Download or read book The Aryl Nitrene Intermediate written by James Wagy Hill and published by . This book was released on 1968 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitrenes and Nitrenium Ions written by Daniel E. Falvey and published by John Wiley & Sons. This book was released on 2013-04-10 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring contributions respected leaders in the field, Nitrene and Nitrenium Ions is the first comprehensive book to explore the role of reactive intermediate nitrene and nitrenium ions in chemistry and biochemistry. Covering a broad range of topics, including ultrafast studies, computational studies, behavior in aqueous solution, electronic structures, and reactions with aromatic compounds, this valuable resource will empower graduate students and researchers to better understand and expand their synthetic utility.
Download or read book Organic reactive intermediates written by Samuel McManus and published by Elsevier. This book was released on 2012-12-02 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry: A Series of Monographs, Volume 26: Organic Reactive Intermediates focuses on the study of reactive intermediates. This book discusses the methods of formation and investigation, factors affecting the stability, and reactions of the intermediate. Other topics include the formation and reaction of free radicals; kinetic aspects of free-radical chain reactions; electronic states and structures of carbenes; and formation of transient carbenes and carbenoids in solution. The intermediacy of nitrenes in reactions; electronic structure and spectra; methods of investigating carbonium ions; and reactions of carbonium ions are also elaborated. This publication likewise covers the preparation of carbanions; factors affecting the stability of carbanions; reactions involving radical ions; and methods of investigating arynes. This volume serves as a textbook for the first graduate-level course, as well as a reference for industrial chemists interested in organic reaction mechanisms.
Download or read book Seven Membered Intermediates in the Isomerisation of Aryl Carbenes and Nitrenes written by Anthony Robert Lea and published by . This book was released on 1972 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aziridines and Epoxides in Organic Synthesis written by Andrei K. Yudin and published by John Wiley & Sons. This book was released on 2006-02-20 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.
Download or read book Photochemically Generated Intermediates in Synthesis written by Angelo Albini and published by John Wiley & Sons. This book was released on 2013-07-01 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the latest applications of photochemistry to generate important intermediates Presenting the latest breakthroughs in the field of organic photochemistry, this book offers tested and proven photochemical approaches to synthesis, creating promising new possibilities and applications for photochemical reactions. It focuses on photoreactions involving an intermediate where mechanistic aspects control the course of the reaction and its synthetic value. Readers will discover new insights into the mechanisms and nature of photo-produced reactive intermediates for organic synthesis as well as the methods to generate them. Moreover, by focusing on highly efficient techniques for producing such species, the authors enable researchers to design and perform photoreactions within the framework of green, sustainable chemistry. Photochemically-Generated Intermediates in Synthesis begins with a discussion of the principles and practice of photo-generated intermediates. Next, the book explores: Photogeneration of carbon-centered radicals Photogeneration of heteroatom-centered radicals Photogeneration of biradicals and radical pairs Photochemical generation of radical ions Photogeneration of carbocations and carbanions Photogeneration of carbenes and nitrenes The book's final chapter is dedicated to the photochemical manipulation of intermediates. Each chapter includes key kinetic data for typical intermediates as well as detailed case examples, giving readers all the tools needed to perform their own photochemical reactions. Comparisons to non-photochemical methods are offered whenever possible. Photochemically-Generated Intermediates in Synthesis sets the stage for greater collaboration among photochemists and synthetic organic chemists, enabling these two research communities to fully leverage photochemistry in order to generate key intermediates needed for a broad range of synthetic reactions in organic chemistry.
Download or read book Reactive Intermediates written by R.A. Abramovitch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of reactive intermediates has been blossoming at a rapid rate in recent years and its impact on chemistry, both "pure" and "applied," as well as on biology, astronomy, and other areas of science, is enormous. Several books have been published which cover the area; one, edited by McManus, * surveys the subject in general at the senior undergraduate or beginning graduate level. In addition, a number of monographs have appeared which deal with individual topics such as carbenes, nitrenes, free radicals, carbanions, carbenium ions, and so on, in great depth. Our objective is somewhat different. We hope that these Advances in . . . type of volumes will appear at irregular intervals of a year to 18 months each. We intend to publish up-to-date reviews in relatively new areas of the chemistry of reactive intermediates. These will be written by world authorities in the field, each one of whom will give the reader a current in-depth review of all aspects of the chemistry of each of these species. It is our plan that the subjects to be reviewed will cover not only organic chemistry but also inorganic, physical, bio-, industrial, and atmospheric chemistry. The volumes themselves, we hope, will end up being reasonably interdisciplinary, though this need not and probably will not be the case for the individual reviews.
Download or read book Reactive Intermediates in Organic Chemistry written by Maya Shankar Singh and published by John Wiley & Sons. This book was released on 2014-01-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most reactions in organic chemistry do not proceed in a single step but rather take several steps to yield the desired product. In the course of these multi-step reaction sequences, short-lived intermediates can be generated that quickly convert into other intermediates, reactants, products or side products. As these intermediates are highly reactive, they cannot usually be isolated, but their existence and structure can be proved by theoretical and experimental methods. Using the information obtained, researchers can better understand the underlying reaction mechanism of a certain organic transformation and thus develop novel strategies for efficient organic synthesis. The chapters are clearly structured and are arranged according to the type of intermediate, providing information on the formation, characterization, stereochemistry, stability, and reactivity of the intermediates. Additionally, representative examples and a problem section with different levels of difficulty are included for self-testing the newly acquired knowledge. By providing a deeper understanding of the underlying concepts, this is a musthave reference for PhD and Master Students in organic chemistry, as well as a valuable source of information for chemists in academia and industry working in the field. It is also ideal as primary or supplementary reading for courses on organic chemistry, physical organic chemistry or analytical chemistry.
Download or read book Organic Reaction Mechanisms 2016 written by A. C. Knipe and published by . This book was released on 2020-01-14 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Reaction Mechanisms 2016, the 52nd annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2016. The following classes of organic reaction mechanisms are comprehensively reviewed: * Reaction of Aldehydes and Ketones and their Derivatives * Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives * Oxidation and Reduction * Carbenes and Nitrenes * Nucleophilic Aromatic Substitution * Electrophilic Aromatic Substitution * Carbocations * Nucleophilic Aliphatic Substitution * Carbanions and Electrophilic Aliphatic Substitution * Elimination Reactions * Polar Addition Reactions * Cycloaddition Reactions * Molecular Rearrangements
Download or read book Transition Metal Dinitrogen Complexes written by Yoshiaki Nishibayashi and published by John Wiley & Sons. This book was released on 2019-05-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive book that explores nitrogen fixation by using transition metal-dinitrogen complexes Nitrogen fixation is one of the most prominent fields of research in chemistry. This book puts the focus on the development of catalytic ammonia formation from nitrogen gas under ambient reaction conditions that has been recently repowered by some research groups. With contributions from noted experts in the field, Transition Metal-Dinitrogen Complexes offers an important guide and comprehensive resource to the most recent research and developments on the topic of nitrogen fixation by using transition metal-dinitrogen. The book is filled with the information needed to understand the synthesis of transition metal-dinitrogen complexes and their reactivity. This important book: -Offers a resource for understanding nitrogen fixation chemistry that is essential for explosives, pharmaceuticals, dyes, and all forms of life -Includes the information needed for anyone interested in the field of nitrogen fixation by using transition metal-dinitrogen complexes -Contains state-of-the-art research on synthesis of transition metal-dinitrogen complexes and their reactivity in nitrogen fixation -Incorporates contributions from well-known specialists and experts with an editor who is an innovator in the field of dinitrogen chemistry Written for chemists and scientists with an interest in nitrogen fixation, Transition Metal-Dinitrogen Complexes is a must-have resource to the burgeoning field of nitrogen fixation by using transition metal-dinitrogen complexes.
Download or read book Azides and Nitrenes written by Eric Scriven and published by Elsevier. This book was released on 2012-12-02 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Azides and Nitrenes: Reactivity and Utility provides information pertinent to the fundamentals aspects of the chemistry of azides and nitrenes. This book discusses the mechanism and synthetic applications of alkyl azides. Organized into 10 chapters, this book begins with an overview of the properties and chemistry of alkyl azides and alkylnitrenes. This text then examines the various pathways to the preparation of vinyl azides. Other chapters consider the magnetic resonance spectrum of phenyl azide, which may be taken as a representative to which more complex examples can be related. This book discusses as well the acyl azides and acylnitrenes that have their nitrogen function attached to electron-withdrawing groups not possessing a heteroatom bearing an unshared electron pair next to the nitrogen function. The final chapter deals with the main uses for organic azides involved in photochemical cross-linking of polymeric systems. This book is a valuable resource for chemists, spectroscopists, and theoreticians.
Download or read book Catalytic Reductive Carbonylation of Organic Nitro Compounds written by S. Cenini and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: About eight years ago, the catalytic carbonylation of organic nitro compounds was a research field developed enough to justify a rather long review on this subject. Now, we feel that the scientific results and new achievements in this field, very important even from an industrial point of view, require a book in order to be adequately presented. The competition between the catalytic carbonylation of organic nitro compounds and other chemical routes for the synthesis of a variety of organic compounds has not yet come to an end, but many progresses have been done in the former field. We also like to emphasize that this type of research does not only involve relevant industrial problems to be solved, but it opens a research field where the academic interests (mechanism of the reactions, isolation of the intermediates in the catalytic cycles, synthesis of model compounds and so on) can find a lot of opportunities.
Download or read book Handbook of Heterocyclic Chemistry written by Alan R. Katritzky and published by Elsevier. This book was released on 2010-08-24 with total page 1011 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts Features 35% new material to compliment the completely revised text
Download or read book Reviews of Reactive Intermediate Chemistry written by Matthew S. Platz and published by John Wiley & Sons. This book was released on 2007-04-20 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry of reactive intermediates is central to a modern mechanistic and quantitative understanding of organic chemistry. Moreover, it underlies a significant portion of modern synthetic chemistry and is integral to a molecular view of biological chemistry. Reviews in Reactive Intermediate Chemistry presents an up-to-date, authoritative guide to this fundamental topic. Although it follows Reactive Intermediate Chemistry by the same authors, it serves as a free-standing resource for the entire chemical and biochemical community. The book includes: Relevant, practical applications Coverage of such topics as mass spectrometry methods, reactive intermediates in interstellar medium, quantum mechanical tunnelling, solvent effects, reactive intermediates in biochemical processes, and excited state surfaces Discussions of emerging areas, particularly those involving dynamics and theories Concluding sections identifying key directions for future research are provided at the end of each chapter
Download or read book Advanced Organic Chemistry written by Francis A. Carey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main theme of Part B is the description of synthetically useful reactions and the illustration of their application. We have attempted to update the material to reflect the most important advances in synthetic methodology. Because of the extensive developments in the use of organic derivatives of transition metals, as well as of silicon and tin, we have separated the organometallic material into three chapters. Chapter 7 emphasizes organolithium and organomagnesium chemistry and also considers the group lIB metals. Transition metal chemistry is discussed in Chapter 8, with emphasis on copper and palladium intermediates. In Chapter 9, the carbon-carbon bond-forming reactions of organoboranes, silanes, and stannanes are discussed. The increased importance of free-radical reactions in synthesis has led to the incorporation of a section on radical reactions into Chapter 10, in which carbocations, carbenes, and nitrenes are also discussed. Certainly a major advance in synthetic chemistry during the 1980s was the development of methods for enantioselective synthesis. We have increased the level of attention to stereochemistry in the discussion of many reactions. In areas in which new stereoselective methods have been well developed, such as in aldol condensa tions, hydroboration, catalytic reduction, and epoxidation, we discuss these methods. The final chapter discusses some of the general issues which must be addressed in multistep synthesis and provides some illustrative syntheses which can provide the basis for more detailed study of this aspect of synthetic chemistry.
Download or read book Copper Carbenes and Nitrenes written by and published by . This book was released on 2009 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of synthetic reactions that are efficient for the construction of carbon-carbon and carbon-heteroatom bonds is an important goal in contemporary organic and inorganic synthetic chemistry. Late-transition metal carbenes and nitrenes serve as highly valuable synthetic intermediates for useful catalytic transformations such as the [2 + 1] addition to olefins to give cyclopropanes and aziridines respectively. The direct and selective functionalization of C-H bonds to C-C or C-N bonds is also known to proceed via the intermediacy of such key intermediates. The quest for the identification of such valuable catalytic intermediates has been proven difficult due to their general thermal instability and high reactivity. Herein we describe the isolation and characterization of discrete copper carbene and nitrene species that exhibit electrophilic character and can undergo catalytic group transfer reactions with nucleophilic substrates. The synthesis of a family of dinuclear copper(I) beta-diketiminate arene complexes that can activate organoazides has led to the stabilization of diverse nitrene [NR] ligands (R = aryl, aliphatic, acyl) and the crystallographic characterization of discrete dicopper nitrene complexes. The detailed synthetic studies allowed us to uncover a unique and an efficient copper catalyzed C-H amination protocol using organoazides as a nitrene precursor. High turnover numbers (900) can be achieved for the amination of ethylbenzene. A novel 'C-H' protected robust betadiketiminato copper(I) catalyst was synthesized and was found to catalyze nitrene [NR] insertion into C-H bonds of hydrocarbons, ethers and aldehydes. The rate of C-H amination is strongly correlated to the strength of the reacting C-H bond and was found dependent on the choice of nitrene [NR] substituent. Copper-catalyzed amination reactions of several C-H substrates with aryl azides and benzoyl azide were undertaken. The first three-coordinate Cu(II) primary amido species were isolated and characterized and were shown to be highly reactive towards C-H bonds. The ability to study metal-stabilized carbene and nitrene species provides many valuable insights towards its diverse reactivity pathways and opens an avenue for the development of novel catalytic processes.
Download or read book Bioconjugate Techniques written by Greg T. Hermanson and published by Academic Press. This book was released on 2010-07-26 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions
