Download or read book The Biophysical Approach to Excitable Systems written by William J. Adelman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 10, 1980, Kenneth S. Cole became 80 years old. In order to celebrate this landmark, a symposium in the form of a series of Monday evening lectures was held in his honor at the Marine Biological Labora tory throughout the summer of 1980. The selection of speakers was made from among those investigators who had been either his students or co-workers. One intent of the symposium was to examine the current status of knowledge of those areas of interest in excitable membrane structure and function that owe their initiation or encouragement to Kacy Cole. The papers assembled in this volume represent a large majority of the presentations given during the 1980 Cole Symposium. It seems clear on examination of these papers that Kacy's interests in membrane impedance, ion channel conductances, channel fluctuation phenomena, excitation, and the development of membrane biophysical methodology are all being actively pursued. It is also clear that many of his suggestions have borne fruit. Of these, his invention of the voltage v vi Preface clamp method has been most productive. It is hoped that these papers will provide new directions for investigations into the nature of excitable membrane phenomena. The organizers of the symposium and the editors of this volume wish to express their thanks to the Marine Biological Laboratory for making available the facilities for the symposium. They also wish to thank Dr.
Download or read book Squid as Experimental Animals written by W.J., Jr. Adelman and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: The predecessor to this book was A Guide to the Laboratory Use of the Squid Loligo pealei published by the Marine Biological Laboratory, Woods Hole, Massachusetts in 1974. The revision of this long out of date guide, with the approval of the Marine Biological Laboratory, is an attempt to introduce students and researchers to the cephalopods and particularly the squid as an object of biological research. Therefore, we have decided to expand on its original theme, which was to present important practical aspects for using the squid as experimental animals. There are twenty two chapters instead of the original eight. The material in the original eight chapters has been completely revised. Since more than one method can be used for accomplishing a given task, some duplication of methods was considered desirable in the various chapters. Thus, the methodology can be chosen which is best suited for each reader's requirements. Each subject also contains a mini-review which can serve as an introduction to the various topics. Thus, the volume is not just a laboratory manual, but can also be used as an introduction to squid biology. The book is intended for laboratory technicians, advanced undergraduate students, graduate students, researchers, and all others who want to learn the purpose, methods, and techniques of using squid as experimental animals. This is the reason why the name has been changed to its present title. Preceding the chapters is a list of many of the abbreviations, prefixes, and suffixes used in this volume.
Download or read book Structure and Function in Excitable Cells written by Donald Cheng and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of up-to-date research reviews dealing with various aspects of the structure and function of excitable cells. Its overall objective is to further the search for a better understanding of the mechanism of excitation on a structural and physicochemical basis. The chapters are written by active investigators from a variety of disciplines, repre senting many different points of view. Their complementary fields of expertise give this book the rare feature of extraordinary breadth. Excitability is a fundamental property of many biological systems. The mechanisms by which nerve impulses are initiated and propagated, and by which rhythmical activities are produced in nerve, muscle, and cardiac cells, can be fully elucidated only when the process of excitation is derived from fundamental principles applied to known structural forms, at both the macroscopic and the molecular level. The problems of excitation are complex, requiring knowledge of many aspects of cells, including their morphology, elec trobiology, chemical physics, and biochemistry.
Download or read book Voltage Sensitive Ion Channels written by H. Richard Leuchtag and published by Springer Science & Business Media. This book was released on 2008-12-21 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Voltage-sensitive ion channels are macromolecules embedded in the membranes of nerve and muscle fibers of animals. Despite decades of intensive research under the traditional approach of gated structural pores, the relation between the structure of these molecules and their function remains enigmatic. This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.
Download or read book Biophysical Approaches written by Edward D. Korn and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: The short period since the publication of Volume 1 of Methods in Membrane Biology has been a time of momentous progress. Calorimetry, electron spin and nuclear magnetic resonance, X-ray diffraction, and freeze-cleavage electron microscopy, reinforced by biochemical analyses and enzymatic studies, have led to universal acceptance of a generalized membrane model. All membrane biologists would agree that a major element of all biological membranes is a bilayer of phospholipids which, in some instances, also contains other lipids, notably sterols and glycolipids. The fatty acid com position of the lipids of most membranes is such that the lipids are above their transition temperatures in their normal environment so that the bilayer is fluid. The microviscosity of the fatty acyl groups decreases pro gressively down the chain so that, at the hydrocarbon interior of the bilayer, the lipid phase has a viscosity approximating that of olive oil at room temperature. As a consequence of this membrane fluidity, a phospholipid molecule is very mobile within the plane of the membrane (moving a distance of about 1-2 fLm in 1 s) but the movement of a phospholipid molecule from one side of the membrane bilayer to the other (flip-flop) is very slow. The lipid bilayer is an essentially inert and rather impermeable struc ture, as shown by many studies with model systems. Proteins, of course, provide the catalytic components of the membranes. as well as playing a significant structural role.
Download or read book Molecular and Colloidal Electro optics written by Stoyl P. Stoylov and published by CRC Press. This book was released on 2016-04-19 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Colloidal Electro-Optics presents cohesive coverage from internationally recognized experts on new approaches and developments in both theoretical and experimental areas of electro-optic science. It comprises a well-integrated yet multi-disciplinary treatment of fundamental principles, strategies, and applications of electro-op
Download or read book Current Topics in Membranes and Transport written by and published by Academic Press. This book was released on 1984-06-30 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes and Transport
Download or read book Neurobiology and Cell Physiology of Chemoreception written by P.G. Data and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume records the papers presented in Chieti, Italy, at the 1991 meeting of the International Society for Arterial Chemoreception (ISAC). This was the eleventh of a series of assemblies held since 1959. This field of research, which examines the critical function and mechanisms of O and pHIPC0 sensitive cells in 2 2 the body, is unique in that it encompasses diverse biological and medical areas. The reader of this book will note chapters concerning modem techniques like in situ hybridization; analysis of cell membrane channels and intracellular ion movements; immunohistochemistry of peptides, hormones, and the corresponding receptors of chemoreceptor cells; and systemic analysis of reflex pathways involving chemoreceptor cells and their meaning in health and disease. This broad spectrum will appeal to readers interested in the chemoreceptor field, as well as young scientists seeking a scientific field where not only structural analysis but also a sense for functional connections is required. In recognition of the importance of the contribution of a new scientific generation to this field, ISAC awarded the prestigious F. de Castro-C. Heymans E. Neil prize to A. G6rlach, a young scientist. Also at this meeting, the Ferdinando Data Foundation Award, for helping scientists from non-developed countries to pursue their interest in chemoreception, was initiated. ISAC held plenary lectures in honor of C. Eyzaguirre and R. Forster, both of whom have contributed greatly to research in the chemoreceptor field.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book CRC Handbook of Biological Effects of Electromagnetic Fields written by Charles Polk and published by CRC Press. This book was released on 2019-07-23 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to present in a concise manner what is actually known at the present time about biological effects of time invariant, low frequency and radio frequency (including microwave) electric and magnetic fields. In reviewing the vast amount of experimental data which have been obtained in recent years, the authors tried to select those results that are, in their opinion, of major importance and of lasting value. In discussing mechanisms of interaction of electromagnetic fields with living matter they have tried to differentiate between what is clearly established, what is suggested by available evidence without being convincingly proven, and what is conjecture at the present time.
Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.) and published by . This book was released on 1983 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue lists papers published during the preceding year.
Download or read book Statistical reference book of international activities written by United States. National Institutes of Health and published by . This book was released on 1983 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biophysics written by and published by Academic Press. This book was released on 1982-11-16 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics
Download or read book Cancer Biochemistry Biophysics written by Harry Darrow Brown and published by . This book was released on 1982 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Exploring the Cell Membrane Conceptual Developments written by A. Kleinzeller and published by Newnes. This book was released on 2012-12-02 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The suggestion for this collection of essays originated in part from a course given to graduate students at the University of Pennsylvania School of Medicine. In sections of this course, the conceptual developments in the fields of membrane transport and cellular respiration were traced to illustrate general aspects of the development of ideas in a scientific field. Discussions with peers on the topic also greatly enhanced the development of the project as it is reflected in this book. The volume reflects the breadth and scope of this rapidly developing field, and is an excellent treatise of a historical evaluation of how this field has developed.
Download or read book Dynamics of Complex Autonomous Boolean Networks written by David P. Rosin and published by Springer. This book was released on 2014-12-31 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on the dynamics of autonomous Boolean networks, on the basis of Boolean logic functions in continuous time without external clocking. These networks are realized with integrated circuits on an electronic chip as a field programmable gate array (FPGA) with roughly 100,000 logic gates, offering an extremely flexible model system. It allows fast and cheap design cycles and large networks with arbitrary topologies and coupling delays. The author presents pioneering results on theoretical modeling, experimental realization, and selected applications. In this regard, three classes of novel dynamic behavior are investigated: (i) Chaotic Boolean networks are proposed as high-speed physical random number generators with high bit rates. (ii) Networks of periodic Boolean oscillators are home to long-living transient chimera states, i.e., novel patterns of coexisting domains of spatially coherent (synchronized) and incoherent (desynchronized) dynamics. (iii) Excitable networks exhibit cluster synchronization and can be used as fast artificial Boolean neurons whose spiking patterns can be controlled. This work presents the first experimental platform for large complex networks, which will facilitate exciting future developments.
