Download or read book The Brain Immune Axis and Substance Abuse written by Burt M. Sharp and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of the 2nd annual symposium on the Brain Immune Axis and Substance Abuse held at the Breakers Hotel in Palm Beach, FL in June 1994. The history of productive studies concerning the relationship between the nervous and the immune systems is relatively recent. Studies on the effects of drugs of abuse on the immune system and on infections among individuals who abuse drugs are also of recent vintage. Only in the last decade have investigators begun to describe the role of drugs of abuse and their endogenous counterparts on the brain-immune axis. Thus, the involvement of the neuroendocrine system in the interactions of drugs of abuse and the immune system has only recently been appreciated. In addition, it has been recognized that direct neural inputs impact immune function. Given the complexity of these interactions, characterization of biologically significant phenomena and elucidation of their mechanisms of action often requires a multidisciplinary approach. This meeting, on which the chapters in this book are based, brought together scientists from an array of biomedical disciplines whose work is focused on the effects of drugs of abuse on the neuro-endocrine immune axis. The meeting was unique in focusing on the brain-immune axis from the viewpoint of drugs of abuse rather than either immunity itself or the brain itself. Presentations addressed the direct effects of drugs of abuse on various components of the immune system, as well as those mediated indirectly by the central nervous system and the neuroendocrine system.

Download or read book AIDS Drugs of Abuse and the Neuroimmune Axis written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the Proceedings of the Symposium on AIDS, Drugs of Abuse and the Neuroimmune Axis. This meeting was held in San Diego, California, November 11-13, 1995. As in the previous symposia in this series, productive studies were reviewed concerning the relationship between the nervous and the immune systems in regards to the relationship between drugs of abuse and infections, especially infections by the immunode ficiency virus that causes AIDS. In recent years, various investigators have begun to describe the role of illicit drugs and their endogenous counterparts on the brain-immune axis. It is widely recognized that the neuroendocrine system is intimately involved in the effects and manifestations of the interactions of drugs of abuse and the immune system. The meeting on which the chapters in this book are based brought together many biological scientists from an array of various scientific disciplines whose work is focused on the effects of drugs of abuse on the neuroendocrine-immune axis and its relationships to immunodeficiency caused by the AIDS virus. As in the past, the symposium was unique in focusing on the . brain-immune axis from the viewpoint of drugs of abuse rather than from the viewpoint of immunity or the brain itself.

Download or read book Neuroimmune Circuits Drugs of Abuse and Infectious Diseases written by Herman Friedman and published by Springer. This book was released on 2013-03-23 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Perspectives This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, Oc- ber 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the effects of drugs of abuse and infections, including AIDS, caused by the immunodeficiency virus. Presentations discussed the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The major aim of this series of conferences has been to clarify the consequences of immunomodulation induced by drugs of abuse in regards to susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. The recreational use of drugs of abuse such as morphine, cocaine, and marijuana by large numbers of individuals in this country and around the world has continued to arouse serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune responses. Much of the recent data accumulated by investigators show that drugs of abuse, especially opioids and cannabinoids, markedly alter immune responses in human populations as well as in experimental animals, both in vivo and in vitro.

Download or read book Drugs of Abuse Immunomodulation and Aids written by Herman Friedman and published by Springer. This book was released on 2012-11-22 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Perspectives This volume represents the Proceedings of the Fifth Annual Symposium on Drugs of Abuse, Immunomodulation, and AIDS. The meeting was held in Nashville, Tennessee, June 12-14, 1997. In this symposium, as in the past, newer knowledge was reviewed concerning the relationship between the immune and the nervous systems with regard to the effects of drugs of abuse. This symposium focused on the relationship between the immune system and the nervous system with regard to the effects of drugs of abuse and infections such as the immunodeficiency virus that causes AIDS. As in the past symposia, presentations fo cused on the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The aim of this series of conferences has been to clarify the consequences ofimmunomodulation induced by drugs of abuse on susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. Recreational use of drugs of abuse, such as morphine, cocaine, and marijuana, as well as alcohol, by large numbers of individuals in this country and around the world has aroused serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune mechanisms. It is now widely known that many drugs of abuse, including marijuana, are used by millions ofindi viduals in this country and by even more abroad.

Download or read book Drugs of Abuse Immunomodulation and Aids written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Perspectives This volume represents the Proceedings of the Fifth Annual Symposium on Drugs of Abuse, Immunomodulation, and AIDS. The meeting was held in Nashville, Tennessee, June 12-14, 1997. In this symposium, as in the past, newer knowledge was reviewed concerning the relationship between the immune and the nervous systems with regard to the effects of drugs of abuse. This symposium focused on the relationship between the immune system and the nervous system with regard to the effects of drugs of abuse and infections such as the immunodeficiency virus that causes AIDS. As in the past symposia, presentations fo cused on the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The aim of this series of conferences has been to clarify the consequences ofimmunomodulation induced by drugs of abuse on susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. Recreational use of drugs of abuse, such as morphine, cocaine, and marijuana, as well as alcohol, by large numbers of individuals in this country and around the world has aroused serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune mechanisms. It is now widely known that many drugs of abuse, including marijuana, are used by millions ofindi viduals in this country and by even more abroad.

Download or read book Neuroimmune Circuits Drugs of Abuse and Infectious Diseases written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Perspectives This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, Oc- ber 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the effects of drugs of abuse and infections, including AIDS, caused by the immunodeficiency virus. Presentations discussed the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The major aim of this series of conferences has been to clarify the consequences of immunomodulation induced by drugs of abuse in regards to susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. The recreational use of drugs of abuse such as morphine, cocaine, and marijuana by large numbers of individuals in this country and around the world has continued to arouse serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune responses. Much of the recent data accumulated by investigators show that drugs of abuse, especially opioids and cannabinoids, markedly alter immune responses in human populations as well as in experimental animals, both in vivo and in vitro.

Download or read book Drugs of Abuse Immunity and Infections written by Herman Friedman and published by CRC Press. This book was released on 1995-12-18 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past few decades, drugs of abuse, including marijuana, cocaine, opiates, and alcohol have been studied in detail by biomedical scientists in terms of their effects on the neurophysiology and psychological responses of individuals. Research over the last few years has provided increased knowledge about possible mechanisms by which such drugs increase the likelihood of infections in humans and experimental animals. In Drugs of Abuse, Immunity, and Infections prominent investigators review important new information concerning the effects of recreational drugs on susceptibility to infection by microorganisms. The volume examines the effects of drugs such as cocaine, morphine, marijuana, and opiates on immunity in humans and animals. It covers the molecular and cellular mechanisms of drug-induced immunosuppression and describes the overall enhanced susceptibility to infection in recreational drug users. It discusses the alteration of susceptibility to the retrovirus that causes the acquired immunodeficiency syndrome (AIDS) and the consensus that drugs of abuse may serve as a possible cofactor in the progression of AIDS. Drugs of Abuse, Immunity, and Infections also includes important information concerning public health aspects of drugs of abuse and infection.

Download or read book Drug Abuse in the Decade of the Brain written by Gabriel G. Nahas and published by IOS Press. This book was released on 1997 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life scientists have declared the 1990s to be the "Decade of the Brain." Undoubtedly the most important organ, the brain is perhaps the least understood. Until recently, the proper methodology for exploring the basic functions of the brain were not available. However, the new era of computer technology brain imaging and molecular biology have given scientists the tools for studying previously hidden mechanisms of the brain which control thinking, emotions, and behavior. Along with this new knowledge, scientists have observed that drugs of abuse can alter these same brain functions in a profound and persistent manner. Drugs of abuse are widely used substances that differ in chemical nature but have a common property-creating dependence. Dependence is characterized by a stereotypical pattern of behavior oriented toward the search, acquisition, and ingestion of drugs of abuse with such frequency and in such quantity as to be harmful. This behavior is beyond the control of reason and will. Studies conducted during the "decade of the brain" or before, show that the clinically observed, dependent behavior induced by drugs of abuse result from neurophysiological and chemical alterations of complex brain mechanisms. These mechanisms involve the production and turnover of the brain neurotransmitters that carry information in the brain neurocircuitry, changes in brain metabolism and circulation, and alterations in the expression of DNA which programs the functions or the neuronal cell. This book describes a number of newly discovered basic brain mechanisms and the alterations caused by drugs of abuse. Contributions by top researchers in fields of radian biology, biochemistry, genetics, and pharmacology examine the new technological improvements for the measurement of brain function, metabolism, blood flow and drug elimination and report changes in brain biochemistry, including DNA expression, as they occur during drug abuse. Physicians and health professionals will benefit from a better understanding of the effects of drugs on the brain which will lead to more effective interventions for prevention and treatment. Highlights include: New knowledge about the brain New methods of investigation Opiates and the brain Marijuana and the brain Cocaine and the brain This book will be of interest to health professionals and program administrators involved in the education and treatment of substance abuse disorders, as well as physicians, nurses, psychiatric social workers, neuroscientists, and pharmacologists.

Download or read book Problems of Drug Dependence written by College on Problems of Drug Dependence (U.S.). Scientific Meeting and published by . This book was released on 1992 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Problems of Drug Dependence written by and published by . This book was released on 2001 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microbes and the Mind written by C.S.M. Cowan and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-06 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1995 with total page 1732 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Homeostatic Control of Brain Function written by Detlev Boison and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurotrophic Factors written by Gary R. Lewin and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.

Download or read book Neuroimmunoendocrinology written by J. Edwin Blalock and published by Karger Medical and Scientific Publishers. This book was released on 1997-01-01 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of information on immuneneuroendocrine interactions has continued unabated since the first and second editions of this volume appeared in 1988 and 1992. This third revised and enlarged edition offers an authoritative update on the latest advances in knowledge of the molecular, structural, and cellular bases of bidirectional communication between the immune and neuroendocrine systems. The eight invited chapters review current evidence that the immune system produces and responds to neuroendocrine peptide hormones and neurotransmitters; that the nervous system produces and responds to cytokines; that the immune system can regulate the neuroendocrine system and vice versa; that the immune system is innervated, and that the neuroendocrine and immune systems share a set of hormone and cytokine receptors. All chapters and bibliographies from the second edition have been expanded to include the most recent literature in these areas. In addition, the text provides a new chapter which is the first to compare the three-dimensional structures of cytokines and hormones complexed with their receptors. As the only text to provide an up-to-the-minute account of the cellular, molecular and structural mechanisms of communication between the immune and neuroendocrine systems, this well-written volume will be of interest to many scientists in the fields of immunology, endocrinology, physiology, neuroscience and structural biology, and will also be a valuable resource for clinicians.

Download or read book Pathology of the Gastrointestinal Tract written by Fátima Carneiro and published by Springer. This book was released on 2017-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the complete field of the pathology of the Gastrointestinal tract - from Abetalipoproteinemia to Zollinger-Ellison Syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.