Download or read book The BALB c Mouse as a Model for Protective Immunity to Brugia Pahangi written by Allison J. Bancroft and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The BALB c Mouse written by Michael Potter and published by Springer. This book was released on 1985-08 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse was first used in immunological research by Paul Ehrlich in 1891 in an extraordinary series of experiments on the maternal transfer of antitoxic immunity. A short 22 years later in 1913 Halsey Bagg acquired a stock of albino mice from a commercial dealer and used them in a series of experiments on learning. Because he was interested in the genetics of intelligence, Halsey Bagg began breeding a pedigreed line of these mice that were subsequently named for him - Bagg Albino. Though Halsey Bagg is not credited with initiating the inbred strains of mice, his stock curiously has played an indisputably important role. Bagg Albinos were progenitors of the present day BALB/c family of sublines - the subject of this book. They were also used as one of the parents in the development of inbred strains A, CBA and C3H, three other very famous strains. Today the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research. The hallmark of the BALB/c response to so many kinds of infections is susceptibility and sometimes an exaggerated susceptibility, but this paradoxically is not associated with immunodeficiency as BALB/c is an excellent responder to immuni zation. These characteristics have made the BALB/c mouse a model for identifying genes that determine susceptibility to infectious and neoplastic diseases. In 1985 the laboratory BALB/c mouse became 72 years old. The current filial generations are somewhere around 350 generations [MURPHY].
Download or read book Human and Animal Filariases written by Ronald Kaminsky and published by John Wiley & Sons. This book was released on 2023-01-24 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human and Animal Filariases The rational approach to controlling human and animal diseases caused by nematodes Filariae are a family of parasitic worms which infect animals and humans, causing severe diseases such as elephantiasis (lymphatic filariasis) and river blindness (onchocerciasis) in humans, as well as heartworm disease (dirofilariasis) in dogs and cats. While the human diseases are rarely fatal, the blindness and disfiguration resulting from these infections constitute a severe burden for the affected individuals and to the healthcare systems in many tropical countries. In 2017, the World Health Organization classified several filariases as neglected tropical diseases and announced a new program seeking to eradicate these infections, which has in turn sparked a new push to develop antifilarial drugs. Considering the current and future import of this topic, Human and Animal Filariases takes a comprehensive look at infections by filarial parasites in humans and in animals. It begins by reviewing the current state of diagnosis and chemotherapy, before addressing the increasing resistance to available antifilarial drugs. This is followed by strategies and approaches for the discovery of novel drugs and finally by looking at alternative and supplementary approaches to combat the parasites, including vector control and vaccination. Human and Animal Filariases readers will find: A comprehensive approach that integrates current chemotherapy with recent advances in antifilarial drug discovery Practical information on assay development, target validation, and required drug product profiles Insights from global experts from leading academic institutions as well as from pharma and healthcare companies Human and Animal Filariases is a unique reference for parasitologists, veterinarians, as well as professionals in the pharmaceutical industry and in public health agencies.
Download or read book Lymphatic Filariasis written by Brij Kishore Tyagi and published by Springer. This book was released on 2018-11-03 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphatic Filariasis (LF) is a group of human and animal infectious diseases caused by nematode parasites of the order Filariidae. Often neglected, it is one of the oldest and the most debilitating tropical diseases (NTDs), transmitted from human to human by mosquitoes bites, particularly the brown black mosquito known as Culex quinquifasciatus. LF is a major public health problem in many parts of the tropics, especially India, which accounts for as much as 40% of total global cases. As a leading cause of permanent and long-term disability worldwide, the parasite infection imposes a severe physical and socioeconomic burden. The World Health Organization (WHO) estimates that 1.4 billion people live in high-risk areas – 120 million of which are already infected with LF, including 22 million children below the age of 15 and about 76 million who suffer from damaged lymphatic and renal systems. India has made great strides toward eliminating the disease, and these advances are of global significance. They include early diagnosis mechanisms, vaccine product development, detection of parasites in the vector, and studies on parasite evolution trends in nature as warning signals. Reports on the successes and failures are needed to enable measures to be taken to avoid disaster and ensure a smooth transition from endemicity in India to the elimination of lymphatic filariasis by 2020. This book, which gathers highly original contributions on various subjects related to lymphatic filariasis, discusses the latest scientific research that will help the nation to achieve this milestone. It also serves as a guide to many other countries struggling against this highly debilitating and incapacitating disease.
Download or read book The American Journal of Tropical Medicine and Hygiene written by and published by . This book was released on 1989 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lymphatic Filariasis written by D G Addiss and published by World Scientific. This book was released on 2000-01-15 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first in a series dedicated to the understanding of tropical diseases. This volume examines the basic biology and clinical expression of lymphatic-dwelling filarial parasites, parasites affecting over 128 million people in the tropical and subtropical regions of the world. Although it is responsible for the disfiguring elephantiasis, infection with this parasite leads to a spectrum of clinical manifestations. The underlying pathogenetic mechanisms of infection, its epidemiology, diagnosis, treatment and prevention of this often devastating vector-borne diseases will be the focus of this book.
Download or read book How Helminths Alter Immunity to Infection written by William Horsnell and published by Springer. This book was released on 2014-09-24 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helminth infections are common, cause considerable pathology, and alter a host’s immune profile. This can have important consequences not only on the host’s ability to control a helminth infection, but also on their ability to control unrelated infections. In endemic areas, understanding how helminth infection influences the outcome of common infectious diseases and changes the efficacy of childhood vaccination programs is an important public health question. This book reviews how host immunity to helminths alters our ability to respond to the major pathogens that exist in helminth endemic regions. Current understanding of how helminths alter important but relatively neglected contributors to the host’s anti-helminth immune responses are addressed, namely host antibody responses and how maternal infection may alter a child’s immune development. These are discussed in relation to the control of helminth infection and unrelated infections. Also covered are how helminth infections alter the host’s ability to control TB, HIV and malarial infections along with neglected bacterial infections, such as cholera, and how endemic helminth infections are likely to alter our ability to respond to life-saving vaccination strategies.
Download or read book Studies of Brugia Pahangi Filarioidea Larval Antigens and Related Monoclonal Antibodies written by Xiqiang Hong and published by . This book was released on 1990 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Trichinella and Trichinellosis written by Fabrizio Bruschi and published by Elsevier. This book was released on 2021-07-22 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trichinella and Trichinellosis provides an up-to-date account of the nematode Trichinella spp., including infections and diseases caused by this parasite in both animals and humans. This book will fill the long gap in time during which an exhaustive monograph on this subject has been missing in the international literature. The chapters have been written by the most prolific researchers in the world on the different aspects of Trichinella and trichinellosis. This book serves as an original resource for research on Trichinella and trichinellosis, exploring cutting-edge advances on such parasites and the infections they cause. This book will be a valuable resource for students, biologists, epidemiologists, veterinarians, physicians, and scientists involved in the study of the parasites of the Trichinella genus and their related diseases. It will be particularly helpful for those who are beginning their research in this fascinating field. Offers a broad overview on the parasites belonging to the Trichinella genus Presents recent cutting-edge advances on this zoonotic parasite, focusing on the molecular epidemiology, systematics of the parasite, clinical aspects of the diseases, and the roadmap to the control of infection in domestic pigs Discusses ground-breaking approaches designed to meet the medical needs in trichinellosis
Download or read book The Journal of Immunology written by and published by . This book was released on 2008 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book British Reports Translations and Theses written by British Library. Document Supply Centre and published by . This book was released on 1994 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issue for Mar. 1981 contains index for Jan.-Mar. 1981 in microfiche form.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transactions of the Royal Society of Tropical Medicine and Hygiene written by Royal Society of Tropical Medicine and Hygiene and published by . This book was released on 1991 with total page 966 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tropical Diseases Bulletin written by and published by . This book was released on 1995 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunoparasitology written by Phillip Scott and published by . This book was released on 2004 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Parasitology written by and published by Academic Press. This book was released on 1987-07-22 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Parasitology
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
