Download or read book The Complement System and Diabetic Kidney Disease written by Jakob Østergaard and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Complement System in Diabetic Kidney Disease written by Jakob Appel Østergaard and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Complement and Kidney Disease written by Peter F Zipfel and published by Springer Science & Business Media. This book was released on 2006-03-09 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding how complement relates to glomerular diseases has evolved considerably during the last years. Substantial evidence has accumulated that explain how a defective or deregulated complement system results in kidney diseases. The combination and close interaction of basic research with clinical medicine has demonstrated an important role of complement effector and regulatory proteins in pathological settings of the kidney. A large panel of distinct human kidney diseases such as hemolytic uremic syndrome (HUS), membrano proliferative glomerulonephritis (MPGN), systemic lupus erythematosus (SLE) and in ischemic reperfusions injury and transplantation are caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms already allowed to establish new diagnostic and novel promising therapeutic approaches for several human kidney diseases.
Download or read book Updates on the Complement System in Kidney Diseases written by Mihály Józsi and published by Frontiers Media SA. This book was released on 2023-05-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Complement System in Diabetic Kidney Disease written by Jakob Appel Østergaard and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combating Diabetes and Diabetic Kidney Disease written by Swayam Prakash Srivastava and published by Frontiers Media SA. This book was released on 2021-09-10 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diabetes and the Kidney written by Kar Neng Lai and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive update on clinical and basic aspects of diabetic nephropathy Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication at hand provides a concise overview of the current state of clinical and basic research in the field. It starts with a summary of the epidemiology and genetics of diabetic nephropathy in different ethnic groups, followed by a review of its clinical manifestation, the link with the metabolic syndrome and obesity, and the pathology of diabetic nephropathy. Building on this basis, the latest findings on pathogenetic, epigenetic and inflammatory mechanisms are presented. The publication also looks at advances in the areas of tubulopathy and the kallikrein-kinin system as well as at the latest animal models and the role of lipoproteins and proteomics. This is followed by a discussion of promising therapeutic approaches such as experimental anti-fibrotic strategies, stem cell therapy and pancreatic transplantation; expert reviews on the emerging entity of new onset diabetes after transplantation and the preventive strategies for diabetic nephropathy conclude the material presented. Written by a panel of leading international experts, this book is highly recommended for nephrologists, diabetologists, internist, transplant physicians, scientists, geneticists, epidemiologists and stem cell biologists working in the field of diabetic nephropathy.
Download or read book The Diabetic Kidney written by Pedro Cortes and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
Download or read book Renal Fibrosis Mechanisms and Therapies written by Bi-Cheng Liu and published by Springer. This book was released on 2019-08-09 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.
Download or read book Podocytopathy written by Z.-H. Liui and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
Download or read book Diabetes Mellitus written by Derek LeRoith and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
Download or read book Silva s Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Download or read book Diabetic Nephropathy written by Joris J. Roelofs and published by Springer. This book was released on 2018-10-29 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.
Download or read book Chronic Kidney Disease Dialysis and Transplantation E Book written by Jonathan Himmelfarb and published by Elsevier Health Sciences. This book was released on 2018-11-06 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains expanded content on economics and outcomes of treatment, as well as acute kidney injury. Covers hot topics such as the genetic causes of chronic kidney disease, ethical challenges and palliative care, and home hemodialysis. Discusses the latest advances in hypertensive kidney disease, vitamin D deficiency, diabetes management, transplantation, and more. Provides a clear visual understanding of complex information with high-quality line drawings, photographs, and diagnostic and treatment algorithms.
Download or read book Pathophysiology of Renal Disease written by Eberhard Ritz and published by . This book was released on 1980 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hyperacute Xenograft Rejection written by Jeffrey L. Platt and published by Springer. This book was released on 1995 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperacute rejection is defined as rejection of immediate onset which causes the rapid and inexorable decline in function of a vascularized organ graft. Until recently, hyperacute rejection was viewed as the major immunologic hurdle to the clinical application of xenotransplantation. In this monograph, the author conveys a conceptual basis for dealing with the immunological issues and pathogenesis of hyperacute rejection. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Chronic Kidney Disease written by National Collaborating Centre for Chronic Conditions (Great Britain) and published by Royal College of Physicians. This book was released on 2008 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guideline presents clear criteria for testing of chronic kidney disease, for suspecting progressive CKD and referring people for specialist assessment.
