Download or read book Transgenerational Epigenetics written by and published by Academic Press. This book was released on 2019-05-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.
Download or read book Tetrahymena Thermophila written by Kathleen Collins and published by Academic Press. This book was released on 2012-03-28 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Cell Biology looks at Tetrahymena thermophila, a model organism in experimental biology. Covering sections on Systems perspectives and Operating principles, chapters are written by experts in the field. With cutting edge material, this comprehensive collection is intended to guide researchers of Tetrahymena thermophila for years to come. Covers sections on systems perspectives and operating principles Chapters are written by experts in the field Cutting-edge material, making this a truly comprehensive collection
Download or read book The Ciliated Protozoa written by Denis Lynn and published by Springer Science & Business Media. This book was released on 2008-06-24 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: distances between groups of ciliates were as vast as significant hurdles to obtain copyright permissions the genetic distances between plants and animals for the over 1,000 required illustrations, and I put – THE major eukaryotic kingdoms at that time! the publication schedule ahead of this element. I continued to collaborate with Mitch, and in There are a number of significant illustrated guides 1991 my first “molecular” Magisterial student, to genera and species that have recently been pub- Spencer Greenwood, published an article estab- lished. References are made to these throughout lishing 1990 or thereabouts as the beginning of the book as sources that readers can consult for this the “Age of Refinement” – the period when gene aspect of ciliate diversity. A future project that I am sequencing techniques would deepen our under- contemplating is an illustrated guide to all the valid standing of the major lines of evolution within ciliate genera.
Download or read book Essays Upon Heredity and Kindred Biological Problems written by August Weismann and published by . This book was released on 1891 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Molecular Biology of Ciliated Protozoa written by Joseph G. Gall and published by . This book was released on 1986 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of Ciliated Protozoa covers topics that are unique to ciliates, including major molecular progress, genetics, life history, and development of ciliates. Organized into 11 chapters, it focuses on the importance of ciliated protozoa as experimental organisms. The introductory chapter traces the ups and downs of ciliate biology, emphasizing the prominent role of the ciliates in early studies of cell structure, reproduction, and heredity. The book goes on to discuss ciliate genetics and conjugation, providing the basic biological framework for molecular studies of ciliate. Ch ...
Download or read book Biocommunication of Ciliates written by Guenther Witzany and published by Springer. This book was released on 2016-05-23 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first coherent description of all levels of communication of ciliates. Ciliates are highly sensitive organisms that actively compete for environmental resources. They assess their surroundings, estimate how much energy they need for particular goals, and then realise the optimum variant. They take measures to control certain environmental resources. They perceive themselves and can distinguish between ‘self’ and ‘non-self’. They process and evaluate information and then modify their behaviour accordingly. These highly diverse competences show us that this is possible owing to sign(aling)-mediated communication processes within ciliates (intra-organismic), between the same, related and different ciliate species (inter-organismic), and between ciliates and non-ciliate organisms (trans-organismic). This is crucial in coordinating growth and development, shape and dynamics. This book further serves as a learning tool for research aspects in biocommunication in ciliates. It will guide scientists in further investigations on ciliate behavior, how they mediate signaling processes between themselves and the environment.
Download or read book Marine Genetics written by Antonio M. Solé-Cava and published by Springer Science & Business Media. This book was released on 2000-05-31 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Workshop on Marine Genetics - Rio 98
Download or read book Beyond the Gene written by Jan Sapp and published by Oxford University Press. This book was released on 1987-05-14 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope and significance of cytoplasmic inheritance has been the subject of one of the longest controversies in the history of genetics. In the first major book on the history of this subject, Jan Sapp analyses the persistent attempts of investigators of non-Mendelian inheritance to establish their claims in the face of strong resistance from nucleo-centric geneticists and classical neo-Darwinians. A new perspective on the history of genetics is offered as he explores the conflicts which have shaped theoretical thinking about heredity and evolution throughout the century: materialism vs. vitalism, reductionism vs. holism, preformation vs. epigenesis, neo-Darwinism vs. new-Lamarckism, and gradualism vs. saltationism. In so doing, Sapp highlights competitive struggles for power among individuals and disciplinary groups. He accepts that political interests and general social contexts may directly affect scientific ideas, but develops the stronger thesis that social interests inside science itself are always involved in the content of scientific knowledge. He goes on to show that there are no neutral judges in scientific controversies and investigates the social strategies and methodological rhetoric used by scientists when they defend or oppose a particular theory. At the same time, Sapp illustrates the social constraints that ensure the high cost and risk of entertaining unorthodox theories in the sciences.
Download or read book Pattern Formation written by Joseph Frankel and published by Oxford University Press, USA. This book was released on 1989 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive review of pattern formation in ciliates, along with an analysis of general mechanisms of pattern formation. The author emphasizes the integrative mechanisms that encompass the entire cell surface, and pays particular attention to genetic and non-genetic mirror-image reversals of asymmetry. A conceptual model for large-scale intracellular organization is included. The perspective derived from ciliate studies is applied to the early development of multicellular organisms, particularly embryos of Drosophilia. The book will be accessible to developmental biologists with no prior familiarity with ciliates.
Download or read book Guidelines for the Identification of Ciliates in Wastewater Treatment Plants written by Susana Serrano and published by IWA Publishing. This book was released on 2008-02-01 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ciliated protozoa are one of the most relevant biological communities in the reactors of wastewater treatment plants. These organisms are excellent tools to assess the biological status of the reactor being used to monitor wastewater treatment plants performance. This book has been designed to simplify identification of ciliates, bearing in mind the difficulties on the manipulation and proper identification of these species. The specific role of ciliates in WWTP is discussed; methods for observation together with a glossary of scientific words and a simple and easy key to the taxonomic groups of ciliates are also provided. Illustrations, drawings, photographs and brief morphological descriptions of the species are included. Guidelines for the Identification of Ciliates in Wastewater Treatment Plants is the first book to use the new official classification proposed by the Society of Protozoologists (2005). It includes a complete chapter on methodology that is designed to be easy to follow and reproduce. A simple key to classify main taxonomic groups and genera is included, as are detailed descriptions to aid observation and identification of species of ciliates, in addition to drawings and photographs that accurately reproduce ciliate species.
Download or read book The Evolution of Anisogamy written by Tatsuya Togashi and published by Cambridge University Press. This book was released on 2011-04-14 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Darwin identified the existence of separate male and female gametes as one of the central mysteries of evolutionary biology. 150 years later, the question of why male gametes exist remains an intriguing puzzle. In this, the first book solely devoted to the evolution of anisogamy, top theorists in the field explore why gamete dimorphism characterizes nearly all plants and animals. Did separate male and female gametes evolve as a result of competition, or does anisogamy instead represent selection for cooperation? If disruptive selection drove the evolution of anisogamy, with male gametes focused on search and fusion, and female gametes provisioning the new zygote, why do some algal species continue to produce gametes of a single size? Does sperm limitation, or escape from infection, better explain the need for extremely small, highly mobile sperm? Written by leaders in the field, this volume offers an authoritative and cutting-edge overview of evolutionary theory.
Download or read book Of Urfs And Orfs written by Russell F. Doolittle and published by University Science Books. This book was released on 1986 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In these days of facile cloning and rapid DNA sequencing, it is not uncommon for investigators to find themselves with a DNA sequence that may or may not code for a known gene product. The sequence is 'open' when read in an appropriate frame, which is to say that there is a long run of amino acid codons before the appearance of a terminator codon. How can we find out if this 'unidentified reading frame' (URF) really codes for a genuine protein, and how can we identify it if it exists? There are two general strategies, both of which can also be applied to the characterization of any 'open reading frame' (ORF), whether or not it has been 'identified'. The first and simplest approach involves computer searching and analysis; the second employs antibodies raised against synthetic peptides patterned on the sequence of the expected gene product. Both methods have been used with great success by many investigators. Each has, nonetheless, its pitfalls and frustrations. This primer is meant to guide the researcher past those obstacles as much as possible. Graduate students and researchers interested in amino acid sequencing; molecular biologists, biochemists, chemists, and biotechnologists.
Download or read book Dispersal Ecology and Evolution written by Jean Clobert and published by OUP Oxford. This book was released on 2012-09-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now that so many ecosystems face rapid and major environmental change, the ability of species to respond to these changes by dispersing or moving between different patches of habitat can be crucial to ensuring their survival. Understanding dispersal has become key to understanding how populations may persist. Dispersal Ecology and Evolution provides a timely and wide-ranging overview of the fast expanding field of dispersal ecology, incorporating the very latest research. The causes, mechanisms, and consequences of dispersal at the individual, population, species, and community levels are considered. Perspectives and insights are offered from the fields of evolution, behavioural ecology, conservation biology, and genetics. Throughout the book theoretical approaches are combined with empirical data, and care has been taken to include examples from as wide a range of species as possible - both plant and animal.
Download or read book MCQs in Microbiology written by G. Vidya Sagar and published by New Age International. This book was released on 2008 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Management of Legionella in Water Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-02-20 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.
Download or read book Epigenetics written by C. David Allis and published by CSHL Press. This book was released on 2007 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
Download or read book Modified Nucleic Acids in Biology and Medicine written by Stefan Jurga and published by Springer. This book was released on 2016-07-29 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. Alkylation and oxidation show a potential to disrupt the cellular redox equilibrium and cause cellular damage leading to inflammation and even chronic disease. Furthermore, DNA damage can drive mutagenesis and the resulting DNA sequence changes can induce carcinogenesis and cancer progression. Modified nucleosides can occur as a result of oxidative DNA damage and RNA turnover, and are used as markers for various diseases. To function properly some RNA needs to be chemically modified post-transcriptionally. Dysregulation of the RNA-modification pattern or of the levels of the enzymes that catalyze these modifications alters RNA functionality and can result in complex phenotypes, likely due to defects in protein translation. While modifications are best characterized in noncoding ribonucleic acids like tRNA and rRNA, coding mRNAs have also been found to contain modified nucleosides. This book is a valuable resource, not only for graduate students but also researchers in the fields of molecular medicine and molecular biology.
