Download or read book The Chemistry of Ynamides written by Gwilherm Evano and published by CRC Press. This book was released on 2024-06-14 with total page 733 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ynamides contain a triple bond directly connected to a nitrogen atom that bears an electron-withdrawing group. They represent an especially useful and emerging class of reagents, notably because of their strongly polarized triple bond, which enables the development of unique chemical transformations. While they were discovered by Viehe in 1972, their chemistry has remained little investigated and the renaissance of ynamide chemistry started at the dawn of the 20th century with the development of efficient methods for their synthesis. Since then, ynamide chemistry has developed at a remarkably high rate, notably in the past 20 years. Although there are several reviews on ynamide chemistry, most of them are out of date or only focus on special aspects of ynamide chemistry and there is no book about ynamide chemistry yet. Thus, a comprehensive book on ynamide chemistry would be timely and is highly needed. This book covers all aspects of ynamide chemistry, including their discovery, their syntheses, their application in heterocyclic chemistry, natural product synthesis, and organometallic chemistry, and their use as coupling reagents. It provides a systematic and comprehensive overview on ynamide chemistry for the researchers in this field, general readers interested in synthesis, and those who want to enter this field and need a comprehensive and up-to-date overview. Undoubtedly, this book will play a key role in connecting the past with the future to further foster the development of ynamide chemistry.
Download or read book The Chemistry of Ynamides and Yndiamides written by Steven Mansfield and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modern Synthesis Processes and Reactivity of Fluorinated Compounds written by Henri Groult and published by Elsevier. This book was released on 2016-11-04 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. Contains quality content edited, and contributed, by leading scholars in the field Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics
Download or read book The Chemistry of Ynamides in the Synthesis of Chiral Biaryls and Heterocycles written by Whitney Leanne Johnson and published by . This book was released on 2008 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sulfonyl Ynamides as Useful Tools for N Heterocyclic Chemistry written by Tim Wezeman and published by Logos Verlag Berlin GmbH. This book was released on 2016-12-31 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sulfonyl ynamides are highly versatile and synthetically useful reagents. This thesis details the modular synthesis and use of sulfonyl ynamides in order to access N-heterocyclic scaffolds, such as quinolines and pyrazoles. The synthesis of a wide array of sulfonyl ynamides can be realized via copper-catalyzed amidative cross-couplings or by elimination of dichloroenamide precursors. Additionally the use of Sonogashira chemistry to further diversify terminal ynamides and the synthesis of solid-supported ynamides was investigated. Electrophilically-activated amides can be reacted with sulfonyl ynamides in order to access highly functionalized 4-aminoquinolines. The straightforward amide activation procedure with triflic anhydride and 2-chloropyridine was found to tolerate a wide range of substrates, which allowed for the development of a library of 4-aminoquinolines with ease. Moreover, 4-aminopyrazoles can be prepared by reacting terminal sulfonyl ynamides with sydnones under copper catalysis. However, as the copper catalysts were also found to promote the degradation of the ynamides, a copper-free strain-promoted alternative was developed. An in situ prepared 3-azacyclohexyne was found to tolerate a wide array of C-4 substituted sydnones, producing a mixture of both the 3,4- and 4,3-fused pyrazoles in good yields. Additional investigations into heterocyclic methodology led to the development of highly sophisticated, non-symmetrical and axially-chiral dibenzo-1,3-diazepines, -oxazepines and -thiazepines from simple, commercially available anilines. The anilines were coupled to their corresponding reaction partners via a chloromethyl intermediate and the 7-membered ring was subsequently formed using direct arylation.
Download or read book Chemistry of Electron deficient Ynamines and Ynamides written by Richard P. Hsung and published by . This book was released on 2006 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Copper Mediated Cross Coupling Reactions written by Gwilherm Evano and published by John Wiley & Sons. This book was released on 2013-11-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.
Download or read book Advances in Organic Synthesis Volume 13 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-11-03 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following reviews: Electroluminescent polymers - a review on synthesis from organic compounds Remarkable advances in the asymmetric synthesis of biologically active natural compounds from the advent of chiral auxiliaries The chemistry of ynamides and their application in organic synthesis Carbon-heteroatom bond formation for medium ring heterocycles Tin(ii) salts: versatile and efficient lewis acid catalysts in reactions to add value to the glycerol and terpenic alcohols (E)-n-methyl-1-(methylthio)-2-nitroethenamine (nmsm) as a versatile ambiphilic synthon in organic synthesis.
Download or read book Synthetic Applications of 1 3 Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products Volume 59 written by Albert Padwa and published by John Wiley & Sons. This book was released on 2003-04-14 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.
Download or read book Haloalkyne Chemistry written by Huanfeng Jiang and published by Springer. This book was released on 2015-11-23 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents efficient and practical methods for the synthesis of various functionalized organic molecules from haloalkynes through different reaction processes such as cross-coupling reactions, nucleophilic additions and cycloadditions. It consists of four chapters demonstrating interesting examples of these transformations, and showcasing the synthetic power of haloalkynes for rapid assembly of complex molecular structures. Most of the protocols allow multiple bond-forming events to occur in a single operation, offering opportunities to advance chemical synthesis and address the increasing demands for green and sustainable chemistry. It also presents a wide range of functionalized products, including many synthetically useful conjugated cyclic and acyclic structures that have potential applications in materials science, chemical biology and natural product synthesis. This book is a valuable reference not only for organic chemists, but also for biologists and materials scientists involved in the modern synthesis of organic compounds and materials. Huanfeng Jiang and Wanqing Wu are both Professors at the School of Chemistry and Chemical Engineering, South China University of Technology, China. Chuanle Zhu is a Postdoctoral Fellow at the School of Chemistry and Chemical Engineering, South China University of Technology, China.
Download or read book Copper Mediated Cross Coupling Reactions written by Gwilherm Evano and published by John Wiley & Sons. This book was released on 2013-09-23 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.
Download or read book Organic Syntheses Volume 84 written by Marvin J. Miller and published by John Wiley & Sons. This book was released on 2007-10-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Syntheses: Volume 84 continues the tradition of providing significant and interesting procedures, which should prove worthwhile to many synthetic chemists working in increasingly diverse areas.
Download or read book Name Reactions written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2010-03-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.
Download or read book Catalytic Cascade Reactions written by Peng-Fei Xu and published by John Wiley & Sons. This book was released on 2013-11-11 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates the advantages of catalytic cascade reactions for synthesizing natural products and pharmaceuticals Riding the wave of green chemistry, catalytic cascade reactions have become one of the most active research areas in organic synthesis. During a cascade reaction, just one reaction solvent, one workup procedure, and one purification step are needed, thus significantly increasing synthetic efficiency. Featuring contributions from an international team of pioneers in the field, Catalytic Cascade Reactions demonstrates the versatility and application of these reactions for synthesizing valuable compounds. The book examines both organocatalysis and transition-metal catalysis reactions, bringing readers up to date with the latest discoveries and activities in all major areas of catalytic cascade reaction research. Catalytic Cascade Reactions begins with three chapters dedicated to organocatalytic cascade reactions, exploring amines, Brønsted acids, and the application of organocatalytic cascade reactions in natural product synthesis and drug discovery. Next, the book covers: Gold-catalyzed cascade reactions Cascade reactions catalyzed by ruthenium, iron, iridium, rhodium, and copper Palladium-catalyzed cascade reactions of alkenes, alkynes, and allenes Application of transition-metal catalyzed cascade reactions in natural product synthesis and drug discovery Engineering mono- and multifunctional nanocatalysts for cascade reactions Multiple-catalyst-promoted cascade reactions All chapters are thoroughly referenced, providing quick access to important original research findings and reviews so that readers can explore individual topics in greater depth. Drawing together and analyzing published findings scattered across the literature, this book provides a single source that encapsulates our current understanding of catalytic cascade processes. Moreover, it sets the stage for the development of new catalytic cascade reactions and their applications.
Download or read book Organic Syntheses Volume 96 written by John L Wood and published by John Wiley & Sons. This book was released on 2020-04-14 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.
Download or read book Organic Reaction Mechanisms 2015 written by A. C. Knipe and published by John Wiley & Sons. This book was released on 2019-02-08 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Reaction Mechanisms 2015, the 51st annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2015. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.
Download or read book Zinc Catalysis written by Stephan Enthaler and published by John Wiley & Sons. This book was released on 2015-04-27 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling the gap in the market for comprehensive coverage of this hot topic, this timely book covers a wide range of organic transformations, e. g. reductions of unsaturated compounds, oxidation reactions, Friedel-Crafts reactions, hydroamination reactions, depolymerizations, transformations of carbon dioxide, oxidative coupling reactions, as well as C-C, C-N, and C-O bond formation reactions. A chapter on the application of zinc catalysts in total synthesis is also included. With its aim of stimulating further research and discussion in the field, this is a valuable reference for professionals in academia and industry wishing to learn about the latest developments.
