was released on 2012-11-20 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a marvelous guide for anyone affected by Parkinson's disease--patients, caregivers, family members, and friends. Containing the most up-to-date information on the disease, one of the most common neurological disorders, it discusses the available treatments and provides practical advice on how to manage the disease in the long term. Emphasizing life-style adjustments that will provide a better quality of life and moderate the burden for patients and their loved ones, the book answers many questions and clarifies misunderstandings regarding the disease. Written by two experts on Parkinson's disease and a freelance journalist, the book is approachable and easily understandable. Question and answer sections are provided, while "hot topics" are highlighted for easy visibility. The authors have also included true patient stories that will both inspire and instruct, and they have addressed several topics often not mentioned in physician-directed disease management, such as how to talk to family and friends about one's life with Parkinson's.
Download or read book Parkinson s Disease written by National Collaborating Centre for Chronic Conditions (Great Britain) and published by Royal College of Physicians. This book was released on 2006 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diagnosis and Management of Parkinson s Disease written by Cheryl H. Waters and published by Professional Communications. This book was released on 2008-11 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the clinician with the concepts involved in effective management of Parkinson's disease. The diagnosis of PD is reviewed, as well as differential diagnosis. Pharmacologic management is the main focus of the book with detailed information on the efficacy of available drug therapies. Management of complications of PD and their therapy and surgical treatment options are reviewed.
Download or read book Non Motor Symptoms of Parkinson s Disease written by K. Ray Chaudhuri and published by Oxford University Press, USA. This book was released on 2014 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.
Download or read book Parkinson s Disease Treatment Guide for Physicians written by J. Eric Ahlskog and published by Oxford University Press, USA. This book was released on 2009 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In this book, Dr. Ahlskog provides a logical, comprehensive, and efficacious treatment approach to all aspects of this disorder. He tells the reader which drugs work best for specific problems and how to dose. Where controversies threaten to paralyze therapeutic options, he addresses these with available data, ultimately settling on those choices that can best be defended by experience and published evidence. A discussion of the role for deep brain stimulation surgery and criteria for patient selection are provided. Although focused on therapeutics, this book covers the broad needs of clinicians including diagnosing and differentiating PD from similar conditions. Testing and counseling issues are discussed in detail."--BOOK JACKET.
Download or read book Parkinson s Disease written by Paul Tuite, MD and published by Springer Publishing Company. This book was released on 2009-03-23 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: "As a quick, user-friendly reference, this book covers all aspects of effectively managing patients with Parkinson's disease, with discussions of symptoms, causes, patient evaluation, and home care adviceÖ.Nurses, physicians, and associated healthcare professions from rehabilitation specialists to social workers will find this an excellent source of information on the many aspects of care of Parkinson's disease patients." --Doody's This book serves as a practical compendium on the management issues related to Parkinson's disease (PD). As a quick, user-friendly reference, the book covers all aspects of effectively managing PD, with discussions of symptoms, causes of PD, patient evaluation, and home care advice. Conveniently organized in bullet-point, encyclopedic format, Parkinson's Disease is the comprehensive, one-stop reference for health professionals treating patients with PD. Four key sections: Problems presents guidelines on addressing complications that occur during the disease process, including anxiety, hallucinations, depression, vision problems, and more Evaluation discusses the numerous patient evaluations required throughout the duration of the illness, such as genetic testing, brain imaging, speech and swallowing evaluation, and more Treatment presents both pharmacological and non-pharmacological treatment approaches for patients with PD Appendices include supplemental reading, medication tools and assessment scales, rating scales, and additional notes Nurses, primary care doctors, and associated health care professionals--from rehabilitation specialists to social workers--will find Parkinson's Disease the one reference they cannot do without.
Download or read book Balance Dysfunction in Parkinson s Disease written by Martina Mancini and published by Academic Press. This book was released on 2019-09-14 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Balance Dysfunction in Parkinson's Disease: Basic Mechanisms to Clinical Management presents the most updated information on a variety of topics. Sections help clinicians evaluate the types of balance control issues, dynamic balance dysfunction during turning, and the effects of medication, deep brain stimulation, and rehabilitation intervention on balance control. This book is the first to review the four main postural control systems and how they are affected, including balance during quiet stance, reactive postural adjustments to external perturbations, anticipatory postural adjustments in preparation for voluntary movements, and dynamic balance control during walking and turning. In addition, the book's authors summarize the effects of levodopa, deep brain stimulation, and rehabilitation intervention for each balance domain. This book is recommended for anyone interested in how and why balance control is affected by PD. - Provides the first comprehensive review of research to date on balance dysfunctions in Parkinson's disease - Discusses how to translate current neuroscience research into practice regarding neural control of balance - Provides evidence on the effects of current interventions on balance control
Download or read book The Complete Guide for People With Parkinson s Disease and Their Loved Ones written by Lianna Marie and published by Purdue University Press. This book was released on 2020-10-15 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: A diagnosis of Parkinson’s disease is as disorienting as it is devastating. The Complete Guide for People With Parkinson’s Disease and Their Loved Ones helps make sense of what comes next and what can be done, not just for those suffering from the disease but for their family and friends as well. A trained nurse and primary caregiver for her mother, who was diagnosed with Parkinson’s disease in 1991, Lianna Marie draws upon over twenty years of education, research, and direct experience. Written in straightforward and easily accessible language, this essential guide aims to help patients better understand their role in their treatment so that they may continue to lead happy and hopeful lives. Topics covered include nutrition and exercise, alternative and complementary therapies, medication and treatment, and what caregivers can do to help. Written by an international expert on Parkinson’s who has confronted the disease firsthand, The Complete Guide serves as the go-to book for comprehensive, easy-to-understand information for all Parkinson’s patients and their loved ones.
