Download or read book The Biologic Role of Dehydroepiandrosterone DHEA written by M. Kalimi and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "The Biologic Role of Dehydroepiandrosterone (DHEA)".
Download or read book The DHEA Biological System written by Nuel Nenji and published by Independently Published. This book was released on 2023-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both the adrenal glands, which are situated on top of each kidney, are responsible for the production of the steroid hormone known as dehydroepiandrosterone (DHEA). It has a role in the creation of other hormones, such as testosterone and estrogen, by acting as a precursor. As people get older, their levels of DHEA tend to steadily decrease after reaching their peak in early adulthood. Over the years, DHEA has garnered attention in a variety of fields, including the control of mood, the process of aging, and overall health and wellness. On the other hand, some individuals take DHEA supplements in an effort to improve their athletic performance or to address concerns that are associated with aging. On the other hand, the scientific evidence that supports the usefulness and safety of DHEA supplementation is not absolutely conclusive, and the effects that occur over a longer period of time are not completely known. It is essential to keep in mind that DHEA is regarded as a prohibited substance in certain countries; hence, the inclusion of this ingredient in dietary supplements must to be addressed with caution. When contemplating the use of any hormonal supplement, it is recommended to first consult with a qualified medical practitioner in order to evaluate the potential risks and benefits of the supplement based on the specific health requirements and conditions of the individual.
Download or read book Dehydroepiandrosterone written by Gerald Litwack and published by Academic Press. This book was released on 2018-07-31 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dehydroepiandrosterone, Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrosterone Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrosterone, Mutation of HSD3B2 Gene and Fate of Dehydroepiandrosterone, Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrosterone Promotes Beneficial Effects on Human Health, Dehydroepiandrosterone and Cardiovascular Disease, Dehydroepiandrosterone and Experimental Osteoarthritis, The Role of Dehydroepiandrosterone (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrosterone, and more. Focuses on the newest aspects of hormone action in connection with diseases Lays the groundwork for the focus of new chemotherapeutic targets Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways
Download or read book Nutritional and Herbal Therapies for Children and Adolescents written by George M. Kapalka and published by Academic Press. This book was released on 2009-11-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume assists practicing mental health professionals in expanding their knowledge about nutritional and herbal interventions that can be attempted as alternatives to prescription medications. Designed to provide guidance for non-medical caregivers treating children and adolescents who present with emotional and/or behavioral difficulties such as such as depression, anxiety, ADHD, sleep difficulties, impulsivity, distractibility, and other psychological and psychiatric disorders, the volume provides a comprehensive discussion of naturopathic solutions based on existing research. In areas where research is not extensive, conclusions are provided about potentially beneficial effects based on the specific pharmacologic action of the compounds. Dosage for specific age groups, schedules of administration, dietary considerations (i.e., whether or not to take the supplement with food), monitoring for response and adverse effects, signs of dangerous reactions, and the need to control interactions with other compounds (i.e., prescription medications) are thoroughly reviewed with regard to each supplement discussed in the book. Reviews specific psychological disorders (i.e. ADHD, depression, mania, anxiety, sleep difficulties, tic behaviors and autism) and the available data about their treatment with the use of nutritional and herbal supplements Provides rationale for the use of every specific compound with detailed recommendations tailored for each age group with regard to the dosage, frequency of administration, possible dangers and monitoring for side effects Discusses claims of efficacy used to market various products and ground those claims within fully vetted scientific research Discusses neurobiology, pharmacodynamics and pharmokinetics in detailed but accessible language *Non-medical clinicians with limited knowledge of medicine and pharmacology come away with understanding of key issues involved in Fully covers assessment, diagnosis & treatment of children and adolescents, focusing on evidence-based practices *Consolidates broadly distributed literature into single source and specifically relates evidence-based tools to practical treatment, saving clinicians time in obtaining and translating information and improving the level of care they can provide Detailed how-to explanation of practical evidence-based treatment techniques *Gives reader firm grasp of how to more effectively treat patients Material related to diversity (including race, ethnicity, gender and social class) integrated into each chapter *Prepares readers for treating the wide range of youth they will encounter in practice
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Download or read book Dehydroepiandrosterone and Its Metabolites written by Qianxing Mo and published by . This book was released on 2005 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dehydroepiandrosterone (DHEA) is a multi-functional neurosteroid that has been implicated in a variety of biological effects in humans and other mammals. The mechanism of action of DHEA has not been fully elucidated, although it is under investigation as a replacement therapy for humans with DHEA Insufficiency based on reports suggesting beneficial effects ranging from anti-depression to neuroprotection. Controversy remains about the relative contribution of DHEA and its metabolites in its biological effects. This dissertation focuses on a comparative study of the genomic effects of DHEA and its metabolites in vitro, and identification of genes regulated by DHEA in vivo. The results indicated that DHEA, androstenediol and androstenedione produced typical genomic effects, including promoting AR-GFP intracellular trafficking and formation of nuclear clusters in COS-7 cells, and conferred AR transcriptional activity in a dose-dependent manner in transiently transfected CV-1 cells. In contrast, DHEAS, 7alpha-OH-DHEA, 7beta-OH-DHEA, and 7-oxo-DHEA were essentially without androgenic activity. The results confirmed that DHEA is intrinsically androgenic and demonstrated significant differences in androgenic activity among DHEA and its metabolites. In the hypothalamus, DHEA, like the strongest androgen DHT, significantly up-regulated the expression of two important neuropeptides: hypocretin (Orexin) and pro-melanin concentrating hormone precursor (Prepro-MCH), and delta type protein kinase C (PKCdelta), and down-regulated the expression of deleted in bladder cancer chromosome region candidate 1 (DBCCR1) and chitinase 3-like 3 (Chi3l3). Interestingly, DHT down-regulated the expression of PKCS in the hippocampus. The differential expression of Prepro-MCH, orexin, and PKCdelta was further confirmed by real-time RT-PCR. MCH and orexin are involved in the regulation of appetite and energy homeostasis, and PKCdelta and DBCC1 are involved in regulation of cell growth, proliferation or survival. More importantly, the functions of these genes may explain the multiple effects of DHEA in humans and rodents. The findings may be of clinical significance and provide a new level of detail concerning the mechanism of action of DHEA in the central nervous system.
Download or read book DHEA written by Ray Sahelian and published by Avery. This book was released on 1996 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Hormone, Disease, Mood and energy, and more.
Download or read book Sex Hormones in Neurodegenerative Processes and Diseases written by Gorazd Drevensek and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
Download or read book Basic Medical Endocrinology written by H. Maurice Goodman and published by Lippincott Williams & Wilkins. This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Contemporary Practice in Clinical Chemistry written by William Clarke and published by Academic Press. This book was released on 2020-06-11 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. Includes enhanced illustration and new and revised color figures Provides improved self-assessment questions and end-of-chapter assessment questions
Download or read book Goodman s Basic Medical Endocrinology written by Elizabeth H. Holt and published by Academic Press. This book was released on 2021-02-21 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. Clinical case studies in every chapter E-book version available with every copy for obtaining images and tables for lectures or notes Clinicians added as co-authors to enhance usefulness by physicians and medical students and residents Detailed molecular biology of hormones and hormone action for graduate and advanced undergraduate students Expanded and updated color images emphasizing hormone action at the molecular level In-depth molecular biology and clinical sections boxed for ease of access
Download or read book Treatment of the Postmenopausal Woman written by Rogerio A. Lobo and published by Elsevier. This book was released on 2007-06-05 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: For anyone who treats postmenopausal women, this latest edition of Rogerio Lobo's classic work combines the best from two well-known references: Menopause, and the second edition of Treatment of the Postmenopausal Woman. By adding significant discussions of the basic science behind menopause, it is possible to objectively assess the clinical value and limitations of current approaches to treatment and provide a basis and rationale for strategies that will result in better individualized and specialized care. Not only does the third edition discuss diagnosis and treatment of menopause but it covers biological, anatomical, physiological, pathobiological, and pharmacological aspects as well bringing together, in one source, all of the information needed to understand and treat postmenopausal conditions. Over 50% new material representing the vast amount of information available since the Women's Health Initiative (WHI) clinical trials were completed making this the most up-to-date reference on postmenopausal women Includes several new sections on comparisons between clinical trials and observational data, urology, and pelvic support Each section is preceded by a preface to put the area into context with many chapters having suggested treatment regimens
Download or read book The Hypothalamus Pituitary Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later
Download or read book Synthesis of Best Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Download or read book Steroids written by Sergej Ostojic and published by BoD – Books on Demand. This book was released on 2012-11-21 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroids - From Physiology to Clinical Medicine covers contemporary basic science on steroids research, along with steroids practical application in clinical medicine. We start by describing physiological and pathophysiological roles of steroids, with reference to production and action of gonadal steroids, role of steroid sulfonation, sex specific and steroids-dependent mechanism of hippocampal function, and the hydroxysteroid dehydrogenases for the modulation of tissue glucocorticoid availability. We then covered different aspects of steroids application in clinical environment, such as endocrine function after ovarian transplantation, diagnostic significance of salivary assessment of androgens, drawbacks of steroids use in sport, analysis of serum steroid hormone profiles in patients with adrenocortical tumors, and correlation between salivary and serum cortisol responses after alcohol intake. In response to the need to address novel and valuable information on steroids science and medicine, we sincerely hope that this book will enable readers to comprehend this fast-growing and exciting scientific discipline.
Download or read book Salivary Bioscience written by Douglas A. Granger and published by Springer Nature. This book was released on 2020-04-07 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.
Download or read book Handbook of Crime Correlates written by Lee Ellis and published by Academic Press. This book was released on 2009-05-07 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two centuries, many aspects of criminal behavior have been investigated. Finding this information and making sense of it all is difficult when many studies would appear to offer contradictory findings. The Handbook of Crime Correlates collects in one source the summary analysis of crime research worldwide. It provides over 400 tables that divide crime research into nine broad categories: Pervasiveness and intra-offending relationships Demographic factors Ecological and macroeconomic factors Family and peer factors Institutional factors Behavioral and personality factors Cognitive factors Biological factors Crime victimization and fear of crime Within these broad categories, tables identify regions of the world and how separate variables are or are not positively or negatively associated with criminal behavior. Criminal behavior is broken down into separate offending categories of violent crime, property crime, drug offenses, sex offenses, delinquency, general and adult offenses, and recidivism. Accompanying each table is a description of what each table indicates in terms of the positive or negative association of specific variables with specific types of crime by region. This book should serve as a valuable resource for criminal justice personnel and academics in the social and life sciences interested in criminal behavior.
