Download or read book Teratogen Update written by John L. Sever and published by . This book was released on 1986 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Teratogenic Mechanisms written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. This book brings together some of the more recent and important research findings related to the mechanisms and pathogenesis of abnormal develop ment. It is not only a documentation of the latest experimental work, but it also points out future directions that seem productive and challenging.
Download or read book Catalog of Teratogenic Agents written by Thomas H. Shepard and published by JHU Press. This book was released on 2004 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Links information on experimental teratogenic agents with the congenital defects in human beings.
Download or read book Teratogenic Effects of Drugs written by Jan Marshall Friedman and published by . This book was released on 2000 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This new edition will continue to serve as a reference for use by clinical and research geneticists, teratologists, obstetricians, and pediatricians."--BOOK JACKET.
Download or read book Potter s Pathology of the Fetus Infant and Child written by Edith Louise Potter and published by Mosby. This book was released on 2007 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference addresses all aspects of fetal and neonatal pathology, including complicated pregnancies, multiple pregnancies, abortion, placental pathology, and disorders affecting the full-term neonate. A consistent organization allows for quick access to specific guidance, and nearly 2,500 illustrations - 2,350 in full color - depict conditions and abnormalities as they present in practice, facilitating diagnosis. An Image Bank on CD-ROM - new to this edition - features all of the illustrations from the 2-volume set, downloadable for presentations. Offers comprehensive coverage of all common and rare embryonic, fetal, and infant disorders in one source. Correlates clinical, pathologic, and genetic findings for each systemic disease. Emphasizes the genetic and molecular basis of birth defects. Features nearly 2,500 illustrations - 2,350 in full color - which depict each abnormality or condition as they present in practice. Presents practical information on autopsy techniques and protocols. Provides the latest guidance on molecular pathology, immunohistochemistry, DNA technology, and more. Offers an expanded discussion of developmental biology related to the pathogenesis of birth defects. Features user-friendly summary tables and diagnostic flow charts, making information quick and easy to find. Includes a CD-ROM featuring all of the illustrations from the 2-volume set.
Download or read book Health Risks of Radon and Other Internally Deposited Alpha Emitters written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Download or read book Teratogenesis and Reproductive Toxicology written by E.M. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several disoiplines such as developmental and molecu lar biology, pathology, pharmacology and toxicology, pediatrics and neonatology, and epidemiology. More recently we h~ve seen an emergence of interest in other fields such as perinatal physiology and postnatal behavior which have now become incorporated into the mainstream of research in this discipline. The present volume is an effort to provide a sampling of concepts currently under active investigation in several of the above fields. The authors have endeavored to provide up-to-date in formation on the following topics: detection and analysis of potential hazards to the conceptus in the workplace, pharmacokinetic aspects of the maternal/placental! fetal complex and its relationship to human birth defects, and probable mechanisms of teratogenesis as uncovered in certain well-defined situations. Also included are summaries of newer investigations on the emerging field of postnatal functional evaluations, i. e. , adverse effects on adult activities resultant from in utero exposure to toxic substances.
Download or read book The Oxford Handbook of Externalizing Spectrum Disorders written by Theodore P. Beauchaine and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The Oxford Handbook of Externalizing Spectrum Disorders' is the first book of its kind to capture the developmental psychopathology of externalizing spectrum disorders by examining causal factors across levels of analysis and developmental epochs, while departing from the categorical perspective.
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Download or read book Drugs and Pregnancy written by Bertis Little and published by CRC Press. This book was released on 2006-09-29 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical handbook will assist the physician and nurse prescriber in understanding the effects of drug exposure during pregnancy. Numerous tables and boxes provide information on drug classifications and regimens, as well as highlighting adverse effects and TERIS and FDA risk ratings. Sources of further information are provided where appropria
Download or read book In Vitro Methods in Developmental Toxicology written by Gary L. Kimmel and published by CRC Press. This book was released on 2019-06-04 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1990, this text brings together the work of several investigators who used in vitro techniques to probe the nature of embryonic cell response to a diverse group of chemical agents. It focuses on the approaches, limitations, usefulness and applicability of defining mechanisms underlying altered development. This work includes discussions on pharmacodynamic principles and placental transfer mechanisms. It also examines the potential for in vitro systems to serve as an adjunct to the risk assessment process. Ideal for both the layman and the expert in this area, this volume provides a general understanding of the types of approaches that can be used and specific approaches in investigating altered development.
Download or read book Human Developmental Toxicants written by James L. Schardein and published by CRC Press. This book was released on 2006-08-15 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the first database of its kind, this unique reference illustrates the relationships between the chemistry and developmental toxicity of a number of important pharmaceuticals and industrial toxicants. Human Developmental Toxicants contains up-to-date and concise information on the chemical structures, properties, and biological activities
Download or read book Clinical Obstetrics written by E. Albert Reece, MD, PhD, MBA and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 1560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly Commended in the Obstetrics and Gynaecology category atthe British Medical Association Book Awards 2008 The third edition of Clinical Obstetrics - The Fetus andMother is unique in that it gives in-depth attention to the twopatients – fetus and mother, giving special coverage to eachpatient. Clinical Obstetrics - The Fetus and Mother coversthe biology, pathology, and clinical management of disordersaffecting the fetus and the mother with illustrations highlightingessential diagnostic features and treatment procedures. The bookhas been extensively revised and in some cases reorganized forclarity and flow. This book is fully up to date with specialchapters on; first trimester prenatal screening 3-D and 4-D ultrasound medical and surgical fetal therapy foetal stem cell therapy prenatal diagnosis and fetal developmental biology benign tumors in pregnancy and extensive discussion of each of the main areas of maternaldiseases. The book has been made more succinct yet heavilyannotated and illustrated giving greater clinical emphasis enablingfast decisions at the point of care; all chapters now have keysummary points making it easy to retrieve information. In addition Clinical Obstetrics - The Fetus and Motherincludes a new searchable CD of the text including over 100 colourillustrations, and a Q&A book allowing you to test yourlearning. Formerly known as Medicine of the Fetus and Mother and highlysuccessful in two previous editions published by Lippincott
Download or read book Metal Ions in Biology and Medicine written by Philippe Collery and published by John Libbey Eurotext. This book was released on 1998-06-05 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every two years, the world's leading specialists meet to exchange information on the most recent advances in understanding metals and the part they play in treating some diseases, especially cancer. Most of the elements in our environment are metals. Some are essential for life, such as copper, iron, magnesium, manganese, nickel and zinc; others are toxic, such as arsenic, cadmium, lead and mercury. This book aims to help advance our knowledge of the role of metal ions in a number of fields in biology and medicine. It reproduces the papers given at the International Symposium on Metal Ions in Biology and Medicine organised in Munich in May 1998.
Download or read book Creasy and Resnik s Maternal Fetal Medicine E Book written by Charles J. Lockwood and published by Elsevier Health Sciences. This book was released on 2022-09-07 with total page 1877 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference in the field for more than 35 years, Creasy and Resnik's Maternal-Fetal Medicine provides today's MFM practitioners with authoritative, comprehensive guidance on every aspect of this fast-changing field. The fully revised 9th Edition brings you up to date with the latest evidence-based guidelines and research as well as the fundamental scientific foundation needed for effective practice, helping you minimize complications and ensure the best possible outcomes for your patients. Renowned experts in obstetrics, gynecology, and perinatology provide valuable information in every area of complex obstetric care, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management. - Offers comprehensive updates on rapidly changing topics, including extensively revised genetic content throughout. - Includes two new chapters: maternal and fetal viral infections, including COVID-19; and sexually transmitted disease, covering the epidemiology, pathogenesis, diagnosis, and treatment of individual infectious diseases that may complicate pregnancy. - Contains user-friendly features such as numerous diagnostic and treatment algorithms for quick access to current protocols; key points at the end of each chapter; and counseling pearls with practical guidance on patient consultation. - Features a comprehensive imaging section, including a video library to aid in everyday diagnosis. - Shares the expertise of a renowned editorial team—including new co-editors Drs. Lorraine Dugoff and Judette M. Louis—who lead authors representing top institutions from around the globe. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Download or read book Reproductive Hazards in the Workplace written by and published by . This book was released on 1994 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fetal Disorders written by Boris M. Petrikovsky and published by John Wiley & Sons. This book was released on 1999 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gathers insights from a variety of specialties-genetics, pediatrics, infectious diseases, neonatology, and obstetrical ultrasound-to present integrated protocols for detecting and treating a range of fetal disorders. The anomalities discussed in will be divided into those that are incompatible with life, those that require utero intervention, and those that require postmatal intervention. A detailed clinical protocol and management algorithm will be presented for each anomaly and include the following components: definition and classification; incidence and epidemiology; major principles of diagnosis; recommendations for in utero management; counseling and prognosis; and a bibliography.
